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Centre National De La Recherche Scientifique
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Centre National De La Recherche Scientifique patents


Recent patent applications related to Centre National De La Recherche Scientifique. Centre National De La Recherche Scientifique is listed as an Agent/Assignee. Note: Centre National De La Recherche Scientifique may have other listings under different names/spellings. We're not affiliated with Centre National De La Recherche Scientifique, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "C" | Centre National De La Recherche Scientifique-related inventors


 new patent  Method for characterising ions

A method for characterising ions includes trapping a first-generation ions in an ion trap; cooling the plurality of first-generation ions; photo-fragmenting the plurality of cooled first generation ions to obtain a plurality of second-generation ions, the second-generation ions being different to the first-generation ions, the plurality of second-generation ions being at least of one first type; selecting the first type of second-generation ions in the ion trap by ejecting, out of the trap, any residual first-generation ion and any second-generation ion of a type different from the first type; cooling the second-generation ions of the first type selected and trapped in the trap; photo-fragmenting the cooled second-generation ions of the first type to obtain a plurality of third-generation ions, the plurality of third-generation ions being different from the plurality of second-generation ions, the plurality of third-generation ions being at least of one first type; detecting the plurality of last-generation ions.. . ... Centre National De La Recherche Scientifique

 new patent  Cxcl10 as predictive biomarker of renal transplant acute rejection and diagnostic biomarker of antibody-mediated rejection (abmr)

The invention relates to a method for determining whether a renal transplanted patient is at risk of acute rejection, comprising a step of determining the expression level of the cxcl10 polypeptide in a urine sample obtained from said patient until 3-months post-transplantation. The invention also relates to a method for diagnosing antibody-mediated rejection (abmr) in a renal transplanted patient, comprising a step of determining the expression level of the cxcl10 polypeptide in a urine sample obtained from said patient.. ... Centre National De La Recherche Scientifique

 new patent  Methods and pharmaceutical compositions for the treatment of bacterial infections in patients suffering from cirrhosis

The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial infections in patients suffering from cirrhosis. In particular, the present invention relates to a method of treating bacterial infection in a patient suffering from cirrhosis comprising administering to the patient a therapeutically effective amount of a tlr7 and/or tlr8 agonist.. ... Centre National De La Recherche Scientifique

Method and device for imaging by magnetic resonance

A mri device includes: structure applying a main magnetic field on an axis z over a sample zone; structure emitting a magnetic field gradient and structure emitting a radiofrequency pulse, and a controller. The controller performs on the sample zone, a sequence including: a radiofrequency pulse and/or phase at each repetition; and a spatial gradient of the component along the z axis. ... Centre National De La Recherche Scientifique

System for generating waves in a pool

Some embodiments are directed to a system for generating waves in a pool, including, in the region of at least one wall of the pool, at least one water intake mouth connected to a supply source by means of a network of pipes, the network of pipes including at least one pump capable of alternately transferring water from the supply source to the pool and vice versa, the pump being controlled so as to generate, in the region of the water intake mouth, an oscillating flow alternately oriented towards the pool and then towards the supply source.. . ... Centre National De La Recherche Scientifique

Method for the inscription of second-order nonlinear optical properties into an amorphous or vitreous material

A method for the inscription of second-order nonlinear optical properties on a support including an amorphous material, the method including: heating the support within a temperature range allowing the movement of charges inside the support; applying a structured electrode to the support, generating an electrical field designed to induce the formation of non-linear optical properties on the surface of the support; and cooling the support.. . ... Centre National De La Recherche Scientifique

Ln(iii) and ga(iii) metallacrown complexes

The present invention concerns heterometallic metallacrown compounds incorporating ga(iii) and ln(iii) cations, with a templating ligand such as salicylhydroxamic acid or derivatives thereof, wherein said metallacrown contains at least one repeating [—ga—n—o—] sub-unit where the n—o derives from the templating ligand.. . ... Centre National De La Recherche Scientifique

Process for oxidation of alcohols using oxygen-containing gases

A process of oxidizing an alcohol for the production of its corresponding carbonyl compounds is disclosed, wherein the oxidation is performed with oxygen or gases containing oxygen in the presence of a catalyst comprising at least a gold compound and a copper compound. Said alcohol oxidation by gaseous oxidant can achieve a high yield and selectivity with minimized degradation products or waste organic solvents.. ... Centre National De La Recherche Scientifique

Dendri-tac and their use as theranostics

The present invention relates to novel amphiphilic dendrimers, hereafter denoted dendri-tac. The present invention also relates to perfluorocarbon nanoemulsions stabilized by these amphiphilic dendrimers and their uses for in vivo diagnostic and/or for therapy, notably as theranostic tools, for detection and/or treatment of cancer.. ... Centre National De La Recherche Scientifique

Method for preserving cells, tissues or organs in hypothermia

The present invention relates to a method for preserving, preferably human, cells, tissues or organs in severe hypothermia, comprising a step during which the cells, tissues or organs are kept in moderate hypothermia and preferably in a hypoxic and/or hypercapnic atmosphere, before placing them in severe hypothermia.. . ... Centre National De La Recherche Scientifique

Polynucleotide responsible of haploid induction in maize plants and related processes

The present invention concerns an isolated polynucleotide responsible of haploid induction in maize plants and related processes. Additionally, the invention relates to plants that have been genetically transformed with the polynucleotide of the invention. ... Centre National De La Recherche Scientifique

Heat exchanger comprising microstructure elements and separation unit comprising such a heat exchanger

The invention relates to a heat exchanger comprising parallel plates and spacers arranged in parallel and defining i) rough primary channels and ii) secondary channels arranged so as to exchange heat. Said heat exchanger comprises a primary liquid inlet to be fluidically connected to a primary liquid dispenser. ... Centre National De La Recherche Scientifique

Polypeptide having the capacity to form alpha-1,3 glucosyl unit branchings on an acceptor

Polypeptides having the ability to specifically form connections of glucosyl units in alpha 1,3 on an acceptor having at least one hydroxyl moiety are presented. The polypeptides include i) the pattern i of sequence seq id no: 1, ii) the pattern ii of sequence seq id no: 2, iii) the pattern iii of sequence seq id no: 3, and iv) the pattern iv of sequence seq id no: 4, or derivates from one or several of said patterns, wherein the polypeptide furthermore has an aspartic residue (d) at position 5 of the pattern ii (seq id no: 2), a glutamic acid residue (e) at position 6 of the pattern iii (seq id no: 3) and an aspartic acid residue (d) at position 6 of the pattern iv (seq id no: 4). ... Centre National De La Recherche Scientifique

Solar device for autonomous refrigeration by solid-gas sorption

A device is provided for the autonomous production of refrigeration approximately 40° c. Lower than ambient temperature from a low-temperature solar thermal source, the device including: (i) a reactor arranged to cool and/or heat the solid reagent; (ii) a condenser; (iii) a first tank for storing the liquid refrigerant at ambient temperature; (iv) an enclosure arranged to store a phase-change material and also including an evaporator; (v) a second tank for storing the liquid refrigerant at a low temperature; (vi) apparatus for conveying the refrigerant and (vii) apparatus for controlling the flow of the refrigerant.. ... Centre National De La Recherche Scientifique

04/05/18 / #20180097563

Free space optical communications device

The invention relates to a free space optical communications device (10) multiplexed in wavelengths of between 400 nm and 1600 nm, said device including demultiplexing means (11) that are designed so as to separately dissociate a number n1 of wavelengths from one another, the demultiplexing means (11) including one or more detectors (110) having a number n2 of optical filters (111) and active elements (112) which correspond to the number n1 of wavelengths, each active element (112) being arranged to selectively detect one wavelength from among said wavelengths (id. . ... Centre National De La Recherche Scientifique

04/05/18 / #20180094105

Aqueous dispersion of particles of at least one thermoplastic polymer, method for preparing and applications thereof, especially for sizing reinforcing fibres

The invention relates to the use of giant micelles as shear-thinning agent in an aqueous dispersion of particles of at least one thermoplastic polymer. It also relates to an aqueous dispersion of particles of at least one thermoplastic polymer, comprising giant micelles located around the particles of the thermoplastic polymer(s), and also to a method that makes it possible to prepare this aqueous dispersion. ... Centre National De La Recherche Scientifique

03/29/18 / #20180090906

Method and device for triggering pulsed light sources

The invention relates to a method for triggering a pulsed light source, wherein it comprises at least one iteration of the following steps: receiving a control signal; determining what is called a separation time between the reception of said control signal and at least one preceding control signal; adjusting at least one control parameter of said pulsed light source depending at least on said separation; generating at least one electrical signal for triggering the pulsed light source depending on said at least one control parameter adjusted during the preceding step; and triggering the pulsed light source depending on said at least one triggering electrical signal.. . ... Centre National De La Recherche Scientifique

03/29/18 / #20180088232

Method and device for probing by wave propagation

A method for probing by wave propagation, in which an incident wave is emitted into a medium comprising diffusers that can reflect the wave. Signals representing a reflected wave reverberated by the medium from the incident wave are captured, said captured signals being the sum of a simple diffusion component and a multiple diffusion component. ... Centre National De La Recherche Scientifique

