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Agency For Science Technology And Research patents


Recent patent applications related to Agency For Science Technology And Research. Agency For Science Technology And Research is listed as an Agent/Assignee. Note: Agency For Science Technology And Research may have other listings under different names/spellings. We're not affiliated with Agency For Science Technology And Research, we're just tracking patents.

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The synthesis of multiarm poly[(r)-3-hydroxybutyrate] and its derivatives

Provided herein is a polymer having formula I: where m, n, and R1 are as defined herein, and the polymer has a number average molecular weight of the polymer of from 500 to 80,000 Daltons. Also provided herein are block copolymers of the polymer of formula I, as well as... Agency For Science Technology And Research

Contractile cellular construct for cell culture

The present invention relates to a method for producing a contractile cellular construct, comprising the steps of: a) seeding pre-selected cells onto a mold, wherein the pre-selected cells comprise signal emitting agents; and b) culturing the pre-selected cells to produce the cellular construct. The said method is exemplified by mixing... Agency For Science Technology And Research

Dermatopontin as a therapeutic for metabolic disorders

The present disclosure describes to a method of treating a metabolic disease in a subject, wherein the method comprises administration of dermatopontin to a subject, wherein the dermatopontin is recombinant dermatopontin and the metabolic disease is selected from a group consisting of weight gain, diet-induced weight gain, obesity, morbid obesity,... Agency For Science Technology And Research

Compounds for the diagnosis or treatment of disorders associated with protein or peptide oligomers

The present invention relates to compounds of Formula (I) as defined herein as well as conjugates comprising said compounds and pharmaceutical compositions comprising said compounds or conjugates. Also encompassed are methods for selectively detecting oligomeric proteins or peptides associated with a conformational disorder in a sample, and methods for diagnosing... Agency For Science Technology And Research

Anti-reflection coating

This invention relates to a UV-curable coating material comprising an organosilica compound such as POSS or octahedral oligomeric silsesquioxane which is functionalized with a UV-curable functional group. The material further comprises at least one UV-curable cross-linker. The coating material comprises surface structures in the nano-sized range and can be used... Agency For Science Technology And Research

A composite laminate and its usage

The present invention relates to a laminate for making a molded article comprising: (i) at least one reinforcement Iayer impregnated with a resin matrix; (ii) at least one deployable layer; and (iii) optionally, at least one material comprising at least one non-adhesive side, wherein the deployable layer are compactable, expandable... Agency For Science Technology And Research

Non-membrane disruptive p53 activating stapled peptides

The present invention relates to non-membrane disruptive and p53 activating stapled peptides, as well as methods of treatment of cancer involving the use of these peptides. In one embodiment, the peptide comprises or consist of the amino acid sequence of TSFXaa1EYWXaa3LLXaa2, where Xaa1 is (R)-2-(7′-octenyl)alanine or derivative thereof, or is... Agency For Science Technology And Research

Self-assembling ultrashort aliphatic cyclic peptides for biomedical applications

The invention relates to cyclic peptides of 3-9 amino acids comprising 2-7 aliphatic and 0-2 polar amino acids that are capable of self-assembling, wherein said aliphatic amino acids are arranged in decreasing hydrophobicity from N- to C-terminus and at least a portion of the cyclic peptide has to have its... Agency For Science Technology And Research

A copolymer comprising a lignin or lignin derivative and a poly(alkylene oxide) alkyl ether (meth)acrylate, and a hydrogel comprising the copolymer

A copolymer comprising an oxygenated polyaromatic alcohol and a poly (alkylene oxide) alkyl ether (meth)acrylate is disclosed, wherein the oxygenated polyaromatic alcohol is preferably lignin or lignin derivative. A hydrogel comprising the copolymer and a cyclic oligosaccharide such as α-cyclodextrin is also disclosed, which can be used in biomedical or... Agency For Science Technology And Research

Self-aligning source, drain and gate process for iii-v nitride mishemts

A method for fabrication of high electron mobility transistor (HEMT) semiconductor devices is presented. The method includes providing a substrate, growing a HEMT layer structure on the substrate; and self-aligned common metal stack formation of source, drain and gate electrodes on the HEMT layer structure using a single lithographic mask.... Agency For Science Technology And Research

Current forming of resistive random access memory (rram) cell filament

A memory device includes a metal oxide material disposed between and in electrical contact with first and second conductive electrodes, and an electrical current source configured to apply one or more electrical current pulses through the metal oxide material. For each of the one or more electrical current pulses, an... Agency For Science Technology And Research

