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Bayer Healthcare Llc patents


Recent patent applications related to Bayer Healthcare Llc. Bayer Healthcare Llc is listed as an Agent/Assignee. Note: Bayer Healthcare Llc may have other listings under different names/spellings. We're not affiliated with Bayer Healthcare Llc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "B" | Bayer Healthcare Llc-related inventors


Systemic treatment of blood-sucking and blood-consuming parasites by oral administration of a parasiticidal agent

Pharmaceutically acceptable single parasiticidal agent compositions of imidacloprid for oral delivery to mammals to systemically control targeted blood-sucking or blood-consuming parasites, such as fleas, ticks and certain species of helminthes and scabies.... Bayer Healthcare Llc

Contrast imaging agent with dissolved gas-evolving fluid

A diagnostic contrast composition includes a carrier fluid and a non-decaying gas-evolving fluid incorporated in the carrier fluid. The gas-evolving fluid has a vapor pressure sufficient to evolve the gas from a circulatory system within a lung of a patient. The gas-evolving fluid is a composition containing a sufficient quantity... Bayer Healthcare Llc

High pressure sensor for use with a fluid delivery system

A pressure sensor for use with a fluid delivery system having good sensitivity at low pressure, but also configured to remain in operating condition after being exposed to high pressures is disclosed herein. In one variation, the pressure sensor includes a fluid path set, a deformable element associated with the... Bayer Healthcare Llc

Antibody and protein formulations

Provided are salt-free antibody and other protein formulations that are substantially isosmotic and of low viscosity. Also provided are methods for the treatment of diseases using the disclosed formulations.... Bayer Healthcare Llc

Pharmaceutical composition for the treatment of cancer

The present invention pertains to a pharmaceutical composition comprising the compound of the formula (I) in a high concentration and at least one pharmaceutically acceptable excipient, the use of the composition for the treatment of hyper-proliforative diseases, such as cancer, either as a sole agent, or in combination with other... Bayer Healthcare Llc

Antibody and protein formulations

Provided are salt-free antibody and other protein formulations that are substantially isosmotic and of low viscosity. Also provided are methods for the treatment of diseases using the disclosed formulations.... Bayer Healthcare Llc

Multiple fluid delivery system with multi-use disposable set and features thereof

A multi-use disposable set (MUDS) has at least one syringe having a proximal end and a distal end spaced apart from the proximal end along a longitudinal axis. The MUDS further has a plunger reciprocally movable within a syringe interior between the proximal end and the distal end. A manifold... Bayer Healthcare Llc

Quick release plunger

A syringe system and components thereof are disclosed. The system may include a syringe body having a hollow lumen, a proximal open end, and a distal end. The syringe body may be configured to house a fluid therein. The syringe system may further include a plunger positioned in the hollow... Bayer Healthcare Llc

System and identifying a fill volume of a fluid chamber

A system and method for determining the fill volume of a fluid chamber includes a fluid injector, at least one fluid chamber in fluid communication with the fluid injector, one or more sensors positioned relative to the at least one fluid chamber and configured to detect a position of a... Bayer Healthcare Llc

Formulations and methods for increased recombinant protein production

Formulations and methods to increase the production of recombinant proteins, and other aspects, are disclosed. The formulations and methods relate to increasing mannose or calcium concentration, or both, in a cell culture medium formulation for culturing cells that express recombinant proteins. In some embodiments, a mammalian cell culture medium formulation... Bayer Healthcare Llc

Monoclonal antibodies against tissue factor pathway inhibitor (tfpi)

Isolated monoclonal antibodies that bind human tissue factor pathway inhibitor (TFPI) and the isolated nucleic acid molecules encoding them are provided. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided. Methods of producing the antibodies... Bayer Healthcare Llc

Self-orienting pressure jacket and pressure jacket-to-injector interface

A pressure jacket for use with a fluid injector includes a barrel having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end along a longitudinal axis. The pressure jacket includes at least one engagement member protruding from a terminal portion of... Bayer Healthcare Llc

Self-orienting pressure jacket and pressure jacket-to-injector interface

A pressure jacket includes a barrel having a proximal end, a distal end, and a sidewall extending substantially circumferentially between the proximal end and the distal end along a longitudinal axis. The pressure jacket also includes at least one retaining member having at least one first lug protruding radially outward... Bayer Healthcare Llc

