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Acetylon Pharmaceuticals Inc patents


Recent patent applications related to Acetylon Pharmaceuticals Inc. Acetylon Pharmaceuticals Inc is listed as an Agent/Assignee. Note: Acetylon Pharmaceuticals Inc may have other listings under different names/spellings. We're not affiliated with Acetylon Pharmaceuticals Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Acetylon Pharmaceuticals Inc-related inventors


Phenyl and pyridinyl hydroxamic acids

The present invention relates to pyrimidine hydroxy amide compounds, the use of such compounds in the inhibition of hdac6, and the use of such compounds in the treatment of various diseases, disorders, or conditions related to hdac6.. . ... Acetylon Pharmaceuticals Inc

Methods of use and pharmaceutical combinations of histone deacetylase inhibitors and cd20 inhibitory antibodies

The disclosure relates to pharmaceutical combinations comprising an hdac6 selective inhibitor and a cd20 inhibitory antibody for the treatment of a b-cell disorder, such as cancer, in a subject in need thereof. Also provided herein are methods for treating a b-cell disorder in a subject in need thereof, comprising administering to the subject an effective amount of an hdac6 selective inhibitor and a cd20 inhibitory antibody.. ... Acetylon Pharmaceuticals Inc

Biomarkers to identify patients that will respond to treatment and treating such patients

The invention relates to methods for using biomarkers to identify cancer patients that will or are likely to respond to treatment. Specifically, the invention relates to the use of one or more of three association studies of cancer types, gene mutations, or gene expression levels in order to identify cancer patients that will or are likely to respond to treatment with a histone deacetylase (hdac) inhibitor, alone or in combination with another cancer treatment. ... Acetylon Pharmaceuticals Inc

Selective hdac3 inhibitors

Provided herein are hdac3 inhibitors, as well as methods of treatment comprising administering these compounds to a subject in need thereof.. . ... Acetylon Pharmaceuticals Inc

Hdac inhibitors for the treatment of diabetic peripheral neuropathy

The invention relates to hdac inhibitors for use in the treatment of diabetic peripheral neuropathy in a subject in need thereof. Also provided herein are methods for treating diabetic peripheral neuropathy in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an hdac inhibitor.. ... Acetylon Pharmaceuticals Inc

Pyrimidine hydroxy amide compounds as hdac6 selective inhibitors

The present invention relates to pyrimidine hydroxy amide compounds, the use of such compounds in the inhibition of hdac6, and the use of such compounds in the treatment of various diseases, disorders, or conditions related to hdac6.. . ... Acetylon Pharmaceuticals Inc

Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof

The present invention relates to novel pyrimidine hydroxy amide compounds, and the use of such compounds in the inhibition of hdac6 and in the treatment of various diseases, disorders or conditions related to hdac6.. . ... Acetylon Pharmaceuticals Inc

Selective hdac1 and hdac2 inhibitors

Provided herein are compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with hdac activity, particularly diseases or disorders that involve activity of hdac1 and/or hdac2. Such diseases include cancer, sickle-cell anemia, beta-thalassemia, and hiv.. ... Acetylon Pharmaceuticals Inc

Combinations of histone deacetylase inhibitors and either her2 inhibitors or pi3k inhibitors

The invention relates to combinations comprising an hdac inhibitor and a her2 inhibitor for the treatment of breast cancer in a subject in need thereof. The invention also relates to combinations comprising an hdac inhibitor and a pi3k inhibitor for the treatment of breast cancer in a subject in need thereof. ... Acetylon Pharmaceuticals Inc

Crystalline forms of a histone deacetylase inhibitor

This disclosure provides solid forms of 2-((2-chlorophenyl)(phenyl)amino)-n-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide, and methods of manufacturing and using these forms.. . ... Acetylon Pharmaceuticals Inc








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