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Academisch Ziekenhuis Leiden H o d n Lumc patents


Recent patent applications related to Academisch Ziekenhuis Leiden H o d n Lumc. Academisch Ziekenhuis Leiden H o d n Lumc is listed as an Agent/Assignee. Note: Academisch Ziekenhuis Leiden H o d n Lumc may have other listings under different names/spellings. We're not affiliated with Academisch Ziekenhuis Leiden H o d n Lumc, we're just tracking patents.

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Hpv epitopes targeted by t cells infiltrating cervical malignancies for use in vaccines

The present invention relates to novel CD4+ and CD8+ T cell epitopes that are specific for HPV-specific E6 and E7 oncoproteins, to peptides comprising these novel T cell epitopes, and to (vaccine) compositions comprising these peptides for use in methods for the prevention and/or treatment of HPV related diseases. Preferred... Academisch Ziekenhuis Leiden H o d n Lumc

Cd94/nkg2a and/or cd94/nkg2b antibody, vaccine combinations

The disclosure provides among others a combination of a vaccine and a CD94/NKG2A and/or a CD94/NKG2B binding antibody for use in the treatment of a subject in need thereof, wherein said vaccine comprises an immunogen for eliciting an immune response against an antigen or a nucleic acid molecule encoding said... Academisch Ziekenhuis Leiden H o d n Lumc

Anti-carbamylated protein antibodies and the risk for arthritis

Antibodies against citrullinated protein antigens (ACPA) have shown their relevance for the diagnosis and possibly pathogenesis in arthritis. Described are means and methods for determining antibodies against homocitrulline-containing proteins or carbamylated proteins/peptides (anti-CarP) for the classification of individuals suffering from, or at risk of suffering from, arthritis.... Academisch Ziekenhuis Leiden H o d n Lumc

Antisense oligonucleotide directed removal of proteolytic cleavage sites, the hchwa-d mutation, and trinucleotide repeat expansions

Described are methods for removing a proteolytic cleavage site, the HCHWA-D mutation or the amino acids encoded by a trinucleotide repeat expansion from a protein comprising providing a cell that expresses pre-mRNA encoding the protein with an anti-sense oligonucleotide that induces skipping of the exonic sequence that comprises the proteolytic... Academisch Ziekenhuis Leiden H o d n Lumc

Antisense oligonucleotide directed removal of proteolytic cleavage sites from proteins

The invention relates to means and methods for removing a proteolytic cleavage site from a protein comprising providing a cell that expresses pre-mRNA encoding the protein with an anti-sense oligonucleotide that induces skipping of the exonic sequence that encodes the proteolytic cleavage site, the method further comprising allowing translation of... Academisch Ziekenhuis Leiden H o d n Lumc

Intradermal hpv peptide vaccination

The invention relates to the use of a peptide derived from HPV-E2, -E6 and/or E7 protein for the manufacture of a medicament for the treatment or prevention of an HPV related disease, wherein the medicament is for interdermal administration.... Academisch Ziekenhuis Leiden H o d n Lumc








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