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Baylor Research Institute patents


Recent patent applications related to Baylor Research Institute. Baylor Research Institute is listed as an Agent/Assignee. Note: Baylor Research Institute may have other listings under different names/spellings. We're not affiliated with Baylor Research Institute, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "B" | Baylor Research Institute-related inventors


Methods and compositions for treating pancreatitis

It was discovered that nf-κb signaling pathway plays a central role in pancreatitis, and inhibition of nf-κb signaling has the potential to reduce the incidence of pancreatitis and protect pancreatic tissues from inflammatory damage. Aspects of the disclosure relate to a method for inhibiting or treating pancreatitis in a subject in need thereof comprising administering a therapeutically effective amount of an nf-κb signaling pathway inhibitor to the subject.. ... Baylor Research Institute

Antigen presenting cell targeted vaccines

The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccines and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-cd40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-cd40 antibody or fragments thereof, including humanized antibodies.. ... Baylor Research Institute

Ulcerative colitis (uc)-associated colorectal neoplasia markers

Embodiments provide methods and compositions related to detecting neoplasia in ulcerative colitis patients by detection and analysis of the methylation state of mir-1, -9, -124, mir-137 and/or mir-34b/c in samples from uc patients.. . ... Baylor Research Institute

Antagonistic anti-ox40l antibodies and methods of their use

Described herein are methods and compositions for treating autoimmunity and inflammatory conditions without non-specific suppression of the host immune system. In particular, the anti-ox40l antibodies described herein are unique in that they not only inhibit the differentiation of inflammatory t cells but also promote the generation and function of regulatory t cells by inducing il-10 and inhibiting tnf-α and by reducing aberrant th2 cell responses. ... Baylor Research Institute

Fatty acid treatment for cardiac patients

A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase i, carnitine palmitoyltransferase ii, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial β-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof.. ... Baylor Research Institute

Compositions and methods for the systemic treatment of arthritis

The present invention includes compositions and methods for treating arthritic joints found in patients with autoinflammation, e.g., systemic onset juvenile idiopathic arthritis, by administering at the site of inflammation a therapeutically effective amount of at least one agent that reduces or blocks the bioavailability of interleukin-1β.. . ... Baylor Research Institute

Systems and methods for virtual learning environments

Systems and methods for virtual learning environments, such as those, for example, configured to assist in evaluating a user, including the competency of a user, in a field of interest.. . ... Baylor Research Institute

Glycogen or polysaccharide storage disease treatment method

A method for treating glycogen storage disease by administering an effective amount of a composition that includes ketogenic odd carbon fatty acids that ameliorate the symptoms of these diseases.. . ... Baylor Research Institute

Anti-cd40 antibodies and uses thereof

The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccine and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-cd40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-cd40 antibody or fragments thereof, including humanized antibodies.. ... Baylor Research Institute

Methods and compositions for treating autoimmune and inflammatory conditions

Described herein are compositions and methods for inhibiting an inflammatory or autoimmune response and for inducing immune tolerance in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an antigen presenting cell (apc)-targeted antibody operatively linked to il-10 or a fragment thereof. The compositions and methods described herein are useful for treating inflammatory and autoimmune disorders.. ... Baylor Research Institute

Methods and compositions for treating allergy and inflammatory diseases

Described herein are therapeutic approaches with immune modifiers of the th2 pathway for the treatment of allergic and inflammatory diseases. Aspects of the disclosure relate to methods for decreasing th2-type cell responses in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an anti-dectin-1 antibody or antigen binding fragment thereof operatively linked to a tlr agonist.. ... Baylor Research Institute

Mir-320e and colorectal cancer

Embodiments provide methods and compositions related to determining treatments for colorectal cancer patients by detection and analysis of the expression level of mirna such as mir-320e in the patients. Embodiments provide predictive, prognostic and/or diagnostics methods by identifying mirnas that are useful for clinical management of cancer patients, particularly colorectal cancer patients or patients at risk or determined to have colorectal cancer. ... Baylor Research Institute








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