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Caribou Biosciences Inc patents


Recent patent applications related to Caribou Biosciences Inc. Caribou Biosciences Inc is listed as an Agent/Assignee. Note: Caribou Biosciences Inc may have other listings under different names/spellings. We're not affiliated with Caribou Biosciences Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "C" | Caribou Biosciences Inc-related inventors


Cells comprising engineered nucleic-acid targeting nucleic acids

The present disclosure provides engineered cross-type-nucleic-acid targeting nucleic acids and compositions thereof. Nucleic acid sequences encoding the engineered cross-type-nucleic-acid targeting nucleic acids, as well as expression cassettes, vectors and cells comprising such nucleic acid sequences, are described. Also, methods are disclosed for making and using the engineered cross-type-nucleic-acid targeting nucleic... Caribou Biosciences Inc

Modified cascade ribonucleoproteins and uses thereof

A clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for adaptive antiviral defence (Cascade); the Cascade protein complex comprising at least CRISPR-associated protein subunits Cas7, Cas5 and Cas6 which includes at least one subunit with an additional amino acid sequence possessing nucleic acid or chromatin modifying, visualising, transcription activating or... Caribou Biosciences Inc

Engineered nucleic acids-targeting nucleic acids

The present disclosure provides engineered polynucleotide sequences that form scaffolds and nucleoprotein complexes comprising such engineered polynucleotide sequences that form scaffolds and nucleic acid binding proteins. Nucleic acid sequences encoding the engineered polynucleotide sequences that form scaffolds, as well as expression cassettes, vectors and cells comprising such polynucleotide sequences, are... Caribou Biosciences Inc

Compositions and methods of engineered crispr-cas9 systems using split-nexus cas9-associated polynucleotides

The present specification discloses engineered Type II CRISPR-Cas9 systems comprising split-nexus Cas9-associated polynucleotides (sn-casPNs), including systems comprising three split-nexus Cas9-associated polynucleotides (sn1-casPN/sn2-casPN/sn3-casPN) and systems comprising two split-nexus Cas9-associated polynucleotides (sn1-casPN/sn2-casPN). Together with a Cas9 protein, the sn-casPNs facilitate site-specific modifications, including cleavage and mutagenesis, of a target polynucleotide in vitro... Caribou Biosciences Inc

Compositions and methods of engineered crispr-cas9 systems using split-nexus cas9-associated polynucleotides

The present specification discloses engineered Type II CRISPR-Cas9 systems comprising split-nexus Cas9-associated polynucleotides (sn-casPNs), including systems comprising three split-nexus Cas9-associated polynucleotides (sn1-casPN/sn2-casPN/sn3-casPN) and systems comprising two split-nexus Cas9-associated polynucleotides (sn1-casPN/sn2-casPN). Together with a Cas9 protein, the sn-casPNs facilitate site-specific modifications, including cleavage and mutagenesis, of a target polynucleotide in vitro... Caribou Biosciences Inc

Compositions and methods of nucleic acid-targeting nucleic acids

This disclosure provides for compositions and methods for the use of nucleic acid-targeting nucleic acids and complexes thereof.... Caribou Biosciences Inc

Engineered nucleic-acid targeting nucleic acids

The present disclosure provides engineered cross-type-nucleic-acid targeting nucleic acids and compositions thereof. Nucleic acid sequences encoding the engineered cross-type-nucleic-acid targeting nucleic acids, as well as expression cassettes, vectors and cells comprising such nucleic acid sequences, are described. Also, methods are disclosed for making and using the engineered cross-type-nucleic-acid targeting nucleic... Caribou Biosciences Inc

Engineered nucleic acid-targeting nucleic acids

The present disclosure provides engineered polynucleotide sequences that form scaffolds and nucleoprotein complexes comprising such engineered polynucleotide sequences that form scaffolds and nucleic acid binding proteins. Nucleic acid sequences encoding the engineered polynucleotide sequences that form scaffolds, as well as expression cassettes, vectors and cells comprising such polynucleotide sequences, are... Caribou Biosciences Inc

Rna modification to engineer cas9 activity

The disclosure provides for compositions, methods and kits, for reducing off-target effects of genome engineering.... Caribou Biosciences Inc

Engineered nucleic-acid targeting nucleic acids

The present disclosure provides engineered cross-type-nucleic-acid targeting nucleic acids and compositions thereof. Nucleic acid sequences encoding the engineered cross-type-nucleic-acid targeting nucleic acids, as well as expression cassettes, vectors and cells comprising such nucleic acid sequences, are described. Also, methods are disclosed for making and using the engineered cross-type-nucleic-acid targeting nucleic... Caribou Biosciences Inc

Directed nucleic acid repair

The present disclosure provides compositions and methods for enhancing directed nucleic acid repair, which are useful in the area of genome engineering.... Caribou Biosciences Inc

Compositions and methods of nucleic acid-targeting nucleic acids

This disclosure provides for compositions and methods for the use of nucleic acid-targeting nucleic acids and complexes thereof.... Caribou Biosciences Inc

Compositions and methods of engineered crispr-cas9 systems using split-nexus cas9-associated polynucleotides

The present specification discloses engineered Type II CRISPR-Cas9 systems comprising split-nexus Cas9-associated polynucleotides (sn-casPNs), including systems comprising three split-nexus Cas9-associated polynucleotides (sn1-casPN/sn2-casPN/sn3-casPN) and systems comprising two split-nexus Cas9-associated polynucleotides (sn1-casPN/5n2-casPN). Together with a Cas9 protein, the sn-casPNs facilitate site-specific modifications, including cleavage and mutagenesis, of a target polynucleotide in vitro... Caribou Biosciences Inc

Compositions and methods of engineered crispr-cas9 systems using split-nexus cas9-associated polynucleotides

The present specification discloses engineered Type II CRISPR-Cas9 systems comprising split-nexus Cas9-associated polynucleotides (sn-casPNs), including systems comprising three split-nexus Cas9-associated polynucleotides (sn1-casPN/sn2-casPN/sn3-casPN) and systems comprising two split-nexus Cas9-associated polynucleotides (sn1-casPN/sn2-casPN). Together with a Cas9 protein, the sn-casPNs facilitate site-specific modifications, including cleavage and mutagenesis, of a target polynucleotide in vitro... Caribou Biosciences Inc








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



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