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Hutchinson
Hutchinson Technology Incorporated

Hutchinson patents


Recent patent applications related to Hutchinson. Hutchinson is listed as an Agent/Assignee. Note: Hutchinson may have other listings under different names/spellings. We're not affiliated with Hutchinson, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "H" | Hutchinson-related inventors


 new patent  Compositions for cellular immunotherapy

The present disclosure relates to compositions and methods for using cells having cellular immunotherapies comprising a composition of chimeric antigen receptor (car)-modified cd4+ t cells and a composition of cd8+ t cells modified with a distinct car in that the intracellular signaling component of the each car is different, wherein the modified cd4+ and cd8+ t cells have enhanced helper and effector functions, respectively, and together more effectively augment the immune response. Such cellular immunotherapies are useful in treating disease, such as cancer.. ... Hutchinson

Elastomer composition for an insert for supporting a wheel tyre, insert comprising the composition and mounted assembly incorporating the insert

The invention concerns an elastomer composition for a self-supporting insert (1) intended to support a tyre of a wheel of a vehicle, an insert of which at least one layer (3) comprises said composition and a mounted assembly incorporating said insert. The invention applies to a non-pneumatic mounted assembly, in particular for a vehicle with two wheels, in which each of the tyres is permanently supported by said insert, the elastomer composition comprises, principally by mass, a mixture of at least one first thermoplastic elastomer and at least one second thermoplastic elastomer, and said composition is such that said at least one first thermoplastic elastomer is a copolyamide (copa) and said at least one second thermoplastic elastomer is a thermoplastic styrene (tps) elastomer.. ... Hutchinson

Methods for identifying and using inhibitors of casein kinase 1 epsilon isoform for inhibiting the growth and/or proliferation of myc-driven tumor cells

In one aspect, the invention provides a method for inhibiting the growth and/or proliferation of a myc-driven tumor cell comprising the step of contacting the tumor cells with a csnk1ε inhibitor. In another aspect, the invention provides a method of treating a subject suffering from a tumor comprising myc-driven tumor cells, comprising administering to the subject an amount of a composition comprising a csnk1ε inhibitor effective to inhibit the growth and/or proliferation of the tumor cells.. ... Hutchinson

Biomarkers and uses thereof for selecting pancreas cancer intervention

The instant disclosure provides methods for using biomarkers for identifying therapeutic regimens to treat pancreas cancer, or to reduce the risk of pancreas cancer, pancreas cancer metastasis, pancreas cancer proliferation, or pancreas cancer recurrence. For example, such therapeutic regimens can be based on the level of runx3 expression in the context of a particular dpc4 genotype, or based on the level of runx3 expression in combination with the level of col6a1 expression, spp1 expression or both. ... Hutchinson

High aspect ratio electroplated structures and anisotropic electroplating processes

Devices including high-aspect ratio electroplated structures and methods of forming high-aspect ratio electroplated structures are described. A method for manufacturing metal structures includes providing a substrate having a metal base characterized by a height to width aspect ratio a/b and electroplating a metal crown on the base to form the metal structure with a height to width aspect ratio a/s greater than the aspect ratio a/b of the base.. ... Hutchinson

Modified stem cells and uses thereof

Stem cells are modified to express an extracellular component including a tag cassette. The tag cassette can be used to detect, enrich, isolate, activate, track, deplete, or eliminate modified cells. ... Hutchinson

Run seal for vehicle window and sealing module incorporating means for guiding the window in the seal and an element of the door frame

The present invention concerns an elastomer run seal suitable for receiving a sliding window of a motor vehicle side door, and a sealing module comprising said seal, said window and means for guiding the window rigidly connected to the window in order to slidingly guide same in an offset manner in a groove of the seal. Said seal (1) is suitable for receiving a window (v) mounted laterally flush with an outer surface of a vertical edge element of a frame (2) of the door adjacent to the window chosen from an upright of the frame and a vertical outer trim (2a) provided on the frame, the seal comprising at least one ascending strand and one top strand, said ascending strand having an outer branch (12) to be mounted in sealing contact with the vertical element and the window, an inner branch (11) to be mounted on the frame and a connecting branch (13), the seal comprising a groove (12a) receiving, in a vertically sliding manner, means (10) for guiding the window rigidly connected to the inner face (vi) of same. ... Hutchinson

