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Cornell University
Cornell University Cornell Center For Technology Enterprise x26 Commercialization cctec
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Cornell University A New York Corporation
Cornell University Cornell Center For Technology
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Cornell University The Trustees Of Columbia University In The City Of New York

Cornell University patents


Recent patent applications related to Cornell University. Cornell University is listed as an Agent/Assignee. Note: Cornell University may have other listings under different names/spellings. We're not affiliated with Cornell University, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "C" | Cornell University-related inventors


 new patent  Method for treating idiopathic pulmonary fibrosis

Aspects of the disclosure relate to a method for treating idiopathic pulmonary fibrosis (IPF) in a patient with N-acetylcysteine (NAC) comprising administering NAC to a patient after a sample from the patient has been genotyped and determined to be any one of: a) homozygous or heterozygous for a thymine at... Cornell University

 new patent  Nanoparticle immunoconjugates

Disclosed herein are nanoparticle immunoconjugates useful for therapeutics and/or diagnostics. The immunoconjugates have diameter (e.g., average diameter) no greater than 20 nanometers (e.g., as measured by dynamic light scattering (DLS) in aqueous solution, e.g., saline solution). In certain embodiments, the conjugates are silica-based nanoparticles with single chain antibody fragments attached... Cornell University

 new patent  Ultrasmall nanoparticles and methods of making and using same

An aqueous synthesis methodology for the preparation of silica nanoparticles (SNPs), core-shell SNPs having, for example, a size of 2 to 15 nm and narrow size-dispersion with size control below 1 nm, i.e. at the level of a single atomic layer. Different types of dyes, including near infrared (NIR) emitters,... Cornell University

Lithium containing nanofibers

Lithium-containing nanofibers, as well as processes for making the same, are disclosed herein. In some embodiments described herein, using high throughput (e.g., gas assisted and/or water based) electrospinning processes produce nanofibers of high energy capacity materials with continuous lithium-containing matrices or discrete crystal domains.... Cornell University

Method of non-uniform wavelet bandpass sampling

A compressed sensing method based on non-uniform wavelet bandpass sampling. A K-sparse signal of interest is projected onto a sequence of waveforms succeeding one another at the bandpass sampling rate, the waveforms belonging to an overcomplete dictionary, the parameters of the waveforms depending on the characteristics of the bands of... Cornell University

Cosmetic compositions containing quinones and their topical use on skin and hair

Described are compositions containing quinones that show activity in enhance DNA repair and/or prevent damage to DNA. The quinones are thymoquinone, lapachol, myrtucommulone C, or mixtures thereof, and can be formulated into cosmetic compositions for topical administration to a subject in need thereof. The cosmetic compositions can also include sunscreens,... Cornell University

Carbonaceous metal/ceramic nanofibers

Provided herein are nanofibers and processes of preparing carbonaceous nanofibers. In some embodiments, the nanofibers are high quality, high performance nanofibers, highly coherent nanofibers, highly continuous nanofibers, or the like. In some embodiments, the nanofibers have increased coherence, increased length, few voids and/or defects, and/or other advantageous characteristics. In some... Cornell University

Modified cellulosic compositions having increased hydrophobicity and processes for their production

The disclosure provides a composition comprising a modified cellulosic surface having aliphatic fatty acid molecules and amine-silica particles that are covalently bonded to cellulose fibers of the cellulosic surface. Also disclosed is a composition comprising a modified cellulosic surface including low surface energy molecules and amine functionalized nanotubes decorated with... Cornell University

Lithium metal anode comprising langmuir-blodgett films as an artificial solid electrolyte interface layer, lithium metal battery comprising the same, and preparation method thereof

Provided is a lithium metal anode comprising a Langmuir-Blodgett films as an artificial solid electrolyte interface layer, a lithium metal battery comprising the same, and a preparation method thereof. Various ultra-thin film layers made of carbon and ceramic are formed on the surface of the LiM to serve as a... Cornell University

Methods for preventing or treating metabolic syndrome

The invention provides methods of preventing or treating metabolic syndrome in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof.... Cornell University

Direct assay for allosteric modulators of glutaminase

The present technology relates to GLS proteins that have a phenylalanine to tryptophan substitution at the position corresponding to residue 322 of human GAC, and methods of using such proteins to screen for compounds that bind to the activation loop of GLS and/or modulate glutaminase activity of GLS.... Cornell University

Systems and methods for mr microscopy analysis of resected tissue

The present disclosure discusses systems and methods for imaging tissue. The system can reduce the amount of vibrations that are transmitted from a magnetic resonance imaging device to a tissue sample. The system can include a stabilization platform with at least one vibration dampener coupled towards either end of the... Cornell University

