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Ge Healthcare Bioprocess R & d Ab patents


Recent patent applications related to Ge Healthcare Bioprocess R & d Ab. Ge Healthcare Bioprocess R & d Ab is listed as an Agent/Assignee. Note: Ge Healthcare Bioprocess R & d Ab may have other listings under different names/spellings. We're not affiliated with Ge Healthcare Bioprocess R & d Ab, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "G" | Ge Healthcare Bioprocess R & d Ab-related inventors


Parallel assembly of chromatography column modules

A parallel assembly (2; 11; 51) of chromatography column modules (3a,b,c; 13a,b,c; 53a,b,c, 90a, b), the assembly having one common assembly inlet (15; 55) and one common assembly outlet (17; 57), each column module comprising a bed space (29) filled with chromatography medium and each column module comprises integrated fluid... Ge Healthcare Bioprocess R & d Ab

Separation method

e) cleaning the separation matrix with a cleaning liquid comprising at least 0.5 M NaOH.... Ge Healthcare Bioprocess R & d Ab

Sanitization affinity chromatography matrices

The invention discloses a method for cleaning or sanitization of an affinity chromatography matrix, comprising the steps of: a) providing an affinity chromatography matrix having oxidation-tolerant proteinaceous ligands coupled to a support, b) contacting the matrix with a sanitization solution comprising at least one oxidant defined by formula I, R—O—O—H... Ge Healthcare Bioprocess R & d Ab

Mutated immunoglobulin-binding polypeptides

An Fc-binding polypeptide of improved alkali stability, comprising a mutant of an Fc-binding domain of Staphylococcus Protein A (SpA), as defined by SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO:3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:22,... Ge Healthcare Bioprocess R & d Ab

Separation matrix

b) the porous support comprises cross-linked polymer particles having a volume-weighted median diameter (d50,v) of 56-70 micrometers and a dry solids weight of 55-80 mg/ml.... Ge Healthcare Bioprocess R & d Ab

Modified kappa light chain-binding polypeptides

A kappa light chain-binding polypeptide comprising or consisting essentially of one or more binding domains of Peptostreptococcus Protein L, each of said domains being selected from the group consisting of domain 2, domain 3 and domain 4.... Ge Healthcare Bioprocess R & d Ab

Modified kappa light chain-binding polypeptides

The invention discloses kappa light chain-binding polypeptide comprising a mutated binding domain of Peptostreptococcus protein L, wherein at least one asparagine residue of a parental domain defined by, or having at least 95% or 98% sequence homology with, SEQ ID NO: 2-6 or 2 has been mutated to another amino... Ge Healthcare Bioprocess R & d Ab

Chromatography ligand comprising domain c from staphylococcus aureus protein a for antibody isolation

The present invention relates to a chromatography ligand, which comprises Domain C from Staphylococcus protein A (SpA), or a functional fragment or variant thereof. The chromatography ligand presents an advantageous capability of withstanding harsh cleaning in place (CIF) conditions, and is capable of binding Fab fragments of antibodies. The ligand... Ge Healthcare Bioprocess R & d Ab

Affinity chromatography matrix

The invention discloses a polypeptide capable of binding immunoglobulins or immunoglobulin-containing proteins, which polypeptide comprises six or more domains of protein Z or the C domain of protein A or a functional variant thereof. It also discloses separation matrices comprising the polypeptide and methods of using the separation matrices for... Ge Healthcare Bioprocess R & d Ab

Stackable chromatography column modules and flow control blocks

The invention discloses a flow control block for a stack of chromatography column modules, as well as a stack of chromatography modules comprising at least one flow control block. The flow control block is in a first position or configuration capable of connecting two chromatography column modules, or a chromatography... Ge Healthcare Bioprocess R & d Ab

Packing chromatography columns

introducing the pre-sterilized chromatography medium into the pre-sterilized chromatography column using aseptic equipment, thereby providing an aseptic chromatography column comprising chromatography medium.... Ge Healthcare Bioprocess R & d Ab

Separation method and separation matrix

The invention discloses a method of separating a biomolecule from at least one other component in a liquid, comprising a step of contacting said liquid with a separation matrix comprising a solid support and polymer chains bound to said solid support. The polymer chains comprise units derived from a first... Ge Healthcare Bioprocess R & d Ab

Chromatography columns, systems and methods

The present invention relates to axial flow chromatography columns, methods for separating one or more analytes in a liquid by the use of such columns, and systems employing such columns. The column comprises a first port and a second port, the first port and said second port being at essentially... Ge Healthcare Bioprocess R & d Ab

Mutated immunoglobulin-binding protein

The present invention relates to an immunoglobulin-binding protein, wherein at least one asparagine residue has been mutated to an amino acid other than glutamine or aspartic acid, which mutation confers an increased chemical stability at pH-values of up to about 13-14 compared to the parental molecule. The protein can for... Ge Healthcare Bioprocess R & d Ab

Method for endotoxin removal

The present invention relates to a method for endotoxin removal from a sample comprising the following steps: combining the sample comprising one or more target molecule(s) with a chromatography media comprising beads having an inner porous core functionalized with ligands capable of binding endotoxin and an outer porous layer without... Ge Healthcare Bioprocess R & d Ab

Micro titre plate

A micro titre plate comprising a number of wells filled with separation matrix. According to the invention the volume of the separation matrix is varied between at least some of the wells.... Ge Healthcare Bioprocess R & d Ab

Chromatography medium

The present invention is within the field of chromatography. More precisely, it relates to a novel chromatography medium, namely a hydrophobic medium provided with different lids excluding molecules over a certain size due to the porosity of the hydrophobic medium and/or the porosity of the lid. The invention also relates... Ge Healthcare Bioprocess R & d Ab

Chromatography method

The present invention relates to a method for removal of large contaminants, such as virus, in a chromatographic process for purification of a target molecule, preferably monoclonal antibodies, mAbs, by using a specifically designed chromatographic bead having a thin outer layer and a core functionalized with a ligand adsorbing the... Ge Healthcare Bioprocess R & d Ab








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