Disk drive suspension assembly having a partially flangeless load point dimple

Various embodiments concern a suspension assembly of a disk drive. The suspension assembly includes a load beam comprising a major planar area formed from a substrate. ... Hutchinson

Dynamic imbalanced force generator and an actuator comprising such a generator

A dynamic imbalanced force generator includes a pair of eccentric masses and a shaft frame. The generator further includes at least one support plate of a motor arranged radially with respect to the shaft frame, and a gear system. ... Hutchinson

Cocal envelope pseudotyped retroviral vector producer cells

Producer cell lines that produce cocal envelope pseudotyped retroviral vectors are described. The producer cells can be grown and can produce the cocal envelope pseudotyped retroviral vectors in large scale serum-free suspensions.. ... Hutchinson

Composite panel with thermosetting cellular matrix, manufacturing method, and structure for covering a wall formed from an assembly of panels

A composite panel with a thermosetting cellular matrix, a method for manufacturing said panel, and a structure for covering a wall that is formed from an assembly of such panels. The structure provides the wall with heat insulation against cryogenic fluids and/or protection against fire or flames and/or sealing against the fluids. ... Hutchinson

Compositions and methods for target nucleic acid molecule enrichment

The present disclosure relates to methods of detecting mutations in a target nucleic acid molecule by amplifying a target sequence to contain adaptor sequences and allowed for the product to be directly sequenced using high throughput dna sequencing technology.. . ... Hutchinson

Engineered and multimerized human immunodeficiency virus envelope glycoproteins and uses thereof

Multimerized human immunodeficiency virus (hiv) envelope glycoproteins are described. The envelope glycoproteins are multimerized engineered and multimerized human immunodeficiency virus (hiv) envelope glycoproteins are described. ... Hutchinson

Chemically sharpening blades

A method for forming a cutting tool includes masking a metal base with one or more masks, the one or more masks including at least one variable permeability mask, and chemically etching the masked metal base to form a blade of the cutting tool.. . ... Hutchinson

04/12/18 / #20180100808

On-axis and diffuse illumination for inspection systems

An inspection system is described. The inspection system includes a camera and a housing. ... Hutchinson

04/05/18 / #20180094180

Heat storage material

The invention relates to a material including a support consisting of a porous composite material including at least one polymer phase forming a binder based on at least one polymer selected from thermoplastic polymers, elastomers, and elastomer thermoplastics, and at least one filler selected from thermally conductive fillers, the pores of the support consisting of the porous composite material being partially or entirely filled with at least one phase-change material. The invention also relates to a method for producing said material.. ... Hutchinson

03/29/18 / #20180085406

Compositions and methods for providing hematopoietic function without hla matching

The present invention relates to methods and compositions for providing hematopoietic function in immunodeficient human patients, by selecting an expanded human umbilical cord blood stem/progenitor cell sample without taking into account the hla-type of the expanded human cord blood stem/progenitor sample or the hla-type of the patient; and administering the selected expanded human cord blood stem/progenitor cell sample to the patient. Methods for obtaining the expanded human cord blood stem/progenitor cell samples, banks of frozen expanded human cord blood stem/progenitor cell samples, and methods for producing such banks are also provided herein.. ... Hutchinson

03/22/18 / #20180080078

Method of identifying human compatible t cell receptors specific for an antigenic target

Methods are provided for identifying t cell receptors that specifically bind a particular antigenic target and can be used as therapeutics against disease.. . ... Hutchinson

03/15/18 / #20180075870

Partial curing of a microactuator mounting adhesive in a disk drive suspension

Various embodiments concern a method of attaching a microactuator to a flexure, depositing a wet mass of structural adhesive on the flexure, mounting the microactuator on the wet mass of structural adhesive, partially curing the mass of structural adhesive through a first application of curing energy, and depositing a mass of conductive adhesive on the flexure. The mass of conductive adhesive is deposited in contact with the mass of structural adhesive. ... Hutchinson

