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Agenovir Corporation patents


Recent patent applications related to Agenovir Corporation. Agenovir Corporation is listed as an Agent/Assignee. Note: Agenovir Corporation may have other listings under different names/spellings. We're not affiliated with Agenovir Corporation, we're just tracking patents.

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Antiviral nuclease methods

Methods and compositions treat a viral infection use a nuclease and an inhibitor that prevents dna repair, such as a crispr-associated nuclease and a small molecule that inhibits an enzyme of a repair pathway. Under guidance of a targeting sequence, the nuclease cuts viral nucleic acid without cutting the patient's genome. ... Agenovir Corporation

Oncoviral treatment with nuclease and chemotherapeutic

Compositions and methods for treating infection-associated cancer include the use of a nuclease that cuts nucleic acid of an oncovirus in combination with an adjunct chemotherapeutic that treats cancerous cells. For example, a cas9 endonuclease and a guide rna that matches a target in a viral genome without having any corresponding match in the human genome can be delivered along with an anti-apoptotic inhibitor.. ... Agenovir Corporation

Antiviral treatment with low immunogenicity

Compositions and methods are disclosed for reducing toxicity and immunogenicity of nucleases, especially when in use for cutting viral nucleic acids in host cells. Different nucleases that cut the same target are delivered at different times to avoid an immune response that interferes with a therapeutic effect of the nucleases.. ... Agenovir Corporation

Modified antiviral nuclease

A modified programmable nuclease provided as an antiviral therapeutic includes a programmable nuclease such as an rna-guided nuclease, a dna-guided nuclease, or a protein-guided nuclease linked to a secondary moiety to improve uptake, half-life, efficacy, or other properties. The nuclease is programmed to cleave viral genetic material in an infected patient.. ... Agenovir Corporation

Transgenic nuclease systems and methods

The invention provides transgenic organisms that include a transgene that codes for a product that can be used to digest foreign nucleic acid. The transgene can code for a targeting nuclease, a guide sequence, or other components of a guided nuclease system. ... Agenovir Corporation

Compositions and methods for treatment of latent viral infections

Methods for treating latent viral infections using a gene for a nuclease that is expressed in the presence of a latent viral infection, allowing the nuclease to digest viral nucleic acid. The gene is controlled by a switch that turns expression on in the presence of viral transcripts. ... Agenovir Corporation

Antiviral fusion proteins and genes

Viral infection is a persistent cause of human disease. Fusion polypeptide systems target the genomes of viral infections, rendering the viruses incapacitated.. ... Agenovir Corporation

Compositions and methods for latent viral transcription regulation

The invention provides compositions and methods that can be used to regulate viral transcription. Using a catalytically inactive nuclease such as deactivated cas9, or dcas9, a guide rna can be designed that recognizes a regulatory element within a viral nucleic acid. ... Agenovir Corporation

Delivery methods and compositions

The invention provides methods and compositions that remove target genetic material from a subject by delivery of an enzyme that degrades the target genetic material. The methods include delivering a composition of a nucleic acid to a tissue, such as skin, of a subject along with various types of energy to enhance permeability of the tissue and cause the nucleic acid to enter cells of the tissue, wherein the nucleic acid comprises a gene for an enzyme that cuts target genetic material. ... Agenovir Corporation








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