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Institute For Basic Science patents


Recent patent applications related to Institute For Basic Science. Institute For Basic Science is listed as an Agent/Assignee. Note: Institute For Basic Science may have other listings under different names/spellings. We're not affiliated with Institute For Basic Science, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "I" | Institute For Basic Science-related inventors


Endonuclease targeting blood coagulation factor viii gene and composition for treating hemophilia comprising same

The present invention provides a method for inducing an inversion of normal blood coagulation factor VIII (F8) gene, a method for correcting an inversion of blood coagulation factor VIII gene in which the inversion has occurred, and a Hemophilia A patient-derived induced pluripotent stem cell in which the inversion is... Institute For Basic Science

Pharmaceutical composition for prevention and treatment of mental disease with enhanced nmdar function

The present invention relates to a pharmaceutical composition for improving a sociability behavior in a patient having a mental disease with an enhanced NMDAR function.... Institute For Basic Science

Genome editing with split cas9 expressed from two vectors

The present invention relates to a method for regulating gene expression, comprising introducing into a cell each of a recombinant vector which expresses a first domain comprising N-terminus of a Cas9 protein, and a recombinant vector which expresses a second domain comprising C-terminus of a Cas9 protein, a composition comprising... Institute For Basic Science

Immune-compatible cells created by nuclease-mediated editing of genes encoding hla

The present invention relates to a method for producing immune-compatible cells or a cell population which comprises a step of editing one or two alleles of one or more immune-compatible antigen genes by gene deletion or modification in an isolated cell comprising at least one of the immune-compatible antigen genes... Institute For Basic Science

Polymer capsule having loaded thereon transition metal particles having excellent water dispersibility and stability, and preparing same

Provided are a polymer capsule loaded with transition metal particles having excellent water dispersibility and stability, and a method for preparing the same. Specifically, the polymer capsule loaded with transition metal particles according to the present invention includes a surface-modified polymer capsule surface-modified to thereby have a positive zeta potential... Institute For Basic Science

Cell sheet manufacturing device and manufacturing method therefor

The present invention relates to a cell sheet manufacturing device and a manufacturing method therefor. More specifically, the present invention relates to a cell sheet manufacturing device comprising a support layer made of silicon rubber, a patterned electrode formed adjacent to the support layer and a graphene layer formed adjacent... Institute For Basic Science

Synthesis of ultra-small ceria-zirconia nanoparticles and ceria-zirconia nano complex and its application as a therapeutic agent for sepsis

Disclosed is a ceria-zirconia nanoparticles comprising a core layer consisting of particles made of ceria-zirconia; and a surfactant layer formed by binding a surfactant on the surface of the core layer so as to easily react in vivo, and more particularly, to applying a ceria-zirconia nano complex to an application... Institute For Basic Science

Method for rgen rnp delivery using 5'-phosphate removed rna

Provided are a composition for ribonucleoprotein delivery, comprising a guide RNA free of 5′-terminal phosphates, and a method for ribonucleoprotein delivery, using the same.... Institute For Basic Science

Gene delivery system using polymer network

Provided is a gene delivery including a polymer network formed by binding phenylboronic acid, sugar, and a low-molecular weight branched polymer. The gene delivery may be stably maintained in vivo and efficiently deliver a gene specifically to cancer cells, such that the gene delivery system may be usefully used as... Institute For Basic Science

Quantum dot electronic device and quantum dot transfer printing method

A quantum dot electronic device comprises a first encapsulation layer, a first electrode disposed on the first encapsulation layer, a quantum dot pattern disposed on the first electrode, a second electrode disposed on the quantum dot pattern and a second encapsulation layer disposed on the second electrode. The quantum dot... Institute For Basic Science

Method of preparing silylative-reduced n-heterocyclic compound using organoboron catalyst

Provided is a method of preparing a silylative-reduced N-heterocyclic compound by reducing an N-heteroaromatic compound including a sp2 hybridized nitrogen atom while simultaneously introducing a silyl group into a beta-position with respect to a nitrogen atom of the N-heteroaromatic compound, using a silane compound, in the presence of an organoboron... Institute For Basic Science

Method for sensitive detection of target dna using target-specific nuclease

The present invention relates to a method for analyzing a genotype using a target-specific nuclease and, specifically, to a method for diagnosing cancer or analyzing a genotype by removing wild type DNA or particular genotype DNA using a target-specific nuclease or a variant thereof to amplify or concentrate only a... Institute For Basic Science

System for measuring displacement of accelerating tube in high-vacuum chamber by using micro-alignment telescope and method thereof

A system for measuring displacement of an accelerating tube by using a micro-alignment telescope, which includes a vacuum chamber; a hollow accelerating tube in the vacuum chamber; a sighting target attached to a surface of the accelerating tube while protruding from the surface of the accelerating tube; the micro-alignment telescope... Institute For Basic Science

Method of selectively releasing nitric oxide depending on change in ph using calcium phosphate

The method of selectively releasing nitric oxide according to the present invention may stably deliver nitric oxide to a desired site, and induce release of nitric oxide by a change in pH, thereby making it possible to improve a therapeutic effect while preventing a loss of nitric oxide.... Institute For Basic Science

A selecting a nuclease target sequence for gene knockout based on microhomology

The present invention relates to a method of selecting a nuclease target sequence for gene knockout based on microhomology.... Institute For Basic Science

Novel chiral metal complex and use thereof for analyzing chirality of charged compound by 1h nmr spectroscopy

Provided are novel ligand, a chiral metal complex including the same, and a use of the chiral metal complex for analyzing the chirality of a charged compound by 1H NMR spectroscopy. The chiral metal complex of the present invention may be used as the chiral solvating agent to conveniently analyze... Institute For Basic Science

Polymer capsule having loaded thereon transition metal particles having excellent water dispersibility and stability, and preparing same

Provided are a polymer capsule loaded with transition metal particles having excellent water dispersibility and stability, and a method for preparing the same. Specifically, the polymer capsule loaded with transition metal particles according to the present invention includes a surface-modified polymer capsule surface-modified to thereby have a positive zeta potential... Institute For Basic Science

Nanowire for anode material of lithium ion cell and preparing the same

The disclosure describes a nanowire for an anode material of a lithium ion cell and a method of preparing the same. The nanowire includes silicon (Si) and germanium (Ge). The nanowire has a content of the silicon (Si) higher than a content of the germanium (Ge) at a surface thereof,... Institute For Basic Science








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