03/15/18 / #20180073015

Method of measuring adaptive immunity

A method of measuring immunocompetence is described. This method provides a means for assessing the effects of diseases or conditions that compromise the immune system and of therapies aimed to reconstitute it. ... Hutchinson

03/08/18 / #20180068684

Disk drive suspension baseplate having enhanced torque retention and method of manufacture

A system and methods for manufacturing disk drive suspension baseplates are described. Disk drive suspension baseplates having boss outer surfaces characterized by roughness parameters ra≧0.15 μm.. ... Hutchinson

03/08/18 / #20180068683

Multilayer disk drive motors having out-of-plane bending

Various embodiments concern a gimbaled flexure having a dual stage actuation structure. The flexure comprises a gimbal on which a motor is mounted. ... Hutchinson

03/08/18 / #20180066282

Cocal vesiculovirus envelope pseudotyped retroviral vectors

Provided herein are cocal vesiculovirus envelope pseudotyped retroviral vectors that exhibit high titers, broad species and cell-type tropism, and improved serum stability. Disclosed cocal vesiculovirus envelope pseudotyped retroviral vectors may be suitably employed for gene therapy applications and, in particular, for the ex vivo and in vivo delivery of a gene of interest to a wide variety of target cells.. ... Hutchinson

03/01/18 / #20180063438

Dual camera assemblies with optical image stabilization

A camera lens assembly is described. The camera lens assembly includes a plurality of optical image stabilization assemblies. ... Hutchinson

03/01/18 / #20180061442

Low resistance ground joints for dual stage actuation disk drive suspensions

A stainless steel dual stage actuated disk drive head suspension baseplate including a plated electrical contact area having nickel and gold. The baseplate can be heat treated. ... Hutchinson

02/22/18 / #20180052299

Camera lens suspension with enhanced auto focus electrical interconnects

A camera lens assembly is described. The camera lens assembly includes a support member. ... Hutchinson

02/15/18 / #20180044404

Immunomodulatory fusion proteins and uses thereof

The present disclosure relates to immunomodulatory fusion proteins containing an extracellular binding domain and an intracellular signaling domain, wherein binding of a target can generate a modulatory signal in a host cell, such as a t cell. The present disclosure also relates to uses of immune cells expressing such immunomodulatory fusion proteins to treat certain diseases, such as cancer or infectious disease.. ... Hutchinson

02/08/18 / #20180037953

Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing

Methods are provided for predicting a subject's infection status using high-throughput t cell receptor sequencing to match the subject's tcr repertoire to a known set of disease-associated t cell receptor sequences. The methods of the present invention may be used to predict the status of several infectious agents in a single sample from a subject. ... Hutchinson

02/01/18 / #20180031073

Hydraulic antivibrating device

Vibration damping device comprising two frames and an elastomer body that connects frames together and which delimits a first hydraulic chamber that communicates with a second hydraulic chamber that can be deformed by a constricted passage. An electromagnetic actuator, that controls the vibration damping behaviour of the device, comprises a suction cup with a permanent magnet.. ... Hutchinson

02/01/18 / #20180031072

Hydraulic antivibrating device

Vibration damping device comprising two frames and an elastomer body that connects armatures together and which delimits a first hydraulic chamber that communicates with a second hydraulic chamber that can be deformed by a constricted passage. A sealed box, integral with the second frame, contains a control device and an actuator. ... Hutchinson

02/01/18 / #20180030153

Compositions and methods to modify cells for therapeutic objectives

The present disclosure provides compositions and methods that rapidly and selectively modify cells of the immune system to achieve therapeutic objectives. The methods can be practiced in vivo and any cell type that expresses a known marker can be targeted for a therapeutic objective.. ... Hutchinson

02/01/18 / #20180029703

Vtol aerodyne with supporting axial blower(s)

