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Hoffmann la Roche Inc
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Hoffmann la Roche Inc patents

Recent patent applications related to Hoffmann la Roche Inc. Hoffmann la Roche Inc is listed as an Agent/Assignee. Note: Hoffmann la Roche Inc may have other listings under different names/spellings. We're not affiliated with Hoffmann la Roche Inc, we're just tracking patents.

ARCHIVE: New 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "H" | Hoffmann la Roche Inc-related inventors




Date Hoffmann la Roche Inc patents (updated weekly) - BOOKMARK this page
03/23/17 new patent  Antiviral compounds
03/23/17 new patent  Peptides as oxytocin agonists
03/23/17 new patent  Peptides as oxytocin agonists
03/23/17 new patent  Method for the selection of a long-term producing cell using histone acylation as markers
03/09/175-oxa-2-azabicyclo[2.2.2]octan-4-yl and 5-oxa-2-azabicyclo[2.2.1]heptan-4-yl derivatives
03/09/17Isoform enriched antibody preparation and obtaining it
03/09/17Responsiveness to angiogenesis inhibitors
03/09/17Method for production of polypeptides
03/02/17Process for making lysine-glutamic acid dipeptide derivatives
03/02/17Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis b virus infection
03/02/17Indolin-2-one and 1,3-dihydro-pyrrolo[3,2-c]pyridin-2-one derivatives
03/02/17Covalently linked helicar-anti-helicar antibody conjugates and uses thereof
03/02/17Covalently linked polypeptide toxin-antibody conjugates
03/02/17Modulation of cell growth and glycosylation in recombinant glycoprotein production
02/23/17New bicyclic derivatives
02/23/17Combination therapy of antibodies against human csf-1r and antibodies against human pd-l1
02/23/17Monovalent blood brain barrier shuttle modules
02/23/17Modified pseudomonas exotoxin a
02/16/17Glyt1 inhibitors for use in the treatment of hematological disorders
02/16/17Morpholin-pyridine derivatives
02/16/17Fc-region variants with improved protein a-binding
02/09/17Use of n-(4-tert-butylbenzyl)-3-chloro-n-[2-(4-chloro-3-ethyl-phenyl)-ethyl]-2-fluoro-5-trifluoromethyl-benzamide for the treatment of eye diseases
02/09/17Mglu2/3 antagonists for the treatment of intellectual disabilities
02/09/17Novel pyrazol derivatives
02/09/17Solid forms of a pharmaceutically active compound
02/09/17Fc-region variants with modified fcrn-binding properties
02/09/17Fc-region variants with modified fcrn- and maintained protein a-binding properties
02/09/17G-alpha interacting vesicle associated protein (giv) as a predictive marker in stage ii colorectal cancer
02/02/17Selective inhibitors of undifferentiated cells
02/02/17New diazaspirocycloalkane and azaspirocycloalkane
02/02/17Antibodies against human angiopoietin 2
02/02/17Antibodies against human csf-1r and uses thereof
02/02/17Bispecific her2 antibodies and methods of use
01/26/17Small molecule conjugates for intracellular delivery of biologically active compounds
01/19/17Benzazepine dicarboxamide compounds
01/19/17Use of pegylated igf-1 variants for the treatment of neuromuscular disorders
01/19/17Optimized antibody capturing by mixed mode chromatography
01/19/17Antibodies against human csf-1r and uses thereof
01/12/17Ethynyl derivatives
01/12/17Bicyclic compounds as autotaxin (atx) and lysophosphatidic acid (lpa) production inhibitors
01/12/17Spiro-oxazolones
01/12/17Condensed [1,4] diazepine compounds as autotaxin (atx) and lysophosphatidic acid (lpa) production inhibitors
01/12/17Method for purifying pegylated erythropoietin
01/12/17Use of the binding domain of a subunit of a multi-subunit structure for targeted delivery of pharmaceutically active entities to the multi-subunit structure
01/05/17Pharmaceutical composition with improved bioavailability
01/05/17Compounds for the treatment of cancer
01/05/17Spr-based bridging assay format for determining the biological activity of multivalent, multispecific molecules
12/29/16Novel pyridine derivatives
12/29/16Novel pyridine derivatives
12/29/16Separation of bispecific antibodies and bispecific antibody production side products using hydroxyapatite chromatography
12/29/16Humanized anti-tau(ps422) antibodies and methods of use
12/22/16Small molecule based conversion of somatic cells into neural crest cells