Development of abcg2-sensitive fluorescent probe for isolation of abcg2low neural stem/progenitor cells

The present invention relates to the synthesis and characterization of an Abcg2 targeted fluorescence probe (compound of formula I), as well as live imaging of neural stem/progenitor cells (NSPCs) and isolation of live NSPCs using said probe.... Agency For Science Technology And Research

Magnetoresistive device and forming the same

According to embodiments of the present invention, a magnetoresistive device is provided. The magnetoresistive device includes a free magnetic layer structure having a variable magnetization orientation, a fixed magnetic layer structure having a fixed magnetization orientation, and a tilting magnetic layer structure configured to provide an interlayer exchange biasing field... Agency For Science Technology And Research

P-type semiconducting polymers and related methods

There is provided p-type organic polymers of general formula I. The polymers may be useful as semi-conducting material. Thus, thin films and devices comprising such polymers are also provided.... Agency For Science Technology And Research

Self-assembling ultrashort aliphatic depsipeptides for biomedical applications

The present invention relates to ultrashort depsipeptides which are capable of self-assembling into hydrogels. One preferred embodiment is of Ac-ILVaGK-NH2, where a represents lactic acid. The invention also relates to the use of these depsipeptides in formulating hydrogels, co-gels or co-hydrogels, and pharmaceutical compositions or biomedical device or surgical implants... Agency For Science Technology And Research

Process for making an array

There is disclosed a method of making an array for cell assays comprising the step of providing an array of structures on a substrate, each of said structures having a pre-defined topography thereon, and wherein at least one structure has a different topography from at least one other structure.... Agency For Science Technology And Research

Device and energy harvesting using a self-oscillating power-on-reset start-up circuit with auto-disabling function

Device and method for energy harvesting using a self-oscillating power-on reset start-up circuit. The device for energy harvesting comprises a start-up circuit for generating self-oscillation and initial boosting of an input voltage from an energy source during a start-up phase; a main boost circuit for boosting the input voltage during... Agency For Science Technology And Research

Fillers for polymers

This invention relates to a composite material comprising a core comprising an organosilica such as a polyhedral oligomeric silsesquioxane (POSS) and a functionalized elastomeric polymer such as poly(n-butyl acrylate) bonded onto said core. The elastomer is preferably functionalised with an amine moiety. The present invention also relates to a polymer... Agency For Science Technology And Research

Nanocapsules carrying chikungunya-associated peptides

The present invention refers to a composition comprising a viral protein or fragment thereof, wherein the viral protein or fragment thereof is enclosed within a self-assembling protein nanocapsule, preferably ferritin, and wherein the viral protein, or fragment thereof is selected from a virus of the Togaviridae family. The viral protein... Agency For Science Technology And Research

Column-based device and retrieval of rare cells based on size, and uses thereof

A column-based device and method for retrieving cells of interest were enclosed. The said device comprises a column comprising (i) an inner wall defining an inner chamber with inlet and outlet openings, (ii) a perforated plug disposed adjacent to the outlet opening, (iii) a sleeve insert with a channel and... Agency For Science Technology And Research

Differentiation of macrophages from pluripotent stem cells

The present invention relates to a method of culturing primitive-like macrophages from stem cells, a kit when used in the method thereof and uses of the primitive like macrophage for in-vitro disease models and for screening compounds for therapy. One embodied culture method comprises contacting and incubating embryonic stem cells... Agency For Science Technology And Research

Memory cell selector and operating memory cell

Embodiments provide a selector device for selecting a memory cell. The selector device includes a first electrode; a second electrode; and a switching layer sandwiched between the first electrode and the second electrode. The switching layer includes at least one metal rich layer and at least one chalcogenide rich layer.... Agency For Science Technology And Research

Memory device and operating thereof

According to various embodiments, there is provided a memory device including at least one sense amplifier having a first side and a second side, wherein the second side opposes the first side; a first array including a plurality of memory cells arranged at the first side; a second array including... Agency For Science Technology And Research

Mobile manipulator and controlling the mobile manipulator for tracking a surface

There is provided a method of controlling a mobile manipulator for tracking a surface. The mobile manipulator includes a mobile base movable in an axial direction of the mobile manipulator and a manipulator supported on the mobile base having an end effector adjustable in a lateral direction of the mobile... Agency For Science Technology And Research

