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Gilead Pharmasset Llc patents


Recent patent applications related to Gilead Pharmasset Llc. Gilead Pharmasset Llc is listed as an Agent/Assignee. Note: Gilead Pharmasset Llc may have other listings under different names/spellings. We're not affiliated with Gilead Pharmasset Llc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "G" | Gilead Pharmasset Llc-related inventors


Nucleoside phosphoramidate prodrugs

Also disclosed are methods of treatment, uses, and processes for preparing each of which utilize the compound represented by formula I.... Gilead Pharmasset Llc

Combination formulation of three antiviral compounds

Disclosed are pharmaceutical compositions comprising three antiviral compounds. In particular, the pharmaceutical compositions comprise an effective amount of velpatasvir, an effective amount of sofosbuvir, and an effective amount of voxilaprevir. Also disclosed are methods of use for the pharmaceutical composition.... Gilead Pharmasset Llc

Compositions and methods for treating hepatitis c virus

Disclosed herein are a composition and unit dosage form for the treatment of hepatitis C virus (HCV) infection comprising GS-7977 and at least one pharmaceutically acceptable excipient, as well as methods for making said composition and unit dosage form. Also disclosed herein is a method of treating a subject, preferably... Gilead Pharmasset Llc

Methods of treating hepatitis e viral infection

Disclosed herein are methods of treating a hepatitis E viral infection comprising administering to a human subject in need thereof a therapeutically effective amount of the compound sofosbuvir, also known as (S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino) propanoate. Some methods further comprise concomitantly administering ribavirin to the subject. In some methods, the treatment is... Gilead Pharmasset Llc

Solid forms of an antiviral compound

Also provided are processes of manufacture and methods of using the amorphous and crystalline forms.... Gilead Pharmasset Llc

Preparation of 2'-fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives

The present invention provides (i) processes for preparing a 2′-deoxy-2′-fluoro-2′-methyl-D-ribonolactone derivatives, (ii) conversion of intermediate lactones to nucleosides with potent anti-HCV activity, and their analogues, and (iii) methods to prepare the anti-HCV nucleosides containing the 2′-deoxy-2′-fluoro-2′-C-methyl-β-D-ribofuranosyl nucleosides from a preformed, preferably naturally-occurring, nucleoside.... Gilead Pharmasset Llc

Solid forms of an antiviral compound

Also provided are processes of manufacture and methods of using these crystalline forms.... Gilead Pharmasset Llc

Combination formulation of two antiviral compounds

Disclosed are pharmaceutical compositions having an effective amount of substantially amorphous ledipasvir and an effective amount of substantially crystalline sofosbuvir.... Gilead Pharmasset Llc

Methods for treating hcv

This invention relates to combinations of therapeutic molecules useful for treating hepatitis C virus infection. The present invention relates to methods, uses, dosing regimens, and compositions.... Gilead Pharmasset Llc

Process for the preparation of a fluorolaction derivative

The acylated fluor lactones of formula V, particularly the benzoyl derivative with R1=benzyl are important precursors for the synthesis of prodrug compounds which have the potential to be potent inhibitors of the Hepatitis C Virus (HCV) NS5B polymerase.... Gilead Pharmasset Llc

Antiviral compounds

The disclosure is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.... Gilead Pharmasset Llc

Combination formulation of two antiviral compounds

and an effective amount of sofosbuvir wherein the sofosbuvir is substantially crystalline. Also disclosed are methods of use for the pharmaceutical composition.... Gilead Pharmasset Llc

Antiviral compounds

The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.... Gilead Pharmasset Llc








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