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Brown University patents


Recent patent applications related to Brown University. Brown University is listed as an Agent/Assignee. Note: Brown University may have other listings under different names/spellings. We're not affiliated with Brown University, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "B" | Brown University-related inventors


 new patent  Minimally-invasive and activity-dependent control of excitable cells

The present invention provides a method of bioluminescence-driven optogenetic control of excitable cells. The excitable cell expresses a light-gated ion channel, and a luminescent protein can be expressed either in the excitable cell or in another cell proximal to the excitable cell. The methods of the invention can be used... Brown University

Optogenetic control of endothelial cells

The invention features methods for regulating vascular properties by controlling the membrane properties of endothelial cells using optogenetics and light. The invention features methods to transport therapeutics across the vascular barrier into tissues such as the brain and the lung, with high spatial and temporal precision, and for controlling vascular... Brown University

Patient reminder incentive spirometer utilization

A system and method for configuring and/or utilizing an incentive spirometer to interact with a user during a series of sessions, the incentive spirometer having a piston that is movable within a chamber by user inhalation. A sensor is mounted to detect movement of the piston, a perceptible prompt to... Brown University

Method and creating coherent bundle of scintillating fibers

A method and apparatus to manufacture a coherent bundle of scintillating fibers is disclosed. A method includes providing a collimated bundle having a glass preform with capillaries therethrough known in the industry as a glass capillary array, and infusing the glass capillary array with a scintillating polymer or a polymer... Brown University

Method of making coated substrates

Methods' and compositions for making coated substrates using a co-solvent method are disclosed. Embodiments of the present disclosure relate in general to methods and compositions for making thin films of organometallic halides. According to one aspect, organometallic halides are deposited from solution on the surface of a substrate at temperatures... Brown University

Beta tungsten thin films with giant spin hall effect for use in compositions and structures with perpendicular magnetic anisotropy

Methods, devices, and compositions for use with spintronic devices such as magnetic random access memory (MRAM) and spin-logic devices are provided. Methods include manipulating magnetization states in spintronic devices and making a structure using spin transfer torque to induce magnetization reversal. A device described herein manipulates magnetization states in spintronic... Brown University

System and simulating realistic clothing

A system generates a clothing deformation model which models one or more of a pose-dependent clothing shape variation which is induced by underlying body pose parameters, a pose-independent clothing shape variation which is induced by clothing size and underlying body shape parameters and a clothing shape variation including a combination... Brown University

Heat diffusion based genetic network analysis

Methods and devices are provided for performing heat diffusion based genetic analysis. A network comprising a plurality of genes is defined an initial heat score is assigned to each of the plurality of genes. A threshold value for evaluating whether heat will be diffused from each of the plurality of... Brown University

Compositions for stabilizing and delivering proteins

Compositions for stabilizing and delivering proteins and/or other bioactive agents are disclosed. The bioactive agents are embedded or encapsulated in a crystalline matrix. Typically the bioactive agents are in the form of micro- or nanoparticles. The crystalline matrix confers enhanced stability to the agents embedded therein relative to other microparticulate... Brown University

Virtual reality methods and systems

Some aspects include a virtual reality device configured to present to a user a virtual environment. The virtual reality device comprises a tracking device including at least one camera to acquire image data, the tracking device, when worn by the user, configured to determine a position associated with the user... Brown University

Methods for producing perovskite halide films

An aspect of the present disclosure is a method that includes exchanging at least a portion of a first cation of a perovskite solid with a second cation, where the exchanging is performed by exposing the perovskite solid to a precursor of the second cation, such that the precursor of... Brown University

Enhancement of skeletal muscle stem cell engraftment by dual delivery of vegf and igf-1

An improved device and method for extended repair and regeneration of muscle tissue. An exemplary device comprises (a) a scaffold comprising an ECM component; (b) a combination of growth factors such as VEGF and IGF; and (c) a population of myogenic cells. Implantation of the device leads to muscle regeneration... Brown University

Optical system and methods for the determination of stress in a substrate

Methods and systems are disclosed for measuring multidimensional stress characteristics in a substrate. Generally, the methods include applying a sequence of optical pump pulses to the substrate. The optical pump pulses induce a propagating strain pulse in the substrate. Optical probe pulses are also applied. By analyzing transient optical responses... Brown University

Thermal accelerant compositions and methods of use

A thermal accelerant is delivered to a tissue site and localized to modulate the shape, extent or other characteristic of RF or microwave-induced hyperthermic tissue ablation. The accelerant may be provided via an image-guided hand piece or via a lumen added to a microwave antenna, and promotes faster heating, more... Brown University

Method and creating coherent bundle of scintillating fibers

A method and apparatus to manufacture a coherent bundle of scintillating fibers is disclosed. In the method and apparatus, a polymer matrix of a transparent polymer and nanoparticle scintillators is placed on top of a collimated bundle having a plurality of capillaries and pressed in a pressure vessel until the... Brown University

Apparatus and passively cooling an interior

A system passively cools, regulates humidity and/or rectifies diffusive transport of water vapor in an interior area within a structure. The system includes a membrane assembly covering a portion of the structure, wherein the membrane has an interior side facing the interior area and an exterior side. The membrane assembly... Brown University

Methods for the diagnosis and treatment of pulmonary fibrosis in subjects with hermansky pudlak syndrome

Described herein are methods, assays, and systems related to the prognosis, diagnosis, and treatment of Hermansky Pudlak Syndrome (HPS) and, e.g., pulmonary fibrosis in a subject. As described herein, subjects with HPS who have, will develop, Cor are most at risk or developing pulmonary fibrosis have elevated levels of CHI3L1.... Brown University

Neuroprotective composition and use

A therapeutic composition for treating brain injury comprising a polyarginine peptide of from 5 to 9 arginines, and further comprising 1 or more terminal cysteines. The composition is administered in therapeutically effective dosages prophylactically or as soon as possible post-injury in treating neuronal injury.... Brown University

High frequency light emission device

Systems, apparatuses, and methods for modulating light at high frequencies by addressing the issue of direct modulation of long lifetime light emitters. Dynamic control of the local density of optical states (LDOS) to exploit the differences between electric and magnetic dipole transitions allows for higher frequency modulation. The LDOS is... Brown University

Method and system for unsynchronized structured lighting

A system and method to capture the surface geometry a three-dimensional object in a scene using unsynchronized structured lighting is disclosed. The method and system includes a pattern projector configured and arranged to project a sequence of image patterns onto the scene at a pattern frame rate, a camera configured... Brown University

Methods using dna methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies

Methods using DNA Methylation arrays are provided for identifying a cell or mixture of cells and for quantification of alterations in distribution of cells in blood or in tissues, and for diagnosing, prognosing and treating disease conditions, particularly cancer. The methods use fresh and archival samples.... Brown University

Parameterized model of 2d articulated human shape

Disclosed are computer-readable devices, systems and methods for generating a model of a clothed body. The method includes generating a model of an unclothed human body, the model capturing a shape or a pose of the unclothed human body, determining two-dimensional contours associated with the model, and computing deformations by... Brown University

System and methods for mobile medical monitoring

A portable monitoring device for whole-body monitoring can include a receiver configured to receive wireless signals representing real-time neural activity from a neural sensor and to process the wireless signals into digital signals. The portable monitoring device can also include a first processor coupled to the receiver configured to receive... Brown University

System for electronically generating music

A musical instrument for electronically producing music from audio segments. The musical instrument comprises: an apparatus having a first surface; a plurality of selectable elements disposed in a substantially circular geometry on the first surface; and at least one memory storing the plurality of audio segments, each of the plurality... Brown University








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