Method and straightening and flattening the side wall of a body lumen or body cavity so as to provide three dimensional exposure of a lesion or abnormality within the body lumen or body cavity, and/or for stabilizing an instrument relative to the same

the deployable hoop expander being configured so as to be transitionable between (i) a reduced cross-sectional configuration, and (ii) an expanded cross-sectional configuration, whereby the deployable hoop expander can be configured in its reduced cross-sectional configuration for easy insertion into a body lumen, and it can thereafter be re-configured into... Cornell University

Multimodal silica-based nanoparticles

The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1... Cornell University

Porous cyclodextrin polymeric materials and methods of making and using same

A nucleophilic substitution reaction to crosslink cyclodextrin (CD) polymer with rigid aromatic groups, providing a high surface area, mesoporous CD-containing polymers (P-CDPs). The P-CDPs can be used for removing organic contaminants from water. By encapsulating pollutants to form well-defined host-guest complexes with complementary selectivities to activated carbon (AC) sorbents. The... Cornell University

Hierarchical magnetic nanoparticle-enzyme mesoporous assemblies embedded in macroporous scaffolds

A hierarchical catalyst composition comprising a continuous or particulate macroporous scaffold in which is incorporated mesoporous aggregates of magnetic nanoparticles, wherein an enzyme is embedded in mesopores of the mesoporous aggregates of magnetic nanoparticles. Methods for synthesizing the hierarchical catalyst composition are also described. Also described are processes that use... Cornell University

Elevated psma identifies lethal prostate cancers

Prostate cancer (PC) is an entity that encompasses different types of tumors, including adenocarcinomas and non-adenocarcinomas. Adenocarcinomas and non-adenocarcinomas respond to, and therefore should be treated, with different treatments. Even within the adenocarcinomas, the lethality of tumors is highly variable, from low risk/indolent/non-life threatening to high risk/lethal. The inability to... Cornell University

Machine vision with dimensional data reduction

A method is described that includes receiving raw image data corresponding to a series of raw images, and processing the raw image data with an encoder of a processing device to generate encoded data. The encoder is characterized by an input/output transformation that substantially mimics the input/output transformation of at... Cornell University

Subunit vaccine delivery platform for robust humoral and cellular immune responses

The present invention relates to a probiotic cell transformed with a construct suitable to overexpress and display on the surface of the probiotic cell a fusion protein comprising at least a portion of a transport protein coupled to at least a portion of one or more antigenic proteins or peptides.... Cornell University

Substituted 3-hydroxy-delta-lactones from epoxides

Catalysts and methods for the carbonylation of epoxides to substituted 3-hydroxy-δ-lactones and β-lactones are disclosed.... Cornell University

Universal molecular processor for precision medicine

The present invention is directed to a device that comprises a biomolecular processor and one or more nanotubes. Each biomolecular processor comprises a bioreactor chamber defined by a solid substrate, a plurality of spaced support structures within said bioreactor chamber and attached to the solid substrate, and one or more... Cornell University

I domain chimeric antigen receptor specific to icam-1

The present invention relates to chimeric antigen receptors (CARs) specific to ICAM-1 comprising I domain of the αL subunit of human lymphocyte function-associated antigen 1 (LFA-1). The invention particularly relates to CARs comprising human I domains having different affinities (1 mM to 1 nM Kd) to ICAM-1. CAR T cells... Cornell University

Transduced t cells expressing human sstr2 and application thereof

The present invention is directed to transduced T cells expressing at least 100,000 molecules of human somatostatin receptor 2 (SSTR2), which improves PET/CT imaging sensitivity. The present invention is also directed to transduced T cells expressing SSTR2 and chimeric antigen receptor (CAR). In one embodiment, the CAR is specific to... Cornell University

Mindless technologies to subtly influence behavior

Persuasive technologies aim to influence user's behaviors. In order to be effective, many of the persuasive technologies developed so far relies on user's motivation and ability, which is highly variable and often the reason behind the failure of such technology. Mindless Computing, a new approach to persuasive technology design, is... Cornell University

Methods to enhance cell-mediated immunity

This disclosure provides a method for enhancing cell-mediated immunity in individuals with disorders such as cancer or infection that involves administering an inhibitor of GOLPH2 to the individuals. For example, inhibition of GOLPH2 increases the endogenous production of IL-12.... Cornell University