Disclosed is an aerodyne including a supporting structure, to which are connected: at least one supporting axial blower, attached to the supporting structure; at least one main engine driving the supporting blower; at least three attitude blowers controlling roll and pitch, each attitude blower having an electrical motor and being attached, respectively, to one of the elongate arms that are distributed in a laterally, outwardly projecting manner around the supporting structure, to which each arm is connected by an inner end portion, the axis of rotation of each attitude blower being attached relative to the supporting structure, and all the attitude blowers being located outside the space centrally occupied by the supporting blower; at least one battery for supplying power to the electrical motors of the attitude blowers; a landing gear attached under the supporting structure; and a nacelle for holding the battery and a payload.. . ... Hutchinson

01/18/18 / #20180017195

Device for coupling a rigid male endpiece to a flexible female pipe, and production method therefor

The invention relates to a fluid-transfer coupling device designed to couple a rigid male endpiece (30) to a flexible female pipe (20) and to the production method therefor. The device comprises: a sleeve (10) for gripping around the pipe and locking the endpiece, the sleeve having a radially inner part (18) surrounding an annular sealing lining (50) mounted in abutment on the endpiece; and a metal socket (40) having a tubular portion (41) gripped by the pipe and ending in a collar formed by a radial step (43) which extends in an axial end (44) and has a radial height, the axial end being mounted inside and in contact with the radially inner part and forming the base of a groove receiving the lining, the device comprising means for fitting the sleeve to the collar and comprising a continuous peripheral projection (13) formed in one piece with the sleeve. ... Hutchinson

01/18/18 / #20180017194

Composite seal for rapid fluid-transfer coupling, and coupling of this type

The invention relates to a composite annular seal (30) having a flexible body and rigid reinforcement (35) for a rapid fluid-transfer coupling (1), and to a rapid coupling of this type incorporating the seal. The seal (30) with a reinforcement (35) can be used for a coupling comprising a female tubular sleeve (10) and a male tubular endpiece (20) mounted inside the sleeve in order to produce overall static sealing between a recess (13) in the sleeve (10) and the endpiece (20), the seal comprising: an inner axial wing (31) having a radially inner face (31a) which has a radially innermost flexible peripheral portion (31aa) designed to be applied tightly against the endpiece; an outer axial wing (36) having a flexible radially outer face (36a) which is designed to be placed firmly against the recess; and a core (33) connecting the inner wing to the outer wing. ... Hutchinson

01/11/18 / #20180012621

Disk drive head suspension structures having improved gold-dielectric joint reliability

A disk drive head suspension or flexure and method of manufacture. Embodiments include a portion such as a terminal pad or flying lead comprising a base layer, a dielectric layer on the base layer, a conductor layer, a seed layer between the dielectric layer and the conductor layer, and a noncorrosive metal layer on the seed layer side of the conductor layer. ... Hutchinson

01/11/18 / #20180008684

Compositions, methods and uses for alpha-1 antitrypsin or derivatives thereof

Embodiments herein report methods and compositions for treating or preventing adverse effects of radiation therapies. In certain embodiments, compositions and methods relate to reducing or inhibiting damage due to acute, periodic or chronic radiation exposure.. ... Hutchinson

01/04/18 / #20180005655

Process coupons used in manufacturing flexures

A system and methods for manufacturing devices such as flexures using process coupons are described are described. The method including performing a test on at least one feature of a coupon, the coupon is included on an assembly sheet used in manufacturing flexures. ... Hutchinson

01/04/18 / #20180005653

Co-located gimbal-based dual stage actuation disk drive head suspension with non-parallel motors

Embodiments of disk drive head suspensions are described that include a spring metal layer. The spring metal layer includes a base region, support arms extending from the base region, and a slider mounting region. ... Hutchinson

01/04/18 / #20180003282

Uncoupling pulley with offset clutch

Uncoupling pulley having a longitudinal axis, and including a wheel rim having a first zone, to receive a belt connecting the wheel rim to a first power transmission element, and second zone situated in the axial extension along the direction defined by the longitudinal axis of the pulley, of the first zone; a hub to be secured to a second power transmission element; one of the power transmission elements being driving, and the other being driven; a ring mounted below the second zone of the wheel rim and around the hub, so the ring can rotate, around the longitudinal axis, relative to the wheel rim and/or the hub; an elastically deformable element mounted between the hub and the ring; and a unidirectional clutch having an end fastened to the ring and the remaining part of which is mounted below the second zone of the wheel rim and above the ring.. . ... Hutchinson