Method of purifying and using 4-chloro-n-methy1-2-pyridinecarboxamide

The present invention relates to a process for preparing 4-(4-[({[4-chloro-3-(trifluoromethyl)-phenyl]amino}carbonyl)amino]-3-fluorophenoxy)-N-methylpyridine-2-carboxamide, its salts and monohydrate.... Bayer Healthcare Llc

Treatment of age related macular degeneration with a small active choroidal neovascularization lesion

Methods for treatment of wAMD with an active CNV lesion of less than 50% of the total lesion size and pharmaceutical compositions for the use therein are disclosed.... Bayer Healthcare Llc

Preform for blow molded syringe for use with injectors

A syringe for use in a pressurized injection of a fluid includes a syringe barrel including a polymeric material having undergone expansion via blow molding. A preform for blow molding a blow molded syringe is described, the preform including a proximal end having a retention mechanism adapted to connect to... Bayer Healthcare Llc

Self-orienting syringe and syringe interface

A medical injector including at least one syringe port for engaging at least one syringe and having a locking mechanism. The locking mechanism enables the syringe to self-align with the syringe port for locking engagement upon insertion of the syringe into the syringe port and to axially eject the syringe... Bayer Healthcare Llc

Devices and methods for occluding a fallopian tube

Devices and method for occluding a fallopian tube. The devices, in one embodiment, may include a plurality of expandable occluding members coupled by respective dissolvable connecting members.... Bayer Healthcare Llc

Gla domains as targeting agents

The disclosure relates to the recombinant Gla domain proteins and their use targeting phosphatidylserine (PtdS) moieties on the surface of cells, particularly those expressing elevated levels of PtdS, such as cells undergoing apoptosis.... Bayer Healthcare Llc

Selector valve for medical fluid delivery device

A selector valve for a medical fluid delivery device is disclosed. The valve includes a valve bore in fluid communication with an outlet channel, first and second outlet ports, and a selector valve body which includes a valve stem located within the valve bore and having a flow passage. The... Bayer Healthcare Llc

System and syringe fluid fill verification and image recognition of power injector system features

A fluid injection system and a fluid verification system for confirming that a syringe, containing a fluid for injection, is fully filled with fluid and neither has free space (i.e., air) near the distal end thereof when the syringe is provided in an upright position nor contains air bubbles. Imaging... Bayer Healthcare Llc

Factor viii glycoforms

The invention concerns glycosylated proteins having human factor VIII activity. In a preferred embodiment, the protein is glycosylated with oligosaccharides that include an alpha-(2,6)-linked sialic acid and a bisecting GlcNAc linked to a core beta-mannose.... Bayer Healthcare Llc

System and methods for pre-injection pressure prediction in injection procedures

A method of predicting peak pressure within a fluid path, which includes a tubing set and a catheter into which at least one fluid is introduced under pressure by a pressurizing system of a fluid injection apparatus, includes (a) inputting an initial injection protocol into the fluid injection apparatus according... Bayer Healthcare Llc

Generating a suitable model for estimating patient radiation does from medical imaging scans

Techniques are disclosed for estimating patient radiation exposure during computerized tomography (CT) scans. More specifically, embodiments of the invention provide efficient approaches for generating a suitable patient model used to make such an estimate, to approaches for estimating patient dose by interpolating the results of multiple simulations, and to approaches... Bayer Healthcare Llc

Front-loading medical injector adapted to releasably engage a syringe regardless of the orientation of the syringe with respect to the injector

A syringe for use with an injector includes a body having a rear end and a front end, a plunger movably disposed within the body, an attachment member associated with the body and adapted to releasably engage a syringe retaining mechanism of the injector regardless of the orientation of the... Bayer Healthcare Llc

Dose estimation service system configured to support multiple computerized medical imaging scan providers

Techniques are disclosed for estimating patient radiation exposure during computerized tomography (CT) scans. More specifically, embodiments of the invention provide efficient approaches for generating a suitable patient model used to make such an estimate, to approaches for estimating patient dose by interpolating the results of multiple simulations, and to approaches... Bayer Healthcare Llc

Compositions and methods for treatment with hemopexin

Compositions and methods are provided for therapeutic treatment using recombinant Hemopexin molecules having sufficient sialyation and/or absence of neutral glycans to allow for sufficient circulation to remove free heme from a biological organism. In other embodiments, a recombinant Hemopexin molecule is provided for therapeutic treatment having a percentage of neutral... Bayer Healthcare Llc