03/22/18 / #20180084625

Control of pixel addressable led strips

A system of control of interconnected signal emitters comprises controller modules, microcontrollers, electronic drivers and signal emitters. The connection input of each electronic driver is connected to the output of another electronic driver or to the output of a microcontroller, and the single output of each electronic driver is connected to the single connection input of another electronic driver or to the output of a microcontroller; each electronic driver being part of a driver chain between controller modules. ... Centre National De La Recherche Scientifique

03/15/18 / #20180074304

Optical system for shaping the wavefront of the electric field of an input light beam

The present invention concerns an optical system for shaping the wavefront of the electric field of an input light beam (1) to be projected into a target volume (5), including: —a first optical element (2), which is a spatial light modulator used to control light distribution in at least one transverse plane (51, 52, 53) in the target volume (5), —at least one intermediate optical element (4) being located, on an optical axis (z), after the first optical element (2) on a trajectory of the light beam (1) for modulating the phase and/or the amplitude of the electric field of the input light beam, and —a second optical element (3) for modulating the phase and/or the amplitude of the electric field of the input light beam, and used to control the axial position of the at least one transverse plane (51, 52, 53) in the target volume (5), the second optical element (3) being situated on the optical axis (z) after the at least one intermediate optical element (4) on the trajectory of the light beam (1).. . ... Centre National De La Recherche Scientifique

03/15/18 / #20180071430

Injectable collagen suspensions, the preparation method thereof, and the uses thereof, particularly for forming dense collagen matrices

Disclosed is the preparation of injectable collagen suspensions, to the method for preparing the suspensions, and to the uses thereof, particularly for forming dense collagen matrices.. . ... Centre National De La Recherche Scientifique

03/15/18 / #20180071413

Non-invasive imaging of tumor pd-l1 expression

The present invention relates to a method for detecting a pd-l1-positive tumor in a patient by imaging using a radiolabelled anti-pd-l1 antibody.. . ... Centre National De La Recherche Scientifique

03/08/18 / #20180066338

Single-phase alloy of gold and tungsten

A single-phase alloy is formed, as weight percentages, of n % of gold, m % of tungsten, with n+m=100, m≧8 and n≧60. Also disclosed is a process for preparing such an alloy use of such an alloy and decorative sheets made from such an alloy.. ... Centre National De La Recherche Scientifique

03/08/18 / #20180066283

Widespread gene delivery to motor neurons using peripheral injection of aav vectors

The present invention relates to compositions and methods, in particular to methods based on systemic injection of raav, for delivering genes to cells of the central nervous system in mammals, such as brain neurons or glial cells, and in particular to motor neurons or glial cells of the spinal cord the invention also relates to methods of treating motor neuron disorders in mammals by expression of therapeutic genes. The invention stems from the unexpected discovery that peripheral injection of aav vectors leads to a bypass of the blood brain barrier and a massive infection of motor neurons. ... Centre National De La Recherche Scientifique

03/08/18 / #20180064825

Anti-pd-l1 immunotoxin for use in therapy

The present disclosure relates to a combination of an anti-pd-l1 (programmed cell death 1 ligand 1) with an ‘immunotoxin’ for use in a method for treating a tumor in a patient. Experimental results are provided for a combination of an anti pol 1 antibody with the radioisotope indium 111.. ... Centre National De La Recherche Scientifique

03/01/18 / #20180059412

Method for tuning one or more resonator(s)

The invention concerns a method for tuning at a targeted resonance wavelength at least one micro and/or nanophotonic resonator, the resonator having dimensions defining resonance wavelength of said resonator, the resonator being immersed in a fluid containing ions so that the resonator is surrounded by said fluid, wherein the method comprises a step of injecting light, having a light wavelength equal to the resonance wavelength, into the resonator, so that the injected light resonates within the resonator and triggers a photo-electrochemical etching process enabled by the surrounding fluid containing ions, said etching process being enhanced by the optical resonance which amplifies light intensity in the photonic resonator, the etching decreasing dimensions of the photonic resonator, hereby lowering and tuning the resonance wavelength of the photonic resonator.. . ... Centre National De La Recherche Scientifique

03/01/18 / #20180057383

Novel radioresistant alga of the genus coccomyxa

The invention relates to novel algae of the genus coccomyxa, in particular the algae of a new species called c-ir3-4c, and their use for capturing metals from aqueous media, and in particular from radioactive media.. . ... Centre National De La Recherche Scientifique

02/22/18 / #20180049387

Novel method for promoting nodulation in plants

Micropeptides (mipeps), or peptides coded by micrornas, for promoting nodulation between a plant and a bacterium, as well as their use in this manner.. . ... Centre National De La Recherche Scientifique

02/22/18 / #1) hydrocarbon-based polymer of formula (i):

Centre National De La Recherche Scientifique

. . ... Centre National De La Recherche Scientifique

02/15/18 / #the invention concerns a numerical calculation procedure of the diffraction of a structure (1) whose numerical model defines the dielectric permittivity at each point comprizing the steps of:

Centre National De La Recherche Scientifique

. . ... Centre National De La Recherche Scientifique

02/15/18 / #20180045711

Method and device for detecting in real time a secreted compound and the secretion target, and uses thereof

A method for measuring in real time a secretion of a compound by a target, and a device implementing the method, the method including: culturing, in a liquid medium, in a culture chamber, a plurality of targets including at least one target, the culture chamber including: (i) at least one 1st surface on which the target is present, presence of the target generating a 1st signal; and (ii) at least one 2nd surface that is different from the 1st surface and not coplanar with the 1st surface, which surface is functionalized by at least one ligand specifically binding to the compound secreted by the target, the specific bond between the ligand and the compound generating a 2nd signal that is distinct from the 1st signal; and detecting in real time the 2nd signal and optionally the 1st signal.. . ... Centre National De La Recherche Scientifique

02/15/18 / #20180044653

Mutant yeast strain capable of degrading cellobiose

The invention relates to a method for obtaining a mutant oleaginous yeast strain capable of growing on cellobiose as carbon source, comprising overexpressing in said strain two β-glucosidase enzymes further comprising a n-terminal signal peptide. The invention also relates to a mutant yeast strain obtained by said method.. ... Centre National De La Recherche Scientifique

02/15/18 / #20180044249

A method of fabricating a composite material part by self-propagating high temperature synthesis

A method of fabricating a part made of ceramic matrix composite material, the method includes fabricating the part by forming a ceramic matrix in the pores of a fiber structure, the ceramic matrix being formed by self propagating high temperature synthesis from a powder composition present in the pores of the fiber structure,. . ... Centre National De La Recherche Scientifique

02/15/18 / #20180044241

Refractory block and glass-melting furnace

A molten refractory product having the following average chemical composition, in wt % on the basis of oxides and for a total of 100%: al2o3: balance to 100%; fe2o3: 0.6%-5.0% and/or tio2: 1.5%-10.0%; fe2o3+tio2≦10.0%; na2o+k2o: 1.0%-8.0%; sio2: 0.2%-2.0%; cao+bao+sro: ≦0.5%; other oxide species: ≦1.5%. Also, a glass-melting furnace and the use of the refractory product in the glass-melting furnace.. ... Centre National De La Recherche Scientifique

02/15/18 / #20180042979

Use of a withania extract for the treatment of amyloid-related diseases

The invention relates to the use of a composition from a plant extract of withania somnifera, to treat or prevent amyloid-related diseases, including alzheimer disease.. . ... Centre National De La Recherche Scientifique

02/08/18 / #20180038842

Microfluidic device and apparatus comprising such a device

The microfluidic device comprises a body and a covering sheet. The body comprises a base section that includes an exterior surface and a channel bottom which extends in a main longitudinal direction and which is formed in the base section in the exterior surface. ... Centre National De La Recherche Scientifique

02/08/18 / #20180038748

Method and device for measuring the following of a path under load

A device for measuring a path under load of a first part that is in motion relative to a second part. The device includes an active telescopic bar and a connector. ... Centre National De La Recherche Scientifique

02/08/18 / #20180037934

Microfluidic process for treating and analysing a solution containing a biological material and corresponding microfluidic circuit

The subject matter of the present invention is a microfluidic process for treating and analysing a solution containing a biological material, comprising a step of introducing the solution into microchannels of a microfluidic circuit (1), a step of forming drops of this solution, under the effect of modifications of the surface tension of the solution, a step of moving the drops to one or more drop storage zones(s) (130), under the effect of modifications of the surface tension of the drops, a step of treating the drops and a step of analysing the drops.. . ... Centre National De La Recherche Scientifique

02/08/18 / #20180036220

Hyaluronic acid particles for cosmetic or dermatological uses

In the field of cosmetics or pharmaceuticals, and particularly to the dermatological field, disclosed are particles containing hyaluronic acid modified by hydrophobic groups and the use thereof as an agent for stimulating the epidermis and/or dermis. In particular, the assemblies are useful on the one hand, as a moisturising and/or plumping and/or volumising agent. ... Centre National De La Recherche Scientifique