12/22/16Conversion of somatic cells to induced reprogrammed neural stem cells (irnscs)
12/15/16Ethynyl derivatives
12/15/16Removal of target cells by circulating virus-specific cytotoxic t-cells using mhc class i comprising complexes
12/08/16Spiro-oxazolones
12/01/16Combination therapy of an anti-cd20 antibody with a bcl-2 inhibitor and a mdm2 inhibitor
11/24/16Antigen binding molecules comprising a trimeric tnf family ligand
11/17/16(hetero)aryl imidazoles/pyrazoles for treatment of neurological disorders
11/17/16Novel process for the recovery of beta acetylfuranoside
11/17/16Use of peptidylglycine alpha-amidating monooxigenase (pam) for c-terminal amidation
11/17/16Identification of patients in need of pd-l1 inhibitor cotherapy
11/10/16Biospecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles
11/10/16Flouro-naphthyl derivatives
11/10/16Novel imidazoles for the treatment and prophylaxis of respiratory syncytial virus infection
Patent Packs
11/10/16N-phenyl-lactam derivatives capable of stimulating neurogenesis and their use in the treatment of neurological disorders
11/10/16Process for the preparation of n-[(3-aminooxetan-3-yl)methyl]-2-(1,1-dioxo-3,5-dihydro-1,4-benzothiazepin-4-yl)-6-methyl-quinazolin-4-amine
11/10/16Novel tetrahydropyridopyrimidines and tetrahydropyridopyridines for the treatment and prophylaxis of hepatitis b virus infection
11/10/16Novel sulfonimidoylpurinone compounds and derivatives for the treatment and prophylaxis of virus infection
11/10/16Novel 3-substituted 5-amino-6h-thiazolo[4,5-d]pyrimidine-2, 7-dione compounds for the treatment and prophylaxis of virus infection
11/10/16Tnfa-il-17 bispecific antibodies
11/10/16Improved recombinant polypeptide production methods
11/03/16Inhibitors of bruton's tyrosine kinase
11/03/165-aryl-1-imino-1-oxo-[1,2,4]thiadiazines
11/03/16Multispecific domain exchanged common variable light chain antibodies
11/03/16Method for the recombinant production of a polypeptide in prokaryotic cells
11/03/16Biomarkers and methods for progression prediction for chronic kidney disease
10/27/16Lipidated incretin receptor ligand human immunoglobulin fc-region fusion polypeptides
10/27/16Inhibitors of bruton's tyrosine kinase
10/27/16Interference-suppressed immunoassay to detect anti-drug antibodies in serum samples
Patent Packs
10/20/16Novel combination treatment for acute myeloid leukemia (aml)
10/20/16Inhibitors of bruton's tyrosine kinase
10/20/16Mutant transaminases as well as methods and uses relating thereto
10/13/16Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis b virus infection
10/13/16Biomarkers for hbv treatment response
10/06/16Cetp modulator for use in the treatement of eye disease
10/06/16Combination therapy for the treatment of ovarian cancer
10/06/16Process for the preparation of chiral 2-aryl morpholines
09/29/16Inhibitors of bruton's tyrosine kinase
09/29/16Synthesis of trans-8-chloro-5-methyl-1 -[4-(pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4h-2,3,5,10b-tetraaza-benzo[e]azulene and crytalline forms thereof
09/29/16Method for examining a plurality of cultured cells for the presence of periodic structures of at least one target component contained in the cultured cells
09/22/16Pharmaceutical composition
09/22/16Pyrazine derivatives
09/22/16Method for improving antibody stability
09/15/16Imidazole derivatives
09/15/16Octahydro-cyclobuta [1,2-c;3,4-c']dipyrrol-2-yl
09/15/16Substituted benzamides
09/15/16Specific detection of rat antibodies in mouse serum
09/08/16Combination therapy
09/08/16Benzazepine dicarboxamide compounds
09/08/16Anti-tim3 antibodies and methods of use
09/01/16Pyrido[4,3-b]pyrazine-2-carboxamides as neurogenic agents for the treatment of neurodegenerative disorders
09/01/16Single b-cell cultivation method
09/01/163d adcc nk facs assay
08/25/162-phenyl or 2-hetaryl imidazol[1,2-a]pyridine derivatives
08/25/16Genetic markers for predicting responsiveness to therapy
08/18/16Process to manufacture n-[(3s)-1-[4-[(3-fluorophenyl)methoxy]phenyl]-5-oxo-pyrrolidin-3-yl]acetamide
08/18/16Novel 6-amino acid heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
08/18/16Novel pyrazine compounds for the treatment of infectious diseases
08/18/16Cation and anion exchange chromatography method