12/28/17 / #20170368357

Metallized components and surgical instruments

A surgical instrument and related methods are described. The surgical instrument includes a first jaw including a first structural jaw element and a first sealplate fixed to the first structural jaw element and a second jaw including a second structural jaw element and a second sealplate fixed to the second structural jaw element. ... Hutchinson

12/21/17 / #20170362653

Characterization of adaptive immune response to vaccination or infection using immunosequencing

Methods of monitoring and measuring dynamic adaptive immune cell responses are provided. High-throughput sequencing of t cell receptor and immunoglobulin loci is used to characterize the breadth of an effector cell response to a stimulus, such as a vaccine or infection. ... Hutchinson

12/21/17 / #20170362298

Enhanced affinity t cell receptors and methods for making the same

The present disclosure provides methods for generating enhanced affinity t cell receptors by agonist selection of hematopoietic progenitor cells expressing an antigen specific tcrα cultured with stromal cells expressing delta-like-1 or delta-like-4, compositions prepared from such methods, and uses of thereof.. . ... Hutchinson

12/14/17 / #20170357076

Shape memory alloy wire attachment structures with adhesive for a suspension assembly

Embodiments of the disclosure include a suspension assembly having a support member, a moving member movably coupled to the support member, and shape metal alloy wires coupled between the support and moving members by attachment structures. According to various embodiments, the attachment structures include at least one of: an adhesive disposed proximate to a side of the attachment structures and between the attachment structures.. ... Hutchinson

11/23/17 / #20170336646

Camera lens suspensions

An assembly includes a support structure including attach structures. The suspension assembly includes a moving structure including attach structures and flexure arms configured to couple the moving structure to the support structure, the flexure arms are configured to enable movement of the moving structure with respect to the support structure. ... Hutchinson

11/23/17 / #20170335391

Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from a large number of samples

The invention is directed to methods for highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune heterodimers from a large number of biological samples containing lymphocytes of interest. Methods of the invention comprise performing a single pairing assay on a pool of source samples to determine nucleic acids encoding paired cognate receptor heterodimer chains in the combined pool. ... Hutchinson

11/23/17 / #20170335386

Method of measuring adaptive immunity

Compositions and methods for measuring adaptive immune receptor (t cell receptor and immunoglobulin) diversity are described, and find uses for assessing immunocompetence and other purposes. Means are provided for assessing the effects of diseases or conditions that compromise the immune system and of therapies aimed to reconstitute it. ... Hutchinson

11/16/17 / #20170330699

Conductive electrodes and their manufacturing process

Electrode for storing electrical energy including a metal current collector and an active material, the current collector being coated on at least one portion of one of its faces with at least one protective layer placed between the current collector and the active material, the protective layer including: (a) a polymer matrix including: (a1) at least one cross-linked epoxy polymer or copolymer, (a2) at least one elastomer, and (b) conductive fillers. This system is used in aqueous electrolyte supercapacitors, the protective layer allowing a very significant reduction in corrosion problems that are generally associated with the use of aqueous electrolytes to be achieved and the adhesion of the active material to the metal collector to be improved.. ... Hutchinson

11/16/17 / #20170330589

Co-located gimbal-based dsa disk drive suspension with traces routed around slider pad

A suspension having a dsa structure on a gimbaled flexure includes a loadbeam and a flexure attached to the loadbeam. The flexure includes a metal layer with a pair of spring arms, a tongue including a slider mounting surface, and a pair of struts connecting the pair of spring arms to the tongue. ... Hutchinson

11/09/17 / #20170323658

Piezoelectric disk drive suspension motors having plated stiffeners

Various embodiments concern a gimbaled flexure having a dual stage actuation structure. The flexure comprises a gimbal on which a motor is mounted. ... Hutchinson