Fitment and container for powdered products, especially powdered products prone to clumping behavior

Fitment and container for powdered products, especially powdered products prone to clumping behavior, comprising a stopper that closes the passageway between the interior chamber and the mouth of the container, a pour spout in the stopper that permits the powdered product to flow through the passageway during a pouring operation,... Bayer Healthcare Llc

Compounded media powder formulation and preparation of liquid medium for cell culture

The present invention provides a compounded cell culture medium powder formulation comprising: a basal medium powder and a cell culture media supplement, wherein the cell culture media supplement comprises and one or more salts; one or more growth factors; one or more inorganic ions; an amino acid supplement comprising one... Bayer Healthcare Llc

Magnetic medical connector and fluid transfer set including the magnetic medical connector

A connector for a fluid path set for delivery of a fluid to a patient during a procedure is described. The connector includes a magnetic check valve for limiting fluid flow to one direction through the fluid path. The magnetic check valve is configured to open in response to one... Bayer Healthcare Llc

Combined radiopharmaceutical imaging system

An integrated radiopharmaceutical patient treatment system includes a portable radioisotope generation module configured to generate a gaseous radioisotope, a radiopharmaceutical processing module configured to dissolve the radioisotope in an injectable medical fluid, a fluid injection system in fluid communication with the radiopharmaceutical processing module and configured to inject a dose... Bayer Healthcare Llc

Treatment of cancers having resistance to chemotherapeutic agents

Any cancer can be treated, including cancers that have acquired resistance to another therapeutic agent, such as kinase inhibitors. DAST can also be used to treat cancers which have become refractory to other chemotherapeutic agents... Bayer Healthcare Llc

Occlusion implant

Contraceptive and/or sterilization methods and devices are disclosed which may improve the speed of tubal occlusion and mechanisms for anchoring for a contraceptive device. In accordance with some embodiments, improvements may be made to the delivery catheter to induce trauma and create faster tubal occlusion, improvements may be made to... Bayer Healthcare Llc

Treatment of cancers with acquired resistance to kit inhibitors

The present invention provides compositions and methods for treating cancers which have acquired resistance to a KIT inhibitor by administering effective amounts of DAST.... Bayer Healthcare Llc

06/15/17 / #20170165427

Syringe and fluid injection system with an orientation independent identification code

A syringe is provided including an orientation independent indicia that can be used to validate and determine information about the syringe, injection parameters, and/or fluid contained therein. The syringe includes a syringe barrel and an indicia located on a portion of the syringe containing or associated with identifying information about... Bayer Healthcare Llc

06/15/17 / #20170165243

Pharmaceutical compositions for the treatment of hyper-proliferative disorders

This invention relates to novel pharmaceutical compositions comprising a solid dispersion of the compound of Formula I below, to processes for preparing these novel pharmaceutical compositions and to their use for treating hyper-proliferative disorders, such as cancer, either as a sole agent or in combination with other therapies. Formula I... Bayer Healthcare Llc

06/01/17 / #20170154162

Systems and methods for managing adverse reactions in contrast media-based medical procedures

Described is a method of managing adverse reactions that may occur during a medical procedure that involves the administration of contrast media. The method includes acquiring, by a data acquisition unit, information about a patient and an upcoming medical procedure that involves the administration of contrast media, computing in advance... Bayer Healthcare Llc

05/25/17 / #20170143894

Inline patency check device

A fluid path set for use with an injection device has a single-patient disposable set and a patency check device. A proximal end of the single-patient disposable set is configured for connecting with the injection device. The patency check device has a proximal end configured for connecting with a distal... Bayer Healthcare Llc

05/18/17 / #20170136424

Fluid path set with turbulent mixing chamber, back flow compensator

A fluid path set includes a first fluid line having a proximal end fluidly connectable to a source of a first fluid and a second fluid line having a proximal end fluidly connectable to a source of a second fluid. A flow mixing device is in fluid communication with distal... Bayer Healthcare Llc

05/11/17 / #20170128257

Hydration prevention coating

Occlusion devices and delivery systems are described in which a polymerizing oil is used to protect a hydrogel from premature swelling. In an embodiment, a delivery system includes an occlusion device releasably coupled within a catheter sheath. The occlusion device includes an expandable implant and a hydrogel. An at least... Bayer Healthcare Llc