Device for terahertz signal generation and transmitter

A high-power transmitter with a fully-integrated phase Iocking capability is disclosed and characterized. Also provided herein is a THz radiator structure based on a return-path gap coupler, which enables the high-power generation of the disclosed transmitter, and a self-feeding oscillator suitable for TS use with the transmitter.... Cornell University

Compositions and methods using il-8 to improve milk production and reproductive health in mammals

The present disclosure provides compositions and methods for improving reproductive health of mammals and increasing milk production from female mammals. The methods involve administering an effective amount of IL-8 to a female mammal such that the reproductive health of the mammal is improved, or milk production from the mammal is... Cornell University

Nanosecond-timescale low-error switching of 3-terminal magnetic tunnel junction circuits through dynamic in-plane-field assisted spin-hall effect

The disclosed technology provides various implementations of a device based on a spin Hall effect (SHE) and spin transfer torque (STT) effect. In one aspect, a device is provided to include a magnetic structure including a ferromagnetic layer having a magnetization direction that can be changed by spin transfer torque;... Cornell University

Method for rapid in vitro synthesis of bioconjugate vaccines via recombinant production of n-glycosylated proteins in prokaryotic cell lysates

Disclosed are methods, systems, components, and compositions for cell-free synthesis of glycosylated proteins. The glycosylated proteins may be utilized in vaccines, including anti-bacterial vaccines. The glycosylated proteins may include a bacterial polysaccharide conjugated to a carrier, which may be utilized to generate an immune response in an immunized host against... Cornell University

Viral vectors for prophylaxis and therapy of hemoglobinopathies

Provided are compositions and methods for inducing expression of human beta-globin in erythrocytes for use in prophylaxis and/or therapy of a hemoglobinopathy in an individual. The method generally entails introducing into CD34+ cells a polynucleotide encoding: i) a 5′ long terminal repeat (LTR) and a self-inactivating 3′ LTR; ii) at... Cornell University

Mems microtensiometer

A device for measuring a chemical potential of a fluid in a plant tissue includes a cavity disposed within a sensor body as a liquid reservoir. The cavity is configured for containing therein a liquid, and the cavity including at least one opening. At least two porous membrane layers are... Cornell University

Thin film plasmonic optical modulator

A plasmon-based optical modulator comprises a substrate, a layer of high reflectivity material disposed over the substrate, a relatively thin dielectric layer disposed over a top major surface of the layer of high reflectivity material and a plurality of graphene strips disposed in parallel across a top major surface of... Cornell University

Fitting procedural yarn models for realistic cloth rendering

An apparatus in one embodiment comprises a multi-stage processing pipeline configured to generate a procedural yarn model by fitting procedural yarn model parameters to input data comprising computed tomography measurements of one or more actual yarn samples. The apparatus further comprises an image rendering system configured to execute one or... Cornell University

Double targeted constructs to affect tumor kill

or pharmaceutically acceptable salts thereof. The present technology is especially well-suited for use in treating prostate cancer.... Cornell University

18f-labeled triazole containing psma inhibitors

or a pharmaceutically acceptable salt thereof.... Cornell University

12/21/17 / #20170362221

Inhibitors of kidney-type glutaminase, gls-1

The present invention relates generally to glutaminase inhibitors of Formula I, Formula II, or Formula III, as well as pharmaceutical compounds containing them and methods of their use.... Cornell University

12/07/17 / #20170350809

Integrated optofluidic system using microspheres

An integrated optofluidic system for trapping and transporting particles for analysis is provided comprising a planar substrate; a microfluidic channel; and a waveguide integrated with the channel. A microsphere particle in the integrated optofluidic system can act as a cavity, allowing light to circulate many thousands of times around the... Cornell University

12/07/17 / #20170352027

Authenticated data feed for blockchains

An apparatus in one embodiment comprises a processing platform having at least one processing device. The processing platform implements a trusted bridge configured for at least temporary coupling between one or more data sources and a smart contract program of a blockchain. The trusted bridge comprises a secure enclave component... Cornell University

11/30/17 / #20170342097

Methods and compositions to treat type-1 and type-2 diabetes

The present disclosure is directed to novel methods of treating type-1 or type-2 diabetes by inactivating TLR2 and TLR4 genes together in cells capable of producing insulin and/or regenerating β cells, and providing the cells to a subject in need thereof.... Cornell University

11/30/17 / #20170342447

Methods of and systems for producing caprylic acid and/or caprylate

Methods and systems to produce product compositions comprising caprylate products using chain-elongating bacteria. For example, the caprylate product in the product composition is n-caprylic acid (C8) and the n-caprylic (C8) to n-caproic (C6) acid ratio is higher than 1:1. These methods use chain elongation towards C8 rather than C6. High... Cornell University

