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Incept Llc patents


Recent patent applications related to Incept Llc. Incept Llc is listed as an Agent/Assignee. Note: Incept Llc may have other listings under different names/spellings. We're not affiliated with Incept Llc, we're just tracking patents.

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Wound healing using topical systems and methods

The present invention generally relates to compositions and methods for topical or transdermal delivery and treatment of wounds and/or promoting wound healing. In some cases, the composition may include nitric oxide and/or peptides such as thyrotropin-releasing hormone (trh) and/or gnrh (gonadotropin-releasing hormone). ... Incept Llc

Test tube rack of analyzer pipeline, shift detection method and device using the same

A test tube rack of an analyzer pipeline includes multiple test tube holders for holding test tubes. The test tube rack of an analyzer pipeline comprises a light blocker configured at a side wall of the test tube rack and across multiple test tube holders. ... Incept Llc

Rigid substrate, touch panel, and processing method of rigid substrate

A rigid substrate, a touch panel including the rigid substrate and a processing method of the rigid substrate are provided. The rigid substrate includes an ion strengthened surface layer completely covering the entire outer surface thereof. ... Incept Llc

Compositions and methods for increasing muscle growth

This disclosure is in the field of anti-activin receptor iib (actriib) antibodies. In particular, it relates to the use of said antibodies for treating muscle disorders, such as muscle wasting due to disease or disuse.. ... Incept Llc

Chimeric receptors and uses thereof in immune therapy

Disclosed herein are chimeric receptors comprising an extracellular domain with affinity and specific for the fc portion of an immunoglobulin molecule (ig), an fc-binding domain; a transmembrane domain; at least one co-stimulatory signaling domain; and a cytoplasmic signaling domain comprising an immunoreceptor tyrosine-based activation motif (itam). Also provided herein are nucleic acids encoding such chimeric receptors and immune cells expressing the chimeric receptors. ... Incept Llc

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05/17/18 / #iv. a polypeptide encoded by a nucleic acid that has at least 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99% or 100% identity to the mature polypeptide coding sequence of seq id no: 1.

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05/17/18 / #iii. a polypeptide encoded by a nucleic acid that hybridizes under medium stringency, preferably under high stringency conditions to the complementary strand of the mature polypeptide coding sequence of seq id no:1;

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05/17/18 / #ii. a polypeptide that has least 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% identity to the mature polypeptide sequence of seq id no: 2;

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05/17/18 / #i. a polypeptide comprising a mature polypeptide sequence of seq id no: 2;

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05/17/18 / #20180137496

Information processing device and information processing method

An electronic money server groups a parent who owns a parent mobile phone and children who own child mobile phones to be registered as a family, and credit information of the parent is also registered. When the child accesses the electronic money server by using the child mobile phone and specifies a money amount to request family charge, the electronic money server requests the parent mobile phone for permission of the family charge. ... Incept Llc

05/17/18 / #20180137487

System and method for geo-aware transportation billing verification

A geo-aware transportation verification system and is disclosed. A processor receives a billing request for payment, including an actual geolocation and an actual time and date. ... Incept Llc

05/17/18 / #20180137481

Method for providing a credit cardholder with multiple funding options

A method and a system for providing a payment cardholder with multiple funding source options for a payment card are provided herein. First, a managing platform associates at least two funding sources with the payment card. ... Incept Llc

05/17/18 / #20180137479

Secure system for implementing an international currency unit platform

As commerce has become more and more digitally based, the financial sector has become increasingly decoupled from the real sector. Filling the gap, the current interest-bearing debt system has shifted risk in an unsustainable manner that stands in contrast to a profit-loss-sharing arrangement. ... Incept Llc

05/17/18 / #20180137458

Method for monitoring and tracking identified material in fillable receptacles

A method for monitoring and tracking identified material in at least one fillable receptacle in at least one facility. The method includes installing at least one sensor with an ultrasonic transducer or a laser or both in one of the fillable receptacles, creating a customer profile with a fillable receptacle location, a quantity of fillable: receptacles and a preset height limit for each fillable receptacle, and activating the sensor to repeatedly transmit an ultrasonic signal or light pulse into the receptacles and calculate remaining empty space then comparing remaining empty space to the preset height limits to determine whether the fillable receptacle is full. ... Incept Llc

05/17/18 / #20180137444

Real-time method and system for assessing and improving a presence and perception of an entity

A method for assessing and improving a presence and perception of an entity includes, for one or more presence categories of data sources, determining a number of data sources in a presence category on which the entity has a presence to thereby determine a presence score for the entity. The presence score increases as the number of data sources upon which the entity has a presence increases. ... Incept Llc

05/17/18 / #20180137435

Information extraction support device, information extraction support method and computer program product

An information extraction support device includes a receptor, a pattern generator, a data generator, and an output controller. The receptor receives input of a first training example for learning a model used in at least one of extraction of information and extraction of a relation between a plurality of pieces of information, and clue information indicating a basis on which the first training example is used for learning. ... Incept Llc

05/17/18 / #20180137422

Fast low-memory methods for bayesian inference, gibbs sampling and deep learning

Methods of training boltzmann machines include rejection sampling to approximate a gibbs distribution associated with layers of the boltzmann machine. Accepted sample values obtained using a set of training vectors and a set of model values associate with a model distribution are processed to obtain gradients of an objective function so that the boltzmann machine specification can be updated. ... Incept Llc

05/17/18 / #20180137409

Method of constructing an artifical intelligence super deep layer learning model, device, mobile terminal, and software program of the same

A method for constructing an artificial intelligence super depth learning model includes inputting by an objective function to input into each node of an input layer by interposing a no-teacher machine learning, connecting the no-teacher machine learning mutually between each node of the input layer and a nerve layer, calculating output reference values based on a learning value obtained by the no-teacher machine learning, a trigger threshold of a cranial nerve, or a sampling learning value, and determining an excitation level according to output reference values of all the nerve layers.. . ... Incept Llc

05/17/18 / #20180137406

Efficient convolutional neural networks and techniques to reduce associated computational costs

The present disclosure provides systems and methods to reduce computational costs associated with convolutional neural networks. In addition, the present disclosure provides a class of efficient models termed “mobilenets” for mobile and embedded vision applications. ... Incept Llc

05/17/18 / #20180137390

Data object creation and recommendation using machine learning based online evolution

The technology disclosed relates to providing expanded data object correlations for user-generated web customizations. Roughly described, it relates to creating an initial plurality of candidate data object image representations by procreation, storing a candidate population having the plurality of candidate data object image representations, scoring each of the candidate data object image representations for conformity with a predefined goal using a trained neural network system and/or a rule-based percept filter, discarding candidate data object image representations from the candidate population, adding new data object image representations to the candidate population by procreation, iterating the scoring, the discarding, and the adding until the discarding yields a candidate pool of candidate data object image representations not yet discarded but which satisfy a convergence condition, and providing as recommendation for display to a user at least one of the data object images represented in the candidate pool.. ... Incept Llc

05/17/18 / #20180137387

Systems and methods for aligning sequences to graph references

Various embodiments of the disclosure relate to systems and methods for aligning a sequence read to a graph reference. In one embodiment, the method comprises selecting a first node from a graph reference, the graph reference comprising a plurality of nodes connected by a plurality of directed edges, at least one node of the plurality of nodes having a nucleotide sequence. ... Incept Llc

05/17/18 / #20180137370

Surveillance system using accurate object proposals by tracking detections

A surveillance system and method are provided. The surveillance system includes an image capture device configured to capture a video sequence of a target area that includes a set of objects and is formed from a set of image frames. ... Incept Llc