Method for synthesizing an alkenoic acid

There is provided a method for synthesizing an alkenoic acid, in particular acrylic acid comprising the step of oxidizing an alkenyl alcohol in the presence of a metal oxide catalyst to form the alkenoic acid. The invention further provides a step of deoxydehydrating a polyol, including glycerol to obtain said... Agency For Science Technology And Research

Anti-pd-l1 antibodies

Anti-PD-L1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and methods of using such antibodies to restore T-cell function in T-cells exhibiting T-cell exhaustion or T-cell anergy.... Agency For Science Technology And Research

Antenna structure for a radio frequency identification (rfid) reader, manufacturing thereof, rfid reader and rfid system

There is provided an antenna structure for a radio frequency identification (RFID) reader. The antenna structure includes a substrate, and an antenna structure disposed on the substrate. The antenna includes a peripheral frame portion, a first strip section disposed at a first side of the peripheral frame portion, and a... Agency For Science Technology And Research

Optical device and controlling the same

According to embodiments of the present invention, an optical device is provided. The optical device includes a waveguide structure including a floating gate, and an optical waveguide arranged spaced apart from the floating gate, wherein the optical waveguide overlaps with the floating gate, a carrier injection portion arranged spaced apart... Agency For Science Technology And Research

Methods for identifying clusters in a dataset, methods of analyzing cytometry data with the aid of a computer and methods of detecting cell sub-populations in a plurality of cells

According to various embodiments, there is provided a method for identifying clusters in a dataset, the method including: determining for each data point in the dataset, a plurality of parameters including a first parameter and a second parameter, the first parameter being a distance between the data point and a... Agency For Science Technology And Research

Sleep profiling system with feature generation and auto-mapping

A method for profiling sleep of an individual is provided. The method includes defining a sleep feature space for the individual, measuring a brain wave for the individual during the individual's sleep, and mapping the sleep feature space in response to a comparison of the brain wave and a previous... Agency For Science Technology And Research

Delayed-release particles

A delayed-release particle comprising a polymer-based matrix comprising polyvinylpyrrolidone and chitosan, and a hydrophobic benefit agent encapsulated by said polymer-based matrix; and processes and consumer products related thereto.... Agency For Science Technology And Research

Hydrophobic coatings (as amended)

A hydrophobic or superhydrophobic polymer composite comprising a lattice of poiycyclic aromatic hydrocarbons such as reduced graphene oxide (rGO) modified with at least one siloxane polymer and a method of preparation thereof is disclosed. A method of coating a material comprising immersing a material in a coating solution made from... Agency For Science Technology And Research

Method and aligning a two-dimensional image with a predefined axis

A method and apparatus for aligning a two-dimensional eye image with a predefined axis by rotation at a rotation angle are disclosed, the method comprising deriving the rotation angle and a de-noised image, which minimises a cost function comprising (i) a complexity measure of the de-noised image and (ii) magnitude... Agency For Science Technology And Research

Monoclonal antibody against muramyl peptides in prevention and treatment of immune-mediated diseases

Disclosed are methods of treating an autoimmune or inflammatory disease using a composition comprising an isolated antibody or an antigen-binding fragment or variant thereof that is capable of binding to muramyl peptide, derivative, analog or salt thereof, wherein said muramyl peptide comprises muramic acid and an amino acid selected from... Agency For Science Technology And Research

11/30/17 / #20170342373

Technique for formation and assembly of 3d cellular structures

In one example, the present invention refers to a method of making or producing a self-supporting cellular construct having a continuous channel within its central cavity, comprising the steps of providing a mould with a central opening, wherein the mould encloses a volume around the central opening (hole) capable of... Agency For Science Technology And Research

11/30/17 / #20170345871

Organic inverter and forming the same

Various embodiments provide a method of forming an organic inverter including a first transistor and a second transistor. The method may include providing a substrate with a dielectric layer formed on top of the substrate; depositing a first semiconductor polymer layer on a first region of the dielectric layer; forming... Agency For Science Technology And Research

11/23/17 / #20170334912

Purine diones as wnt pathway modulators

The invention relates to the use of compounds of general structure (I) in modulation of the Wnt pathway [Formula should be inserted here] wherein R1, R2, R3, R4 and R5 are each, independently, H or an alkyl group; D is selected from the group consisting of H, halogen, alkyl, cycloalkyl,... Agency For Science Technology And Research

11/16/17 / #20170326059

Cosmetic use of heparan sulphate

Affinity purification of fibroblast growth factor 2-binding heparan sulphate from porcine mucosa (HS8) is disclosed. Also disclosed is a process for the care of keratinous material(s), comprising the application or administration of HS8, or a composition comprising thereof, to keratinous material(s). The composition may be used to improve the condition... Agency For Science Technology And Research