11/23/17 / #20170335061

Isotactic polyethers and bimetallic catalysts, methods of making same, and uses thereof

Provided are compositions comprising isotactic polyethers. Methods of making isotactic polyethers, and uses thereof are also disclosed. Also provided are bimetallic complexes that can be used as catalyst. Methods of making isotactic polyethers and bimetallic complexes and uses thereof are also disclosed. For example, a racemic bimetallic (salalen)CrCl polymerization catalyst... Cornell University

11/16/17 / #20170325520

Thermochromic apparel for detecting physical exhaustion and process for preparation thereof

The present invention relates to a thermochromic garment comprising a thermochromic pigment. The present invention also relates to a process for making a thermochromic garment comprising a thermochromic pigment. The present invention further provides methods for using a thermochromic garment comprising a thermochromic pigment, including, inter alia, methods involving monitoring... Cornell University

11/16/17 / #20170327649

Films derived from two or more chemically distinct block copolymers, methods of making same, and uses thereof

Methods of making blended, isoporous, asymmetric (graded) films (e.g. ultrafiltration membranes) comprising two or more chemically distinct block copolymers and blended, isoporous, asymmetric (graded) films (e.g. ultrafiltration membranes) comprising two or more chemically distinct block copolymers. The generation of blended membranes by mixing two chemically distinct block copolymers in the... Cornell University

11/02/17 / #20170315109

Nanopore-containing substrates with aligned nanoscale electronic elements and methods of making and using same

A nanopore-containing substrate includes a substrate, a membrane on the substrate, and at least one nanoscale electronic element disposed on or embedded in the membrane. The membrane defines at least one nanopore. The nanoscale electronic element is aligned with one of the nanopores such that a shortest distance between an... Cornell University

10/26/17 / #20170304499

Injectable peripheral nerve specific hydrogel

The present invention relates to a peripheral nerve-specific hydrogel material, which is deliverable in a minimally invasive fashion, sustains the growth of neurons, and speeds recovery following surgical reconstruction.... Cornell University

10/12/17 / #20170290815

Glutaminase inhibitors

provided that if c is 1 and d is 0, then R2 is amino and R1 is optionally substituted alkyl, optionally substituted aralkyl, optionally substituted cycloalkyl, optionally substituted heteroaralkyl, optionally substituted alkylalkoxy, optionally substituted alkylaryloxy, optionally substituted aryl, optionally substituted heteroaryl, or optionally substituted heterocycloalkyl.... Cornell University

10/12/17 / #20170290953

Composite tissue-engineered intervertebral disc with self-assembled annular alignment

The present invention relates to a tissue-engineered intervertebral disc (IVD) suitable for total disc replacement in a mammal and methods of fabrication. The IVD comprises a nucleus pulposus structure comprising a first population of living cells that secrete a hydrophilic protein and an annulus fibrosis structure surrounding and in contact... Cornell University

09/28/17 / #20170273691

Method and restricting flow through an opening in the side wall of a body lumen, and/or for reinforcing a weakness in the side wall of a body lumen, while still maintaining substantially normal flow through the body lumen

heat treating said single filament, two-dimensional interim structure while it is mounted to said fixture so as to produce said device in its longitudinally-contracted, substantially three-dimensional configuration.... Cornell University

09/28/17 / #20170275343

Compositions and methods for making water-soluble integral membrane proteins

The present invention relates to a nucleic acid construct having a chimeric nucleic acid molecule comprising a first nucleic acid moiety encoding an amphipathic shield domain protein; a second nucleic acid moiety encoding an integral membrane protein; and a third nucleic acid moiety encoding a water soluble expression decoy protein,... Cornell University

09/28/17 / #20170275399

Anion-coordinating polymer electrolytes and related compositions, methods and systems

Anion-coordinating polymers comprising one or more anion-coordinating unit of Formula (I), optionally in combination with one or more cation-coordinating unit of Formula (II) and/or a linking unit of Formula (III) and related electrolytes, batteries, methods and system.... Cornell University

09/14/17 / #20170258852

Implantable therapeutic delivery system and methods thereof

The present invention relates to an implantable therapeutic delivery system, methods of treatment utilizing the implantable therapeutic delivery system, and methods of fabricating the implantable delivery system. A first aspect of the present invention is directed to an implantable therapeutic delivery system. This therapeutic delivery system comprises a substrate, an... Cornell University

09/14/17 / #20170260586

Gene expression monitoring for risk assessment of apple and pear fruit storage stress and physiological disorders