Social Network Patent Pack
08/11/16New phenyl-dihydropyridine derivatives as aldosterone synthase inhibitors
08/11/16Novel aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection
08/04/16Combination therapy of antibodies against human csf-1r and tlr9 agonist
08/04/16Diazacarbazole derivatives as tau-pet-ligands
08/04/16Phenyl-dihydropyridine derivatives as inhibitors of aldosterone synthase
08/04/164-amino-imidazoquinoline compounds
07/28/16Moveable chromatography column separator
07/21/16Indol and indazol derivatives
07/21/16Ethynyl derivatives
07/21/16Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis b virus infection
Patent Packs
07/21/16Imidazo[1,2-a]pyridin-7-amine
07/21/16Pyrazolo[1,5a]pyrimidine derivatives as irak4 modulators
07/21/16T cell activating bispecific antigen binding molecules
07/21/16Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides
07/21/16Apparatus for leak detection
07/14/16Cap for a container
07/14/16New process
07/14/16Novel indazoles for the treatment and prophylaxis of respiratory syncytial virus infection
07/14/16Antigen binding molecules comprising a tnf family ligand trimer
07/07/16Pyrrolopyridine or pyrazolopyridine derivatives
07/07/16Novel 3-substituted 5-amino-6h-thiazolo[4,5-d]pyrimidine-2,7-dione compounds for the treatment and prophylaxis of virus infection
07/07/16Fc-receptor binding modified asymmetric antibodies and methods of use
06/30/16Indole-carboxamides
06/30/16Urea derivatives and their use as fatty-acid binding protein (fabp) inhibitors
06/30/16Method for the production of a glycosylated immunoglobulin
06/23/16Combination therapy of tumor-targeted il-2 variant immunocytokines and antibodies against human pd-l1
06/23/16Co-crystals of 5-amino-2-oxothiazolo[4,5-d]pyrimidin-3(2h)-yl-5-hydroxymethyl tetrahydrofuran-3-yl acetate and methods for preparing and using the same
06/16/16Novel triazolo[4,5-d]pyrimidine derivatives
06/16/16Therapeutic fusion protein
06/09/16Novel aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection
06/09/16Human fcrn-binding modified antibodies and methods of use
06/09/16Combination therapy of anti-her3 antibodies
06/09/16Trimeric antigen binding molecules
06/09/16Device for use in the detection of binding affinities
06/02/16Fcrn-binding abolished anti-igf-1r antibodies and their use in the treatment of vascular eye diseases
05/26/16Compounds for treating spinal muscular atrophy
05/26/16Method for differentiation of pluripotent stem cells into multi-competent renal precursors
05/19/16Stable intravenous formulation
05/19/16Novel pyridine derivatives
05/19/161,7-naphthyridine derivatives
Patent Packs
05/19/16Amino acid sequence presenting fusion polypeptide and its use
05/19/16Device for use in the detection of binding affinities
05/12/16Combination of ro5503781 and capecitabine for cancer therapy
05/12/16Combination of ro5503781, capecitabine and oxaliplantin for cancer therapy
05/12/16Ethynyl derivatives
05/12/16Method for the selection of a long-term producing cell
05/05/16Novel 6,7-dihydrobenzo[a]quinolizin-2-one derivatives for the treatment and prophylaxis of hepatitis b virus infection
05/05/16Novel 6-bridged heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
04/14/16Bace1 inhibitors
04/14/16Optimizing the production of antibodies
04/07/16Indolin-2-one or pyrrolo-pyridin/pyrimidin-2-one derivatives
03/31/16Synthesis of bace inhibitors
03/24/16Novel tetrazolone derivatives
03/24/16Novel processes for the manufacture of propane-1-sulfonic acid (3-[5-(4-chloro-phenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl)-amide
03/24/16Novel 6-fused heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
03/24/16Promoter
03/17/16Combined drug administration of dalcetrapib and orlistat
03/17/16New 3,4-dihydro-2h-isoquinoline-1-one and 2,3-dihydro-isoindol-1-one compounds
03/17/16New 3,4-dihydro-2h-isoquinoline-1-one and 2,3-dihydro-isoindol-1-one compounds
03/17/16New 3,4-dihydro-2h-isoquinoline-1-one and 2,3-dihydro-isoindol-1-one compounds
Social Network Patent Pack
03/17/16Bispecific t cell activating antigen binding molecules
03/17/16Specific detection of rat antibodies in mouse serum
03/10/16Novel aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection
