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Astute Medical Inc patents


Recent patent applications related to Astute Medical Inc. Astute Medical Inc is listed as an Agent/Assignee. Note: Astute Medical Inc may have other listings under different names/spellings. We're not affiliated with Astute Medical Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Astute Medical Inc-related inventors


 new patent  Methods and compositions for diagnosis and prognosis of renal injury and renal failure

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more of follistatin-related protein 3, basigin, cathepsin b, and tenascin as diagnostic and prognostic bio-marker assays in renal injuries.. ... Astute Medical Inc

 new patent  Assays for timp2 having improved performance in biological samples

The invention provides timp2 immunoassays with improved clinical performance, particularly when used in the evaluation of renal injuries. The immunoassays rely on the selection and use of antibodies and antibody pairs that exhibit improved assay performance when used in complex clinical specimens such as biological fluids, and particularly when used in rapid assay formats such as lateral flow test devices.. ... Astute Medical Inc

Methods and compositions for diagnosis and prognosis of renal injury and renal failure

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more of insulin-like growth factor-binding protein 2, insulin-like growth factor-binding protein 3, insulinlike growth factor-binding protein 4, and insulin like growth factor-binding protein 6 as diagnostic and prognostic biomarker assays in renal injuries.. ... Astute Medical Inc

Methods for diagnosis and prognosis of renal injury and renal failure

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of proheparin-binding egf-like growth factor, tenascin c, angiopoietin-related protein 4, fibroblast growth factor 19, fibroblast growth factor 21, heparin-binding growth factor 1, angiopoietin-related protein 6, proepiregulin, probetacellulin, amphiregulin, angiogenin, thrombospondin-2, and collagen alpha-1(xviii) chain as diagnostic and prognostic biomarkers in renal injuries.. ... Astute Medical Inc

Assays for igfbp7 having improved performance in biological samples

The invention provides igfbp7 immunoassays with improved clinical performance, particularly when used in the evaluation of renal injuries. The immunoassays rely on the selection and use of antibodies and antibody pairs that exhibit improved assay performance when used in complex clinical specimens such as biological fluids, and particularly when used in rapid assay formats such as lateral flow test devices.. ... Astute Medical Inc

Methods and compositions for diagnosis and prognosis of stroke or other cerebral injury

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in stroke patients and in patients at risk for stroke. In particular, the invention relates to using assays that detect one or more biomarkers as diagnostic and prognostic biomarker assays in such patients.. ... Astute Medical Inc

Methods and compositions for diagnosis and prognosis of renal injury and renal failure

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect chitinase-3-like protein 1 as diagnostic and prognostic biomarker assays in renal injuries.. ... Astute Medical Inc

Blood biomarkers for appendicitis and diagnostics methods using biomarkers

The invention relates to methods and kits for diagnosing and/or treating appendicitis in a subject, comprising performing one or more assays configured to detect one or more biomarkers on a body fluid sample obtained from the subject to provide one or more assay result(s) and correlating the assay result(s) to the occurrence or nonoccurrence of appendicitis in the subject or likelihood of the future outcome to the subject.. . ... Astute Medical Inc

Methods and compositions for diagnosis and prognosis of renal injury and renal failure

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a plurality of assays, one or more of which is configured to detect a kidney injury marker selected from the group consisting of hyaluronic acid, immunoglobulin a, immunoglobulin g1, immunoglobulin g2, insulin-like growth factor-binding protein 7, alpha-1 antitrypsin, serum amyloid p component, metalloproteinase inhibitor 2, hepatocyte growth factor, intercellular adhesion molecule 1, beta-2-glycoprotein 1, interleukin-1 beta, neutrophil elastase, tumor necrosis factor receptor superfamily member 11b, interleukin-11, cathepsin d, c—c motif chemokine 24, c—x—c motif chemokine 6, c—c motif chemokine 13, c—x—c motif chemokines-1, -2, and -3, matrilysin, interleukin-2 receptor alpha chain, insulin-like growth factor-binding protein 3, and macrophage colony-stimulating factor 1 as diagnostic and prognostic biomarkers in renal injuries.. ... Astute Medical Inc

Methods and compositions for diagnosis and prognosis of renal injury and renal failure

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of stanniocalcin-1, antithrombin-iii, toll-like receptor 2, triiodothyronine (t3), thyroxine (t4), extracellular matrix protein 1, coagulation factor xiii a chain, coagulation factor xiii b chain, interleukin-17f, interleukin-22, vitronectin, progesterone, estradiol, growth/differentiation factor 15, and proprotein convertase subtilisin/kexin type 9 as diagnostic and prognostic biomarkers in renal injuries.. ... Astute Medical Inc