The present invention is a tool for diagnosis and prediction using biomarker-based risk assessment for chilling-related disorders of Rosaceous fruit crops including apple and pear. Provided are methodology and genes whose relative and absolute expression can accurately indicate disorder risk throughout the production and supply chain of these crops. This... Cornell University

09/14/17 / #20170262606

Health monitoring using social rhythms stability

Methods, systems, and devices are disclosed for passively monitoring a health condition of a subject using a mobile device. In some aspects, a method includes producing a set of quantitative metrics based on one or more parameters including location, movement, and sound obtained from the mobile device, where the produced... Cornell University

09/07/17 / #20170252350

Small molecule ire1-alpha inhibitors

Described herein are IRE1α in inhibitors, compositions containing such inhibitors, and methods of treatment that include administration of such compounds. Exemplary compounds are provided throughout the application.... Cornell University

09/07/17 / #20170253493

Dimensionally focused nanoparticle synthesis methodology

A methodology for synthesizing a nanoparticle batch, such as but not limited to a metal chalcogenide nanoparticle batch and further such as but not limited to a metal sulfide nanoparticle batch is predicated upon an expectation and observation that at elevated concentrations of at least one reactant material within a... Cornell University

09/07/17 / #20170253590

Small molecule ire1-alpha inhibitors

Described herein are IRE1α inhibitors, compositions containing such inhibitors, and methods of treatment that include administration of such compounds. Exemplary compounds are provided throughout the application.... Cornell University

09/07/17 / #20170255837

Retinal encoder for machine vision

A method is disclosed including: receiving raw image data corresponding to a series of raw images; processing the raw image data with an encoder to generate encoded data, where the encoder is characterized by an input/output transformation that substantially mimics the input/output transformation of one or more retinal cells of... Cornell University

08/31/17 / #20170247145

A device for delivering odors and methods of using the same

Disclosed herein are kits, devices and methods for promoting, supporting and enhancing olfactory function. The kits of the present disclosure relate to devices for stimulating olfactory function that include odorous pods selected from a group of odors or more than one group of odors, whereby each odorous pod is located... Cornell University

08/31/17 / #20170248584

Identifying status of male fertility by determining sperm capacitation

This disclosure provides a method for determining male fertility status. The method comprises determining GM1 distribution patterns following induced sperm capacitation, identifying the frequency of distribution of various patterns, and determining if the frequency distribution of certain GM1 patterns in response to induced capacitation is altered. Based on the change... Cornell University

08/31/17 / #20170248937

System and methods for three-dimensional printing

A fast and economical system and methods directed to low-fidelity fabrication of three-dimensional (3D) objects using 3D printing. The invention facilitates rapid prototyping by providing a wireframe structure in the form of the underlying design structure of a 3D model, which may be useful for a variety of reasons including... Cornell University

08/31/17 / #20170249426

A system and methods for managing healthcare resources

The present invention is directed to a system and a non-transitory computer readable medium for managing use of hospitalization healthcare resources. Specifically, the embodiments of the invention may accept information from one or more sources, select a population unit, define one or more population units according to enhanced comorbidity, assign... Cornell University

08/24/17 / #20170239378

Fluorescent silica-based nanoparticles

The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1... Cornell University

08/24/17 / #20170240593

Aromatic-cationic peptides and uses of same

The present disclosure provides aromatic-cationic peptide compositions and methods of using the same. The methods comprise use of the peptides in electron transport and electrical conductance.... Cornell University

08/24/17 / #20170240903

Modulation of breast cancer growth by modulation of xbp1 activity

Described herein is a previously unknown function of XBP1 in triple-negative breast cancer (TNBC). It is shown that XBP1 is preferentially spliced and activated in TNBC, and that deletion of XBP1 significantly blocks triple negative breast tumor growth. Strikingly, XBP1 is required for the self-renewal of breast tumor initiating cells... Cornell University

08/24/17 / #20170241765

Optical sensing based on measurements of displacements induced by optical forces in viscoelastic media using phase-sensitive optical coherence tomography

A system for providing optical actuation and optical sensing can include an optical coherence tomography (OCT) device that performs optical imaging of a sample based on optical interferometry from an optical sampling beam interacting with an optical sample and an optical reference beam; an OCT light source to provide an... Cornell University

Patent Packs
08/24/17 / #20170242337

Radiation-sensitive composition and pattern-forming method

A radiation-sensitive composition includes particles including a metal oxide as a principal component, and an organic solvent. A metal atom constituting the metal oxide includes a first metal atom that is a zinc atom, a boron atom, an aluminum atom, a gallium atom, a thallium atom, a germanium atom, an... Cornell University