02/01/18 / #20180030860

Device for the transmission of kinetic energy from a working fluid to a receiving fluid

A system for exchanging heat from a working fluid to a receiving fluid, which includes: a device for transmitting kinetic energy from a working fluid to a receiving fluid, the device including: a circulator suitable for circulating the receiving fluid; a turbine suitable for being driven by the circulation of the working fluid; and a shaft coupling the turbine to the circulator; a heat transfer system for transferring heat from the working fluid by heat transfer from the receiving fluid; and a mixing system for mixing the receiving fluid and the heated working fluid.. . ... Centre National De La Recherche Scientifique

02/01/18 / #20180030196

Method for manufacturing a polyurethane-modified foam, foam obtained, and uses

Disclosed is a method for manufacturing an isocyanurate polyurethane-modified foam, called “puir,” including: a) providing an oil or oil mixture at least 50% by weight of the fatty acids having a carbon chain of c18 or more, the fatty acids having an overall iodine number iiodine of at least 100 g of i2/100 g; b) epoxidating at least 50% of the double bonds in the oil to form the corresponding epoxides; and c) directly reacting, in situ, the epoxides that are obtained above with isocyanate or diisocyanate groups for obtaining corresponding oxazolidone derivatives, without passing through the intermediate formation of polyols obtained from epoxides, in the presence of at least one suitable catalyst and at least one expanding agent, so as to obtain the isocyanurate polyurethane-modified foam “puir.” also disclosed are products, such as rigid insulation material, in particular as a material or panels of rigid insulation for roofing.. . ... Centre National De La Recherche Scientifique

02/01/18 / #20180030136

Icos binding proteins

The present invention relates to an icos binding protein or antigen binding portion thereof that is an agonist to human icos and does not induce complement, adcc, or cdc when placed in contact with a t cell in vivo and methods of treating cancer, infectious disease and/or sepsis with said icos binding protein or antigen binding portion thereof. Further the icos binding proteins or antigen binding portions thereof of the present invention are capable of activating a t cell when placed in contact with said t cell; stimulating t cell proliferation when placed in contact with said t cell and/or inducing cytokine production when placed in contact with said t cell. ... Centre National De La Recherche Scientifique

02/01/18 / #20180030117

Synthetic single domain antibody

The invention relates to the identification of a highly stable single domain antibody scaffold (hs2d ab) and its use in generating synthetic single domain antibody library (hs2d ab-l1). The invention also relates to antigen-binding proteins comprising said stable single domain antibody scaffold and their uses, in particular as therapeutics.. ... Centre National De La Recherche Scientifique

01/25/18 / #f1 is formula (iia) and f2 is formula (iib):

Centre National De La Recherche Scientifique

. . ... Centre National De La Recherche Scientifique

01/25/18 / #a system controls a cyclic motion of at least one body segment of an individual, including:

Centre National De La Recherche Scientifique (cnrs)

. . ... Centre National De La Recherche Scientifique

01/25/18 / #20180024095

Non-thermosensitive medium for analyzing species in a channel and for minimizing adsorption and/or electroosomosic phenomena

An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. ... Centre National De La Recherche Scientifique

01/25/18 / #20180023056

Reprogramming method for producing induced pluripotent stem cells (ipsc)

The present invention is in the field of stem cells. Particularly, the present invention relates to a reprogramming method for producing induced pluripotent stem cells (ipsc) by transducing somatic differentiated cells with a viral vector expressing Δ133p53β isoform, Δ133p53γ isoform or both Δ133p53β and Δ133p53γ isoforms; to induced pluripotent stem cells as produced by this method; to uses thereof in cell therapy and as an in vitro model for studying various diseases; and to a method for detecting ipsc.. ... Centre National De La Recherche Scientifique

01/25/18 / #20180022853

Method for producing an ablative resin

A method for producing a propulsion nozzle, wherein the nozzle is produced from an ablative resin, the method including a step of pre-polymerization wherein an innovative aldehyde compound is used.. . ... Centre National De La Recherche Scientifique

01/25/18 / #20180022802

Monoclonal antibodies to progastrin and their uses

The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. ... Centre National De La Recherche Scientifique

01/18/18 / #the invention relates to a method for producing a support for the production of a semiconductor structure based on group iii nitrides, characterised in that the method comprises the steps of:

Centre National De La Recherche Scientifique (cnrs)

. . ... Centre National De La Recherche Scientifique

01/18/18 / #20180016577

Treatment of facioscapulohumeral dystrophy

The present invention relates to nucleic acids, compositions and methods for the treatment of facioscapulohumeral dystrophy.. . ... Centre National De La Recherche Scientifique

01/18/18 / #20180016398

Novel silicone composition crosslinking catalysts

The invention relates to a crosslinkable composition x, comprising: at least one organopolysiloxane compound a comprising, per molecule, at least two c2-c6 alkenyl radicals bonded to silicon atoms; at least one organohydrogenopolysiloxane compound b comprising, per molecule, at least two hydrogen atoms bonded to an identical or different silicon atom; at least one catalyst c which is a complex corresponding to the following formula: [co(l1)2] in which: the symbol co represents cobalt at degree of oxidation ii; the symbols l1, which may be identical or different, represent a ligand which is a β-dicarbonylato anion or the enolate anion of a β-dicarbonylated compound; optionally at least one adhesion promoter d; and optionally at least one charge e. The invention also relates to the use of the previously described catalyst c as silicone composition crosslinking catalyst, to a silicone composition crosslinking method, characterized in that it consists in heating the composition x to a temperature of between 70 and 200° c., and to the resulting crosslinked silicone material y.. ... Centre National De La Recherche Scientifique

01/18/18 / #20180016322

Antibodies specific to glycoprotein (gp) of ebolavirus and uses for the treatment and diagnosis of ebola virus infection

The present invention relates to antibodies or fragments thereof that specifically bind to glycoprotein (gp) of ebola virus, and to their use for treating and diagnosing ebola virus disease.. . ... Centre National De La Recherche Scientifique

01/18/18 / #20180014775

Ankle ergometer

Disclosed is an ankle ergometer for measuring a force exerted on a user's ankle joint by muscles involved in ankle mobility, including: a first splint-type portion receiving the lower limb when the user's knee is extended, and including a lower limb immobilizer with the leg in extension, and a second portion including: a) a main body attached to the first portion, b) a counter-supporting unit secured to the main body, c) a rigid plate forming a supporting surface for the lower surface of the foot, the rigid plate being substantially static relative to the counter-supporting unit, d) a force sensor between the plate and the counter-supporting unit, the plate not being secured to the main body so the sensor measures the force exerted on the supporting surface of the plate by the ankle mobility muscles, the force being transmitted from the plate to the counter-supporting unit.. . ... Centre National De La Recherche Scientifique

01/11/18 / #the invention relates to a method for producing a semiconductor structure, characterised in that the method comprises a step (201) of depositing a crystalline passivation layer continuously covering the entire surface of a layer based on group iii nitrides, said crystalline passivation layer, which is deposited from a precursor containing silicon atoms and a flow of nitrogen atoms, consisting of silicon atoms bound to the surface of the layer based on group iii nitrides and arranged in a periodical arrangement such that a diffraction image of said crystalline passivation layer obtained by grazing-incidence diffraction of electrons in the direction [1-100] comprises:

Centre National De La Recherche Scientifique (cnrs)

. . ... Centre National De La Recherche Scientifique

01/11/18 / #20180010109

Polypeptide fragments comprising endonuclease activity and their use

The present invention relates to polypeptide fragments comprising an amino-terminal fragment of the pa subunit of a viral rna-dependent rna polymerase or variants thereof possessing endonuclease activity, wherein said pa subunit is from a virus belonging to the orthomyxoviridae family. This invention also relates to (i) crystals of the polypeptide fragments which are suitable for structure determination of said polypeptide fragments using x-ray crystallography and (ii) computational methods using the structural coordinates of said polypeptide to screen for and design compounds that modulate, preferably inhibit the endonucleolytically active site within the polypeptide fragment. ... Centre National De La Recherche Scientifique

01/11/18 / #20180009928

Method for producing an ablative resin

A method for producing an ablative resin by carrying out a reduction reaction for the reduction of a compound of formula a, followed by a polymerization reaction, formula a being the following:. . ... Centre National De La Recherche Scientifique

01/11/18 / #20180009669

Method for preparing a material made from aluminosilicate and method for preparing a composite material having an aluminosilicate matrix

The invention relates to a method for preparing a material based on an aluminosilicate selected from barium aluminosilicate bas, barium-strontium aluminosilicate bsas, and strontium aluminosilicate sas, said aluminosilicate consisting of aluminosilicate with a hexagonal structure, characterised in that it includes a single sintering step in which a mixture of powders of precursors of said aluminosilicate, including an aluminium hydroxide al(oh)3 powder, are sintered by a hot-sintering technique with a pulsed electric field sps; whereby a material based on an aluminosilicate, said aluminosilicate consisting of an aluminosilicate with a hexagonal structure is obtained. The material based on an aluminosilicate prepared by said method can be used in a method for preparing a composite material consisting of an aluminosilicate matrix reinforced by reinforcements made of metalloid or metal oxide.. ... Centre National De La Recherche Scientifique

