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Isis Pharmaceuticals Inc
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Isis Pharmaceuticals Inc patents

Recent patent applications related to Isis Pharmaceuticals Inc. Isis Pharmaceuticals Inc is listed as an Agent/Assignee. Note: Isis Pharmaceuticals Inc may have other listings under different names/spellings. We're not affiliated with Isis Pharmaceuticals Inc, we're just tracking patents.

ARCHIVE: New 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "I" | Isis Pharmaceuticals Inc-related inventors




Date Isis Pharmaceuticals Inc patents (updated weekly) - BOOKMARK this page
12/01/16Modulation of signal transducer and activator of transcription 3 (stat3) expression
06/09/16Methods and compounds useful in conditions related to repeat expansion
06/09/16Methods of predicting toxicity
06/02/16Compounds and methods for modulating apolipoprotein c-iii expression for improving a diabetic profile
05/26/16Compositions for modulating tau expression
05/19/16Antisense compounds and uses thereof
05/05/16Compositions and methods for modulation of target nucleic acids
03/31/16Compositions and methods for modulating apolipoprotein c-iii expression
03/31/16Compositions and methods for modulating apolipoprotein (a) expression
03/31/16Antisense compounds and uses thereof
03/17/16Compositions and methods for modulation nucleic acids through nonsense mediated decay
03/17/16Compositions and methods for modulation nucleic acids through nonsense mediated decay
03/17/16Compositions and methods for modulating hbv expression
03/17/16Phosphorous-linked oligomeric compounds and their use in gene modulation
03/17/16Compositions and methods
03/10/16Modulation of androgen receptor expression
03/10/16Modulation of dystrophia myotonica-protein kinase (dmpk) expression
03/03/16Modulation of apolipoprotein ciii (apociii) expression
03/03/16Modulation of angiopoietin-like 3 expression
02/25/16Compositions and their uses directed to huntingtin
02/25/16Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
02/18/165' modified nucleosides and oligomeric compounds prepared therefrom
02/18/16Modulation of hepatitis b virus (hbv) expression
02/04/16Compositions and methods for modulating tau expression
01/28/16Methods for monitoring c9orf72 expression
01/21/16Conjugated antisense compounds and their use
01/21/16Chimeric oligomeric compounds and their use in gene modulation
01/21/16Double strand compositions comprising differentially modified strands for use in gene modulation
01/14/16Oligomeric compounds and excipients
01/07/16Cancer treatment
01/07/16Cancer treatment
01/07/16Antisense oligonucleotide compositions
01/07/16Compositions and methods for modulation of smn2 splicing in a subject
01/07/16Compositions and methods for modulation of smn2 splicing in a subject
12/31/15Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations
12/31/15Antisense oligonucleotides directed against connective tissue growth factor and uses thereof
12/31/15Selective antisense compounds and uses thereof
12/24/152'-methoxy substituted oligomeric compounds and compositions for use in gene modulations
12/24/15Method of preparing oligomeric compounds using modified coupling protocols
12/10/15Compositions and methods for modulation of smn2 splicing
12/03/15Compounds and methods for modulating gene expression
11/26/15Methods and compositions for modulating apolipoprotein (a) expression
11/19/15Selective reduction of allelic variants
11/12/15Compounds and methods for improved cellular uptake of antisense compounds
11/12/15Oligomeric compounds and compositions for the use in modulation of micrornas
11/05/15Double strand compositions comprising differentially modified strands for use in gene modulation
11/05/15Compounds and methods for improving cellular uptake of oligomeric compounds
11/05/15Compositions and methods for modulating angiopoietin-like 3 expression
11/05/15Antisense modulation of ptp1b expression
10/29/15Compositions and their uses directed to huntingtin
10/22/15Modulation of renin-angiotensin system (ras) related diseases by angiotensinogen
10/22/15Modulation of renin-angiotensin system (ras) related diseases by angiotensinogen
10/22/15Competitive modulation of micrornas
10/15/15Antisense compounds targeting genes associated with fibronectin
10/15/15Modulation of cd40 expression
10/15/15Selective reduction of allelic variants
10/08/15Methods of treating kennedy's disease
10/01/15Methods for modulating tau expression for reducing seizure and modifying a neurodegenerative syndrome
10/01/15Selective antisense compounds and uses thereof
10/01/15Antisense compounds and uses thereof
09/24/15Oligomeric compounds comprising bicyclic nucleosides and uses thereof
09/24/15Methods for modulating c9orf72 expression
09/17/15Compositions for modulating c9orf72 expression