08/10/17 / #20170224764

Therapeutic targeting of mitochondria to prevent osteoarthritis

The present technology provides methods of preventing or treating osteoarthritis (OA) and/or post-traumatic osteoarthritis (PTOA). In some embodiments, the methods provide administering aromatic-cationic peptides in effective amounts to treat or prevent cartilage degeneration and/or chondrocyte death such as that found in a subject suffering from, or predisposed to OA or... Cornell University

08/10/17 / #20170226283

Polyester stereocomplexes, compositions comprising same, and methods of making and using same

Compositions comprising stereocomplexes of enantiomeric polymer chains having individual repeat units formed from the reaction of an epoxide and cyclic anhydride. The compositions can be made by mixing two types of enantiomeric polymer chains having opposite absolute stereochemistry. The compositions can be used in applications such as biomedical applications and... Cornell University

08/03/17 / #20170216448

Inhibitors of fusion between viral and cell membranes as well as compositions and methods of using them

The present application relates to an inhibitor of fusion between a viral membrane from an enveloped virus and a cell membrane, where the viral membrane comprises a fusion mediating protein including a C-terminal peptide. The inhibitor comprises the C-terminal peptide of the fusion mediating protein from an enveloped virus and... Cornell University

07/27/17 / #20170210979

Targeting enhanced production through deep carbonate stimulation: stabilized acid emulions containing insoluble solid materials with desired wetting properties

A stabilized emulsified acid composition for deep carbonate formation stimulation is provided. The stabilized acid emulsion composition includes a petroleum operable to provide a barrier between an acid and a reservoir rock, the acid operable to react with the reservoir rock to dissolve the reservoir rock and produce a wormhole,... Cornell University

07/27/17 / #20170212103

Method for relative quantification of nucleic acid sequence, expression, or copy changes, using combined nuclease, ligation, and polymerase reactions

The present invention is directed to methods for identifying the presence of one or more target nucleotide sequences in a sample that involve a nuclease-ligation reaction. In some embodiments, the ligation products formed in the nuclease-ligation process of the present invention are subsequently amplified using a polymerase chain reaction. The... Cornell University

07/27/17 / #20170212679

Oblivious parallel random access machine system and methods

A secure parallel processing technique for converting any parallel random access machine (PRAM) into an oblivious parallel random access machine (OPRAM), whose distribution of memory accesses is statistically independent of the data (with negligible error), while only inducing a polylogarithmic slowdown to both the total and parallel complexities of the... Cornell University

07/27/17 / #20170214514

Methods and systems for synchronization between multiple clock domains

A synchronization solution is described, which, in one aspect, allowed finer grained segmentation of clock domains on a chip. This solution incorporates computation into the synchronization overhead time and is called Gradual Synchronization. With Gradual Synchronization as a synchronization method, the design space of a chip could easily mix both... Cornell University

07/20/17 / #20170202887

Probiotic compositions and methods

The present invention relates to probiotic compositions and methods of using such compositions. In particular, the present invention provides method of using Faecalibacterium spp. to improve weight gain, provide prophylaxis against diarrhea and/or improve feed efficiency in an animal.... Cornell University

07/20/17 / #20170202894

Omega-3 fatty acid enrichment of poultry products with defatted microalgae animal feed

The present invention relates to omega-3 fatty acid enrichment, and n-6 to n-3 fatty acid ratio improvement, of poultry products using animal feed supplemented with defatted microalgae, and treatment methods involving such poultry products. One aspect of the present invention relates to a method of producing poultry eggs with elevated... Cornell University

07/20/17 / #20170204459

Method for identification and enumeration of nucleic acid sequence, expression, copy, or dna methylation changes, using combined nuclease, ligase, polymerase, and sequencing reactions

The present invention relates to a method for the highly specific, targeted capture of regions of human genomes and transcriptomes from the blood, i.e. from cell free circulating DNA, exosomes, microRNA, circulating tumor cells, or total blood cells, to allow for the highly sensitive detection of mutation, expression, copy number,... Cornell University

07/13/17 / #20170200543

Compact undulator system and methods

An undulator with a compact construction is provided that reduces weight, complexity and cost. The compact undulator system and methods provides mechanical integrity without compromising magnetic field quality.... Cornell University

07/06/17 / #20170191077

Compositions and methods for deterring feeding by psyllids

The invention relates to a plant that includes a transgene encoding a heterologous polypeptide conferring on plant expressing said polypeptide resistance to a hemipteroid sap-sucking insect. The transgene is also expressed in a plant component (such as a leaf). Typically, expression of such polypeptides deters feeding by insects such as... Cornell University

