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Agenus Inc patents


Recent patent applications related to Agenus Inc. Agenus Inc is listed as an Agent/Assignee. Note: Agenus Inc may have other listings under different names/spellings. We're not affiliated with Agenus Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Agenus Inc-related inventors


Anti-lag-3 antibodies and methods of use thereof

The instant disclosure provides antibodies that specifically bind to lag-3 (e.g., human lag-3) and antagonize lag-3 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.. ... Agenus Inc

Class i mhc phosphopeptides for cancer immunotherapy and diagnosis

A set of phosphorylated peptides are presented by hla a*0101, a*0201, a*0301, b*4402, b*2705, b*1402, and b*0702 on the surface of melanoma cells. They have the potential to (a) stimulate an immune response to the cancer, (b) to function as immunotherapeutics in adoptive t-cell therapy or as a vaccine, (c) to facilitate antibody recognition of the tumor boundaries in surgical pathology samples, and (d) act as biomarkers for early detection of the disease. ... Agenus Inc

Anti-tim-3 antibodies and methods of use thereof

The instant disclosure provides antibodies that specifically bind to tim-3 (e.g., human tim-3) and antagonize tim-3 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.. ... Agenus Inc

Cell surface display, screening and production of proteins of interest

Aspects of the invention provide compositions and methods for displaying engineered polypeptides on a cell surface. According to aspects of the invention, immobilized polypeptides can be screened to identify one or more variants having one or more functional or structural properties of interest. ... Agenus Inc

Identification of antigen- or ligand-specific binding proteins

The present invention discloses novel methods for the generation, expression and screening of diverse collections of binding proteins such as antibodies or fragments thereof in vertebrate host cells in vitro, for the identification and isolation of ligand- or antigen-specific binding proteins. The methods disclosed herein allow the expression of diverse collections of binding proteins from at least one vector construct, which optionally can give rise to collections of diverse binding proteins upon transfer and expression into vertebrate host cells in situ.. ... Agenus Inc

Vaccine for treatment and prevention of herpes simplex virus infection

The present invention relates to methods and compositions for the prevention and treatment of herpes virus infections. The invention provides antigenic peptides, and pharmaceutical compositions comprising complexes of antigenic peptides and adjuvants that can activate an immune response against herpes viruses. ... Agenus Inc








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