05/17/18 / #20180137310

Peripheral bus security interface and method

A security device for securing a peripheral link between a computing device and a peripheral comprising is interposed on the peripheral link, between said computing device and said peripheral. The security device queries an identifier of a peripheral, and imitating said peripheral to said computing device by way of a host port of said security device. ... Incept Llc

05/17/18 / #20180137303

Intercepting sensitive data using hashed candidates

An example system includes a processor to receive hashed sensitive data including attributes, a hashing function, and text classifiers. The processor is to also monitor a user interface and detect an input text or an output text. ... Incept Llc

05/17/18 / #20180137296

Providing containers access to container daemon in multi-tenant environment

An example system includes a plurality of containers associated with a plurality of tenants. The plurality of containers are to execute code in isolation for the associated plurality of tenants. ... Incept Llc

05/17/18 / #20180137286

Method and apparatus for security testing of application flows that cannot be automated through http replay

Technical solutions are described for testing a computer program product. An example method includes intercepting an instance of a request sent for execution by the computer program product, the request being one from a plurality of requests in a sequential flow. ... Incept Llc

05/17/18 / #20180137259

Device and method for adapting the use of an apparatus

A device for adapting the use of an apparatus is provided. The device has a processing unit for checking if a license for the apparatus exists and for producing a certificate request and a transmitting/receiving unit for transmitting the certificate request to a certification server and for receiving a certificate from the certification server in response to the certificate request. ... Incept Llc

05/17/18 / #20180137234

Computational design of self-assembling cyclic protein homo-oligomers

Described herein are polypeptides capable of self-assembling to form homo-oligomers, and methods for designing such polypeptides.. . ... Incept Llc

05/17/18 / #20180137203

Methods and systems for a content development and management platform

The present system and method relate to enhancements to online search engines and search result rankings, which can benefit from large scale analysis of online content (e.g., web pages) and vast amounts of information kept and processed from prior searches to develop intelligent associations between various content with one another. Some aspects employ machine learning systems and methods to further enhance the present goals. ... Incept Llc

05/17/18 / #20180137194

Apparatus and method for automated and assisted patent claim mapping and expense planning

An apparatus and computer implemented method that include obtaining, into a computer, text of a patent, automatically finding and extracting, using the computer, a set of claim text from the patent text, identifying, using the computer, text of independent claims from the set of claim text, displaying in a first row on a computer monitor the text of the independent claims, automatically determining a plurality of preliminary scope-concept phrases from the text of the independent claims, displaying in a second row on the computer monitor the text of the plurality of preliminary scope-concept phrases, eliciting and receiving user input to specify a first one of the plurality of preliminary scope-concepts phrases, and highlighting each occurrence of the specified first one of the plurality of preliminary scope-concept phrases in a plurality of the independent claims displayed in the first row. A scope concept builder tool is also provided.. ... Incept Llc

05/17/18 / #20180137184

Sql interceptor for use with third party data analytics packages

An sql interceptor inserted as a proxy between a database client and the corresponding database server intercepts a constrained application-generated sql query and composes a new data request. Parameter values in the sql query determine whether the new data request is sent to a database server or a web service provider. ... Incept Llc

05/17/18 / #20180137135

Systems and methods for categorizing web pages and using categorized web pages

Systems and methods for categorizing web pages and using categorized web pages are provided. The categorization involves using at least a master word list and one or more category word lists. ... Incept Llc

05/17/18 / #20180137132

Notification control system, server apparatus, communication terminal apparatus, computer program, and notification control method

A communication terminal apparatus, upon accepting a spoken instruction from a user, generates position data indicating a position of the user, and transmits the position data and audio data indicating the instruction to a server apparatus. The server apparatus discriminates a situation in which the user in possession of the communication terminal apparatus is placed, based on acquired data, and notifies content that satisfies a predetermined notification condition to the user. ... Incept Llc

05/17/18 / #20180137127

System and method for generating analytics for entities depicted in multimedia content

A system and method for generating analytics for entities depicted in multimedia content, including: identifying at least one social pattern based on social linking scores of a plurality of entities indicated in a social linking graph, wherein each social pattern is identified at least by comparing one of the social linking scores to a predetermined social pattern threshold, wherein each social linking score is generated based on contexts of at least one multimedia content element (mmce) in which at least two of the plurality of entities are depicted, wherein each context is determined based on a plurality of concepts of one of the at least one mmce, wherein each concept matches at least one signature generated for the at least one mmce above a predetermined threshold; and generating, based on the identified at least one social pattern, analytics for the plurality of entities depicted in the social linking graph.. . ... Incept Llc

05/17/18 / #20180137065

Method and apparatus for directly connecting dockee device to peripheral device in a wireless docking network

Disclosed is a method by a docking center of assisting communication between a dockee and a peripheral device to which the docking center is connected, including transmitting, as a group owner of a first group, to the dockee, information for a direct connection between the dockee and the peripheral device, receiving an assist request for setting the direct connection based on the information, transmitting a response indicating whether the assist request is accepted, receiving a release request for releasing a connections between the dockee and the docking center and between the docking center and the peripheral device, terminating control of the peripheral device, receiving a joining request for requesting to join a second group, transmitting a response for joining the second group as a client, the dockee being set as a second group owner, and operating as the group owner of the first group and the client of the second group.. . ... Incept Llc

05/17/18 / #20180137030

Automatic generation of an exception detector for determining an overflow condition

Systems and methods for automatic generation of an exception detector for determining an overflow condition are provided. In one example, a method including receiving code corresponding to at least one block of the hardware module, wherein the code providing at least a first value for a first variable, a second value for a second variable, or an operation to be performed using at least one of the first variable or the second variable, is provided. ... Incept Llc

05/17/18 / #20180137009

Executing computer instruction including asynchronous operation

Technical solutions are described for executing a computer instruction including an asynchronous operation. An example method includes computing parameters associated with the asynchronous operation, and transmitting a command for executing the asynchronous operation by an external device. ... Incept Llc

05/17/18 / #20180137002

Thread based dynamic data collection

Execution of a program in a plurality of threads is monitored. Responsive to identifying an exception triggered by the program execution in a first of the plurality of threads, a data collector can be dynamically created for the exception. ... Incept Llc

05/17/18 / #20180136899

Adaptive receiver

A nonlinear control system and a speaker protection system are disclosed. In particular, a control system for adapting an audio output from a speaker in the proximity of an object is disclosed. ... Incept Llc

05/17/18 / #20180136876

Consuming streamed data records

Aspects extend to methods, systems, and computer program products for consuming streamed data records. An application binds members (e.g., columns) of a structure (e.g., record) from a data source to memory buffers, and may specify one or more members be retrieved individually or be ignored entirely. ... Incept Llc

05/17/18 / #20180136862

System and method for storing data

A method for provisioning a volume of data is disclosed. The method involves identifying a set of rules associated with the volume of data, wherein the set of rules includes at least two conflicting rules, prioritizing the at least two conflicting rules, placing the volume of data on a first computer system according to the prioritization, collecting performance metrics corresponding to the placed volume of data, computing a score based on the collected performance metrics, determining if the computed score is acceptable, determining that the placement is successful if the computer score is determined to be acceptable, and changing the prioritization of the at least two conflicting rules and placing the volume of data on a second computer system according to the changed prioritization if the score is determined to be unacceptable.. ... Incept Llc

05/17/18 / #20180136847

Control device and computer readable recording medium storing control program

A control device configured to backup data updated in response to update requests issued by a plurality of host devices, includes a memory; and a processor configured to: record, in the memory, a reception interval and a last reception time of the update requests for each host device, compare an elapsed time from the last reception time to a certain timing and the reception interval at the certain timing for each host device, and start the backup according to a comparison result for each host device.. . ... Incept Llc

