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Affymetrix Inc patents


Recent patent applications related to Affymetrix Inc. Affymetrix Inc is listed as an Agent/Assignee. Note: Affymetrix Inc may have other listings under different names/spellings. We're not affiliated with Affymetrix Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Affymetrix Inc-related inventors


Methods and devices for reading microarrays

In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface... Affymetrix Inc

System, method, and computer software product for genotype determination using probe array data

An embodiment of a method of analyzing data from processed images of biological probe arrays is described that comprises receiving a plurality of files comprising a plurality of intensity values associated with a probe on a biological probe array; normalizing the intensity values in each of the data files; determining... Affymetrix Inc

Differential filtering of genetic data

Computer software products, methods, and systems are described which provide functionality to a user conducting experiments designed to detect and/or identify genetic sequences and other characteristics of a genetic sample, such as, for instance, gene copy number and aberrations thereof. The presently described software allows the user to interact with... Affymetrix Inc

Polyfluoreno[4,5-cde]oxepine conjugates and their use in methods of analyte detection

The invention provides for polyfluoreno[4,5-cde]oxepine conjugates and their use in methods of analyte detection.... Affymetrix Inc

Methods, systems and apparatuses for testing and calibrating fluorescent scanners

Disclosed are calibration apparatuses for fluorescent microscopy instruments and methods of making and using them. Specifically, disclosed are calibration apparatuses with a fluorescent layer, such as photoresist, deposited on a substrate, with an optional layer of a reflective material, such as chrome. Illumination of the fluorescent and/or reflective layers, and... Affymetrix Inc

Silane mixtures

Silanation compositions containing a mixture of two or more silanation reagents, where at least one silanation reagent includes a functional group capable of supporting polymer synthesis and at least one silanation reagent includes no functional group capable of supporting polymer synthesis are useful in modulating the active site density and... Affymetrix Inc

Methods of analysis of methylation

Methods for determining the methylation status of a plurality of cytosines are disclosed. In some aspects genomic DNA target sequences containing CpGs are targeted for analysis by multiplex amplification using target specific probes that can be specifically degraded prior to amplification. The targets may be modified with bisulfite prior to... Affymetrix Inc

Multiplex targeted amplification using flap nuclease

Methods for multiplex amplification of a plurality of targets of distinct sequence from a complex mixture are disclosed. In one aspect targets are circularized using a single circularization probe that is complementary to two regions in the target that flank a region to be amplified. The targets may hybridize to... Affymetrix Inc

Multiplex targeted amplification using flap nuclease

Methods for multiplex amplification of a plurality of targets of distinct sequence from a complex mixture are disclosed. In one aspect targets are circularized using a single circularization probe that is complementary to two regions in the target that flank a region to be amplified. The targets may hybridize to... Affymetrix Inc

Locus specific amplification using array probes

Methods are provided for multiplexed amplification of selected targets and analysis of the amplified targets. In preferred aspects the amplification and analysis take place on the same solid support and preferably in a localized area such as a bead or a feature of an array. In preferred aspects the analysis... Affymetrix Inc

Complexity management of genomic dna

The presently claimed invention provides for novel methods and kits for reducing the complexity of a nucleic acid sample by providing non-gel based methods for amplification of a subset of the sequences in a sample. In a preferred embodiment, amplification of a subset can be accomplished by digesting a sample... Affymetrix Inc








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