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Applied Biosystems Llc
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Applied Biosystems Llc patents


Recent patent applications related to Applied Biosystems Llc. Applied Biosystems Llc is listed as an Agent/Assignee. Note: Applied Biosystems Llc may have other listings under different names/spellings. We're not affiliated with Applied Biosystems Llc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Applied Biosystems Llc-related inventors


Systems and methods for multiple analyte detection

Systems and methods for multiple analyte detection include a system for distribution of a biological sample that includes a substrate, wherein the substrate includes a plurality of sample chambers, a sample introduction channel for each sample chamber, and a venting channel for each sample chamber. The system may further include... Applied Biosystems Llc

Pna probes, probe sets, methods and kits pertaining to the detection of candida

This invention is related to novel PNA probes, probe sets, methods and kits pertaining to the detection of one or more species of Candida yeast. Non-limiting examples of probing nucleobase sequences that can be used for the probes of this invention can be selected from the group consisting of: AGA-GAG-CAG-CAT-GCA... Applied Biosystems Llc

Poly and copoly(n-vinylamide)s and their use in capillary electrophoresis

The invention relates generally to polymers and copolymers comprising N-vinylamide-type monomers, their preparation, and compositions, such as electrophoresis separation media, containing the same; to supports, such as capillaries, containing these polymers; and methods for separating a mixture of biomolecules, especially polynucleotides, using capillary electrophoresis. Separation media comprising such polymers yield... Applied Biosystems Llc

Methods, compositions, and kits comprising linker probes for quantifying polynucleotides

The present invention is directed to methods, reagents, kits, and compositions for identifying and quantifying target polynucleotide sequences. A linker probe comprising a 3′ target specific portion, a loop, and a stem is hybridized to a target polynucleotide and extended to form a reaction product that includes a reverse primer... Applied Biosystems Llc

Methods of detecting target nucleic acids

The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded... Applied Biosystems Llc

Signal noise reduction for imaging in biological analysis

A system and method for characterizing contributions to signal noise associated with charge-coupled devices adapted for use in biological analysis. Dark current contribution, readout offset contribution, photo response non-uniformity, and spurious charge contribution can be determined by the methods of the present teachings and used for signal correction by systems... Applied Biosystems Llc

Methods for placing, accepting, and filling orders for products and services

Methods and systems for ordering assays which detect SNPs or gene expression are provided. The methods use PCR and RT-PCR procedures. Collections of stock assays are assembled using pre- and post-manufacturing quality control procedures and made available to consumers via the Internet. In addition, custom assays are prepared upon order... Applied Biosystems Llc

High speed, high resolution compositions, methods and kits for capillary electrophoresis

The invention provides compositions, methods and kits for high speed, high resolution of analytes by capillary electrophoresis starting with uncoated capillaries. The compositions comprise a sieving component, comprising a non-crosslinked acrylamide polymer, and a surface interaction component, comprising at least one uncharged and non-crosslinked water-soluble silica-adsorbing polymer. Methods for employing... Applied Biosystems Llc

Multi-material microplate and method

A microplate assembly for performing an analytical method on an assay, comprising a microplate base structure having a plurality of apertures formed therethrough, and a plurality of well inserts coupled to the microplate base structure adjacent the apertures. Each of the plurality of well inserts has an open top portion... Applied Biosystems Llc

Crude biological derivatives competent for nucleic acid detection

The invention relates to methods for the detection of a specific sequence of RNA in a cell or tissue sample. The invention also relates to methods to enzymatically manipulate the RNA in a crude cell lysate in a number of applications.... Applied Biosystems Llc

Thermus scotoductus nucleic acid polymerases

The invention provides nucleic acids and polypeptides for a nucleic acid polymerase from a thermophilic organism, Thermus scotoductus. The invention also provides methods for using these nucleic acids and polypeptides.... Applied Biosystems Llc

Thermus brockianus nucleic acid polymerases

The invention provides nucleic acids and polypeptides for nucleic acid polymerases from a thermophilic organism, Thermus brockianus. The invention also provides methods for using these nucleic acids and polypeptides.... Applied Biosystems Llc

Nanowire-based system for analysis of nucleic acids

A method for sequencing a nucleic acid template includes forming a nanowire assembly including a semiconductor nanowire and a probe covalently bound to the semiconductor nanowire; contacting the nanowire assembly with a template nucleic acid; contacting the nucleic acid duplexes with an extension nucleic acid, the extension nucleic acid joined... Applied Biosystems Llc

Sequencing system with memory

The present teachings provide a device including a memory. According to various embodiments, the memory is readable, writable, and rewritable. The present teachings further provide processing stations, e.g., for carrying out electrophoresis, per, genetic analysis, sample preparation, and/or sample cleanup, etc., that are capable of reading from and/or writing/rewriting to... Applied Biosystems Llc

Reagents, kits and methods, for detecting biological molecules by energy transfer from an activated chemiluminescent substrate to an energy acceptor dye

Reagents, kits and methods for detecting biological molecules by energy transfer from an activated chemiluminescent substrate to an energy acceptor dye such as a J-aggregated dye are described.... Applied Biosystems Llc

Methods for multiplexing amplification reactions

A two-step multiplex amplification reaction includes a first step which truncates the standard initial multiplex amplification round to “boost” the sample copy number by only a 100-1000 fold increase in the target. Following the first step the product is divided into optimized secondary single amplification reactions, each containing one of... Applied Biosystems Llc

Methods and systems for using rfid in biological field

Biological reagent carrier devices and methods are disclosed, which employ RFID techniques to associate information with biological reagents.... Applied Biosystems Llc

Cooling in a thermal cycler using heat pipes

A device for amplifying a nucleic acid sample may include a sample holder configured to receive a nucleic acid sample, a heating system configured to raise the temperature of the sample, a cooling system configured to lower the temperature of the sample, and a controller configured to operably control the... Applied Biosystems Llc

Reagents, methods, and libraries for bead-based sequencing

The present invention provides methods for determining a nucleic acid sequence by performing successive cycles of duplex extension along a single stranded template. The cycles comprise steps of extension, ligation, and, preferably, cleavage. In certain embodiments the methods make use of extension probes containing phosphorothiolate linkages and employ agents appropriate... Applied Biosystems Llc

Information system for biological and life sciences research

An online life science research environment and virtual community with a focus on design and analysis of biological experiments includes a life sciences laboratory system employing at least one networked computer system that defines a virtual research environment. Users access the system through a portal associated with the networked computer... Applied Biosystems Llc

Method of making a paired tag library for nucleic acid sequencing

The present disclosure relates to methods and compositions for making paired tags and paired tag libraries.... Applied Biosystems Llc








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