05/17/18 / #20180136831

Interactive user interfaces for location-based data analysis

Various systems and methods are provided that display various geographic maps and depth graphs in an interactive user interface in substantially real-time in response to input from a user in order to determine information related to measured data points, depth levels, and geological layers and provide the determined information to the user in the interactive user interface. For example, a computing device may be configured to retrieve data from one or more databases and generate one or more interactive user interfaces. ... Incept Llc

05/17/18 / #20180136823

System and method for provisioning a user interface for scaling and tracking

Methods and systems for interfacing with users may include displaying content associated with a plurality of user interface elements, tracking a view of the user on at least a portion of the content to determine an interest of the user, detecting the user in proximity to an information handling system, displaying the portion of content corresponding to the interest of the user on the information handling system, sharing the portion of content associated with the plurality of user interface elements on a display, and scaling the size of the portion of content on the display to match the size of the portion of content displayed on the information handling system. The sharing may be based on a gesture from the user. ... Incept Llc

05/17/18 / #20180136820

Computer readable non-transitory recording medium, information processing method and information processing apparatus

Operation performed by user about a displayed web content. And the program causes the computer to perform presenting selection information associated with the operation, the selection information corresponding to a position change of any of elements of the displayed web content of the displayed web content, the selection information being related to timing of the operation. ... Incept Llc

05/17/18 / #20180136803

Methods and systems for executing functions in a text field

Methods, systems, and/or devices for executing functions in a text field are described. In some embodiments, a method may comprise displaying a field in an application running on a client device and accepting entry of text containing a predefined combination of characters followed by a keyword into the field, where the keyword corresponds to a function to be performed. ... Incept Llc

05/17/18 / #20180136798

Method and system for multi-modal lineage tracing & impact assessment in a concept lineage data flow network

According to some embodiments, system and methods for representing nodes and data flows in a network are provided, comprising providing a hierarchical taxonomy for one or more concepts; providing one or more hierarchical taxonomies for one or more boundary types, wherein one or more values from each boundary type are combined to form a definition of a boundary; and associating the at least one concept and at least one boundary with a transmission of data between a first node and a second node, wherein the transmitted data is a data flow. Numerous other aspects are provided.. ... Incept Llc

05/17/18 / #20180136779

Display device

A display device configured to be connected to an information terminal, includes: a video reception unit that receives video information about a screen including a cursor from the information terminal; a touch panel that brings up the screen on display based on the video information received by the video reception unit and detects a touch position specified by a touch operation; and a transmission unit that transmits operation information in correspondence to the touch operation to the information terminal. The transmission unit transmits the operation information in a delay when the touch operation is performed continuously.. ... Incept Llc

05/17/18 / #20180136746

User notification method, handwritten data capture device, and program

A user notification method performed by a handwritten data capture device includes determining whether a pointing body is in a pen-up state or a pen-down state, and determining whether coordinate data of a pointing body on a touch sensor of the handwritten data capture device is stored in a first area of a memory. In response to determining that the coordinate data is stored in the first area of the memory and that the pointing body is in the pen-up state, making a first user notification, for example, by causing a led lamp to slowly flash a light green color. ... Incept Llc

05/17/18 / #20180136638

Systems and methods for dynamic groups in control systems

Technology is disclosed for controlling accessories with dynamic groups in control systems (the “technology”). A dynamic group is first created as a copy of a user's predefined group of control elements. ... Incept Llc

05/17/18 / #20180136634

Communication system and mobile terminal

A communication system is equipped with a mobile terminal and a controller of an industrial machine for forming a shaped product. Mutual communications are carried out between the controller and the mobile terminal. ... Incept Llc

05/17/18 / #20180136630

Device and method of controlling machine tool, to control synchronized operation of spindle axis and feed axis

A controller controlling a synchronized operation of spindle and feed axes. A positioning-motion control section of a spindle-axis control section calculates a first velocity command making a spindle axis perform a decelerated rotation at a variable deceleration lower than a maximum deceleration during an acceleration-varying time just after the spindle axis reaches an intermediate speed or just before the spindle axis reaches a target position, and making the spindle axis perform the decelerated rotation at the maximum deceleration during a time except for the acceleration-varying time; calculates a second velocity command making the spindle axis perform a decelerated rotation at a constant deceleration lower than the maximum deceleration after the spindle axis reaches the intermediate speed; and chooses either one, achieving a lower speed, of the first and second velocity command during a period when the spindle axis operates from the intermediate speed to reach the target position.. ... Incept Llc

05/17/18 / #20180136580

Semiconductive roller

A semiconductive roller is provided which includes a roller body including a tubular inner layer of an inner layer elastic material containing a softener, and an outer layer of an outer layer elastic material provided on an outer periphery of the inner layer. The outer layer elastic material has a swelling percentage of not higher than 1% as measured when the outer layer elastic material is immersed in the softener at 100° c. ... Incept Llc

05/17/18 / #20180136507

Liquid crystal device, methods for manufacturing a liquid crystal device, and methods for operating a liquid crystal device

Provided are a liquid crystal device, a method for manufacturing a liquid crystal device, and a method for operating a liquid crystal device. According to the inventive concept, a method for manufacturing a liquid crystal device includes preparing a precursor solution including a monomer, liquid crystal molecules, a first dye, a second dye, and a third dye, and performing a polymerization process of the precursor solution to form a liquid crystal layer. ... Incept Llc

05/17/18 / #20180136434

Image sensor module with auto focus control

The present disclosure describes image sensor modules that can include auto focus control. The modules also include features that can help reduce or eliminate tilt of the module's optical sub-assembly with respect to the plane of the image sensor. ... Incept Llc

05/17/18 / #20180136416

Optical transceiver

An optical transceiver according to an embodiment is an optical transceiver that is engageable with an mpo connector in a longitudinal direction, and includes: a housing having a first inner surface on an inner side thereof and made of a metal; and an mpo receptacle that has a receptacle main body that has a first outer surface and is made of a metal, and a latch that determines a position of the receptacle main body which is perpendicular to the longitudinal direction with respect to the housing, and that is engaged with the mpo connector. The receptacle main body is fixed to the housing such that the first outer surface of the receptacle main body comes into close contact with the first inner surface of the housing.. ... Incept Llc

05/17/18 / #20180136366

Distributed solar energy prediction imaging

Concepts of distributed solar energy prediction imaging are described. In one embodiment, a solar forecast system includes a computing environment, a network, and an imaging device. ... Incept Llc

05/17/18 / #20180136364

Light curtain safety system

A system to detect obstacles includes a power beam transmission circuit, a power beam reception circuit arranged to receive a power beam from the power beam transmission circuit, an emitter module, and a detector module arranged to distinguish between a first characteristic and a second characteristic. The emitter module includes a first emitter arranged to emit a first signal having the first characteristic, the first signal emitted in proximity to the power beam, and a second emitter arranged to emit a second signal having the second characteristic, the second characteristic different from the first characteristic, the second signal emitted in proximity to the first signal. ... Incept Llc

05/17/18 / #20180136296

Rf coil elements with split dc loops for magnetic resonance imaging systems for integrated parallel reception, excitation, and shimming and related methods and devices

Systems, methods and devices are configured for integrated parallel reception, excitation, and shimming (ipres) with rf coil elements with split dc loops. Parallel transmit/receive (which can include b1 shimming and/or parallel imaging capabilities) and b0 shimming employ the same set of localized coils or transverse electromagnetic (tem) coil elements, with each coil or tem element working in both an rf mode (for transmit/receive and b1 shimming) and a direct current (dc) mode (for b0 shimming) simultaneously. ... Incept Llc