11/09/17 / #20170322216

Pancreatic cancer diagnostic

The present disclosure provides methods of using certain biomarker expression profiles in the detection, diagnosis, prognosis, or development of treatment regimens for various cellular hyperproliferative disorders of the pancreas. For example, methods comprise detecting whether the concentration of erbb2, esr1, and tnc in a test biological sample from a subject is elevated as compared to a control.. ... Hutchinson

09/21/17 / #the invention relates to an anti-vibration device (100), for example intended for a railroad application, comprising:

Hutchinson

. . ... Hutchinson

09/21/17 / #20170267756

Tagged chimeric effector molecules and receptors thereof

The present disclosure relates to tagged chimeric effector molecules and receptor molecules thereof for genetically engineering a host cell, wherein the recombinant host cell can be identified, isolated, sorted, induced to proliferate, tracked or eliminated using the tag. An exemplary receptor molecule is a chimeric antigen receptors (cars) having an extracellular domain comprising a binding domain for a target, a hinge region and a tag cassette, a hydrophobic portion as a transmembrane domain and, an intracellular part with an effector domain. ... Hutchinson

09/14/17 / #20170260584

Cell population analysis using single nucleotide polymorphisms from single cell transcriptomes

The disclosure provides methods and systems for producing single cell rna sequencing data. Single nucleotide polymorphisms (snps) identified in such data can be used to distinguish subpopulations of cells within a mixed population.. ... Hutchinson

08/31/17 / #20170246279

Compositions and methods for boosting the efficacy of adoptive cellular immunotherapy

The present disclosure provides compositions and methods for boosting, augmenting or enhancing the efficacy of the adoptive cellular immunotherapy by using modified t cells expressing an antigen binding protein in conjunction with modified cells (such as hematopoietic progenitor cells, modified human immune system cells or a combination thereof) expressing the antigen specifically bound by the antigen binding protein of the modified t cells.. . ... Hutchinson

08/03/17 / #20170219842

Camera assembly

A camera assembly comprises a lens assembly (20) supported on a support structure (4), wherein the lens assembly includes an autofocus actuator arrangement (24) and the camera assembly includes an optical image stabilization assembly (40) arranged to move the lens assembly in a plane perpendicular to the optical axis. A flexible printed circuit tape (103) connected between the support structure (4) and the lens assembly (20) and providing an electrical connection to the auto-focus actuator arrangement (24) is bent around a corner, thereby allowing the flexible printed circuit tape (103) to accommodate the motion of the lens assembly perpendicular to the optical axis. ... Hutchinson

08/03/17 / #20170219443

Miniature pressure/force sensor with integrated leads

A pressure/force sensor comprises a diaphragm structure including a sensing element and a lead structure extending from the diaphragm structure and including first and second traces electrically coupled to the sensing element. The diaphragm structure and the lead structure include a circuit assembly comprising a common insulating layer and a common conductor layer on the insulating layer. ... Hutchinson

07/13/17 / #20170197839

Gelled aqueous polymer composition, pyrolysed carbonated composition produced therefrom for a supercapacitor electrode, and methods for the production thereof

The invention relates to a gelled aqueous polymer composition for forming, by means of drying then pyrolysis, a monolithic porous carbon, to a pyrolysed carbonated composition produced by the drying, followed by the pyrolysis, of said gelled composition, to a porous carbon electrode for a supercapacitor comprising said pyrolysed composition, and to methods for producing said respectively gelled and pyrolysed compositions. A gelled composition according to the invention, produced from the polycondensation of polyhydroxybenzene(s) and hexymethylenetetramine, is such that the hexymethylenetetramine comprised therein represents a mass fraction of between 7% and 15% inclusive. ... Hutchinson

06/22/17 / #the present invention relates to a flexible composite organic aerogel (1) comprising:

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. . ... Hutchinson

06/15/17 / #the present invention relates to a vacuum insulation board (1) comprising:

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. . ... Hutchinson

06/08/17 / #20170162218

Two-motor co-located gimbal-based dual stage actuation disk drive suspensions with motor stiffeners

Various embodiments concern a dual stage actuation flexure. The dual stage actuation flexure comprises a flexure having a gimbal. ... Hutchinson

