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Cellcentric Ltd patents


Recent patent applications related to Cellcentric Ltd. Cellcentric Ltd is listed as an Agent/Assignee. Note: Cellcentric Ltd may have other listings under different names/spellings. We're not affiliated with Cellcentric Ltd, we're just tracking patents.

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Isoxazolyl substituted benzimidazoles

A compound which is a benzimidazolyl isoxazole of formula (i): wherein: r0 and r, which are the same or different, are each h or c1-6 alkyl; r9, r9 and r9, which are the same or different, are each h or f; x is -(alkn-, -alk-c(═o)—nr—, -alk-nr—c(═o)— or -alk-c(═o)—; r1 is selected from —s(═o)2r′; a 4- to 6-membered, c-linked heterocyclic group which is unsubstituted or substituted; and an n-linked spiro group of the following formula: r2 and r2′, which are the same or different, are each h or c1-6 alkyl, or r2 and r2′ form, together with the c atom to which they are attached, a c3-6 cycloalkyl group; r3 and r3, which are the same or different, are each h, c1-6 alkyl, oh or f; r4 is phenyl or a 5- to 12-membered, n-containing heteroaryl group and is unsubstituted or substituted; alk is c1-6 alkylene; r′ is c1-6 alkyl; and n is 0 or 1; or a pharmaceutically acceptable salt thereof. The compound has activity in modulating the activity of p300 and/or cbp and is used to treat cancer, particularly prostate cancer.. ... Cellcentric Ltd

Isoxazolyl substituted imidazopyridines

A compound which is an isoxazolyl imidazopyridine of formula (i): wherein: r0 and r, which are the same or different, are each h or c alkyl; r9′ and r9″, which are the same or different, are each h or f; x is -(alk)n-, -alk-c(═o)—nr—, -alk-nr—c(═o)— or -alk-c(═o)—; r1 is selected from —s(═o)2r′ and a 4- to 7-membered heterocyclic group which is unsubstituted or substituted; r2 and r2′, which are the same or different, are each h or c1-6 alkyl; or r2 and r2′ form, together with the c atom to which they are attached, a c3-6 cycloalkyl group; r3 and r3′, which are the same or different, are each h, c1-6 alkyl, oh or f; r4 is phenyl or a 5- to 12-membered n-containing heteroaryl group and is unsubstituted or substituted; alk is c1-6 alkylene; r′ is c1-6 alkyl; and n is 0 or 1; or a pharmaceutically acceptable salt thereof. The compound has activity in modulating the activity of p300 and/or cbp and is used to treat cancer.. ... Cellcentric Ltd








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