05/17/18 / #20180136286

Method for determining a potential of an anode and/or a potential of a cathode in a battery cell

The invention relates to a method for determining a potential (p1) of an anode (21) and/or a potential (p2) of a cathode (22) in a battery cell (2) which has a negative terminal (11) and a positive terminal (12), having the following steps:—measuring a current (i) flowing through the battery cell (2),—determining a charge transfer resistance of the battery cell (2),—ascertaining a charge transfer resistance (rct1) of the anode (21) and/or a charge transfer resistance (rct2) of the cathode (22) from the charge transfer resistance,—ascertaining an idle voltage of the battery cell (2),—ascertaining a depth of discharge of the battery cell (2) from the idle voltage,—ascertaining an anode residual voltage (u1) and/or a cathode residual voltage (u2) from the depth of discharge of the battery cell (2),—ascertaining an anode excess potential (n1) from the charge transfer resistance (rct1) of the anode (21) and the current (i) and/or ascertaining a cathode excess potential (n2) from the charge rct2 transfer resistance (rct2) of the cathode (22) and the current (i), and—ascertaining the potential (p1) of the anode (21) from the anode residual voltage (u1) and the anode excess potential (n1) and/or ascertaining the potential (p2) of the cathode (22) from the cathode residual potential (u2) and the cathode excess potential (n2).. . ... Incept Llc

05/17/18 / #20180136267

Magnetic field based wireless gmd/emp-e3 impact monitoring device

A system and methods for monitoring an impact of geomagnetic disturbances (gmds) or an e3 component of electromagnetic pulses (emp-e3), involving a transducer generating a transduced signal in response to a magnetic field of a current carrying element of a transmission line. The transduced signal reflects harmonic characteristics of the current carrying element, and is amplified and filtered, then digitally converted. ... Incept Llc

05/17/18 / #20180136246

Device, instrument, and method for inductive heating of a sample for analyte detection

Induction heating can be used facilitate reactions within biological samples. A sample container can be placed in a magnetic field from an induction coil to generate heat. ... Incept Llc

05/17/18 / #20180136235

Method for determining the risk of developing alzheimer's disease

The present invention relates to an in vitro method for determining the risk of developing alzheimer's disease or a cognitive disorder similar to said disease, an in vitro method for designing a personalized therapy in a subject suffering from mild cognitive impairment and an in vitro method for selecting a patient susceptible to be treated with a therapy for the prevention and/or treatment of alzheimer's or a cognitive disorder similar to said disease based on determining, in a sample from the subject, the level of phosphorylation in threonine residues in e2f4 protein or in a functionally equivalent variant. The invention also relates to the use of e2f4 or a functionally equivalent variant thereof, wherein the e2f4 or variant is phosphorylated in threonine as a marker of the risk of developing alzheimer's disease or a cognitive disorder similar to alzheimer's disease. ... Incept Llc

05/17/18 / #20180136232

Citrullinated proteins: a post-translated modification of myocardial proteins as marker of physiological and pathological disease

Disclosed herein are methods for diagnosing cardiovascular disease. The methods comprise detection of citrullinated proteins and/or citrullinated peptides. ... Incept Llc

05/17/18 / #20180136225

Method and kit for detection of anti-zika virus antibodies

Provided is a method of detecting the presence of an anti-zika virus (zikv) antibody in a sample, including contacting a sample with a suspension having a plurality of microspheres wherein individual microspheres are conjugated to a peptide and the peptide includes a zikv peptide selected from the group including zikv ns1, zikv ns5, and zikv envelope protein, forming a first incubated suspension by incubating said sample with said suspension to permit binding of anti-zikv antibodies present in the sample to said microspheres, forming a second incubated suspension by contacting said first incubated suspension with an anti-zikv antibody detecting-reagent to permit binding of the anti-zikv antibody detecting reagent to said microspheres, removing from the second incubated suspension anti-zikv antibody detecting-reagent molecules that are not bound to said microspheres, and detecting the presence of anti-zikv antibody detecting-reagent molecules in the second incubated suspension. Also provided is a kit containing reagents and compositions for performing the foregoing method.. ... Incept Llc

05/17/18 / #20180136224

Pneumococcal serotypes

Disclosed is a new and emerging serotype of streptococcus pneumoniae designated serotype 6c, and assays and monoclonal antibodies useful in identifying same. Also disclosed is a novel pneumococcal polysaccharide with the repeating unit {→2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→3) ribitol (5→phosphate}. ... Incept Llc

05/17/18 / #20180136220

Correlated peptides for quantitative mass spectrometry

Described herein are methods for identifying signature peptides for quantifying a polypeptide of interest in a sample. The methods include cleaving the polypeptide into peptides; detecting a multiplicity of the peptides with a quantitative analytical instrument; comparing the linearity of signals attributable to pairs of the peptides in a multiplicity of samples; and selecting signature peptides from a group of peptides with more highly correlated signals.. ... Incept Llc

05/17/18 / #20180136218

Secreted protein acidic and rich in cysteine (sparc) protein srm/mrm assay

The current disclosure provides for specific peptides, and derived ionization characteristics of the peptides, from the secreted protein acidic and rich in cysteine (sparc) protein that are particularly advantageous for quantifying the sparc protein directly in biological samples that have been fixed in formalin by the method of selected reaction monitoring (srm) mass spectrometry, or what can also be termed as multiple reaction monitoring (mrm) mass spectrometry. Such biological samples are chemically preserved and fixed wherein said biological sample is selected from tissues and cells treated with formaldehyde containing agents/fixatives including formalin-fixed tissue/cells, formalin-fixed/paraffin embedded (ffpe) tissue/cells, ffpe tissue blocks and cells from those blocks, and tissue culture cells that have been formalin fixed and or paraffin embedded. ... Incept Llc

05/17/18 / #20180136216

Biomarkers for a combination therapy comprising lenvatinib and everolimus

Biomarkers are provided that predict whether a human subject having a renal cell carcinoma is in need of a combination therapy comprising lenvatinib or a pharmaceutically acceptable salt thereof (e.g., lenvatinib mesylate) and everolimus. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for and treating a subject having, suspected of having, or at risk of developing a renal cell carcinoma.. ... Incept Llc

05/17/18 / #20180136213

Methods for diagnosing diseases associated with human signal peptide-containing molecules

The invention provides human signal peptide-containing proteins (hspp) and polynucleotides which identify and encode hspp. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. ... Incept Llc

05/17/18 / #20180136207

Peptides of m. tuberculosis for a screening test for hiv positive patients at high-risk for tuberculosis

Provided are peptides suitable for early detection of active m. Tuberculosis (mtb) infection in immunocompromised individuals. ... Incept Llc

05/17/18 / #20180136197

Cell-free methods of detecting bioactive ligands

The present disclosure as disclosed in various embodiments is related to a bioassay for rapid screening and detection of bioactive ligands and screening for potential pharmaceuticals. In various embodiments are disclosed cell-free methods, systems, and kits for detecting bioactive ligands such as endocrine disrupting chemicals or nuclear hormone receptor modulators in a biological or environmental sample or for screening compounds for potential pharmaceutical application such as potential nuclear hormone receptor modulator pharmaceuticals.. ... Incept Llc

05/17/18 / #20180136188

Method of assessing drying depth of cementitious material

The present invention relates to the field of material determination or analysis, and provides a method of assessing drying depth of cementitious materials including the following steps: preparing a plurality of cementitious material specimens; drying the cementitious material specimens; conducting electrochemical impedance spectrum measurement on each cementitious material specimen; accordingly determining a model for analyzing the drying depth of the cementitious material specimen. The method of assessing drying depth of the cementitious material provided by the present invention takes the influence of the resistivity changes on the model into consideration, and the drying depth of the cementitious material is reflected and reckoned with regularly changes of the electrochemical parameters, not only increasing the accuracy but also saving much testing labor, time and cost.. ... Incept Llc