03/10/16Sequence dependent aggregation
03/10/16Fc-receptor binding modified asymmetric antibodies and methods of use
03/03/16New aryl-quinoline derivatives
02/25/16Combination therapy for proliferative disorders
02/25/16Bace1 inhibitors
02/25/16Novel 4-methyl-dihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
02/25/16Antibodies against human csf-1r and uses thereof
02/18/16Combination therapy of antibodies activating human cd40 and antibodies against human pd-l1
02/18/16Isoquinoline derivatives
02/18/16Pd-catalyzed coupling of pyrazole amides
02/18/16Purine derivatives as cb2 receptor agonists
02/18/16Pyrrolo[2,3-d]pyrimidine derivatives as cb2 receptor agonists
02/11/16Arylethynyl derivatives
02/04/16Radiolabeled compounds
01/28/16Dimeric compounds
01/21/16Piperazino[1,2-a]indol-1-ones and [1,4]diazepino[1,2-a]indol-one
01/21/16Novel pyridine derivatives
Social Network Patent Pack
01/14/16Antiviral compounds
01/14/16Cell penetrating peptides which bind irf5
01/14/16Complex of bi-specific antibody and digoxigenin conjugated to a therapeutic or diagnostic agent
01/14/16Oligomers and oligomer conjugates
01/07/16Antiviral compounds
01/07/16Urea derivatives and their use as fatty-acid binding protein (fabp) inhibitors
01/07/16Comt inhibitors
01/07/16Antiviral compounds
01/07/16Inhibitors of bruton's tyrosine kinase
01/07/16New dihydroquinoline-2-one derivatives
01/07/16Inhibitors of bruton's tyrosine kinase
01/07/16Anti-her3 antibodies binding to the beta-hairpin of her3
01/07/16Her1 antigen binding proteins binding to the beta-hairpin of her1
12/31/15Antiviral compounds
12/31/15Inhibitors of bruton's tyrosine kinase
12/31/15Fluoro-[1,3]oxazines as bace1 inhibitors
12/31/15Dihydroquinoline-2-one derivatives
12/31/15Novel pyrazol derivatives
12/31/15New octahydro-pyrrolo[3,4-c]-pyrrole derivatives and analogs thereof as autotaxin inhibitors
12/31/15Use of an amino acid auxotrophy cured prokaryotic strain for the recombinant production of a polypeptide
12/24/15Antiviral compounds
12/24/15New bicyclicpyridine derivatives
12/24/15Lna oligonucleotide carbohydrate conjugates
12/17/15New process
12/10/15Blood plasma biomarkers for bevacizumab combination therapies for treatment of breast cancer
12/10/15Antiproliferative benzo [b] azepin-2-ones
12/10/15Antiviral compounds
12/10/15Thiazole derivatives as inhibitors of bruton's tyrosine kinase
12/10/15New bicyclic derivatives
12/10/15Antibody formulation
Social Network Patent Pack
12/10/15Method for differentiation of pluripotent stem cells into cardiomyocytes
12/03/15Pyridine-2-amides useful as cb2 agonists
12/03/15Disulfide-linked multivalent mhc class i comprising multi-function proteins
11/26/15Process for the preparation of a dpp-iv inhibitor
11/26/15Method for preparing an outer surface of a planar waveguide to be capable of binding target samples along a plurality of predeterminded lines and a planar waveguide
11/19/15Substituted triazole boronic acid compounds
11/12/151,3-oxazines as bace1 and/or bace2 inhibitors
11/12/15Oxytocin receptor agonists for the treatment of cns diseases
11/12/15Blood brain barrier shuttle
11/12/15Anti-human igg1 antibody
11/05/15Substituted isoxazole amine compounds as inhibitors of scd1
11/05/15Process for the preparation of a fluorolacton derivative
11/05/15Multispecific antibodies
10/29/15Chitosan covalently linked with small molecule integrin antagonist for targeted delivery
10/29/15Novel pyridine derivatives
10/29/15Antiviral compounds
10/29/15Novel pyridine derivatives
10/22/15Substituted triazole and imidazole compounds
10/22/15Pyridine-2-amides useful as cb2 agonists
10/22/154-amino-imidazoquinoline compounds
10/22/15Novel pyrazine derivatives as cb2 receptor agonists
10/22/15Co2 profile cultivation
10/15/15Inhibitors of bruton's tyrosine kinase
10/15/15Inhibitors of bruton's tyrosine kinase
10/15/15Process for the preparation of 2-trifluoromethyl isonicotinic acid and esters
10/15/15Method for the production and selection of molecules comprising at least two different entities and uses thereof
10/08/15Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2
10/08/15Inhibitors of syk
10/08/152-oxo-2,3-dihydro-indoles for the treatment of cns disorders







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