Methods and compositions for diagnosis and prognosis of renal injury and renal failure

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a measured urine concentration of one or more of timp2 and igfbp7 in combination with one or more of a measured serum creatinine and a measured urine output, which results are correlated to the renal status of the subject, and can be used for diagnosis, prognosis, risk stratification, staging, monitoring, categorizing and determination of further diagnosis and treatment regimens in subjects suffering or at risk of suffering from an injury to renal function, reduced renal function, and/or acute renal failure.. ... Astute Medical Inc

Methods and compositions for diagnosis and prognosis of renal injury and renal failure

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of tumor necrosis factor receptor superfamily member 8, alpha-fetoprotein, thyroxine-binding globulin, prostate-specific antigen (free form), apolipoprotein a, apolipoprotein e, thyrotropin subunit beta, platelet-derived growth factor b/b dimer, c—c motif chemokine 7, c—c motif chemokine 26, complement c4-b, corticotropin, interferon alpha-2, interleukin-4 receptor alpha chain, insulin-like growth factor-binding protein 4, insulin-like growth factor-binding protein 5, interleukin 21, interleukin 23 alpha subunit, interleukin-28a, interleukin-33, lutropin subunit beta, matrix metalloproteinase-1, neural cell adhesion molecule 1, pigment epithelium-derived factor, vascular endothelial growth factor receptor 2, vascular endothelial growth factor receptor 3, and igg4 as diagnostic and prognostic biomarkers in renal injuries.. ... Astute Medical Inc

Methods and compositions for diagnosis and prognosis of renal injury and renal failure

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of cancer antigen ca 15-3, c-c motif chemokine 18, c-c motif chemokine 24, cathepsin d, c-x-c motif chemokine 13, c-c motif chemokine 8, interleukin-2 receptor alpha chain, insulin-like growth factor-binding protein 3, interleukin-11, matrix metalloproteinase-8, transforming growth factor alpha, igg1, and igg2 as diagnostic and prognostic biomarkers in renal injuries.. ... Astute Medical Inc

Methods for evaluating renal injury and renal failure using urine levels of chitinase-3-like protein 1

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect chitinase-3-like protein 1 as a predictive biomarker in renal injuries.. ... Astute Medical Inc

08/31/17 / #20170248613

Methods and compositions for diagnosis and prognosis of renal injury and renal failure

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of thymic stromal lymphopoietin, vascular endothelial growth factor receptor 1, c-c motif chemokine 1, c-c motif chemokine 17, c-c motif chemokine 21, c-c motif chemokine 27, flt-3 ligand, immunoglobulin g subclass 3, interleukin-1 receptor type i, interleukin-20, interleukin-29, interleukin-7, platelet-derived growth factor a/b dimer, platelet-derived growth factor a/a dimer, and mmp9:timp2 complex as diagnostic and prognostic biomarkers in renal injuries.. ... Astute Medical Inc

08/17/17 / #20170234867

Quantitative lateral flow assay

The present invention relates to devices, kits, instruments and methods for quantitatively detecting multiple analytes in a sample. More specifically, the present invention relates to devices, kits, instruments and methods for quantitatively detecting multiple analytes with desired or targeted precision, and the uses thereof.. ... Astute Medical Inc

02/02/17 / #20170030927

Methods and compositions for diagnosis and prognosis of renal injury and renal failure

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of clusterin, heart-type fatty acid binding protein, hepatocyte growth factor, interferon gamma, interleukin-12 subunit beta, interleukin-16, interleukin-2, 72 kda type iv collagenase, matrix metalloproteinase-9, midkine, and serum amyloid p-component as diagnostic and prognostic biomarkers in renal injuries.. ... Astute Medical Inc

01/19/17 / #20170016917

Methods and compositions for diagnosis and prognosis of renal injury and renal failure

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of heat shock 70 kda protein 1, alpha-1-antitrypsin neutrophil elastase complex, stromelysin-1:metalloproteinase inhibitor 2 complex, 72 kda type iv collagenase:metalloproteinase inhibitor 2 complex, insulin-like growth factor 1 receptor, myeloid differentiation primary response protein myd88, neuronal cell adhesion molecule, and tumor necrosis factor ligand superfamily member 10 as diagnostic and prognostic biomarkers in renal injuries.. ... Astute Medical Inc








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