01/11/18 / #20180009664

Method for synthesizing carbon materials from carbon agglomerates containing carbine/carbynoid chains

Provided is a method for synthesizing carbon agglomerates containing metastable carbyne/carbynoid chains; a method for synthesizing carbon or carbon compound allotropes from the agglomerates containing metastable carbyne/carbynoid chains; and the uses of the methods. The method for synthesizing carbon agglomerates containing metastable carbyne/carbynoid chains includes the following steps: a) forming carbon vapor precursors, containing carbine/carbynoid chains, by decomposing a carbon gas selected from among ch4, c2h2, c2h4, gaseous toluene, and benzene in the form of vapors at a temperature t such that 1 500° c.<t≦3 000° c.; and b) condensing the carbon vapor precursors, obtained in step a), on the surface of a substrate, the temperature ts of which is less than the temperature t. ... Centre National De La Recherche Scientifique

01/11/18 / #20180009103

Planar motion device

A positioning device includes a planar surface, a mobile platform configured to slide along the planar surface and cables for positioning and moving the mobile platform along the planar surface. The mobile platform includes a planar bearing system located at the side of the mobile platform configured to slide along the planar surface. ... Centre National De La Recherche Scientifique

01/04/18 / #20180006164

Opto-electronic device with textured surface and method of manufacturing thereof

Disclosed is an opto-electronic device including a semiconducting substrate, a layered interface including at least one layer, the layered interface having a first surface in contact with a surface of the semiconducting substrate and the layered interface being adapted for passivating the surface of the semiconducting substrate, the layered interface having a second surface and the layered interface being adapted for electrically insulating the first surface from the second surface, and a textured surface structure including a plurality of nanowires and a transparent dielectric coating, the textured surface structure being in contact with the second surface of the layered interface, the plurality of nanowires protruding from the second surface and the plurality of nanowires being embedded between the second surface and the transparent dielectric coating.. . ... Centre National De La Recherche Scientifique

01/04/18 / #20180003631

Surface plasmon resonance approach to monitor protein-ligand interactions

The present invention provides assays utilizing spr to detect protein-ligand interactions as well as compositions utilized is such assays.. . ... Centre National De La Recherche Scientifique

01/04/18 / #20180000077

Antibacterial composition comprising an acetal or a long-chain alkyl hexitane ether

The present invention relates to a a bactericidal or bacteriostatic composition comprising an acetal or a hexitan ether preferentially of a long-chain alkyl sorbitan, arlitan or mannitan, its use in the treatment or prevention of gram-positive bacterial infections, its use as a hygiene or dermatological product for external use and a method for disinfecting surfaces.. . ... Centre National De La Recherche Scientifique

12/28/17 / #20170370772

Led spectrofluorometer for analysis of an object

An led spectrofluorometer (100) for analysis of an object (101) includes a light excitation element (11, 112, 113) suitable for illuminating a study zone (101b) of the object with an excitation light beam (1), and an optical routing element (121, 122, 123, 124) suitable for collecting a fluorescent light flux (2) emitted by the study zone excited by the excitation light beam and for routing the fluorescent light flux to an optical spectrometer (131) for analysis of the light spectrum thereof. The light excitation element includes a first light-emitting diode (111) and a second-light emitting diode (112), the first light-emitting diode emitting at a first wavelength (λ1) between 250 and 300 nm and the excitation light beam being formed from one or other of the light beams generated by each light-emitting diode.. ... Centre National De La Recherche Scientifique

12/28/17 / #20170369637

Hydrocarbonated polymers with two alcoxysilane end groups

The invention relates to 1) a hydrocarbonated polymer comprising two alcoxysilane end groups of formula (1), and 2) a method for producing said polymer, an adhesive composition comprising said polymer and the use of said adhesive composition.. . ... Centre National De La Recherche Scientifique

12/21/17 / #20170362593

Use of rad18 inhibitors in the treatment of tumors

The present invention relates to the use of an inhibitor of rad18 expression or activity, in treating a tumor or in sensitizing a patient affected with a tumor, to a treatment with an antineoplastic agent that is a dna damaging chemotherapeutic agent so to both reduce the self renewal of cancer stem cells and increase the dna damage response thus boosting apoptotic cell death.. . ... Centre National De La Recherche Scientifique

12/21/17 / #20170360947

Polymer particles and biomaterials comprising the same

The present invention relates to polymer particles comprising antibiotics which are deliverable in situ, as well as a method of preparation thereof. The present invention also relates to bioactive biomaterials for the controlled delivery of antibiotics comprising support materials having such polymer particles on their surface. ... Centre National De La Recherche Scientifique

12/14/17 / #20170355964

Delta133p53beta and delta133p53gamma isoforms are biomarkers of cancer stem cells

The present invention is in the field of oncology, and more particularly of cancer stem cells. It relates to a method for producing cancer stem cells based on overexpression of Δ133ρ536 isoform, Δ133ρ53γ isoform, or both Δ133ρ536 and Δ133ρ53γ isoforms; a method for predicting the risk that treatment with a chemotherapeutic anti-cancer agent induces cancer stem cells in a subject suffering from cancer from a cancer sample of said subject, based on detection of an increase in Δ133ρ536 isoform, Δ133ρ53γ isoform, or both Δ133ρ536 and Δ133ρ53γ isoforms following chemotherapeutic anti-cancer treatment; to therapeutic uses of a combination of chemotherapeutic anti-cancer agent and an agent reducing Δ133p536 isoform, Δ133ρ53γ isoform, or both Δ133ρ536 and Δ133ρ53γ isoforms expression; and also to screening methods for anti-cancer stem cells agents.. ... Centre National De La Recherche Scientifique

12/07/17 / #20170352999

System and method for generating wavelength-tunable, ultra-short light pulses having high power spectral density

Disclosed is a system for generating wavelength-tunable, ultra-short light pulses within the visible or infrared light spectrum. The system includes an injection module including a light source and a wavelength-tunable spectral filter. ... Centre National De La Recherche Scientifique

12/07/17 / #20170351080

Imaging method, and system, for obtaining a super-resolution image of an object

Method for obtaining an super-resolution image (22) of an object (5), based upon an optical microscope (21) including a support plate (6) for bearing the object, an illumination source (1) for focusing an illumination beam (14) onto a target region of the support plate, a digital camera (9) including a matrix of sensors, comprising: capturing, by the digital camera, a first image of the target region; extracting, from the first image, a first block of pixel values provided by a sub-matrix (b0) of the matrix of sensors; displacing, by a sub-diffraction limited distance, the support plate by the displacement block along a displacement axis; capturing, by the digital camera, a second image of the target region; extracting, from the second image, a second block of pixel values provided by the sub-matrix (b0) of the matrix of sensors; storing said first and second blocks of pixel values as a first and second blocks of pixel values to be placed right next each other in the super-resolution image along the image axis (x, y) corresponding to the displacement axis.. . ... Centre National De La Recherche Scientifique

12/07/17 / #20170350889

Cell identification method

The present invention relates to the use of a nucleic acid molecule encoding a first reporter gene, bordered by at least one first pair and one second pair of sequences targeting a site-specific recombinase in order to detect cells of a mammal infected with a virus responsible for an immunodeficiency.. . ... Centre National De La Recherche Scientifique

12/07/17 / #20170349907

Methods to monitor post-translational gene silencing activity in plant tissues/cell types relevant for pathogen entry, propagation or replication

The invention relates to transgenic plants comprising an inverted-repeat construct which triggers post-transcriptional gene silencing of an endogenous visual reporter gene driven by a tissue-specific promoter wherein said tissue is relevant for pathogen entry, propagation or replication and their uses for screening natural or synthetic molecules, microorganisms or extracts from micro- or macro-organisms for their potential ability to inhibit pathogen entry, propagation or replication in plants by enhancing ptgs or for characterizing the mode of action of natural or synthetic molecules that are known to enhance plant disease resistance through an ill-defined mode of action.. . ... Centre National De La Recherche Scientifique

12/07/17 / #20170349810

Nano-inhibitors

Novel hybrid nanoparticles, useful for inhibiting or slowing down the formation of sulfur deposits or minerals in a well during the extraction of gas or oil. Specifically, the nanoparticles each include (i) a polyorganosiloxane (pos) matrix; and, optionally as a coating over a lanthanide oxide core, (iii) at least one polymeric scale inhibitor during the extraction of gas or oil. ... Centre National De La Recherche Scientifique

12/07/17 / #20170349757

Continuous flow process for manufacturing surface modified metal oxide nanoparticles by supercritical solvothermal synthesis

The invention concerns a continuous flow process for manufacturing surface modified metal oxide nanoparticles by supercritical solvothermal synthesis in an reaction medium flowing within a continuous flow chamber, said continuous flow chamber containing a hydrolysis area and a supercritical area, said process comprising the introduction of a flow of metal oxide precursor into the continuous flow chamber at a point p located in the hydrolysis area or in the supercritical area, and the introduction of a flow of is located downstream of p1 with respect to the flow direction, as well as the device for carrying out this process.. . ... Centre National De La Recherche Scientifique