11/16/17 / #20170327847

Mutants of the bacteriophage lambda integrase

The present invention refers to lambda integrases comprising at least one amino acid mutation at positions 43, 319 and 336 of the lambda integrase as set forth in SEQ ID NO: 1. The invention further refers to nucleic acid molecules comprising the nucleotide sequence encoding the mutant lambda integrase and... Agency For Science Technology And Research

11/16/17 / #20170328793

A sensing device, system and a manufacture thereof

A sensing device comprising a first array of electrodes encapsulated in a first elastomeric layer; a second array of electrodes encapsulated in a second elastomeric layer; a third elastomeric layer intermediate the first and second elastomeric layer and comprising an array of micro-structures, wherein said electrodes and elastomeric layers are... Agency For Science Technology And Research

11/16/17 / #20170328837

Sers-based analyte detection

The present invention relates to method detecting analytes by surface enhanced Raman spectroscopy (SERS), comprising contacting the analytes with at least one analyte binding molecule attached to a metal substrate surface that enhances Raman scattering via a Raman-active molecular linker; and detecting a surface enhanced Raman signal from said compound.... Agency For Science Technology And Research

11/09/17 / #20170319059

Speckle reduction in optical coherence tomography images

An optical coherence tomography (OCT) image composed of a plurality of A-scans of a structure is analysed by defining, for each A-scan, a set of neighbouring A-scans surrounding the A-slices scan. Following an optional de-noising step, the neighbouring A-scans are aligned in the imaging direction, then a matrix X is... Agency For Science Technology And Research

11/09/17 / #20170319615

Heparan sulphates for use in repair and/or regeneration of skin

Affinity purification of fibroblast growth factor 2-binding heparan sulphate from porcine mucosa (HS8) is disclosed. Also disclosed is the use of HS8 in repair and regeneration of the skin for treating wounds, burns, ulcers and other skin injuries.... Agency For Science Technology And Research

11/09/17 / #20170319690

Anti-pd-l1 antibodies

Anti-PD-L1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.... Agency For Science Technology And Research

11/09/17 / #20170319704

Block copolymers for therapeutic drug delivery

Amphiphilic block copolymers (BCPs) were prepared comprising a poly(ethylene oxide) block and a biodegradable polycarbonate block functionalized with disulfide groups and carboxylic acid groups. The BCPs form self-assembled micellar particles in aqueous solution that can be loaded with hydrophobic drugs for therapeutic drug delivery. The loaded particles have small particle... Agency For Science Technology And Research

11/09/17 / #20170321240

Glycosylation mutants for producing galactose-free and fucose-free polypeptides

We describe a method of reducing batch-to-batch variation or increasing homogeneity between batches in the production of a recombinantly expressed polypeptide. The method comprises expressing the polypeptide in a Chinese hamster ovary (CHO) cell comprising reduced UDP-galactose transporter activity compared to a wild-type CHO cell. In some embodiments, the CHO... Agency For Science Technology And Research

11/09/17 / #20170322217

A prognosis of ovarian cancer, patient's stratification

There are no reliable clinical bio-markers of survival prognosis, patient's risk stratification and treatment prediction for epithelial ovarian cancers(EOC). The most common type of the human EOC is a high grade serous EOC. This cancer is characterized with one of the lowest survival rates compared to other cancers. The present... Agency For Science Technology And Research

11/09/17 / #20170323452

Method and device for traffic sign recognition

Embodiments provide a method for recognizing a traffic sign from an input image. The method may include extracting image features from the input image; modifying the image features based on a predetermined image saliency map to determine modified image features; determining a plurality of traffic sign candidates by applying an... Agency For Science Technology And Research

11/02/17 / #20170312355

Clinical correlates of immunotherapy efficacy

A method for predicting whether a patient will be a long-term survivor on treatment of a disease by adoptive cell transfer (ACT), is disclosed comprising: (i) analysing a blood-derived sample obtained from the patient for one or more prognostic markers of long-term survival on treatment of a disease by ACT,... Agency For Science Technology And Research

11/02/17 / #20170313774

Anti-pd-1 antibodies

Anti-PD-1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.... Agency For Science Technology And Research

11/02/17 / #20170316823

Multi-step voltage for forming resistive random access memory (rram) cell filament