05/04/17 / #20170119962

Syringe identification using photochromic ink

A system for reading identifying information regarding a syringe assembly provided in a fluid injector is provided, the system including at least one syringe assembly having a syringe barrel with a distal end having a nozzle for expelling fluid therefrom and an open proximal end, the syringe barrel defining an... Bayer Healthcare Llc

05/04/17 / #20170119963

System and syringe plunger engagement with an injector

A plunger for use with a syringe has a plunger body with a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a plunger longitudinal axis. The plunger further has at least one resiliently deflectable retaining member having a first... Bayer Healthcare Llc

05/04/17 / #20170123074

Generating an estimate of patient radiation dose from medical imaging scans

Techniques are disclosed for estimating patient radiation exposure during computerized tomography (CT) scans. More specifically, embodiments of the invention provide efficient approaches for generating a suitable patient model used to make such an estimate, to approaches for estimating patient dose by interpolating the results of multiple simulations, and to approaches... Bayer Healthcare Llc

04/27/17 / #20170112995

Tubing assembly

A tubing assembly for use with a fluid delivery system has a first fluid line having a distal end and a proximal end for connecting to a first fluid source, and a second fluid line having a distal end and a proximal end for connecting to a second fluid source.... Bayer Healthcare Llc

04/27/17 / #20170113004

Syringe drip guard

A syringe assembly may include a syringe having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end, and a syringe drip guard extending around at least a circumferential portion of the sidewall between the distal end and the proximal end of... Bayer Healthcare Llc

04/27/17 / #20170115156

Syringe with indicator float

A syringe assembly may include a syringe having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end and defining an interior volume; and an indicator float provided in the interior volume of the syringe. The indicator float may be buoyant such... Bayer Healthcare Llc

04/20/17 / #20170107298

Monoclonal antibodies against tissue factor pathway inhibitor (tfpi)

Isolated monoclonal antibodies that bind to specific epitopes of human tissue factor pathway inhibitor (TFPI) and the isolated nucleic acid molecules encoding them are provided. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided.... Bayer Healthcare Llc

04/13/17 / #20170100577

Flow based pressure isolation and fluid delivery system including flow based pressure isolation and flow initiating mechanism

The fluid delivery system includes a pressurizing device for delivering a pressurized injection fluid, a low pressure fluid delivery system, and a pressure isolation mechanism adapted for fluid communication with the pressurizing device and low pressure fluid delivery system. The pressure isolation mechanism includes a housing defining an inlet port,... Bayer Healthcare Llc

03/30/17 / #20170087303

Medical fluid injector

Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or... Bayer Healthcare Llc

03/23/17 / #20170080148

System for syringe engagement to an injector

An injector system for injecting fluid includes a syringe and an injector. The syringe includes a body and a plunger movably disposed within the body. The plunger has at least one flexible leg extending toward the rearward end of the body. The injector has a housing with a front plate,... Bayer Healthcare Llc

03/16/17 / #20170072131

High pressure sensor for use with a fluid delivery system

A pressure sensor for use with a fluid delivery system having good sensitivity at low pressure, but also configured to remain in operating condition after being exposed to high pressures is disclosed herein. In one variation, the pressure sensor includes a fluid path set, a deformable element associated with the... Bayer Healthcare Llc

03/09/17 / #20170065763

Universal adapter for a medical injector and syringe identification system

A universal adapter for connecting a syringe to an injector is provided. The universal adapter for connecting a syringe to an injector includes: a body having a proximal end configured to connect to an injector; at least one radial support connected to the body and biased in an inward direction;... Bayer Healthcare Llc

03/09/17 / #20170065770

Bladder syringe fluid delivery system

A bladder syringe for a fluid delivery system includes a cylindrical body, a cap-bladder assembly, a plunger element disposed in the cylindrical body, and a mounting assembly to secure the cap-bladder assembly to the cylindrical body. The cylindrical body has a distal end and a proximal end and defines a... Bayer Healthcare Llc

03/02/17 / #20170056603

System and syringe fluid fill verification and image recognition of power injector system features

A fluid injection system and a fluid verification system for confirming that a syringe, containing a fluid for injection, is fully filled with fluid and neither has free space (i.e., air) near the distal end thereof when the syringe is provided in an upright position nor contains air bubbles. Imaging... Bayer Healthcare Llc

03/02/17 / #20170056604

System and syringe fluid fill verification and image recognition of power injector system features

