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Intercept Pharmaceuticals Inc
Intercept Pharmaceuticals Inc_20100128

Intercept Pharmaceuticals Inc patents


Recent patent applications related to Intercept Pharmaceuticals Inc. Intercept Pharmaceuticals Inc is listed as an Agent/Assignee. Note: Intercept Pharmaceuticals Inc may have other listings under different names/spellings. We're not affiliated with Intercept Pharmaceuticals Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "I" | Intercept Pharmaceuticals Inc-related inventors


Methods for modulating bone density

The present invention relates to methods of treating, reducing the risk of, preventing, or alleviating a symptom of a disease or condition associated with changes in bone density, osteoporosis, or an osteopenic disease, or inducing osteogenesis or bone growth, or slowing, preventing, or reversing the reduction in bone density in... Intercept Pharmaceuticals Inc

Tgr5 modulators and methods of use thereof

or a salt, solvate, hydrate, or prodrug thereof. The compounds of Formula A are TGR5 modulators useful for the treatment of various diseases, including metabolic disease, inflammatory disease, liver disease, autoimmune disease, cardiac disease, kidney disease, cancer, and gastrointestinal disease.... Intercept Pharmaceuticals Inc

Pharmaceutical compositions for combination therapy

The present invention relates to a pharmaceutical composition comprising a combination of an FXR agonist and at least one lipid lowering agent (e.g., PPAR-alpha agonist, PPAR-delta agonist, PPAR-alpha and delta dual agonist, and/or statin). Also disclosed is use of the combination for the treatment or prevention of a FXR mediated... Intercept Pharmaceuticals Inc

Steroids as agonists for fxr

wherein R is ethyl, propyl or allyl, and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. The compounds of formula (I) are useful as FXR agonists.... Intercept Pharmaceuticals Inc

Methods of treating cancer

The present invention relates to methods of treating or preventing cancer in a subject in need thereof comprising administering a therapeutically effective amount of a compound of the invention.... Intercept Pharmaceuticals Inc

3-desoxy derivative and pharmaceutical compositions thereof

or a pharmaceutically acceptable salt or amino acid conjugate thereof. The present invention relates to an FXR activator and to methods of making and using said compound.... Intercept Pharmaceuticals Inc

Preparation and uses of obeticholic acid

or a pharmaceutically acceptable salt, solvate or amino acid conjugate thereof. Obeticholic acid is useful for the treatment or prevention of a FXR mediated disease or condition, cardiovascular disease or cholestatic liver disease, and for reducing HDL cholesterol, for lowering triglycerides in a mammal, or for inhibition of fibrosis. The... Intercept Pharmaceuticals Inc

Farnesoid x receptor modulators

or a pharmaceutically acceptable salt, solvate, or amino acid conjugate thereof, wherein R1, R2, R3, R4, R5, and R6 are as described herein. The present invention relates generally to selective FXR agonists and to methods of making and using them.... Intercept Pharmaceuticals Inc

Treatment of fibrosis using fxr ligands

The present invention relates to a method for inhibiting fibrosis that occurs in an organ where the farnesoid X receptor (FXR) is expressed. This method involves the step of administering a high potency, activating ligand of FXR in an effective amount to a patient who is not suffering from a... Intercept Pharmaceuticals Inc

Farnesoid x receptor modulators

or a pharmaceutically acceptable salt, solvate, or amino acid conjugate thereof, wherein R1-R10, m, n, p, and are as described herein. The present invention relates generally to FXR modulators and to methods of making and using said compounds.... Intercept Pharmaceuticals Inc

Compositions of obeticholic acid and methods of use

The disclosure relates to obeticholic acid formulations with improved stability, dissolution, and/or solubility, methods of preparing the same for use and methods of treating various diseases and conditions.... Intercept Pharmaceuticals Inc








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