05/17/18 / #20180136186

Water quality analysis device

Provided is a water quality analysis device capable of keeping the device in a clean state without leaving an operation at the time of device power supply activation to an operator and without wasting time and wash water. The water quality analysis device is configured such that: a memory 21 capable of storing a stored content in a cut-off state of the device power supply is provided; the states of the vessels, such as an ic reactor 1 and a tc reactor 2, in which sample water is injected at the time of an analysis operation are sequentially stored in the memory 21; contents of the memory 21 are read at the time of the device power supply activation; and a cleaning operation is automatically executed according to prescribed procedures with the states read for each reactor 1 and 2 as a starting point. ... Incept Llc

05/17/18 / #20180136164

Systems and methods to extract target material from a gel

A device, system, and method of extracting a target component from a gel. A gel processing system comprises a gel excision and fragmentation device with a cutting edge shaped to cut a sample containing a targeted component from a gel, a receptacle shaped to receive the gel sample, and a fragmentation membrane to fragment the gel sample coupled to a receiving container. ... Incept Llc

05/17/18 / #20180136160

Ion-selective electrode systems and methods utilizing same

Ises comprising a substrate layer; a carbon nanotube layer disposed on the substrate layer; a conductive metal layer on a portion of the carbon nanotube layer; a conductive polymer disposed on the portion; and an ion-selective membrane disposed on the conductive polymer and methods of making them are provided. A system is also provided for detecting a plurality of analyte ions in a sample comprising a housing; a plurality of ises associated with the housing, each electrode comprising an ion-selective membrane to a different analyte ion; a reference electrode associated with the housing; a fluid sample receptacle associated with the housing and in fluid communication with the plurality of ion-selective electrodes and reference electrode.. ... Incept Llc

05/17/18 / #20180136105

Method and system for estimating empirical snow depth

Disclosed is a system for estimating a snow depth including: an optical disdrometer for acquiring information on diameters of snow particles and particle number concentration; a laser snow depth gauge for measuring the height of snow accumulated through a laser beam type sensor to provide an observed stop depth; an estimated snow depth equation calculator for determining an optimal index for the diameters of the snow particles provided by the optical disdrometer, substituting the optimal index for a snow depth calculation equation as a first mathematical equation to calculate a computed snow depth, obtaining correlation between the observed snow depth and the computed snow depth, and calculating a regression equation between the observed snow depth and the computed snow depth as an estimated snow depth equation; and a snow depth estimator for estimating the snow depth on the basis of the estimated snow depth equation, and the first mathematical equation.. . ... Incept Llc

05/17/18 / #20180136082

Parametric trending architecture concept and design

A method for foreign object debris detection in a gas turbine engine may comprise receiving, by a controller, a plurality of master configuration parameters, receiving, by the controller, a plurality of individual configuration parameters in response to the plurality of master configuration parameters, receiving, by the controller, a first time-series data from a database, pre-processing, by the controller, the first time-series data to generate a second time-series data, implementing, by the controller, an anomaly detector model, the anomaly detector model configured to generate a third time-series data, and implementing, by the controller, a foreign object debris (fod) damage model, the fod damage model receiving the third time-series data. The pre-processing the first time-series data, the implementing the anomaly detector model, and the implementing the fod damage model may be defined by the plurality of individual configuration parameters.. ... Incept Llc

05/17/18 / #20180136048

Temperature estimation device and temperature estimation method for contactless power-reception device

A charging controller (25) acquires the power loss of a power transmission coil (31) from a power supply device (100) via wireless communication. A temperature estimation unit (33) estimates the ambient temperature of a power reception coil on the basis of a preset amount of heat generation of a power reception device (200) and the power loss of the power transmission coil (31). ... Incept Llc

05/17/18 / #20180136024

Ultrasonic meter

An ultrasonic meter detects a flow rate of a fluid. The ultrasonic meter has a fluid inlet, a fluid outlet and a flow passage connecting the fluid inlet to the fluid outlet. ... Incept Llc

05/17/18 / #20180136002

Driving assistant system

Driving assistant systems and computer-implemented methods for improving landmark-based route guidance are provided. The computer-implemented method includes receiving, by a processor, image data including one or more landmarks. ... Incept Llc

05/17/18 / #20180136001

Driving assistant system

Driving assistant systems and computer-implemented methods for improving landmark-based route guidance are provided. The computer-implemented method includes receiving, by a processor, image data including one or more landmarks. ... Incept Llc

05/17/18 / #20180135972

Using map information to smooth objects generated from sensor data

The technology relates to generating a representation of an object detected by a perception system of a vehicle. For instance, a set of data points corresponding to an object is received from the perception system. ... Incept Llc

05/17/18 / #20180135945

Rifle scope targeting display adapter mount

This disclosure describes a compact and lightweight rifle scope display adapter configured to be affixed in front of the objective lens of a rifle scope. The display adapter includes a receptacle that enables the adapter to be electrically connected to a ballistic computer, rangefinder or other targeting mechanism. ... Incept Llc

05/17/18 / #20180135828

A custom printed lamp shade

The present invention generally concerns a custom lampshade with a digital print. More specifically, the lamp shade includes an end cap that joins with printing substrates capable of passing light. ... Incept Llc

05/17/18 / #20180135783

Threaded coupling end for a percussion drill string component

A threaded coupling for a drill string component includes a body on which is formed a thread. A reduction in stress concentrations and a resistance to bending moments are achieved at the thread by reducing a thread depth at at least one axial end of the thread and by arranging an endmost flank of a crest or root of the thread at an endmost helical turn.. ... Incept Llc

05/17/18 / #20180135768

Check valve

A check valve includes a hollow, cylindrical body including inlets through a bottom, a receptacle on a center of the bottom with the inlets therearound, an o-ring mounted on an outer surface of the body, and a seat on a joining portion of the bottom of the body and an inner surface of the body; a flexible disc including a flat on one surface and a peg extending from a center of the other surface, the peg being disposed in the receptacle to secure the disc to the body wherein an edge of the other surface of the disc is rested upon the seat; and a hollow, cylindrical guide secured to the body, the guide including a stem urging against a center of the flat, and outlets through an end to communicate with inside of the body. The inlets are blocked by the disc in a closed position.. ... Incept Llc

05/17/18 / #20180135760

Aircraft gap seal

An aircraft assembly including: first and second external skin panels having opposing edge faces separated by a gap, the gap having a width in a first direction extending between the opposing edge faces and a depth in a second direction generally orthogonal to the first direction; and a gap seal arranged in the gap to at least partially fill the gap, wherein the gap seal is formed of a material configured such that compression of the gap seal in the first direction results in substantially no expansion of the gap seal in the second direction.. . ... Incept Llc

05/17/18 / #20180135670

Method and system for interconnecting structural panels

A panel may be configured with panel mounts by forming a panel connector accepting slot in the panel and then locating connector mounts in the slot. In another embodiment, a panel may be configured with panel connector mounts by milling a panel to leave areas of panel material which form the mounts and milling the panel behind to connector mounts to define areas for accepting portions of the panel connector. ... Incept Llc

05/17/18 / #20180135634

Fan with connector powered by mobile device

A fan powered by a mobile device is provided comprising an l-shaped body, a motor within the body, fan propeller blades attached one end of the l-shaped body, and a connector protruding from the other end of the l-shaped body that is capable of being inserted into a mobile device port in order to draw power from the mobile device. The l shaped body is bent at an angle between 45 and 135 degrees and or can be bent at a 90 degree right angle. ... Incept Llc