12/07/17 / #20170348462

Hybrid material implant having variable porosity

The invention relates to an implant material for filling bone defects, for bone regeneration, and for bone tissue engineering, to an implant comprising said material, and to methods for manufacturing such an implant. The hybrid implant material according to the invention comprises: a biodegradable polymer p soluble in at least one solvent s1 and insoluble in at least one solvent s, different from the solvent s1; and a bioactive glass made of sio2 and cao and optionally containing p2o5 and/or optionally doped with strontium, characterized in that said implant includes a layering of a porous part having more than 90% by number of pores whose largest dimension is greater than or equal to 100 μm, and a dense part (2, 20, 200, 2000, 20000) having more than 80% by number of pores whose largest dimension is less than 50 μm. ... Centre National De La Recherche Scientifique

12/07/17 / #20170347653

Antibacterial composition containing an isomer mixture of monosaccharide alkyl monoacetals or monoethers

A bactericidal or bacteriostatic composition comprising an isomer mixture of monosaccharide alkyl monoethers or monoacetals, its use in the treatment or prevention of gram-positive bacterial infections, its use as a hygiene or dermatological product for external use and a method for disinfecting surfaces.. . ... Centre National De La Recherche Scientifique

11/30/17 / #this invention relates to a micro-device for detecting volatile compounds comprising:

Centre National De La Recherche Scientifique - Cnrs

. . ... Centre National De La Recherche Scientifique

11/30/17 / #20170346257

Laser device with a beam carrying controlled orbital angular momentum

A laser device is provided for generating a helical-shaped optical wave and includes: (i) a gain region located between one first end defined by a first mirror and a second end defined by an exit region, (ii) a second mirror arranged so as to form with the first mirror an optical cavity including the gain region and a gap between the exit region and the second mirror, (iii) apparatus for pumping the gain region so as to generate the optical wave, wherein the laser device further includes at least one apparatus for shaping the light intensity and/or phase profiles of the optical wave and arranged for selecting at least one rotary-symmetrical transverse mode of the optical wave, the rotary-symmetrical transverse mode being chosen between those with a radial index equal to zero and with an azimuthal index being an integer with a module higher or equal to 1.. . ... Centre National De La Recherche Scientifique

11/30/17 / #20170342274

Aerosol-obtained mesostructured particles loaded with anticorrosion agents

The present invention relates to mesostructured particles that have the particular property of being spontaneously individualized, and that include anticorrosion agents. The invention also relates to a process for preparing these particles, and also to materials obtained by inclusion of these particles in matrices.. ... Centre National De La Recherche Scientifique

11/30/17 / #20170341061

Production of unsaturated carboxylic acids or acid esters with a haloapatite-based catalyst

The present invention relates to the use of haloapatites as catalysts of the dehydration reaction of α-hydroxylated carboxylic acids or acid esters, in particular of lactic acid or of methyl lactate, and also to a process for producing unsaturated carboxylic acids or acid esters, in particular acrylic acid or methyl acrylate, in the gas phase in a stainless steel reactor, in the presence of such a catalyst.. . ... Centre National De La Recherche Scientifique

11/30/17 / #20170340247

Method of testing an infant and suitable device for implementing the test method

The invention relates to a method of testing an infant, comprising the following steps: displaying a target on a screen; detecting contact made by the infant with the screen inside and/or outside the target; calculating a success parameter on the basis of the contact detected; and recording the calculated success parameter in a memory.. . ... Centre National De La Recherche Scientifique

11/23/17 / #20170338208

Electronic power device with vertical 3d switching cell

An electronic power device including: a first electronic power component in which all the electrodes are arranged at a first main face of the first electronic power component; and an electric contact element in which a first main face is arranged against the first main face of the first electronic power component and which includes plural separate electrically conductive portions to which the electrodes of the first electronic power component are electrically connected. The first electronic power component and the electric contact element together form a stack such that a first lateral face of each of the portions of the electric contact element, substantially perpendicular to the first main face of the electric contact element, is arranged against at least one metallization of a support forming an electric contact of the first electronic power component.. ... Centre National De La Recherche Scientifique

11/23/17 / #20170335071

Composition containing bis-ureas for forming stable gels

The invention relates to a composition comprising classic bis-ureas and bis-ureas functionalised by macromolecular chains, said bis-ureas including complementary spacers of the aryl type, the mixture of said bis-ureas in a solvent leading to a stable physical gel. The invention also relates to a method for producing said composition and to the use of said composition as an organogelator, alone or in a cosmetic preparation, an ink, a fuel or a lubricant, especially of a motor vehicle.. ... Centre National De La Recherche Scientifique

11/23/17 / #20170334142

Method for three-dimensional printing

A method for 3d printing, wherein elementary volumes, or voxels, of a material are sequentially transformed by irradiation, including the following steps: breaking down, into identical blocks, the volume of part of an object to be printed that does not require a maximum resolution; for printing, associating with each block a brick having the same contour and comprising hollow portions; and irradiating in order to print the voxels of the bricks.. . ... Centre National De La Recherche Scientifique

11/16/17 / #20170329083

Method for manufacturing a photonic waveguide and photonic waveguide manufactured by said method

Some embodiments are directed to a method for manufacturing photonic waveguides and to photonic waveguides manufactured by this method.. . ... Centre National De La Recherche Scientifique

11/16/17 / #20170327695

Anti-corrosion coatings loaded with mesostructured particles

Coatings, for example polymer coatings or sol-gel coatings, including at least one layer of micrometric, individualised and mesostructured spherical particles. The particles having been created and loaded with at least one element selected from corrosion-inhibiting functional molecules and corrosion-inhibiting functional nano-objects, by a method having non-dissociable nebulization-heating steps that are continuous in a single reactor. ... Centre National De La Recherche Scientifique

11/16/17 / #20170327625

Compositions comprising a polymeric network

The present invention relates to a composition comprising a polymeric network having at least one unit of formula (i), (ii), and/or (iii); (i) (ii) (iii) wherein said composition is obtained by contacting at least one compound a comprising at least two functions selected from the group of function of formula x—c(═o)—chr1—c(═o)—r2, —c(═o)—c—r2; or —c(═o)—cr1═cr2—nr4r5; wherein at least 25% by weight of compounds a have a functionality ≦5, with % by weight relative to the total weight of compounds a; with at least one compound b comprising at least one nh2, or nh3+ groups; wherein x, r1, r2, r3, r4, r5, l1 and l2 have the same meaning as that defined in the claims. The present invention also relates to a compound comprising at least two units and at most 5 units of formula (i), (ii), and/or (iii); wherein r1, r2, r3, x, l1 and l2 have the same meaning as that defined in the claims. ... Centre National De La Recherche Scientifique

11/16/17 / #20170327218

Light unmanned vertical take-off aircraft

A light unmanned vertical take-off aircraft includes at least two fixed coplanar propulsion devices and at least one wing providing the lift for the drone. The coplanar propulsion devices and the wing are each laid out on the frame of the drone so that the plane of the profile chord line of the wing is substantially parallel to the plane defined by the two coplanar propulsion devices. ... Centre National De La Recherche Scientifique

11/16/17 / #20170326246

Conjugated molecules comprising a peptide derived from the cd4 receptor coupled to an anionic polypeptide for the treatment of aids

This invention relates to a conjugated molecule comprising a peptide derived from the cd4 receptor coupled to an organic molecule by means of a linker as well as a process for its preparation. Said organic molecule comprises a 5 to 21 amino acid anionic polypeptide. ... Centre National De La Recherche Scientifique

11/09/17 / #electronic power device comprising:

Centre National De La Recherche Scientifique

. . ... Centre National De La Recherche Scientifique

11/09/17 / #20170323049

Interaction parameters for the input set of molecular structures

The present invention relates to a method for modeling the geometric structure of the interface of receptor-ligand complexes, a method for modeling the interaction between a receptor and a ligand in receptor-ligand complexes, a method for determining a scoring vector w which is a mathematical vector quantifying and/or qualifying the interaction of a geometric structure of the interface of a receptor-ligand complex, a method for determining the binding affinity or binding free energy of a position of a ligand relative to a receptor in one or more receptor-ligand complexes, and a method for ranking the binding affinity or binding free energy of spatial positions of a ligand relative to a receptor in one or more receptor-ligand complexes.. . ... Centre National De La Recherche Scientifique

11/09/17 / #20170321185

Efficient production of oligosaccharides using metabolically engineered microorganisms

The present invention relates to the enzymatic synthesis of oligosaccharides, particularly, sialylated oligosaccharides comprising the carbohydrate moieties of the gangliosides gm3, gd3, and g.. . ... Centre National De La Recherche Scientifique