06/08/17 / #20170160559

Integrated camera lens suspension

A camera lens suspension assembly in comprises a support member including a support metal base layer formed as single piece of metal, a moving member including a moving metal base layer formed as a single piece of metal, a plurality of bearings and smart memory alloy wires. The support member includes a bearing plate portion, a plurality of static wire attach structures, and a plurality of mount regions, all formed from or on the support metal base layer. ... Hutchinson

05/11/17 / #20170131562

Camera lens suspension with integrated electrical leads

Embodiments of the invention include a camera lens optical image stabilization suspension assembly having a support member, a moving member movably coupled to the support member, and smart metal alloy wires coupled between the support and moving members. The moving member includes flexure arms that have integrated conductive traces.. ... Hutchinson

04/27/17 / #20170117009

Piezoelectric disk drive suspension motors having plated stiffeners

Various embodiments concern a gimbaled flexure having a dual stage actuation structure. The flexure comprises a gimbal on which a motor is mounted. ... Hutchinson

04/27/17 / #20170117008

Multilayer disk drive motors having out-of-plane bending

Various embodiments concern a gimbaled flexure having a dual stage actuation structure. The flexure comprises a gimbal on which a motor is mounted. ... Hutchinson

04/27/17 / #20170113297

Metallizing polymers, ceramics and composites for attachment structures

A method of manufacture includes forming a metallized tie layer on a surface of a non-metallic component, positioning the surface of the non-metallic component to mate with a metallic surface of a second component, and joining the metallized tie layer with the mated metallic surface of the second component using metal to metal joining techniques.. . ... Hutchinson

04/27/17 / #20170112869

Compositions, kits, and methods to induce acquired cytoresistance using stress protein inducers

The present disclosure provides compositions, kits, and methods to protect organs by inducing acquired cytoresistance without causing injury to the organ. The compositions, kits, and methods utilize heme proteins, iron and/or vitamin b12 and, optionally, agents that impact heme protein metabolism.. ... Hutchinson

04/20/17 / #20170107493

Expansion and engraftment of stem cells using notch 1 and/or notch 2 agonists

The present disclosure provides methods for immortalizing precursor cells that are non-terminally differentiated cells such as stem cells, the methods comprising culturing the precursor cells in the presence of a notch 1 agonist, notch 2 agonist or notch 1 agonist and notch 2 agonist (and, in particular embodiments, one or more growth factors) that support the proliferation but not differentiation of the non-terminally differentiated cells. The present disclosure further provides methods to induce the differentiation of immortalized cells, comprising growing the cells in the presence of a notch 1 agonist, notch 2 agonist or notch 1 agonist and notch 2 agonist and at least one growth factor which supports the differentiation of the cell into a more specialized cell type. ... Hutchinson

04/06/17 / #20170098460

Disk drive suspension assembly having a partially flangeless load point dimple

Various embodiments concern a suspension assembly of a disk drive. The suspension assembly includes a load beam comprising a major planar area formed from a substrate. ... Hutchinson

03/30/17 / #20170088925

Thermo-mechanical stabilization of nitinol wires in an optical image stabilization suspension

A method and system for stabilizing properties of shape memory alloy (sma) wires in an optical image stabilization (ois) suspension of the type having a first or support assembly and a second or moving assembly coupled with respect to one another by the sma wires. Embodiments of the method comprise cyclically mechanically straining and de-straining the wires by moving the moving and support assemblies with respect to one another while heat is applied to the wires. ... Hutchinson

03/16/17 / #20170075192

Insulation of components of an sma actuation arrangement in a miniature camera

Insulation of components of an sma actuation arrangement in a miniature camera a miniature camera comprises an sma actuator arrangement including at least one sma actuator wire arranged to effect focus, zoom or optical image stabilization. At least one component of the sma actuator arrangement that is not the sma actuator wire is coated with an electrically insulating layer, thereby reducing the risk of short circuiting of the drive current of the sma actuator wire. ... Hutchinson

