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Intarcia Therapeutics Inc patents


Recent patent applications related to Intarcia Therapeutics Inc. Intarcia Therapeutics Inc is listed as an Agent/Assignee. Note: Intarcia Therapeutics Inc may have other listings under different names/spellings. We're not affiliated with Intarcia Therapeutics Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "I" | Intarcia Therapeutics Inc-related inventors


Glucagon-receptor selective polypeptides and methods of use thereof

This invention relates to isolated polypeptides that are glucagon-receptor selective analogs and peptide derivatives thereof. These analogs are selective for human glucagon receptor with improved solubility, thermal stability, and physicochemical properties as compared to native endogenous glucagon. This invention also relates to methods of using such polypeptides in a variety... Intarcia Therapeutics Inc

Osmotic delivery device comprising an insulinotropic peptide and uses thereof

A suspension formulation of an insulinotropic peptide (e.g., glucagon-like peptide-1 (GLP-1) or exenatide) is described. The suspension formulation comprises (i) a non-aqueous, single-phase vehicle, comprising one or more polymer and one or more one solvent, wherein the vehicle exhibits viscous fluid characteristics, and (ii) a particle formulation comprising the insulinotropic... Intarcia Therapeutics Inc

Solvent/polymer solutions as suspension vehicles

A nonaqueous, single-phase vehicle that is capable of suspending an active agent. The nonaqueous, single-phase vehicle includes at least one solvent and at least one polymer and is formulated to exhibit phase separation upon contact with an aqueous environment. The at least one solvent may be selected from the group... Intarcia Therapeutics Inc

Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles

This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The... Intarcia Therapeutics Inc

Methods of manufacturing viscous liquid pharmaceutical formulations

A liquid composition in an osmotic drug delivery system and a dosage form in an osmotic drug delivery system is disclosed comprising an amphiphilic molecule, a non-aqueous liquid solvent, and a pharmaceutically active agent.... Intarcia Therapeutics Inc

Compositions, devices and methods of use thereof for the treatment of cancers

The use of GLP-1 receptor agonists, such as glucagon-like peptide-1 (GLP-1) or exenatide, for the treatment of cancer is described. The GLP-1 receptor agonists are typically delivered using an implanted osmotic delivery device that provides for continuous delivery of the GLP-1 receptor agonist for at least one month. Additional beneficial... Intarcia Therapeutics Inc

Two-piece, internal-channel osmotic delivery system flow modulator

An osmotic delivery system flow modulator includes an outer shell constructed and arranged for positioning in an opening, an inner core inserted in the outer shell, and a fluid channel having a spiral shape defined between the outer shell and the inner core. The fluid channel is adapted for delivery... Intarcia Therapeutics Inc

Highly concentrated drug particles, formulations, suspensions and uses thereof

Highly concentrated drug particle formulations are described, wherein the drug comprises between about 25 wt % and 80 wt % of the particle formulation. The particle formulations of the present invention comprise, for example, macromolecules, such as proteins and/or small molecules (such as steroid hormones). The particle formulation typically further... Intarcia Therapeutics Inc

Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles

This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The... Intarcia Therapeutics Inc

Devices, formulations, and methods for delivery of multiple beneficial agents

The present invention relates to osmotic delivery devices, formulations, and methods for delivery of two or more beneficial agents. In one aspect, the present invention provides osmotic delivery devices useful for substantially concurrent administration of two or more beneficial agents. In another aspect, the present invention provides beneficial agent formulations... Intarcia Therapeutics Inc

Osmotic delivery device comprising an insulinotropic peptide and uses thereof

A suspension formulation of an insulinotropic peptide (e.g., glucagon-like peptide-1 (GLP-1) or exenatide) is described. The suspension formulation comprises (i) a non-aqueous, single-phase vehicle, comprising one or more polymer and one or more one solvent, wherein the vehicle exhibits viscous fluid characteristics, and (ii) a particle formulation comprising the insulinotropic... Intarcia Therapeutics Inc

Solvent/polymer solutions as suspension vehicles

A nonaqueous, single-phase vehicle that is capable of suspending an active agent. The nonaqueous, single-phase vehicle includes at least one solvent and at least one polymer and is formulated to exhibit phase separation upon contact with an aqueous environment. The at least one solvent may be selected from the group... Intarcia Therapeutics Inc








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