07/06/17 / #20170191113

Detection of dna methylation using combined nuclease ligation reactions

The present invention is directed to methods for identifying the presence of one or more methylated or unmethylated target nucleotide sequences in a sample that involve coupled methylation sensitive restriction enzyme digestion-ligation and/or extension processes. In some embodiments, the ligation and primary extension products formed in the reaction processes of... Cornell University

07/06/17 / #20170191193

Process for preparing a silicon-carbon nanocomposite nanofiber

Provided herein are nanofibers comprising carbon precursors, nanofibers comprising carbon matrices, and processes for preparing the same. In specific examples, provided herein are high performance lithium ion battery anodic nanofibers comprising non-aggregated silicon domains in a continuous carbon matrix.... Cornell University

Patent Packs
06/29/17 / #20170182358

System and training tongue as a treatment for obstructive sleep apnea

The present disclosure describes systems and methods for the treatment of obstructive sleep apnea. The system includes a mouthpiece. The mouthpiece includes a force plate that a user can press against with their tongue. Pressing the force plate enables the user to strengthen their tongue. The system also includes a... Cornell University

06/29/17 / #20170183664

Small rnas (srna) that activate transcription

Disclosed herein are compositions for transcriptional regulation of a target gene, and methods of using the compositions. The compositions utilize a novel antisense RNA design that activates transcription of a target gene and involve a sense genetic construct that represses transcription of the target gene, and an antisense construct selected... Cornell University

06/29/17 / #20170183718

Methods and reagents for riboswitch analysis

We provide isolated TPP and preQ1 class II riboswitches which are labelled for FRET studies of ribosome function. The riboswitches may be used in assays to determine riboswitch function, and to test the activity of compounds in modulating riboswitch function.... Cornell University

06/29/17 / #20170187059

Symmetric redox flow battery containing organic redox active molecule

A redox flow battery comprising: a positive compartment containing a positive electrode in contact with a liquid electrolyte comprised of an organic redox active molecule dissolved in a solvent; a negative compartment containing a negative electrode in contact with a liquid electrolyte comprised of said organic redox active molecule dissolved... Cornell University

06/22/17 / #20170172174

Process and rapid freezing of consumable and non-consumable products using the expansion of dense gas

The present disclosure provides, inter alia, processes and apparatuses for rapid freezing of consumable and non-consumable products. In certain embodiments, the processes and apparatuses of the present disclosure yield the rapidly frozen consumable and non-consumable products using the expansion of dense gas. The present disclosure also provides consumable and non-consumable... Cornell University

06/22/17 / #20170172227

Temperature-regulating garment

A fabric for temperature regulation and a wearable device for regulating a temperature of a wearer are disclosed. The wearable device has a fabric and one or more microtubes woven in the fabric. Each microtube has an inlet and an outlet, and each microtube is configured to transport a gas... Cornell University

06/22/17 / #20170173560

Porous cyclodextrin polymeric materials and methods of making and using same

A nucleophilic substitution reaction to crosslink cyclodextrin (CD) polymer with rigid aromatic groups, providing a high surface area, mesoporous CD-containing polymers (P-CDPs). The P-CDPs can be used for removing organic contaminants from water. By encapsulating pollutants to form well-defined host-guest complexes with complementary selectivities to activated carbon (AC) sorbents. The... Cornell University

06/22/17 / #20170175101

Mesoporous catalysts of magnetic nanoparticles and free-radicalproducing enzymes, and methods of use

A composition comprising mesoporous aggregates of magnetic nanoparticles and free-radical producing enzyme (i.e., enzyme-bound mesoporous aggregates), wherein the mesoporous aggregates of magnetic nanoparticles have mesopores in which the free-radical-producing enzyme is embedded. Methods for synthesizing the enzyme-bound mesoporous aggregates are also described. Processes that use said enzyme-bound mesoporous aggregates for... Cornell University

06/22/17 / #20170175200

Use of double-stranded dna in exosomes: a novel biomarker in cancer detection

The present invention is directed to methods of prognosing, treating, or managing treatment of cancer in a subject. These methods involve selecting a subject having cancer, obtaining, from the selected subject, a sample containing exosomes, recovering the exosomes from the sample, and isolating the double-stranded DNA from within the exosomes.... Cornell University