09/17/15Oligomeric compounds comprising tricyclic nucelosides and methods for their use
09/10/15Modulation of transthyretin expression
Patent Packs
08/06/15Method of preparing oligomeric compounds using modified capping protocols
07/09/15Modulation of ube3a-ats expression
07/09/15Bicyclic cyclohexose nucleic acid analogs
07/02/15Oligomeric compounds comprising bicyclic nucleotides and uses thereof
07/02/15Modulation of apolipoprotein (a) expression
07/02/15Modulation of transthyretin expression
07/02/15Antisense modulation of fibroblast growth factor receptor 4 expression
06/25/15Modulation of enhancer rna mediated gene expression
06/25/15Compositions and methods for modulating hbv expression
06/18/15Methods for treating hypercholesterolemia
06/18/15Oligomeric compounds and methods
06/18/15Antisense modulation of superoxide dismutase 1, soluble expression
06/11/15Modulation of huntingtin expression
06/11/15Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom
06/04/15Methods and compositions for modulating apolipoprotein (a) expression
Patent Packs
05/21/15Antisense modulation of gccr expression
05/21/15Oligomeric compounds comprising bicyclic nucleosides and having reduced toxicity
05/07/15Conjugated antisense compounds and their use
05/07/15Compositions and methods for modulating apolipoprotein c-iii expression
05/07/15Compositions and methods for modulating apolipoprotein (a) expression
05/07/155' and 2' bis-substituted nucleosides and oligomeric compounds prepared therefrom
04/23/15Tricyclic nucleic acid analogs
04/16/15Antisense compounds targeting genes associated with fibronectin
04/09/15Antisense modulation of gcgr expression
03/26/15Methods and compositions for modulating alpha-1-antitrypsin expression
02/26/15Compounds and methods for modulating expression apob
02/19/15Selective antisense compounds and uses thereof
01/29/15Methods and compositions for modulating factor vii expression
01/22/15Compositions and methods for modulation of ikbkap splicing
01/15/15Oligomer-conjugate complexes and their use
01/08/15Compositions and methods for optimizing cleavage of rna by rnase h
12/25/14Modulation of rna by repeat targeting
12/18/14Methods for modulating metastasis-associated-in-lung-adenocarcinoma-transcript-1 (malat-1) expression
12/18/14Methods for modulating metastasis-associated-in-lung-adenocarcinoma-transcript-1 (malat-1) expression
12/04/14Compositions and methods for treatment of spinal muscular atrophy
12/04/14Modulation of hepatitis b virus (hbv) expression
12/04/14Chimeric oligomeric compounds comprising alternating regions of northern and southern conformational geometry
11/20/14Conjugated antisense compounds and their use
10/30/14Selective antisense compounds and uses thereof
10/23/14Tetrahydropyran nucleic acid analogs
10/23/14Methods and compounds useful in conditions related to repeat expansion
10/16/14Gapped oligomeric compounds comprising 5'-modified deoxyribonucleosides in the gap and uses thereof
10/16/14Compositions and methods for modulation of lmna expression
10/16/14Modulation of tmprss6 expression
10/09/14Linkage modified gapped oligomeric compounds and uses thereof
Social Network Patent Pack
09/25/14Compounds and methods for modulating protein expression
09/18/14Antisense compounds and methods of use thereof
09/11/14Modulation of transthyretin expression
08/21/14Antisense modulation of ptp1b expression
08/14/14Methods for modulating factor 12 expression
07/31/14Methods for modulating kallikrein (klkb1) expression
07/24/14Methods for modulating kallikrein (klkb1) expression
07/24/14Modulation of apolipoprotein (a) expression
07/10/14Modulation of angiopoietin-like 3 expression
07/10/14Methods for treating hypercholesterolemia
Patent Packs
05/08/14Modulation of apolipoprotein ciii (apociii) expression
04/24/14Antisense compounds targeting genes associated with usher syndrome
04/17/14Modulation of androgen receptor expression
04/17/14Modulation of hepatitis b virus (hbv) expression
04/17/14Oligomeric compounds comprising bicyclic nucleotides and uses thereof
03/13/14Cyclohexenyl nucleic acids analogs
01/09/14Compounds and methods for modulating target nuclear and sub-nuclear nucleic acid molecules in cells and animals
01/02/14Modulation of alpha synuclein expression
12/12/13Methods for modulating factor 12 expression
12/12/13Antisense modulation of kinesin-like 1 expression
12/05/135'-end derivatives
11/28/13Modulation of apolipoprotein c-iii expression
11/07/13Antidotes to antisense compounds
10/31/13Compounds and methods for modulating interaction between proteins and target nucleic acids
10/17/13Compositions and methods for non-parenteral delivery of oligonucleotides
10/03/13Conformationally restricted dinucleotide monomers and oligonucleotides
09/26/13Methods of determining potency of chemically-synthesized oligonucleotides