11/09/17 / #20170320951

Methods for diagnosing and treating cd1d restricted gamma/delta t cell lymphomas

Methods for diagnosing and treating cd1d-restricted gamma/delta t cell lymphomas are disclosed. In particular, the present disclosure relates to a method for diagnosing a t cell lymphoma as a cd1d-restricted gamma/delta t cell lymphoma in a patient in need thereof including i) detecting the presence of cd1d restricted gamma/delta t lymphoma cells in a cell lymphoma sample obtained from the patient and ii) concluding that the t cell lymphoma is a cd1d-restricted gamma/delta t cell lymphoma when the presence of cd1d restricted gamma/delta t cells is detected in the sample. ... Centre National De La Recherche Scientifique

11/09/17 / #20170320811

Process for forming amine by direct amination reaction

Providing a process for forming an amine, such as a primary, a secondary or a tertiary amine, via the direct amination of an alcohol using a catalyst comprising at least a palladium compound on a support comprising cerium oxide.. . ... Centre National De La Recherche Scientifique

11/09/17 / #20170319681

Lentiviral vector-based japanese encephalitis immunogenic composition

The present invention relates to a lentiviral vector-based japanese encephalitis (je) immunogenic composition. The present invention is directed to a recombinant lentiviral vector expressing the precursor of membrane (prm) and the envelope (e) protein, in particular glycoprotein of a japanese encephalitis virus (jev) or immunogenic fragments thereof. ... Centre National De La Recherche Scientifique

10/26/17 / #20170310015

Method for generating high-power electromagnetic radiation

The invention relates to a method and a device for generating high-power electromagnetic radiation. A transmission antenna of a transmission device capable of emitting an electromagnetic transmission wave is arranged in a reverberation cavity comprising openings. ... Centre National De La Recherche Scientifique

10/26/17 / #20170309738

Vertically structured power transistor with trench supply electrode

The invention relates to a vertically structured power transistor, such as a vd-mos or an igbt, having a cell comprising: two symmetrical source layers (308), preferably n+ doped, which extend from a front surface (312) of the semiconductor substrate; a well layer (307), preferably p doped, comprising an area having a higher doping concentration (307b) that extends from one source layer to the other; a source/well np junction (j3) between the source layer and the well layer. According to the invention, a cathode formed on the front surface (312) of the semiconductor substrate has a trench portion (309) with a bottom (313) that extends into the area having a higher doping concentration (307b) of the well layer (307) to a certain depth away from the source/well np junction (j3).. ... Centre National De La Recherche Scientifique

10/26/17 / #20170307041

Non-linear dynamic absorber and use thereof for acoustic insulation

A building element includes a sheet of a rigid material and at least one nonlinear energy sink including a blade with two end parts and a nonlinear spring function intermediate part, a mass fixed to the nonlinear spring function intermediate part of the blade, and a fixing element allowing the two end parts of the blade to be fixed to a solid support in such a way that the nonlinear spring function intermediate part can oscillate about its position of equilibrium or its positions of equilibrium. The nonlinear energy sink is fixed rigidly to the sheet by the fixing element. ... Centre National De La Recherche Scientifique

10/26/17 / #20170306012

Monoclonal antibodies to progastrin and their uses

The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. ... Centre National De La Recherche Scientifique

10/26/17 / #20170306011

Monoclonal antibodies to progastrin and their uses

The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. ... Centre National De La Recherche Scientifique

10/26/17 / #20170304792

Device for synthesising and studying compounds under controlled temperatures and pressures

A device for synthesising and studying compounds under controlled temperatures and pressures includes: a body delimiting a vacuum chamber including temperature-regulation means and vacuum-application means, and having one or more viewing windows enabling the inside of the chamber to be observed from the outside; temperature-regulation means that are intended for regulating the temperature inside the vacuum chamber; and vacuum-application means that are intended for regulating the pressure in the vacuum chamber; wherein it includes, inside the vacuum chamber, a sealed structure delimiting a sealed chamber having one or more viewing window facing said one or more windows in said body, and at least one pipe that is in fluid communication firstly with the inside of said sealed chamber and secondly with an outlet that is made in the body and provided in order to be connected to one or more sources of gas for synthesising said compound or sample.. . ... Centre National De La Recherche Scientifique

10/26/17 / #20170304118

Device and method for cutting a cornea or crystalline lens

The invention relates to a device (1) for cutting human or animal tissue, such as a cornea (3), or a crystalline lens, said device comprising a femtosecond laser (2) that can emit a l.a.s.e.r. Beam (4) in the form of impulses, and means for directing and focusing said beam onto or into the tissue for the cutting thereof as such. ... Centre National De La Recherche Scientifique

10/12/17 / #20170294025

Method for identifying the anisotropy of the texture of a digital image

A method for determining an extent of anistropy of texture of an image in a manner that avoids inaccuracies arising from interpolation.. . ... Centre National De La Recherche Scientifique

10/12/17 / #20170292317

Active glazing system

An active glazing system (100) includes a double glazing, with two transparent plates (1a, 1b) that together delimit an intermediate volume (2) filled with gas. The system further includes a control device (10) that is capable of producing a transition in a volatile compound present in the intermediate volume, between a dry vapor state and a supersaturated vapor state of the volatile compound. ... Centre National De La Recherche Scientifique

10/05/17 / #the application concerns means for determining the stage of hepatic tissue damage, in particular the hepatic fibrosis score of subjects infected with one or more hepatitis viruses. in particular, the means of the invention involve measuring the levels of expression of selected genes, said selected genes being:

Centre National De La Recherche Scientifique

. . ... Centre National De La Recherche Scientifique

10/05/17 / #20170285012

Device for real-time in vivo molecular analysis

The invention relates to a biological material molecular analysis device characterized in that it includes:—a laser (34) optionally using an optical parametric oscillator (opo), configured to emit a wavelength between 2.5 ym and 12 put, said configured laser (34) being intended to ablate said biological material by ejecting charged and/or uncharged particles;—a mass spectrometer (31); and—a probe (s, 10) comprising at least one first analysis fiber (a, 14), connected to the laser (34), and a transfer tube (t, 21), connected to the mass spectrometer (31).. . ... Centre National De La Recherche Scientifique

10/05/17 / #20170283466

Method for preparing multiple antigen glycopeptide carbohydrate conjugates

The present invention relates to a method for preparing carbohydrate t cell epitope conjugates of formula (i): m(t-b)n (i) wherein m, t, b and n ore as defined in claim 1.. . ... Centre National De La Recherche Scientifique

09/28/17 / #20170275415

Fatty acid polyester derivatives of polyglycosides

Fatty acid polyester derivatives of polyglycosides formed from a polyol having between 2 and 10 hydroxy functions, the 2 hydroxy functions or at least 2 of these hydroxy functions being bound to the anomeric carbon of a reducing carbohydrate that is identical or different for each hydroxy group and selected from the monosaccharides and disaccharides, in which at least one of the other hydroxy groups of the monosaccharide or the disaccharide is esterified by a lipid derivative bearing at least one double bond optionally originating from a vegetable or animal oil, from a mixture of vegetable or animal oils, the double bond or the at least one of the double bonds of the lipid derivative being functionalized by a group selected from the epoxy, amine, alcohol and acid groups, and use thereof in particular in reaction formulations for the production of polymer materials.. . ... Centre National De La Recherche Scientifique

09/14/17 / #20170263993

Filtering device and filtering assembly having an electrically conducting strip structure

A filter device includes a transmission line formed by an electrically conducting strip printed on a surface of an electrically insulating substrate, the conducting strip having two ends respectively forming the two sole input and output connection ports of the filter device, and a plurality of resonators, each resonator including an electrically conducting strip printed on the surface of the substrate. The conducting strip of each resonator has a first end coupled to the transmission line and at least one second end that is free or connected to a ground so as to create an effective fundamental resonant wavelength specific to each resonator. ... Centre National De La Recherche Scientifique

09/14/17 / #20170261414

Method for characterizing the cracking mechanism of a material from the fracture surface thereof

The disclosed method includes, from a topographic map showing, for a set of points {x} located in a midplane of the fracture surface, a height of the fracture surface h relative to the midplane: a step of determining, for each point x on the topographic map, a quantity ω∈ representative of an average difference in height)iδxi≦∈ between the height h of the fracture surface at point x in question and the height h of the fracture surface at one or more points {x+δx} located inside a circle of radius ∈ centered on point x in question, a step of determining, according to a test distance δr, a spatial correlation function c∈ representing a spatial correlation between points {x} and points {x+δx} such as iδxi=δr, and a step of determining a correlation length ξ from the spatial correlation function c∈.. . ... Centre National De La Recherche Scientifique

09/14/17 / #20170260329

New phenolic polymers and preparation processes thereof

The present invention concerns the use of a compound having the following formula (i), for the preparation of a polymer. The present invention also concerns the polymers obtained from polymerization of compound of formula (i), and their processes of preparation.. ... Centre National De La Recherche Scientifique

09/07/17 / #a laser device for generating an optical wave including at least two frequencies, such laser device including:

Centre National De La Recherche Scientifique

. . ... Centre National De La Recherche Scientifique

09/07/17 / #20170256531

Soi integrated circuit equipped with a device for protecting against electrostatic discharges

A protection device for protecting an ic against electrostatic discharge includes a buried insulant layer having a thickness that is no greater than fifty nanometers with bipolar transistors arranged thereon, one of which is npn and the other of which is pnp. A base of one merges with a collector of the other. ... Centre National De La Recherche Scientifique

