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Flodesign Sonics Inc patents


Recent patent applications related to Flodesign Sonics Inc. Flodesign Sonics Inc is listed as an Agent/Assignee. Note: Flodesign Sonics Inc may have other listings under different names/spellings. We're not affiliated with Flodesign Sonics Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "F" | Flodesign Sonics Inc-related inventors


Acoustophoretic separation technology using multi-dimensional standing waves

A system having improved trapping force for acoustophoresis is described where the trapping force is improved by manipulation of the frequency of the ultrasonic transducer. The transducer includes a ceramic crystal. The crystal may be directly exposed to fluid flow. The crystal may be air backed, resulting in a higher... Flodesign Sonics Inc

Acoustic perfusion devices

Methods are disclosed for separating beads and cells from a host fluid. The method includes flowing a mixture containing the host fluid, the beads, and the cells through an acoustophoretic device having an ultrasonic transducer including a piezoelectric material driven by a drive signal to create a multi-dimensional acoustic standing... Flodesign Sonics Inc

Large scale acoustic separation device

Devices for separating a host fluid from a second fluid or particulate are disclosed. The devices include an acoustic chamber, a fluid outlet at a top end of the acoustic chamber, a concentrate outlet at a bottom end of the acoustic chamber, and an inlet on a first side end... Flodesign Sonics Inc

System for generating high concentration factors for low cell density suspensions

Acoustophoretic devices and methods for concentrating targeted biological cells in a reduced volume using multi-dimensional acoustic standing waves are disclosed. The methods include flowing a mixture of a host fluid and the biological cells through an acoustophoretic device. The acoustophoretic devices include an inlet, an outlet, and a flow chamber... Flodesign Sonics Inc

Acoustic perfusion devices

Acoustic perfusion devices for separating biological cells from other material in a fluid mixture are disclosed. The devices include an inlet port, an outlet port, and a collection port that are connected to an acoustic chamber. An ultrasonic transducer creates an acoustic standing wave in the acoustic chamber that permits... Flodesign Sonics Inc

Acoustically-enhanced separators for aircraft engines

Engine inlets are disclosed that include an intake opening for the ingress of incoming air and acoustic filtration means for generating an acoustic wave that separates or clarifies material from the incoming air. The acoustic filtration means can include at least one ultrasonic transducer with a piezoelectric material configured to... Flodesign Sonics Inc

Acoustophoresis device with dual acoustophoretic chamber

An acoustophoresis device includes an acoustic chamber with a piezoelectric element located within its volume. The piezoelectric element vibrates and generates acoustic standing waves from both sides, so that particles can be separated from fluid passing through the acoustic chamber. This permits the element to be cooled more efficiently, reducing... Flodesign Sonics Inc

Acoustophoretic enhanced system for use in bioreactors

A system for enhancing the separation of particles or fluids from water is disclosed. A tank or bioreactor is provided with an open submersible acoustophoretic separator. The separator captures and holds fluid droplets or particles such as cells, permitting them to coalesce or agglomerate until they are large enough and... Flodesign Sonics Inc

Therapeutic cell washing, concentration, and separation utilizing acoustophoresis

Multi-stage acoustophoretic devices for continuously separating a second fluid or a particulate from a host fluid are disclosed. Methods of operating the multi-stage acoustophoretic devices are also disclosed. The systems may include multiple acoustophoretic devices fluidly connected to one another in series, each acoustophoretic device comprising a flow chamber, an... Flodesign Sonics Inc

Piezoelectric transducer for generation of an acoustic standing wave

Transducer assemblies that can be used in acoustophoretic systems are disclosed. The acoustophoretic systems including the transducer assemblies and methods of operating the acoustophoretic systems are also disclosed. The transducer assemblies include a housing, a polymeric film attached to the housing, and a piezoelectric material attached to the polymeric film.... Flodesign Sonics Inc