05/17/18 / #20180135516

Scavenge methodologies for turbine engine particle separation concepts

A method for scavenging small particles from a turbine engine includes directing compressed air through a flowpath, downstream of a compressor, which causes a reduction in a radial flow component and the introduction of or an increase in an axial flow component of the compressed air, removing a portion of the compressed air from the flowpath and directing the portion into a scavenge plenum, the scavenge plenum being positioned adjacent to and radially outward from the flow path, and returning the portion of the compressed air from the plenum to the flowpath while maintaining a majority of the small particles that were present in the portion within the scavenge plenum. Further, the method includes removing the majority of small particles from the plenum. ... Incept Llc

05/17/18 / #20180135455

Foreign object debris trending concept and design

A system and method for detecting foreign object debris damage is disclosed. A method for foreign object debris detection in a gas turbine engine may include receiving, by a controller, a first time-series data from a database, wherein the first time-series data comprises a feature, pre-processing, by the controller, the first time-series data to generate a second time-series data, generating a third time-series data via an anomaly detector model, sending, by the controller, the third time-series data to a foreign object debris (fod) damage model, and determining, by the controller, that a fod event has occurred based on data received from the fod damage model. ... Incept Llc

05/17/18 / #20180135415

Stress reduction dimples for circular holes

A method of reducing stress concentration in a material subjected to a predominant stress in a direction parallel to an axial plane defined through an axis of a circular cylindrical hole in the material between a first material surface and a second material surface, the material having a material thickness defined between the first material surface and the second material surface, the method comprising: forming a first proximal recess in the first material surface on the axial plane having a depth less than the material thickness, the first proximal recess having an outer edge spaced a first proximal dimension in the axial plane from a first rim of the hole; and forming a second proximal recess in the second material surface on the axial plane having a depth less than the material thickness, the second proximal recess having an outer edge spaced a second proximal dimension in the axial plane from a second rim of the hole, wherein the first proximal dimension on the first material surface is diametrically opposite, relative to the hole, to the second proximal dimension on the second material surface.. . ... Incept Llc

05/17/18 / #20180135393

Methods for microbially enhanced recovery of hydrocarbons

Methods for the recovery of geological hydrocarbons from hydrocarbon reservoirs include injecting a low molecular weight oil soluble hydrocarbon compound and an electron acceptor into a reservoir, which enter a region of the reservoir comprising a microbial culture capable of metabolizing the low molecular weight hydrocarbon compound and the electron acceptor, thereby promoting flow of geological hydrocarbon.. . ... Incept Llc

05/17/18 / #20180135323

Formation aids for use in forming swimming pools and associated method

A formation aid, for use in the forming of receptacles in a swimming pool, includes a three-dimensional body having an essentially conical shape. The three-dimensional body of the formation aid includes a narrow end, for placement near an interior edge of the swimming pool during formation of the swimming pool; and a wide end, for placement remote from the interior edge of the swimming pool, in order to form a receptacle.. ... Incept Llc

05/17/18 / #20180135304

Passive skylight dome configured to increase light collection at low sun elevation angles and to reduce light at high sun elevation angles

The present subject matter comprises a simple, passive skylight dome with relatively tall partially vertical sides comprising partially transparent material which diffuses the transmitted light, and a mostly opaque sun shade near the top of the relatively tall partially vertical sides. The partially vertical sides are able to better intercept sunlight from low sun elevation angles than conventional horizontal skylights. ... Incept Llc

05/17/18 / #20180135285

Toilet monitoring and intelligent control

A toilet monitor uses a toilet tank water level sensor producing a toilet tank water level measurement signal. A processor detects rate of change of the measurement signal and conditionally produce a responsive actuation signal in response to the detected rate of change. ... Incept Llc

05/17/18 / #20180135281

Sanitary coupling

A sanitary coupling (1) is provided that connects an inflow-side and an outflow-side line section to each other. A sanitary insert element (5) is provided that has an insert housing (4) and is insertable via an end-side insert opening into a housing receptacle (7) of a first line section (2). ... Incept Llc

05/17/18 / #20180135208

All-steel card clothing

A card clothing wire (1) for use on drums in carding machines has a base (2) and a blade (3) formed on the base, the base and blade having a total height of the wire (h1) of 1.5 mm to 5 mm. The blade (3) has teeth (4), wherein each tooth (4) includes a first tooth tip (5) having a tooth depth (h6) of 0.3 mm to 1.0 mm; a tooth pitch (p) of 1.4 mm to 2.5 mm; a back face with a back angle (γ1) of 50 to 80 angle degrees; and a tooth front face with a working angle (α). ... Incept Llc

05/17/18 / #20180135200

Heat dissipation system comprising a unitary graphene monolith

A unitary graphene layer or graphene single crystal containing closely packed and chemically bonded parallel graphene planes having an inter-graphene plane spacing of 0.335 to 0.40 nm and an oxygen content of 0.01% to 10% by weight, which unitary graphene layer or graphene single crystal is obtained from heat-treating a graphene oxide gel at a temperature higher than 100° c., wherein the average mis-orientation angle between two graphene planes is less than 10 degrees, more typically less than 5 degrees. The molecules in the graphene oxide gel, upon drying and heat-treating, are chemically interconnected and integrated into a unitary graphene entity containing no discrete graphite flake or graphene platelet. ... Incept Llc

05/17/18 / #20180135172

Susceptor, epitaxial growth device, and epitaxial wafer

Provided is a susceptor, capable of preventing occurrence of deep scratches on the back surface and beveled part of a wafer attributable to contact with lift pins or the susceptor, and reducing dust generation from the susceptor. A susceptor according to one embodiment of this disclosure includes a susceptor main body, and arc-shaped members. ... Incept Llc

05/17/18 / #20180135166

Epitaxial growth device, production method for epitaxial wafer, and lift pin for epitaxial growth device

An epitaxial growth device includes; a chamber; a susceptor; a supporting shaft, having a main column located coaxially with the center of the susceptor and supporting arms; and a lift pin, at least the surface layer region of the lift pin is made of a material having a hardness lower than the susceptor, the lift pin has a straight trunk part upper region configured to pass through the through-hole of the susceptor and having a surface roughness of from not less than 0.1 μm to not more than 0.3 μm, and the lift pin has a straight trunk part lower region configured to pass through the through-hole of the supporting arm and having a surface roughness of from not less than 1 μm to not more than 10 μm.. . ... Incept Llc

05/17/18 / #20180135134

Targeted selection of patients for treatment with cortistatin derivatives

A method for the targeted selection and treatment of patients with a tumor or cancer, comprising (i) determining whether the patient has a runx1 pathway impairment; and if so (ii) administering an effective amount of a cortistatin or its pharmaceutically acceptable salt or oxide, optionally in a pharmaceutically acceptable composition.. . ... Incept Llc

05/17/18 / #20180135121

Pore-forming protein conjugate compositions and methods

The present disclosure relates to compositions and methods based on a fast, efficient chemical reaction for conjugating a pore-forming protein, such as α-hemolysin, to a biomolecule, such as antibodies, receptors, and enzymes, such as dna polymerase, and the use of such pore-forming conjugates in nanopore devices and methods.. . ... Incept Llc

05/17/18 / #20180135095

Antibacterial polypeptide libraries and methods for screening the same

Compositions and methods for isolating polypeptides having antibiotic activity are provided. In some aspects, bacterial cell populations are provided that express a surface-displayed library of candidate polypeptide sequences under the control of an inducible promoter.. ... Incept Llc