A fluid injection system and a fluid verification system for confirming that a syringe, containing a fluid for injection, is fully filled with fluid and neither has free space (i.e., air) near the distal end thereof when the syringe is provided in an upright position nor contains air bubbles. Imaging... Bayer Healthcare Llc

02/23/17 / #20170049955

Multi-dose disposable system

A multi-dose disposable fluid delivery system includes at least one fluid container, a multi-use fluid path set, and a plurality of single-use fluid path sets. The at least one fluid container has a connection port configured for fluidly connecting with a first end of the multi-use fluid path set. The... Bayer Healthcare Llc

02/23/17 / #20170051042

Targeted coagulation factors and using the same

Targeted coagulation factors comprising a coagulation factor linked with at least one domain that specifically binds to a membrane protein on a blood cell is provided. The disclosed targeted coagulation factors increase the efficiency of coagulation factors and prolong their duration of action and thus, are an improvement for the... Bayer Healthcare Llc

02/16/17 / #20170043082

Medical injector system

A syringe includes a body and a plunger movably disposed within the body. The syringe may be used with an injector including a drive member. The drive member preferably includes at least one pin adapted to form a retractable abutting connection with an interior of a plunger to enable the... Bayer Healthcare Llc

02/16/17 / #20170043083

Pumping devices, use with medical fluids including compensation for variations in pressure or flow rate

A system for delivery of a medical fluid to a patient includes a pump system including a pressurizing unit to pressurize the medical fluid and a drive system in operative connection with the pressurizing unit. The pump system exhibits variation in pressure during operation. The system further includes a compensating... Bayer Healthcare Llc

02/09/17 / #20170035959

Multi-fluid medical injector system and methods of operation

A multi-fluid injector system and methods of operation thereof are presented. One embodiment of such a fluid injector system includes an automatic refill procedure for a fluid injector system comprising a fluid injector and an operably engaged syringe. The procedure includes the step of determining, using an electronic control device... Bayer Healthcare Llc

02/09/17 / #20170035974

Syringe with rolling diaphragm

A syringe for a fluid delivery system includes a pressure jacket having a distal end, a proximal end, and a throughbore therebetween. The syringe further includes a rolling diaphragm having a proximal end with an end wall for engaging a plunger, a distal end received within the throughbore of the... Bayer Healthcare Llc

02/02/17 / #20170027477

Method, apparatus, and computer-readable medium for generating a set of recommended orthotic products

In an embodiment, the present invention is an apparatus, comprising: a foot mat; a depth sensing camera; an elevated foot platform that reduces or prevents rotational movement of a foot; a processor in communication with the depth sensing camera, the processor further configured to calculate the circumference of a user's... Bayer Healthcare Llc

02/02/17 / #20170027539

System and method to achieve rapid quantitative dynamic molecular imaging scans

Methods and systems for controlled administration of a tracer and quantification of uptake of the tracer by a target organ are described. The method includes administering a tracer to a patient and imaging at least two regions of the patient's body that cannot be imaged simultaneously. An input function for... Bayer Healthcare Llc

02/02/17 / #20170027740

Contraceptive devices and methods

Contraceptive devices that provide substantially immediate and permanent sterilization are described herein. Systems and methods for transcervically delivering the contraceptive devices are also described herein. The contraceptive device may include an expandable implant. The implant includes hydrogel to provide substantially immediate sterilization, and tissue in-growth fibers to provide permanent sterilization.... Bayer Healthcare Llc

Patent Packs
01/26/17 / #20170021193

System and planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors

A method for planning and monitoring radiopharmaceutical usage during a plurality of radiopharmaceutical injection procedures includes: providing a schedule of the plurality of radiopharmaceutical injection procedures to produce a planned patient schedule; based on the planned patient schedule, calculating a multi-dose container configuration for use during the plurality of radiopharmaceutical... Bayer Healthcare Llc

01/19/17 / #20170014568

Fluid delivery system and fluid delivery to a patient

A fluid delivery system includes a pressurizing mechanism. The pressurizing mechanism includes: a substantially cylindrical body having a movable member positioned therein that divides the body into a first chamber and a second chamber; a plunger rod connected to a first side of the movable member and extending through a... Bayer Healthcare Llc

01/12/17 / #20170008965

Anti-prolactin receptor antibody formulations

Provided are a wide concentration range, especially high concentration, substantially salt-free anti-prolactin receptor antibody formulations that are substantially isosmotic and of low viscosity.... Bayer Healthcare Llc








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