A memory device and method comprising a metal oxide material disposed between and in electrical contact with first and second conductive electrodes, and a voltage source configured to apply a plurality of voltage pulses spaced apart in time across the first and second electrodes. For each one of the voltage... Agency For Science Technology And Research

11/02/17 / #20170317471

An optical device and a fabricating thereof

According to various embodiments, there is provided an optical device including a first waveguide configured to guide a light wave along a longitudinal axis; a first grating at least partially formed in the first waveguide, the first grating arranged away from the longitudinal axis in a first direction; and a... Agency For Science Technology And Research

10/26/17 / #20170303541

Antimicrobial guanidinium and thiouronium functionalized polymers

Antimicrobial cationic polycarbonates and polyurethanes have been prepared comprising one or more pendent guanidinium and/or isothiouronium groups. Additionally, antimicrobial particles were prepared having a silica core linked to surface groups comprising a guanidinium and/or isothiouronium group. The cationic polymers and cationic particles can be potent antimicrobial agents against Gram-negative microbes,... Agency For Science Technology And Research

10/26/17 / #20170304369

Methods of differentiating stem cells into liver cell lineages

The present disclosure provides methods and kits for the differentiation of stem cells into relevant liver cell lineages, as well as methods of using the relevant liver cell lineages in screening for a cellular response, a phenotype and in the treatment of a condition. In one embodiment, stem cells are... Agency For Science Technology And Research

10/26/17 / #20170306016

Anti-tim-3 antibodies

Anti-TIM-3 antibodies are disclosed, as well as pharmaceutical compositions comprising such antibodies, and uses and methods using the same, such as in the treatment of cancer or infectious disease or T-cell dysfunctional disorders. Bispecific antibodies against TIM-3 and other targets are also disclosed, with a preferred embodiment of a bispecific... Agency For Science Technology And Research

10/26/17 / #20170307486

Apparatus for processing a sample in a liquid droplet and using the same

A device for processing a sample in a liquid droplet containing a hydrophilic liquid is described. The device includes: a circumferential wall and a base including an immobilisation member. The circumferential wall and the base define a reservoir adapted to accommodate a hydrophobic medium immiscible with the liquid droplet. The... Agency For Science Technology And Research

10/26/17 / #20170308523

A sentiment classification and emotion classification

A system and a method for classifying text messages, such as social media messages into sentiment valence categories are provided. The system comprising a module for decomposing text messages, a module for cleaning text messages, a module for producing feature data of text messages, and a module for classifying text... Agency For Science Technology And Research

10/26/17 / #20170309304

Hardware based crosstalk reduction for hard disk drives

An actuator assembly for crosstalk reduction in hard disk drives (HDDs) is provided. The actuator assembly comprises a base plate; a pivot; a voice coil motor (VCM) with an upper yoke and a lower yoke; and a cut-out insert having a predetermined stiffness and predetermined magnetic properties, wherein the cut-out... Agency For Science Technology And Research

10/26/17 / #20170309584

Method of bonding a first substrate and a second substrate

A method for bonding a first substrate and a second substrate, the first substrate having at least one first connection extending from one side of the first substrate, the method comprising fabricating a first adhesive material around and along a height of the at least one first connection; and bonding... Agency For Science Technology And Research

10/19/17 / #20170296081

Frame based spike detection module

A method and device for biomedical recording of biomedical spike signals is provided. The method includes extracting and aligning possible biomedical spike signals from received signals and, thereafter, performing spike detection by determining whether the possible biomedical spike signals are actual spike signals. The biomedical spike signals are preferably selected... Agency For Science Technology And Research

10/19/17 / #20170298039

Triphasic system for direct conversion of sugars to furandicarboxylic acid

There is provided a one-pot process for the conversion of sugars to furancarboxylic acids, such as 2,5-furancarboxylic acid (FDCA), in a triphasic system (e.g. water or tetraethylammonium bromide (TEAB)—methyl isobutyl ketone (MIBK)—water). In this reaction setup, sugars are first converted to 5-hydroxymethylfurfural (HMF) in a first phase. Then HMF is... Agency For Science Technology And Research

10/19/17 / #20170298522

Formulation and inhibiting carbon-based deposits

There is a formulation and a method for inhibiting carbon-based deposits on metal substrate. The method comprises the use of a formulation comprising at least one oxidizing agent and at least one etchant capable of forming free metal ions from the metal substrate, at least one sequestering agent having a... Agency For Science Technology And Research