06/22/17 / #20170175297

Reinforcing nanofiber additives

Provided herein are high performance reinforcing nanostructure additives, high throughput processes for using such additives, and composites comprising such additives. Such nanostructure additives include nanofibers, including nanofiber fragments, of various matrix materials, including metal(s) (e.g., elemental metal(s), metal alloy(s), etc.), metal oxide(s), ceramic(s), metal carbide(s), carbon (e.g., carbon nanocomposites comprising... Cornell University

06/22/17 / #20170178705

Circuits and devices based on enhanced spin hall effect for efficient spin transfer torque

Devices or circuits based on spin torque transfer (STT) and Spin Hall effect are disclosed by using a spin Hall effect (SHE) metal layer coupled to a magnetic free layer for various applications. The efficiency or strength of the STT effect based on this combination of SHE and STT can... Cornell University

06/22/17 / #20170179532

Dendrite inhibiting electrolytes for metal-based batteries

A metal-based battery includes at least one metal electrode immersed within an electrolyte that includes: (1) an aprotic solvent; (2) a simple halogen containing material; and (3) optionally a metal salt that includes a complex halogen containing anion. The simple halogen containing material may include a metal halide salt that... Cornell University

06/22/17 / #20170179558

Solar flow battery

A solar flow battery comprising: a positive compartment containing at least one positive electrode in contact with a positive electrolyte containing a first redox active molecule; a negative compartment containing at least one negative electrode in contact with a negative electrolyte containing a second redox active molecule, wherein said first... Cornell University

06/15/17 / #20170164935

Urethral catheterless radical prostatectomy

A method and device for facilitating the anastomotic healing of a patient after a radical prostatectomy surgical procedure, without a urethral catheter, comprising the steps of performing a radical prostatectomy, fixedly positioning a splinting element between the urethra and the bladder, across the urethral opening, placing the splinting element during... Cornell University

06/15/17 / #20170166980

Thyroid tumors identified

The invention relates to methods and kits for detecting thyroid cancer by detecting differences in the expression of genes that are differentially expressed in thyroid cancer cells.... Cornell University

06/15/17 / #20170169899

Piezoelectric and logic integrated delay line memory

Delay line memory device, systems and methods are disclosed. In one aspect, a delay line memory device includes a substrate; an electronic unit disposed on the substrate and operable to receive, amplify, and/or synchronize data signals into a bit stream to be transmitted as acoustic pulses carrying data stored in... Cornell University

06/15/17 / #20170170785

Scalable terahertz phased array and method

A device and method for terahertz signal generation are disclosed. Oscillators are arranged in a two-dimensional array, each oscillator connected to a corresponding antenna. Each oscillator is unidirectional connected to its adjacent oscillators by a phase shifter. A method for generating a steerable terahertz signal utilizes an array of oscillators... Cornell University

06/08/17 / #20170158692

Compounds and methods for inhibiting fascin

Provided are compounds, compositions and methods for inhibiting fascin activity or treating a condition or disorder mediated by fascin activity in a subject in need thereof.... Cornell University

06/01/17 / #20170151584

Porous resin structures

A method providing direct access to porous three-dimensionally (3D) continuous polymer network structures and shapes by combining BCP-resol co-assembly with CO2 laser-induced transient heating. The CO2 laser source transiently heats the BCP-directed resol hybrid films to high temperatures at the beam position, inducing locally controlled resol thermopolymerization and BCP decomposition... Cornell University

05/25/17 / #20170143784

Mitochondrial-targeted antioxidants protect against mechanical ventilation-induced diaphragm dysfunction and skeletal muscle atrophy

The present disclosure provides methods and compositions for preventing or treating MV-induced or disuse-induced skeletal muscle infirmities in a mammalian subject. The methods further include administering to the subject an effective amount of an aromatic-cationic peptide.... Cornell University

05/18/17 / #20170135964

Methods of treating diseases associated with high-fat diet and vitamin a deficiency using retinoic acid receptor agonists

This invention relates to pharmaceutical composition and methods of using vitamin A and/or RARβ agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency.... Cornell University

05/18/17 / #20170136255

Method and providing transcranial magnetic stimulation (tms) to a patient

wherein the number of magnet assemblies mounted on the head mount, their individual positioning on the head mount, and their selective provision of a rapidly changing magnetic field is selected so as to allow the spatial, strength and temporal characteristics of the magnetic field to be custom tailored for each... Cornell University

05/18/17 / #20170138933

Smfret with membrane proteins

This disclosure is directed to methods of conducting dynamic single-molecule fluorescence studies such as smFRET on a membrane protein which permits observation and quantification of conformational dynamics of a membrane protein. Also disclosed herein are mutant membrane proteins in which one or more mutations have been introduced for affixing a... Cornell University








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