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Institute For Research In Biomedicine
Institute For Research In Biomedicine irb
Institute For Research In Biomedicine_20100128

Institute For Research In Biomedicine patents


Recent patent applications related to Institute For Research In Biomedicine. Institute For Research In Biomedicine is listed as an Agent/Assignee. Note: Institute For Research In Biomedicine may have other listings under different names/spellings. We're not affiliated with Institute For Research In Biomedicine, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "I" | Institute For Research In Biomedicine-related inventors


Human cytomegalovirus neutralizing antibodies and use thereof

The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or a combination of two or more, hCMV gene UL products. The invention also relates to immortalized B cells that produce, and to epitopes... Institute For Research In Biomedicine

Recombinant metapneumovirus f proteins and their use

Metapneumovirus (MPV) F proteins stabilized in a prefusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the MPV F proteins and/or nucleic acid molecules can be used to generate an immune response to MPV in a subject.... Institute For Research In Biomedicine

Human cytomegalovirus neutralizing antibodies and use thereof

The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or a combination of two or more, hCMV gene UL products. The invention also relates to immortalized B cells that produce, and to epitopes... Institute For Research In Biomedicine

Neutralizing anti-influenza a virus antibodies and uses thereof

The invention relates to antibodies, and antigen binding fragments thereof, that specifically bind to an epitope in the stem region of an influenza A hemagglutinin trimer and neutralize a group 1 subtype and a group 2 subtype of influenza A virus. The invention also relates to nucleic acids that encode,... Institute For Research In Biomedicine

Human cytomegalovirus neutralizing antibodies and use thereof

The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or a combination of two or more, hCMV gene UL products. The invention also relates to immortalized B cells that produce, and to epitopes... Institute For Research In Biomedicine

Human cytomegalovirus neutralizing antibodies and use thereof

The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or a combination of two or more, hCMV gene UL products. The invention also relates to immortalized B cells that produce, and to epitopes... Institute For Research In Biomedicine

Human cytomegalovirus vaccine compositions and producing the same

The present invention provides for a vector and a gene expression system for producing a soluble pentameric protein complex comprising the HCMV glycoproteins UL128, UL130, UL131, gH and gL or sequence variants thereof, as well as vaccine compositions comprising the same. The present invention further provides for a vaccine composition... Institute For Research In Biomedicine

Human cytomegalovirus neutralizing antibodies and use thereof

The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or a combination of two or more, hCMV gene UL products. The invention also relates to immortalized B cells that produce, and to epitopes... Institute For Research In Biomedicine

Genetically modified non-human animals and methods of use thereof

Genetically modified non-human animals are provided that may be used to model human hematopoietic cell development, function, or disease. The genetically modified non-human animals comprise a nucleic acid encoding human IL-6 operably linked to an IL-6 promoter. In some instances, the genetically modified non-human animal expressing human IL-6 also expresses... Institute For Research In Biomedicine

Genetically modified non-human animals and methods of use thereof

The invention relates generally to genetically modified non-human animals expressing human polypeptides and their methods of use.... Institute For Research In Biomedicine

Humanized m-csf mice

Genetically modified mice comprising a nucleic acid sequence encoding a human M-CSF protein are provided. Also provided are genetically modified mice comprising a nucleic acid sequence encoding a human M-CSF protein that have been engrafted with human cells such as human hematopoietic cells, and methods for making such engrafted mice.... Institute For Research In Biomedicine

Genetically modified mice and engraftment

A mouse with a humanization of the mIL-3 gene and the mGM-CSF gene, a knockout of a mRAG gene, and a knockout of a mll2rg subunit gene; and optionally a humanization of the TPO gene is described. A RAG/ll2rg KO/hTPO knock-in mouse is described. A mouse engrafted with human hematopoietic... Institute For Research In Biomedicine








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