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Cellular Dynamics International Inc patents


Recent patent applications related to Cellular Dynamics International Inc. Cellular Dynamics International Inc is listed as an Agent/Assignee. Note: Cellular Dynamics International Inc may have other listings under different names/spellings. We're not affiliated with Cellular Dynamics International Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "C" | Cellular Dynamics International Inc-related inventors


Methods for differentiating pluripotent cells

Methods are provided, in some aspects, for differentiating pluripotent cells into midbrain dopaminergic (DA) neurons using a mono-SMAD inhibition or inhibition of SMAD signaling with only one SMAD inhibitor. In some embodiments, mono-SMAD inhibition utilizes a single inhibitor of bone morphogenic protein (BMP) for differentiating pluripotent cells into midbrain DA... Cellular Dynamics International Inc

Production of midbrain dopaminergic neurons and methods for the use thereof

Methods are provided for efficient production of midbrain dopaminergic (DA) neurons. In some aspects, methods involve differentiation and selection of DA neurons for a transgenic pluripotent cell population (e.g., cells comprising a selectable marker gene). Cell populations produced by the instant methods and methods of their use are likewise provided.... Cellular Dynamics International Inc

Cardiomyocyte production

Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem... Cellular Dynamics International Inc

Reprogramming t cells and hematopoietic cells

Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from CD34+ hematopoietic cells, such as human CD34+ blood progenitor cells, or T cells. Various iPS cell lines are also provided. In certain embodiments, the... Cellular Dynamics International Inc

Production of virus-receptive pluripotent stem cell (psc)-derived hepatocytes

The present disclosure provides methods for maturing hepatocytes comprising culturing with cyclic adenosine monophosphate and a Janus kinase inhibitor. There is also provided a method for screening inhibitors of hepatitis B virus infection and/or replication.... Cellular Dynamics International Inc

Hepatocyte production via forward programming by combined genetic and chemical engineering

The present invention provides methods comprising both genetic and chemical means for the production of hepatocytes from a variety of cell sources, particularly pluripotent stem cells.... Cellular Dynamics International Inc

Multi-lineage hematopoietic precursor cell production by genetic programming

The present disclosure generally regards methods and compositions for providing multi-lineage hematopoietic precursor cells from pluripotent stem cells (PSCs). The PSCs comprise an expression construct encoding an ETS/ERG gene, GATA2 and HOXA9. Also provided are methods for providing hematopoietic stem cells capable of long-term engraftment in mammals, such as humans.... Cellular Dynamics International Inc

Generation of induced pluripotent stem cells from small volumes of peripheral blood

Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from peripheral blood cells, such as human blood progenitor cells, using episomal reprogramming and feeder-free or xeno-free conditions. In certain embodiments, the invention provides novel... Cellular Dynamics International Inc

Macs-based purification of stem cell-derived retinal pigment epithelium

Provided herein are methods of enriching a retinal pigment epithelium (RPE) cell population derived from stem cells. Such a method may comprise removing contaminating cells through the depletion of CD24 positive cells, CD56 positive cells, and/or CD90 positive cells from a starting population of RPE cells.... Cellular Dynamics International Inc








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