05/17/18 / #20180135093

Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing

A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. ... Incept Llc

05/17/18 / #20180135092

Expression sequences

An isolated nucleic acid encoding a leader, which has a specific sequence, an isolated leader peptide encoded by such nucleic acid, an expression cassette comprising such nucleic acid encoding a leader operably linked to a nucleic acid sequence encoding a poi, a recombinant yeast host cell or a vector comprising such expression cassette, a method of producing a poi in such yeast host cell, and further the use of the specific nucleic acid for the secretion of a poi from a host cell and/or to increase the secretion of a poi from a host cell.. . ... Incept Llc

05/17/18 / #20180135069

Isolated polynucleotides and polypeptides for increasing plant yield and/or agricultural characteristics

Provided are isolated polynucleotides which comprise a nucleic acid sequence at least 80% identical to seq id no: 321, 1-320, 322-480, 793-2945 or 2946; isolated polypeptides which comprise an amino acid sequence at least 80% homologous to seq id no: 517, 481-516, 518-792, 2947-4662 or 4663, nucleic acid constructs comprising same, transgenic cells and plants expressing same and methods of using same for increasing yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, abiotic stress tolerance, and/or nitrogen use efficiency of a plant.. . ... Incept Llc

05/17/18 / #20180135060

Escherichia coli t7 expression vector, vectors for the co-expression and co-purification of recombinant peptides in/with carrier proteins, use of expression vectors for obtaining complexes with multiple antigens and immonomodulators

The present invention relates to a vector for the expression of recombinant proteins, antigens, pathogen-like particles and immunogenic complexes, said vector (pmrka vector) being produced by modifying the plasmids containing the gene sequence of the t7 promoter of e. Coli, this modification being mainly characterized by the substitution of the ampicillin-resistance gene by the kanamycin-resistance gene, and by the insertion of the par sequence (partition sequence which determines the efficient segregation of the plasmids in daughter cells during cell division). ... Incept Llc

05/17/18 / #20180135053

Method of stimulating tlr9-activated immune response

A method of stimulating a tlr9-activated immune response or enhancing a tlr9-activated immune response to an antigen is disclosed herein. Tlr9 is the cellular receptor for cpg-odn, and current developed cpg-odn has low activity to rabbit tlr9. ... Incept Llc

05/17/18 / #20180135051

Therapeutic oligomers for treating amyloidosis

This invention provides pharmaceutical compositions containing a una oligomer targeted to ttr and a pharmaceutically acceptable carrier. The compositions can be used in methods for treating or preventing ttr-related amyloidosis in a primate. ... Incept Llc

05/17/18 / #20180135046

Small-interfering rna expression systems for production of small-interfering rnas and their use

A method of preparing a library of small interfering rna (sirna) expression systems for producing sirna for silencing of target genes by inducing degradation of target gene rna expression products includes: (i) isolating rna of one or more target genes from a cell population; (ii) generating rna fragments from the isolated rna; (iii) converting the rna fragments into dsdna fragments; and (iv) cloning the dsdna fragments into vectors for forming cloned vectors, each vector including one or more promoters and at least one restriction enzyme site capable of accepting the insertion of at least one dsdna fragment such that sirna can be produced. Methods for producing sirna from the sirna expression system and methods of identifying a functional target gene for treatment by using the sirna produced from the sirna expression system and for identifying rnai therapeutics are also provided.. ... Incept Llc

05/17/18 / #20180135037

Thermophilic and thermoacidophilic metabolism genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods

Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering metabolism in a cell using isolated and/or purified polypeptides and nucleic acid sequences from alicyclobacillus acidocaldarius.. ... Incept Llc

05/17/18 / #20180135036

Use of polypeptides having protease activity in animal feed and detergents

The present invention relates to the use of isolated polypeptides having protease activity in animal feed and detergents. It also relates to the use of isolated nucleic acid sequences encoding the proteases in the recombinant production of isolated polypeptides having protease activity and isolated nucleic acid sequences encoding the proteases. ... Incept Llc

05/17/18 / #20180135035

Polypeptides having xylanase activity and polynucleotides encoding same

The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.. ... Incept Llc

05/17/18 / #20180135022

Method for producing artificial syncytiotrophoblast and progenitor cell thereof

According to the present invention, there is provided a method for producing artificial trophoblasts derived from human cells, that includes the steps of: adhesion culturing human pluripotent stem cells in a culture medium containing a bmp signal transduction activator, and during the culturing bringing the cells under culturing into contact with at least one selected from the group consisting of a γ aminobutyric acid b receptor activator, a peroxisome proliferator-activated receptor γ activator, a retinoid x receptor activator, and a retinoic acid receptor activator, thereby obtaining a culture containing trophoblasts differentiated from the human pluripotent stem cells, and so on.. . ... Incept Llc

05/17/18 / #20180135016

Chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease

The invention provides a chimeric receptor comprising nkg2d, dap10 and cd3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of nk cells. ... Incept Llc

05/17/18 / #20180135015

Chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease

The invention provides a chimeric receptor comprising nkg2d, dap10 and cd3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of nk cells. ... Incept Llc

05/17/18 / #20180135014

Chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease

The invention provides a chimeric receptor comprising nkg2d, dap10 and cd3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of nk cells. ... Incept Llc

05/17/18 / #20180135013

Chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease

The invention provides a chimeric receptor comprising nkg2d, dap10 and cd3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of nk cells. ... Incept Llc

05/17/18 / #20180135010

Isolation and long-term culturing of estrogen receptor-positive human breast epithelial cells

The present invention describes methods for long-term culturing of erpos cells, cell lines, and/or cell strains with exetended lifespan and/or cell strain as well as culture medium compositions. The invention further describes methods for isolating cells which may be used as starting point for long-term culturing of erpos cells, cell lines, and/or cell strains with extended lifespan and/or cell strain. ... Incept Llc

05/17/18 / #20180134986

Phospholipase c

A process for degumming a vegetable oil comprising contacting a vegetable oil comprising phospholipids with a polypeptide having phospholipase c activity of the invention or a composition of the invention, wherein phospholipids are hydrolysed into diacylglycerol and phosphate ester and/or phosphate, separating the phosphate ester and/or phosphate from the vegetable oil wherein a degummed vegetable oil is obtained.. . ... Incept Llc

05/17/18 / #20180134973

Method for on-line imaging of mesophase particles

On-line detection of mesophase particles employs a laser diode light source to illuminate a target area with a pulsed laser linearly or circularly polarized probe beam. Analysis of images determines extent of presence the birefringent mesophase particles, which are precursors to coking in catalytic hydrocracking processes. ... Incept Llc

05/17/18 / #20180134951

Organic electroluminescent device

An organic electroluminescent device of which emission life may be improved. The organic electroluminescent device includes an anode, an emission layer, and an anode-side hole transport layer provided between the anode and the emission layer and including an anode-side hole transport material. ... Incept Llc

05/17/18 / #20180134934

Protein-containing adhesives, and manufacture and use thereof

The invention provides protein adhesives and methods of making and using such adhesives. The protein adhesives contain ground plant meal or an isolated polypeptide composition obtained from plant biomass.. ... Incept Llc

05/17/18 / #20180134859

Synthetic high polymer film having surface provided with antiseptic property

A synthetic polymer film (34a), (34b) having a surface which has a plurality of raised portions (34ap), (34bp), wherein a two-dimensional size of the plurality of raised portions (34ap), (34bp) is in a range of more than 20 nm and less than 500 nm when viewed in a normal direction of the synthetic polymer film (34a), (34b), the surface having a microbicidal effect, and a zeta potential at the surface is not more than -46.3 mv.. . ... Incept Llc