02/23/17 / #20170049809

Compositions and methods to modulate angiogenesis

The present invention provides methods of stimulating angiogenesis and the growth or migration of cells associated with angiogenesis, by contacting animals, tissues, or cells with sulfide, alone or in combination with nitric oxide. These methods may be used for a variety or purposes, including promoting wound healings, increasing blood flow, and for the treatment and prevention of diseases and disorders associated with decreased blood flow, including ischemic or hypoxic injury.. ... Hutchinson

02/02/17 / #20170033675

Active vibratory control device

Active vibratory control device comprising an armature, a movable element comprising a coil and mounted so as to be able to slide with respect the armature, a spring connecting the armature to the movable element. The armature comprises an electrical supply circuit and the spring comprises a conductive part that connects the electrical supply circuit to the coil.. ... Hutchinson

02/02/17 / #20170029574

Gelled, crosslinked and non-dried aqueous polymeric composition, aerogel and porous carbon for supercapacitor electrode and processes for preparing same

The invention relates to a gelled, crosslinked and non-dried aqueous polymeric composition capable of forming a non-monolithic organic aerogel by drying, to this aerogel, to a non-monolithic porous carbon resulting from a pyrolysis of this aerogel, to an electrode based on this porous carbon, and to a process for preparing this composition and this aerogel. The invention applies in particular to supercapacitors. ... Hutchinson

01/26/17 / #the invention relates to a process for preparing a gelled, dried composition forming a monolithic aerogel with a heat conductivity of less than or equal to 40 mw·m−1·k−1 and derived from a resin of polyhydroxybenzene(s) and formaldehyde(s), to this aerogel composition and to the use thereof. this process comprises:

Hutchinson

. . ... Hutchinson

01/26/17 / #20170025673

Cathode for a cell of a lithium-ion battery, its manufacturing process and the battery incorporating it

The invention relates to a cathode that is usable in a cell of a lithium-ion battery comprising an electrolyte based on a lithium salt and on a non-aqueous solvent, to a process for manufacturing this cathode and to a lithium-ion battery having one or more cells incorporating this cathode. This cathode is based on a polymer composition, obtained by melt processing and without solvent evaporation, that is the product of a hot compounding reaction between an active material and additives including a polymer binder and an electrically conductive filler. ... Hutchinson

01/26/17 / #20170023099

Power transmission belt

A power transmission belt and a method for manufacturing said belt. The belt includes: a backing layer made of a material with elastomeric behaviour; a ventral layer made of a material with elastomeric behaviour; a mechanical reinforcement means inserted between the backing layer and the ventral layer comprising a film with thermoplastic transformation surrounding the mechanical reinforcement means, said film comprising at least: a first component physically and/or chemically bonded to at least one component of the backing layer; a second component physically and/or chemically bonded to at least one component of the mechanical reinforcement means; and a third component physically and/or chemically bonded to at least one component of the ventral layer. ... Hutchinson

01/12/17 / #the present invention relates to a conductive electrode for a system for the storage of electrical energy (1) having an aqueous electrolyte solution, said electrode comprising a metal current collector (3) and an active material (7), said current collector (3) comprising at least one conductive protective layer (5) which is leaktight to electrolytes and which is placed between said metal current collector (3) and said active material (7), said conductive protective layer (5) comprising:

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. . ... Hutchinson

01/12/17 / #the invention relates to a gelled carbon-based composition forming an organic polymeric monolithic gel which is suitable for forming an aerogel by drying, to uses and to a process for preparing this carbon-based composition. the invention applies especially to the production of such gels having a very low density and a very low heat conductivity, a very high specific surface area and a satisfactory compression strength, for their use as thermal superinsulators or as carbon-based electrode precursors of supercondensers.

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. . ... Hutchinson

01/05/17 / #20170004854

Disk drive head suspension structures having improved gold-dielectric joint reliability

A disk drive head suspension or flexure and method of manufacture. Embodiments include a portion such as a terminal pad or flying lead comprising a base layer, a dielectric layer on the base layer, a conductor layer, a seed layer between the dielectric layer and the conductor layer, and a noncorrosive metal layer on the seed layer side of the conductor layer. ... Hutchinson








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