Acoustic bioreactor processes

A series of multi-dimensional acoustic standing waves is set up inside a growth volume of a bioreactor. The acoustic standing waves are used to hold a cell culture in place as a nutrient fluid stream flows through the cell culture. The nutrient fluid stream dislodges some cells from the cell... Flodesign Sonics Inc

Electronic configuration and control for acoustic standing wave generation

Aspects of the disclosure are directed to an apparatus for separating a second fluid or a particulate from a host fluid. That apparatus comprises a flow chamber with at least one inlet and at least one outlet. A drive circuit configured to provide a drive signal to a filter circuit... Flodesign Sonics Inc

Separation of multi-component fluid through ultrasonic acoustophoresis

An acoustic standing wave is utilized to separate components from a multi-component fluid, such as oil from an oil-water mixture, in a fluid flow scheme with an acoustophoresis device. For example, the flow scheme and device allows for trapping of the oil as the oil coalesces, agglomerates, and becomes more... Flodesign Sonics Inc

Acoustophoretic clarification of particle-laden non-flowing fluids

Acoustophoretic devices for separating particles from a non-flowing host fluid are disclosed. The devices include a substantially acoustically transparent container and a separation unit, with the container being placed within the separation unit. An ultrasonic transducer in the separation unit creates a planar or multi-dimensional acoustic standing wave within the... Flodesign Sonics Inc

Acoustophoretic device for angled wave particle deflection

Devices for separating materials from a host fluid are disclosed. The devices include a flow chamber, an ultrasonic transducer, and a reflector. The ultrasonic transducer and reflector create an angled acoustic standing wave oriented at an angle relative to the direction of mean flow through the flow chamber. The angled... Flodesign Sonics Inc

Acoustic separation of cellular supporting materials from cultured cells

Methods, systems, and apparatus for acoustic separation of cellular supporting materials such as microcarriers or microbubbles from cell culture are provided. In one aspect, a method includes flowing a fluid containing the cellular supporting material and the cells through a flow chamber; driving at least one acoustic transducer to launch... Flodesign Sonics Inc

Transducer and reflector configurations for an acoustophoretic device

Separation of particles or droplets from a host fluid may be achieved using a transducer and/or reflector that is a thin, non-planar structure. The thin non-planar structure improves operation of an acoustic standing wave generated by an acoustic transducer. The structure may operate as a pressure release boundary and may... Flodesign Sonics Inc

Acoustic separation of t cells

Acoustophoretic devices and methods for separating biological cells (particularly T-cells) from other fluids/materials using multi-dimensional acoustic standing waves are disclosed. The devices include an inlet, at least two outlets, and a flow chamber having an ultrasonic transducer-reflector pair. Specifically, T cells, B cells, or NK cells can be separated from... Flodesign Sonics Inc

Ultrasonic induced artificial black holes in phononic crystals

Acoustophoretic devices and methods for using such devices in various applications are disclosed. The devices include a flow chamber having an inlet; a phononic crystal within an active volume of the flow chamber; and ultrasonic transducer(s) that create an acoustic standing wave in the active volume. This combination results in... Flodesign Sonics Inc

Bioreactor using acoustic standing waves

A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor.... Flodesign Sonics Inc

Bioreactor using acoustic standing waves

A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor.... Flodesign Sonics Inc

Bioreactor using acoustic standing waves

A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor.... Flodesign Sonics Inc

Methods and particle aggregation using acoustic standing waves

Methods for generating particulate clusters and nodal trapping lines having desired widths are disclosed. The devices include an acoustic chamber having an inlet and an outlet. An ultrasonic transducer and reflector create a multi-dimensional acoustic standing wave that generates particulate clusters separated by a channel of fluid running therebetween and... Flodesign Sonics Inc

Bioreactor using acoustic standing waves

A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor.... Flodesign Sonics Inc

Bioreactor using acoustic standing waves

A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor.... Flodesign Sonics Inc