05/17/18 / #20180134813

Process for the preparation of polysaccharides

The present invention relates to a process for the preparation of a polysaccharide composed of d-xylose units of formula (iii) linked together via beta 1,4 glycosidic bonds wherein r1 is hydrogen or acetyl, r2 is hydrogen, acetyl or a 4-o-methyl glucuronic acid unit, wherein, when r2 is a 4-o-methyl glucuronic acid unit, the r1 group on the same saccharide unit is defined as g, wherein g is hydrogen or acetyl, and wherein the sugar unit at the reducing end of sun such polysaccharide is xylose, lyxose or xylulose, said process comprising the following steps: selective deacetylation of xylan extracted from beech wood; and isomerization of the selectively deacetylated xylan achieved in step or the following steps: isomerization of xylan extracted from beech wood; and selective deacetylation of isomerized xylan achieved in step. The process is useful for the preparation of pentosan polysulfate or pharmaceutically acceptable salts thereof for pharmaceutical use.. ... Incept Llc

05/17/18 / #20180134810

Uranium-chelating peptides and uses thereof

The invention concerns uranium-chelating peptides as well as their uses for decontaminating soils and water, and for detecting and treating people contaminated by uranium. Said peptides have a helix-loop-helix type structure comprising the sequence of a calmodulin loop including at least one mutation of neutral residues selected from the group consisting of s, t, c, h, y, n and q, of one, two or three residues of at least one of the four calmodulin calcium binding sites: site i: residues selected among d20, d22 and d24 residues; site ii: residues selected among d56, d58 and n60 residues; site iii: residues selected among d93, d95 and n97 residues; site iv: residues selected among d129, d131 and d133 residues; said positions being indicated with reference to the human calmodulin sequence.. ... Incept Llc

05/17/18 / #20180134809

Antibody dual display dual compositions and methods of use thereof

Provided herein are display systems for simultaneously displaying two different ligand binding polypeptides at the surface of a phage. Also provided are kits, methods of using such display systems and methods of discovering novel bispecific antibodies.. ... Incept Llc

05/17/18 / #20180134804

Monoclonal antigen-binding proteins to intracellular oncogene products

Antigen binding proteins specific for an hla-a2 restricted ras peptide are disclosed. The antigen binding proteins encompass antibodies in a variety of forms, including full-length antibodies, substantially intact antibodies, fab fragments, f(ab′)2 fragments, and single chain fv fragments. ... Incept Llc

05/17/18 / #20180134802

Compositions comprising chimeric antigen receptors, t cells comprising the same, and methods of using the same

Provided are isolated nucleic acid molecules encoding chimeric antigen receptors (cars) that bind to tumor antigens. Also provided are isolated polypeptides and cars encoded by the isolated nucleic acid molecules, vectors that include the isolated nucleic acid molecules, cells that include the isolated nucleic acid molecules, methods of making the same, and methods for using the same to generate a persisting population of genetically engineered t cells in a subject, expanding a population of genetically engineered t cells in a subject, modulating the amount of cytokine secreted by a t cell, reducing the amount of activation-induced calcium influx into a t cell, providing an anti-tumor immunity to a subject, treating a mammal having a muc1-associated disease or disorder, stimulating a t cell-mediated immune response to a target cell population or tissue in a subject, and imaging a muc1-associated tumor.. ... Incept Llc

05/17/18 / #20180134799

Antibodies, pharmaceutical compositions and uses thereof

The present invention provides antibodies or the antigen-binding portion thereof, that bind to one or more carbohydrate antigens. Also disclosed herein are pharmaceutical pharmaceutical compositions and methods for the inhibition of cancer cells in a subject in need thereof. ... Incept Llc

05/17/18 / #20180134797

Anti-transferrin receptor antibodies and methods of use

The present invention relates to anti-trans-ferrin receptor antibodies and methods of their use.. . ... Incept Llc

05/17/18 / #20180134796

Il13ra2 binding agents and use thereof in cancer treatment

Provided are specific binding molecules, or fragments thereof, that bind to an epitope of il13rα2, a receptor polypeptide preferentially found on the surface of cancer cells rather than healthy cells. Exemplary specific binding molecules are bispecific binding molecules that comprise a fragment of an il13rα2 binding molecule and a peptide providing a second function providing a signaling function of the signaling domain of a t cell signaling protein, a peptide modulator of t cell activation, or an enzymatic component of a labeling system. ... Incept Llc

05/17/18 / #20180134795

Cd123 specific multi-chain chimeric antigen receptor

The present invention relates to a new generation of chimeric antigen receptors (car) referred to as multi-chain cars, which are made specific to the antigen cd123. Such cars aim to redirect immune cell specificity and reactivity toward malignant cells expressing the tumor antigen cd123. ... Incept Llc

05/17/18 / #20180134790

Antibodies reactive with b7-h3 and uses thereof

The present invention relates to antibodies that are immunoreactive to the mammalian, and more particularly, the human b7-h3 receptor and to uses thereof, particularly in the treatment of cancer and inflammation. The invention thus particularly concerns humanized b7-h3-reactive antibodies that are capable of mediating, and more preferably enhancing the activation of the immune system against cancer cells that are associated with a variety of human cancers.. ... Incept Llc

05/17/18 / #20180134789

Inducible binding proteins and methods of use

Provided herein are conditionally activated polypeptide constructs comprising a protease-activated domain binding to cd3, at least one half-life extension domain, and two or more domains binding to one or more target antigens. Also provided are pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such polypeptide constructs. ... Incept Llc

05/17/18 / #20180134788

Methods and pharmaceutical compositions (ntsr1 inhibitors) for the treatment of hepatocellular carcinomas

The present disclosure relates to methods and pharmaceutical compositions for the treatment of hepatocellular carcinomas (hcc in abbreviation, the term “hepatocellular carcinoma” has its general meaning in the art and refers to the cancer developed in hepatocytes see page 2 lines 24-30 of the present application) comprising administering to the subject a therapeutically effective amount of an inhibitor of ntsr1 (neurotensin receptor 1) activation or expression. The examples show the expression of ntsr1 in hcc cell lines and the role of the nts/ntsr1 complex in these cell lines, thereby showing the role of the complex in tumour progression.. ... Incept Llc

05/17/18 / #20180134767

Identification of antibodies specific for lyssaviruses and methods of their use

Described herein is a method of identifying a monoclonal antibody (or antigen-binding fragment thereof) that specifically binds a plurality of lyssaviruses for use in post-exposure rabies prophylaxis or in the treatment of clinical rabies. The method includes using a naive antibody phage display library to screen for phage clones that bind whole recombinant rabies virus or cells expressing glycoprotein from multiple lyssaviruses (such as rabv, mokv and wcbv) and/or specifically bind recombinant glycoprotein from different lyssaviruses.. ... Incept Llc

05/17/18 / #20180134766

Immunomodulatory fusion proteins

Provided is a fusion protein, e.g., a cytokine receptor fusion protein, e.g., a tgfβ trap, with a novel linker sequence to permit the fusion protein to functionally optimally, e.g., to permit a cytokine receptor portion of a cytokine receptor fusion protein to bind optimally to its target cytokine. The fusion proteins, or expression vectors encoding for the fusion proteins, e.g., oncolytic adenoviral expression vectors, can be used to treat cell proliferative diseases and disorders, including certain forms of cancer and inflammatory disorders.. ... Incept Llc

05/17/18 / #20180134765

Insertable variable fragments of antibodies and modified alpha1-alpha2 domains of nkg2d ligands, and non-natural nkg2d ligands that bind non-natural nkg2d receptors

This application relates generally to the production of polypeptides having specific antigen-binding properties of fv domains, for example, insertable variable fragments of antibodies, and modified α1-α2 domains of nkg2d ligands.. . ... Incept Llc








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