10/12/17 / #20170291877

Antimicrobial imidazolium compounds

The present invention relates to antimicrobial imidazolium compounds having the structure of Formula (I) wherein R is an optionally substituted aliphatic group that is linear, cyclic, saturated, unsaturated or any combination thereof; n is an integer of at least 1; and X is an anionic counterion. The present invention also... Agency For Science Technology And Research

10/05/17 / #20170281662

Polycarbonates bearing aromatic n-heterocycles for drug delivery

Nanoparticles comprise a drug, a first block polymer and a second block polymer. The first block polymer has a poly(ethylene oxide) (PEO) block and a polycarbonate block bearing a side chain aromatic nitrogen-containing heterocycle (N-heterocycle). The N-heterocycle can be in the form of a base, a hydrosalt of the base,... Agency For Science Technology And Research

Patent Packs
10/05/17 / #20170282170

Phosphorus-containing catalysts

... Agency For Science Technology And Research

10/05/17 / #20170285021

A test strip for paper-based assay

This invention relates to a test strip for paper based assay, the test strip comprising a substrate addition zone for receiving a substrate and a test zone, the test zone comprising a capture agent, wherein the substrate addition zone is located upstream of the test zone. The invention 5 also... Agency For Science Technology And Research

10/05/17 / #20170285022

Test strip assembly

There is provided a test strip assembly for detecting the possible presence of at least one analyte in a sample, a device for detecting the possible presence of at least one analyte in a sample comprising the test strip assembly and methods of detecting the possible presence of at least... Agency For Science Technology And Research

10/05/17 / #20170285225

Molecular tunnel junctions and their use as sources of electronic plasmons

A method of producing electronic plasmons by applying a bias to a molecular tunnel junction to excite plasmons, in which the molecular tunnel junction contains a top metallic electrode formed of a eutectic metal alloy and a metal oxide, a bottom metallic electrode formed of a transition metal, and a... Agency For Science Technology And Research

09/28/17 / #20170273875

Core-shell particle

There is provided a core-shell particle comprising a polymer conjugate encapsulating an active agent, wherein the polymer conjugate comprises a biocompatible polymer and a polyacidic polymer. There is also provided a process for forming the core-shell particle, a delivery vehicle comprising the core-shell particle and a method for delivering an... Agency For Science Technology And Research

09/28/17 / #20170277447

Active storage devices

A printed circuit board assembly (PCBA) for a storage device comprising a non-volatile memory (NVM) and a multi-core processor, wherein a first core of the multi-core processor is devoted to external interface management and a second core of the multi-core processor is devoted to internal data management.... Agency For Science Technology And Research

09/28/17 / #20170277477

Distributed active hybrid storage system

An active storage system is disclosed. The active storage system includes a storage device, a non-volatile memory and an active drive controller. The active drive controller performs data management and/or cluster management within the active storage system, the active drive controller including a data interface for receiving at least object... Agency For Science Technology And Research

09/28/17 / #20170279040

Magnetic element and fabrication thereof

There is provided a magnetic element including a ferromagnetic reference layer having a fixed or pinned magnetization direction, a ferromagnetic free layer having a switchable magnetization direction based on spin transfer torque, an insulating spacer layer disposed between the ferromagnetic reference layer and the ferromagnetic free layer such that the... Agency For Science Technology And Research

09/28/17 / #20170279462

Method of constructing flat xor codes from integer indexed tanner graphs

A method for defining an erasure code for system having a predetermined number of data disks is disclosed. The method includes selecting step, constructing step, determining step and repeating step. The selecting step includes selecting a predetermined acceptable number of failures for the system. The constructing step includes constructing a... Agency For Science Technology And Research

09/21/17 / #20170266224

Cationic polyamines for treatment of viruses

Antiviral cationic polyamines were prepared by modifying polyethylenimines with N-acylating agents that introduce a side chain comprising one or more carbons and at least one alcohol hydroxy group. The cationic polyamines can have a linear or branched polyethylenimine backbone structure. Preferably, the cationic polyamines comprise pendant monosaccharide groups, which can... Agency For Science Technology And Research

09/21/17 / #20170270044

Active storage unit and array

An active storage unit and an active storage array are provided. The active storage unit includes an active control board having a processor, at least one internal memory module communicatively coupled to the processor, and a reconfigurable logic circuit communicatively coupled to the processor for programming the active storage unit.... Agency For Science Technology And Research