09/07/17 / #20170256351

Skyrmion generation system

Disclosed is a system (10) for generating skyrmions, including: a gun (12) including a wall-forming region (14) made from a first material, the region (14) defining an outer space (16) made from a second material different from the first material and an inner space (18) made from a third material different from the first material, the second material and the third material being magnetic materials; and a magnetisation reversal device (26) that can reverse the magnetisation at the interface between the region (14) and the inner space (18).. . ... Centre National De La Recherche Scientifique

09/07/17 / #20170253901

Method for producing a compound of the sterol biosynthesis pathway in a eukaryotic organism

The invention concerns a method for producing a compound of interest of the sterol biosynthesis pathway in a eukaryotic organism or a derivative of a compound of the sterol biosynthesis pathway in said eukaryotic organism, in particular a sterol. This method comprises a step for the in vitro culturing of cells of said eukaryotic organism modified to express or overexpress a defensin, in a culture medium suitable for the development of said cells and containing at least one element chosen from the transition metals, lead and selenium, at a concentration greater than or equal to the concentration of said element that is necessary for inducing the overproduction of said compound of interest by said cells.. ... Centre National De La Recherche Scientifique

09/07/17 / #20170253884

Use of micropeptides in order to stimulate mycorrhizal symbiosis

A method for promoting mycorrhizal symbiosis between a plant and a fungus includes using micropeptides (peptides encoded by micrornas or “mipeps”).. . ... Centre National De La Recherche Scientifique

09/07/17 / #20170253547

Process for hydroxylation of aromatic compounds, hydroxylation catalyst and process for preparing same

The present invention relates to a process for hydroxylation of a compound of formula (i) by reacting the compound of formula (i) with an oxidizing agent, in the presence of a titanium silicalite zeolite prepared by crystallization preceded by a maturing step. The present invention also relates to a titanium silicalite zeolite and to the process for preparing same.. ... Centre National De La Recherche Scientifique

09/07/17 / #20170252744

Method for handling microdrops which include samples

A method for handling, in a microfluidic system, microdrops which include samples, including the steps of forming, in an oil, microdrops of an aqueous solution containing a sample, the oil and/or the aqueous solution containing a sample including a gelling agent; trapping the microdrops by means of surface-tension traps pre-arranged in a trapping area; and at least partially gelling the oil in the trapping area and/or at least partially gelling the trapped microdrops.. . ... Centre National De La Recherche Scientifique

09/07/17 / #20170252718

Heat insulation material based on aerogel

A heat insulation material is provided that is produced by drying a fibrous matrix impregnated with a solution of pseudo-peptides of formula (i), wherein: r is a side-chain of a natural or synthetic amino acid , r1 is either a linear or branched (c1-c3)alkyl group, or a linear or branched (c1-c3)alcoxy group, or an aryl group, or an aryl(c1-c3)alkyl group, or an aryloxy group, or a saturated or unsaturated heterocycle, n=1 or 2, and a is an aromatic or heteroaromatic group with at least one cycle.. . ... Centre National De La Recherche Scientifique

08/31/17 / #20170248582

Mixed spheroids of melanocytes and keratinocytes

The present invention concerns the development of a model to evaluate active substances targeting the epidermis. It more particularly relates to the preparation of mixed spheroids of melanocytes and keratinocytes reproducing cell interactions occurring in the epidermis, to the spheroids as such and to the uses thereof.. ... Centre National De La Recherche Scientifique

08/31/17 / #20170246631

Microfluidic device with one microchannel for multiple detection

The present invention relates to a microfluidic device (2) comprising a support part (21) and a cover part (22) defining together a microchannel (5), said microchannel (5) having a surface, said surface comprising:—a first area (9) which is grafted with a first ligand, and—at least a second area (10) which is distinct from the first area (9) and which is grafted with a second ligand which is different from the first ligand, wherein each ligand is capable of binding to a target, the targets being different from each other. The present invention further relates to a microfluidic detection system comprising the said microfiuidic device, a reservoir adapted for containing a sample to be analysed and a detection device for detecting and quantifying the targets. ... Centre National De La Recherche Scientifique

08/31/17 / #20170246098

Skin whitening peptide agents

The present invention provides new peptides useful as skin whitening agents and their uses in cosmetic or therapeutic applications.. . ... Centre National De La Recherche Scientifique

08/24/17 / #20170245059

Electroacoustic transducer, and associated assembly and system

Disclosed is an acoustic transducer for converting a sound signal into an electric signal, including a mobile element movable under the effect of the sound signal, a fixed element opposite the mobile element, a recess, and a dissipative element between the mobile and fixed elements. The coupled system has a natural frequency corresponding to a resonance frequency of the transducer set at maximum sensitivity. ... Centre National De La Recherche Scientifique

08/24/17 / #20170240937

New process for preparing biphenyl compounds

The present invention relates to a process for preparing a compound having the formula (i), said process comprising the following steps: a) the addition of an oxygen source into a solution of a compound of formula (ii), in a water-miscible solvent, b) the addition of a laccase in the solution obtained after step a); and c) the possible recovering of the compound of formula (i) thus obtained.. . ... Centre National De La Recherche Scientifique

08/24/17 / #20170240869

Clostridium acetobutylicum strains unable to produce hydrogen and useful for the continuous production of chemicals and fuels

The present invention relates to a new strain of clostridium acetobutylicum modified to be unable to produce hydrogen and its use for the continuous production of bulk chemicals such as lactate, 1,3-propanediol, ethanol, butanol, isobutanol, 1,3-butanediol, acetate, acetone, isopropanol, 3-hydroxy-3-methylbutyrate and isobutene at high yield.. . ... Centre National De La Recherche Scientifique

08/24/17 / #20170239242

Methods and pharmaceutical compositions for the treatment of fibrosis

The present invention relates to methods and pharmaceutical compositions for the treatment of fibrosis. In particular, the present invention relates to a method of treating fibrosis in a subject in need thereof comprising administering the subject with a therapeutically effective amount of at least one monoacylglycerol lipase (mgl) inhibitor.. ... Centre National De La Recherche Scientifique

08/17/17 / #20170237988

Decoder, method and system for decoding multimedia streams

Decoder, system and method for decoding multimedia data at the level of a terminal by managing the energy available for decoding comprising a decoder of the multimedia data, characterized in that said decoder comprises at least one low-consumption decoding chain comprising an activation module suitable for activating a first low-consumption decoding chain or loop filter and a low-consumption interpolation chain as a function of at least one parameter representative of constraints of user energy and/or of the mobile terminal and of one or more metadata md associated with a decoding complexity and/or with a decoding energy.. . ... Centre National De La Recherche Scientifique

08/17/17 / #20170233646

Aqueous composition containing suspended zno particles

The invention relates to an aqueous composition comprising a suspension of zno particles and a polymer stabiliser containing carboxylic acid functions and carboxylic acid salt functions.. . ... Centre National De La Recherche Scientifique

08/17/17 / #20170233469

Prophylaxis of colorectal and gastrointestinal cancer

The present disclosure provides methods and compositions useful for preventing gastrointestinal and/or colorectal cancer in animals, including humans, having pre-cancerous adenomatous polyps. The present disclosure provides compositions comprising anti-pg antibodies suitable for use in the methods of the disclosure. ... Centre National De La Recherche Scientifique

08/17/17 / #20170233342

New derivatives of indole for the treatment of cancer, viral infections and lung diseases

The present invention relates to a new class of indole derivatives, having a particular mklp2 inhibition profile and useful as a therapeutic agent, in particular for the treatment of cancer, viral infections and lung diseases.. . ... Centre National De La Recherche Scientifique

08/10/17 / #the present invention relates to method for chiral resolution of chiral species contained in a liquid placed in a cell formed by an inner wall and an outer wall surrounding the inner wall over at least a portion of the inner wall, each of the outer and inner walls being a solid of revolution about a longitudinal axis, the outer and inner walls being coaxial to one another, the method comprising:

Centre National De La Recherche Scientifique - Cnrs

. . ... Centre National De La Recherche Scientifique

08/10/17 / #20170227532

Method for producing a capture phase for the detection of a biological target, and associated detection methods and kits

The invention provides a novel method of preparing a capture phase for detecting and/or quantifying a target biological entity, said capture phase including a biological ligand for the biological entity, said biological ligand being covalently bonded to an amphiphilic polymer and being immobilized on a solid support, the method being characterized in that the biological ligand is immobilized on the solid support by bringing the solid support into contact with a dispersion of micelles formed by a plurality of chains of the amphiphilic polymer, said micelles carrying a plurality of molecules of the biological ligand on the surface thereof. The invention also provides corresponding capture phases and associated detection methods and kits.. ... Centre National De La Recherche Scientifique

