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Adaptive Biotechnologies Corporation patents

Recent patent applications related to Adaptive Biotechnologies Corporation. Adaptive Biotechnologies Corporation is listed as an Agent/Assignee. Note: Adaptive Biotechnologies Corporation may have other listings under different names/spellings. We're not affiliated with Adaptive Biotechnologies Corporation, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Adaptive Biotechnologies Corporation-related inventors

Characterization of adaptive immune response to vaccination or infection using immunosequencing

Methods of monitoring and measuring dynamic adaptive immune cell responses are provided. High-throughput sequencing of T cell receptor and immunoglobulin loci is used to characterize the breadth of an effector cell response to a stimulus, such as a vaccine or infection. Unique responding effector cell clones and abundance thereof can... Adaptive Biotechnologies Corporation

Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from a large number of samples

The invention is directed to methods for highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune heterodimers from a large number of biological samples containing lymphocytes of interest. Methods of the invention comprise performing a single pairing assay on a pool of source samples to determine nucleic acids encoding... Adaptive Biotechnologies Corporation

Methods using randomer-containing synthetic molecules

Methods are provided for correction of amplification bias and quantitation of adaptive immune cells in a sample using synthetic templates that include random oligonucleotide sequences.... Adaptive Biotechnologies Corporation

T-cell receptor clonotypes shared among ankylosing spondylitis patients

The invention includes a method for determining the disease status of an individual suffering from ankylosing spondylitis by monitoring the individual's T-cell repertoire for the presence and/or level of clonotypes encoding T-cell receptor chains with segments identical to ant or related to the peptide LCASSLEASGSSYNEQFFGPGTRLTV (SEQ ID NO: 1) or... Adaptive Biotechnologies Corporation

Quantification of adaptive immune cell genomes in a complex mixture of cells

A relative representation of adaptive immune cells in a biological sample is quantified using multiplex PCR and sequencing of adaptive immune cells, control genes, and synthetic template molecules. Disclosed herein are methods for quantifying a number of adaptive immune cells in a biological sample, and methods for quantifying a relative... Adaptive Biotechnologies Corporation

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