09/14/17 / #20170258757

Anti-cancer agent delivery vehicles capable of improved loading

There is provided a conjugate of a delivery agent containing a chemical moiety and at least one flavonoid. The flavonoid exists in a monomeric form or dimeric form before conjugation and remains in the monomeric form or dimeric form after conjugation. Preferably, the conjugate comprises two flavonoids. The delivery agent... Agency For Science Technology And Research

09/14/17 / #20170258845

Methods of treating graft versus host disease (gvhd) or epidermolysis bullosa (eb)

We describe the use of exosome such as mesenchymal stem cell exosomes in a method of promoting, restoring or enhancing homeostasis in an individual suffering from graft versus host disease (GVHD) or epidermolysis bullosa (EB). The homeostasis may comprise immune homeostasis such as maintenance of an immune response. The method... Agency For Science Technology And Research

09/14/17 / #20170258926

Micellar nanocomplex

The present invention relates to micellar nanocomplexes and a method of forming the same. The micellar nanocomplex comprises a micelle and an agent encapsulated within said micelle, where the micelle comprises a polymer-flavonoid conjugate, wherein said polymer is bonded to the B ring of said flavonoid. The micellar nanocomplex may... Agency For Science Technology And Research

09/14/17 / #20170259300

Amorphous metal oxide films

A method for preparing an amorphous metal oxide film is provided. The method comprises providing an aqueous composition comprising a metal fluorine compound; and contacting a substrate with the aqueous composition at a temperature of less than about 100° C. to obtain said amorphous metal oxide film on the substrate.... Agency For Science Technology And Research

Patent Packs
09/14/17 / #20170260259

Monoclonal antibody against muramyl peptides

Disclosed is an isolated antibody or an antigen-binding fragment thereof The antibody is capable of binding to a muramyl peptide, or a derivative or an analog or a salt thereof. The muramyl peptide comprises muramic acid and an amino acid selected from the group consisting of alanine, isoglutamine, glutamic acid,... Agency For Science Technology And Research

09/14/17 / #20170260503

Differentiation of hepatocyte-like cells from stem cells

Disclosed are methods of differentiating stem cells in order to obtain hepatocyte-like cells, the method comprising the steps of a) subjecting definitive endoderm to at least one epigenetic modulator to obtain hepatoblasts and b) subjecting the hepatoblasts to at least one stem cell differentiation pathway inhibitor to obtain hepatocyte-like cells;... Agency For Science Technology And Research

09/14/17 / #20170260526

Modified antimir-138 oligonucleotides

Disclosed is a modified oligonucleotide capable of reducing or inhibiting one or more activities miR-138. The modified oligonucleotide may comprise at least one locked nucleic acid (LNA) and wherein the oligonucleotide is substantially complementary to a nucleotide sequence of miR-138. Also disclosed are pharmaceutical compositions comprising the oligonucleotides, methods of... Agency For Science Technology And Research

08/24/17 / #20170238547

Antibacterial and/or antifouling polymers

The present disclosure provides a copolymer comprising monomer units represented by formulas (I) and/or (II) as disclosed and defined herein which are useful in antibacterial and/or antifouling coatings. The present disclosure further provides methods of synthesizing said copolymers.... Agency For Science Technology And Research

08/24/17 / #20170240424

Method of preparing a porous carbon material

A method of preparing a porous carbon material is provided. The method comprises a) freezing a liquid mixture comprising a polymer suspended or dissolved in a solvent to form a frozen mixture; b) removing the solvent from the frozen mixture to form a porous frozen mixture; and c) pyrolyzing the... Agency For Science Technology And Research

08/24/17 / #20170240633

Anti-tim-3 antibodies

Anti-TIM-3 antibodies are disclosed, as well as pharmaceutical compositions comprising such antibodies, and uses and methods using the same, such as in the treatment of cancer, infectious diseases, or T-cell dysfunctional disorders. Bispecific antibodies against TIM-3 and other targets are also disclosed, with preferred embodiment of a bispecific antibody against... Agency For Science Technology And Research

08/24/17 / #20170240635

Anti-pd-1 antibodies

Anti-PD-1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.... Agency For Science Technology And Research

08/24/17 / #20170243349

Automatic region-of-interest segmentation and registration of dynamic contrast-enhanced images of colorectal tumors

A method for dynamic contrast enhanced (DCE) image processing and kinetic modeling of an organ's region-of-interest is provided. The method includes deriving at least a contour of an exterior of the organ's region-of-interest from one or more of a plurality of images; generating a spline function in response to the... Agency For Science Technology And Research