08/10/17 / #20170227506

Method and device for concentrating molecules or objects dissolved in solution

A method for concentrating electrically charged objects in a non-newtonian liquid medium comprises: feeding a sample containing electrically charged objects into a channel having a flow axis, a first transverse cross-section orthogonal to the flow axis, and at least one second transverse cross-section orthogonal to the flow axis, one dimension of the second cross-section being less than the corresponding dimension of the first cross-section; and applying a hydrodynamic flow in a direction of the channel together with the application, in the opposite direction, of an electric field in the channel, thus making it possible to move the electrically charged objects in the channel along the flow axis from the first cross-section to the second cross-section, stop the objects, and concentrate the objects in at least one area upstream from the second transverse cross-section.. . ... Centre National De La Recherche Scientifique

08/10/17 / #20170224526

Device for cold or hot thermal stimulation and method for controlling and adjusting same

The present invention relates to a control and command method for a device for thermal stimulation of animal or human tissue (1), said method being characterised in that it includes: determining a neutral temperature applied to the tissue (1), thermally adjusting the neutral temperature by activating a control loop, determining a cold or hot thermal stimulation temperature to be applied to the tissue (1), in alternation with the neutral temperature; determining a duration and a frequency of the thermal stimulations; in the case of an instruction to initiate the stimulation temperature by activating a control loop and by deactivating the control loop on the neutral temperature; and synchronising a physiological recording with the thermal stimulation.. . ... Centre National De La Recherche Scientifique

08/03/17 / #20170217832

Transparent substrate, in particular a glass substrate, coated with at least bifunctional porous layer, manufacturing method and uses thereof

A transparent glass or ceramic or glass-ceramic substrate, coated with a functional layer or with a stack of at least two functional layers, the functional layer or at least one of the functional layers of the stack being porous and made of an inorganic material m1, wherein the or at least one of the porous functional layer(s) of inorganic material m1 has, at the surface of at least one portion of the pores thereof, at least one inorganic material m2 different from m1.. . ... Centre National De La Recherche Scientifique

07/27/17 / #the present invention relates to a method of testing whether a patient suffering from arge b-cell lymphoma will respond or not to a dna repair pathway inhibitor comprising: i) determining the expression level (eli) of several genes gi-gn selected from table a in a biological sample obtained from said patient comparing the expression level (eli) determined at step i) with a predetermined reference level (elri) iii) calculating the dna repair score trough the following formula (i), wherein βi represent the regression β coefficient reference value for the gene gi and ci=1 if the expression of the gene gi (eli) is higher than the predetermined reference level (elri) or ci=−1 if the expression of the gene (eli) is lower than or equal to the predetermined reference level (elri) iv) comparing the score dnars determined at step iii) with a predetermined reference value dnarsr v) and concluding that the patient will respond to the treatment when the dnars score is higher than the predetermined reference value dnarsg or concluding that the patient will not respond to the treatment when the dnars score is lower than the predetermined reference value dnarsr.

Centre National De La Recherche Scientifique (cnrs

. . ... Centre National De La Recherche Scientifique

07/27/17 / #20170213868

Semiconducting pixel, matrix of such pixels, semiconducting structure for the production of such pixels and their methods of fabrication

A pixel comprises three adjacent sub-pixels, formed by respective stacks of semi-conducting layers wherein: each sub-pixel comprises a first active layer, adapted for emitting a light at a first wavelength when an electric current passes through it; another sub-pixel comprises a second active layer, adapted for emitting a light at a second wavelength greater than the first wavelength; another sub-pixel comprises a third active layer, adapted for emitting a light at a third wavelength greater than the first wavelength and different from the second wavelength; at least one from among the second and third active layers being adapted for emitting light when it is excited by the light at the first wavelength emitted by the first active layer of the same sub-pixel. Semi-conducting structure and methods for the fabrication of such a pixel are provided.. ... Centre National De La Recherche Scientifique

07/27/17 / #20170212702

Data back-up in an asynchronous circuit

An asynchronous circuit including an asynchronous pipeline including two or more stages, each stage having: a buffering circuit for temporarily storing data to be transferred from one stage to the next based on a handshake protocol, the buffering circuit including a non-volatile memory; and a data presence detection circuit adapted to generate a data presence detection value indicating whether or not data is stored by the buffering circuit; and a control circuit adapted to perform a data back-up operation by independently controlling each buffering circuit to back-up the data it stores to its non-volatile memory based on the corresponding data presence detection value.. . ... Centre National De La Recherche Scientifique

07/27/17 / #20170211119

In vivo production of a recombinant carotenoid-protein complex

The present invention relates to a method for producing a carotenoid-protein complex in vivo comprising the steps of transforming of prokaryote cell with genes involved in carotenoid synthesis and with a gene encoding an apo-carotenoprotein; culturing said prokaryote cells such as to induce sequential genes expression, isolating and purifying the carotenoid-protein complex.. . ... Centre National De La Recherche Scientifique

07/27/17 / #20170211080

Use of micropeptides for promoting plant growth

The present invention relates to the use of micropeptides (peptides encoded by micrornas or “mipeps”) for promoting plant growth.. . ... Centre National De La Recherche Scientifique

07/27/17 / #20170210700

3-aryl propiolonitrile compounds for thiol labeling

The present invention relates to a process for labeling compounds comprising thiol moieties with 3-arylpropiolonitrile compounds, to 3-arylpropiolonitrile compounds substituted with tag moieties and to specific 3-arylpropiolonitrile linkers.. . ... Centre National De La Recherche Scientifique

07/27/17 / #20170209597

Capped and uncapped rna molecules and block copolymers for intracellular delivery of rna

The present invention relates to the use of at least one tetra functional non-ionic amphiphilic block copolymer as a vehicle for capped or uncapped mrna for intracellular delivery for gene therapy.. . ... Centre National De La Recherche Scientifique

07/27/17 / #20170209086

Portable device for measuring physical parameters associated with the ankle joint of a subject, and frame of such a device

The invention relates to a portable device (1) comprising a frame (2) which comprises a receptacle (9) that is intended to receive a subject's foot and is mounted in a pivoting manner on the frame, a means (10, 13) for temporarily locking the receptacle in a first position, the device comprising means (19) for determining a torque exerted on the receptacle, means (20) for determining an angular displacement of the receptacle relative to the frame, and means (22) for determining an angular acceleration of the receptacle during an angular displacement of the receptacle, at least the locking means and the means for determining a torque being arranged in the frame behind the receptacle when the receptacle opening faces the subject. The invention also relates to a frame of such a device.. ... Centre National De La Recherche Scientifique

07/20/17 / #20170207400

Molecules presenting dual emission properties

The present invention concerns compound of formula (i): wherein: a represents an electron-withdrawing group; d represents an electron-donating group; x is selected from the group consisting of: o, s and nr, wherein r is selected from the group consisting of: h, an alkyl group preferably comprising from 1 to 20 carbon atoms, an aryl group preferably comprising from 6 to 22 carbon atoms, and a heteroaryl group; n is an integer from 1 to 4; m is an integer from 1 to 6, preferably from 1 to 4; formula (ii) represents a condensed bicyclic aromatic radical comprising from 6 to 22 carbon atoms, and from 1 to 3 heteroatom(s) selected from the group consisting of: n, s and o; the oh group being in ortho position of the condensed bicyclic aromatic radical relative to the formula (iii) radical. The present invention also concerns its uses, and light devices comprising them.. ... Centre National De La Recherche Scientifique

06/22/17 / #an electronic device with a circuit for supplying electric power, with a variable capacitor, by alternating mechanical movement. the supply includes, in the form of passive components and without synchronizing structure:

Centre National De La Recherche Scientifique

. . ... Centre National De La Recherche Scientifique

06/22/17 / #20170176417

Method and pharmaceutical composition for use in the treatment of neurodegenerative disorders

The invention relates to compounds which activate the basigin signalling pathway, preferably agonists of basigin, for the treatment of neurodegenerative disorders.. . ... Centre National De La Recherche Scientifique

06/22/17 / #20170175107

Methods for selecting binders by phage display and masked selection

The present invention relates to methods for selecting binders by phage display and masked selection. More particularly, the present invention relates to a method for selecting a plurality of binders specific for at least one relevant target comprising screening a phage binder library of binders against the relevant target in presence of a plurality of binders obtained from a library of binders directed against at least one irrelevant target and positively selecting the binders that are specific for the at least one relevant target.. ... Centre National De La Recherche Scientifique

06/22/17 / #20170174761

Monoclonal antibodies to progastrin and their uses

The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. ... Centre National De La Recherche Scientifique

06/22/17 / #20170174669

Pochoxime conjugates useful for the treatment of hsp90 related pathologies

The present invention includes novel derivatives, analogs, and intermediates of the natural products radicicol, pochonins, pochoximes, and their syntheses. The present invention also provides a pharmaceutical composition comprising the present compound and the use of the compound as inhibitors of kinases and of the enzyme family known as heat shock protein 90 (hsp90).. ... Centre National De La Recherche Scientifique

06/22/17 / #20170174644

Nat10 modulators for treating or preventing laminopathies, aging and cancer

The invention relates to compounds in the treatment or prevention of disorders associated with lamin a and/or lamin c depletion or lmna mutations, such as laminopathy, premature ageing disorders, normal ageing and cancer (such as a cancer characterised by low levels of lmna expression).. . ... Centre National De La Recherche Scientifique








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