Acoustic perfusion devices

Methods are disclosed for separating beads and cells from a host fluid. The method includes flowing a mixture containing the host fluid, the beads, and the cells through an acoustophoretic device having an ultrasonic transducer including a piezoelectric material driven by a drive signal to create a multi-dimensional acoustic standing... Flodesign Sonics Inc

Ultrasound and acoustophoresis for collection and processing of oleaginous microorganisms

Microorganisms such as micro algae are collected and separated from a host medium such as water. Cellular walls and membranes of the microorganisms are then ruptured to release their lipids using a lipid extraction unit. Thereafter, the lipids from the host medium are collected and separated using a lipid collection... Flodesign Sonics Inc

System for generating high concentration factors for low cell density suspensions

Acoustophoretic devices and methods for concentrating targeted biological cells in a reduced volume using multi-dimensional acoustic standing waves are disclosed. The methods include flowing a mixture of a host fluid and the biological cells through an acoustophoretic device. The acoustophoretic devices include an inlet, an outlet, and a flow chamber... Flodesign Sonics Inc

Acoustic manipulation of particles in standing wave fields

A method for separating a second fluid or a particulate from a host fluid is disclosed. The method includes flowing the mixture through an acoustophoretic device comprising an acoustic chamber, an ultrasonic transducer, and a reflector. The transducer includes a piezoelectric material driven by a voltage signal to create a... Flodesign Sonics Inc

Multi-stage acoustophoresis device

An acoustophoresis device made up of modular components is disclosed. Several modules are disclosed herein, including ultrasonic transducer modules, input/output modules, collection well modules, and various connector modules. These permit different systems to be constructed that have appropriate fluid dynamics for separation of particles, such as biological cells, from a... Flodesign Sonics Inc

Acoustophoresis device with modular components

An acoustophoresis device made up of modular components is disclosed. Several modules are disclosed herein, including ultrasonic transducer modules, input/output modules, collection well modules, and various connector modules. These permit different systems to be constructed that have appropriate fluid dynamics for separation of particles, such as biological cells, from a... Flodesign Sonics Inc

Acoustophoretic device with piezoelectric transducer array

An apparatus for separating particles from a fluid stream includes a flow chamber that has at least one inlet and at least one outlet. At least one ultrasonic transducer is located on a wall of the flow chamber. The transducer includes a piezoelectric array with at least two piezoelectric elements.... Flodesign Sonics Inc

Acoustic blood separation processes and devices

Acoustophoretic devices are disclosed. The devices include a flow chamber, an ultrasonic transducer, a reflector, an inlet, a filtrate outlet, a concentrate outlet, and optionally a lipid collection trap. The ultrasonic transducer and reflector create a multi-dimensional acoustic standing wave in the flow chamber that traps and separates red blood... Flodesign Sonics Inc

Acoustophoretic separation technology using multi-dimensional standing waves

A system having improved trapping force for acoustophoresis is described where the trapping force is improved by manipulation of the frequency of the ultrasonic transducer. The transducer includes a ceramic crystal. The crystal may be directly exposed to fluid flow. The crystal may be air backed, resulting in a higher... Flodesign Sonics Inc

02/02/17 / #20170029802

Acoustic affinity separation

Methods and systems for separating a first biomaterial from a second biomaterial can use functionalized material retained in a liquid-filled chamber at locales within an acoustic standing wave field. A culture suspension containing the first biomaterial and the second biomaterial flows into the liquid-filled chamber and at least portions of... Flodesign Sonics Inc

01/12/17 / #20170008029

Non-planar and non-symmetrical piezoelectric crystals and reflectors

An acoustophoretic device is disclosed. The acoustophoretic device includes an acoustic chamber, an ultrasonic transducer, and a reflector. The ultrasonic transducer includes a piezoelectric material driven by a voltage signal to create a multi-dimensional acoustic standing wave in the acoustic chamber emanating from a non-planar face of the piezoelectric material.... Flodesign Sonics Inc








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