08/24/17 / #20170243624

Flip-flop circuit, controlling a flip-flop circuit and memory device

According to embodiments of the present invention, a flip-flop circuit is provided. The flip-flop circuit includes a first stage circuit and a second stage circuit, wherein each of the first stage circuit and the second stage circuit is operable in two modes of operation, and a driver arrangement, wherein the... Agency For Science Technology And Research

08/17/17 / #20170233822

Microrna biomarker for the diagnosis of gastric cancer

Disclosed are methods of determining the likelihood of a subject having or developing a gastric cancer. The methods comprise measuring the expression level of at least one miRNA having at least 90% sequence identity with an miRNA as described herein in a non-cellular biofluid sample obtained from the subject, wherein... Agency For Science Technology And Research

08/17/17 / #20170234880

Diagnosis of cancer

The data provided herewith show that, biomarkers found within the cells of a tumor or cancer may also be present at adequate levels within the patient's urine to enable detection. Method of diagnosis, patient selection and treatment are provided, along with kits and devices.... Agency For Science Technology And Research

08/10/17 / #20170226211

Anti-ctla-4 antibodies

Anti-CTLA-4 antibodies are disclosed. Also disclosed are compositions comprising such antibodies, and uses and methods using the same.... Agency For Science Technology And Research

08/10/17 / #20170227456

Optical waveguide structure and optical gas sensor, and methods of fabrication thereof

There is provided an optical waveguide structure, including a substrate, an insulating layer disposed on the substrate whereby the insulating layer includes an air slot formed therein, a first material layer suspended over the air slot whereby the first material layer constitutes a waveguide core of the optical waveguide structure,... Agency For Science Technology And Research

08/03/17 / #20170216446

Polymer-flavonoid conjugate and uses thereof

There is provided a polymer-flavonoid conjugate, or a pharmaceutically acceptable salt thereof, uses thereof, and methods of making thereof. The disclosed polymer-flavonoid conjugates may be useful in the therapeutic and/or prophylactic treatment of a joint condition in a subject.... Agency For Science Technology And Research

08/03/17 / #20170217125

Electrospun conductive carbon fibers

A conductive carbonaceous fiber is provided, comprising a carbonaceous material obtained from carbonizing an electrospun fiber wherein said fiber comprises at least one conductive metal precursor. The electrospun fibers can be formed into fibrous mats during spinning, stabilization and carbonization that are conductive materials which can be used to make... Agency For Science Technology And Research

08/03/17 / #20170217853

Method and system for producing an olefin

There is provided a method for producing an optionally substituted olefin, comprising the steps of: dehydrogenating an optionally substituted alcohol in a first reaction zone comprising a first catalyst supported on a porous silica-based particle to form an optionally substituted carbonyl at a first set of reaction conditions; converting the... Agency For Science Technology And Research

08/03/17 / #20170218011

Purification of biological products by constrained cohydration chromatography

Materials and methods for use of constrained cohydration agents in the purification of biological materials such as antibodies, viruses, cells, and cellular organelles in connection with convective chromatography, fluidized bed or co-precipitation applications.... Agency For Science Technology And Research

08/03/17 / #20170218498

Process for depositing metal or metalloid chalcogenides

The instant invention provides a process for making metal or metalloid dichalcogenides from a metal or metalloid and elemental chalcogen using magnetron sputtering. The process may comprise the steps of directing sputtering gas ions at a metal or metalloid target, reacting the ejected metal or metalloid atoms from the target... Agency For Science Technology And Research

08/03/17 / #20170222030

Semiconductor device fabrication

There is provided a method for fabricating a semiconductor device having the following structure, and comprising the steps of growing a first and a second nucleation layer on a substrate; depositing a binary layer over these nucleation layers; and annealing the binary layer to form a first contact area and... Agency For Science Technology And Research

07/27/17 / #20170209530

Antibiotic compositions for treating bacterial infections

The present disclosure provides dry powder antibiotic compositions that are effective in the treatment of bacterial infections and associated conditions. Moreover, the present disclosure provides dry powder antibiotic compositions for the treatment of bacterial infections, by multi-drug resistant bacteria, resulting in the subsequent reduction in the prevalent rates of drug... Agency For Science Technology And Research

07/27/17 / #20170214392

Reference clock signal generators and methods for generating a reference clock signal

According to various embodiments, there is provided a method for generating a reference clock signal, the method including discharging a capacitive element to a discharged state, when a reset signal has a predetermined reset state; charging the capacitive element from the discharged state to a first voltage, when a charge... Agency For Science Technology And Research








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