09/12/13Modulation of dystrophia myotonica-protein kinase (dmpk) expression
08/29/13Modulation of nuclear-retained rna
08/22/13Modulation of phosphoenolpyruvate carboxykinase-mitchondrial (pepck-m) expression
08/15/13Tetrahydropyran nucleic acid analogs
08/01/13Oligomeric compounds comprising tricyclic nucelosides and methods for their use
07/25/13Compositions and their uses directed to huntingtin
07/25/13Modulation of factor 11 expression
07/11/13Modulation of eif4e expression
06/27/13Compounds and methods for improving cellular uptake of oligomeric compounds
06/27/13Compounds and methods for modulating expression of gccr
06/20/13Lipid formulated single stranded rna
06/13/13Antisense modulation of gccr expression
06/13/13Bicyclic nucleosides and oligomeric compounds prepared therefrom
Patent Packs
06/06/13Modulation of glucocorticoid receptor expression
06/06/13Antibacterial 4,6-substituted 6', 6'' and 1 modified aminoglycoside analogs
05/23/13Substituted 2'-amino and 2'-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom
05/16/13Modulation of diacylglycerol acyltransferase 2 expression
05/09/13Antisense modulation of gcgr expression
05/09/135' modified nucleosides and oligomeric compounds prepared therefrom
05/02/13Modified 5' diphosphate nucleosides and oligomeric compounds prepared therefrom
05/02/13Compositions and methods for modulation of smn2 splicing
05/02/13Compositions and their uses directed to aceytl-coa carboxylases
04/04/13Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom
03/28/13Antisense oligonucleotide modulation of raf gene expression
03/07/13Modulation of glucose-6-phosphatase translocase expression
03/07/13Methods and compositions useful in treatment of diseases or conditions related to repeat expansion
02/28/13Modulation of cetp expression
02/21/13Selective reduction of allelic variants
02/21/13Selective reduction of allelic variants
02/14/13Base modified bicyclic nucleosides and oligomeric compounds prepared therefrom
02/14/135'-substituted bicyclic nucleosides and oligomeric compounds prepared therefrom
02/07/13Double strand compositions comprising differentially modified strands for use in gene modulation
02/07/13Compositions and methods for modulation of lmna expression
Social Network Patent Pack
01/24/13Modulation of angiopoietin-like 3 expression
01/03/13Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
12/13/12Modulation of apolipoprotein(a) expression
12/13/12Compositions and their uses directed to il-4r alpha
12/06/12Compositions and methods for topical delivery of oligonucleotides
11/22/12Proinflammatory nucleic acids
11/22/12Modulation of glucagon receptor expression
11/08/12Modulation of eif4e expression
10/25/12Compositions and methods for treatment of pouchitis
10/25/12Modulation of ttc39 expression to increase hdl
09/13/12Modulation of diacylglycerol acyltransferase 1 expression
08/23/12Compositions and methods for the modulation of jnk proteins
08/23/12Modulation of factor 7 expression
08/23/12Methods for slowing familial als disease progression
08/16/12Compounds and methods for modulating expression of gcgr
08/09/12Antisense oligonucleotide modulation of stat3 expression
08/02/12Modulation of sglt-2 expression
07/19/12Antisense inhibition via rnase h-independent reduction in mrna
07/05/12Bicyclic cyclohexose nucleic acid analogs
06/28/12Modulation of exportin 5 expression
Social Network Patent Pack
06/28/12Supports for oligomer synthesis
06/14/12Modulation of transthyretin expression
06/14/12Antisense oligonucleotide modulation of raf gene expression
06/14/12Modulation of eif4e-bp2
05/17/12Method for rapid detection and identification of bioagents in epidemiological and forensic investigations
05/17/12Secondary structure defining database and methods for determining identity and geographic origin of an unknown bioagent thereby
05/10/12Oligomeric compounds and compositions for the use in modulation of micrornas
05/10/12Compositions and their uses directed to hepcidin
05/10/12Modulation of stat 6 expression
05/10/12Organic compositions to treat beta-enac-related diseases
04/12/12Methods of modulating an immune response to a viral infection
03/29/12Methods of determining potency of chemically-synthesized oligonucleotides
03/29/12Antisense modulation of ptp1b expression
03/29/12Methods for treating hypercholesterolemia
03/29/12Antisense modulation of c-reactive protein expression
03/22/12Tetrahydropyran nucleic acid analogs
03/08/12Methods of using oligomeric compounds comprising 2'-substituted nucleosides
02/02/12Compositions and their uses directed to diacylglycerol acyltransferase 1
01/26/12Antisense modulation of cholesteryl ester transfer protein expression
01/12/125'-modified bicyclic nucleic acid analogs
12/22/11Oligomeric compounds and methods
12/15/11Compositions and their uses directed to huntingtin
12/08/11Combination therapy for the treatment of cancer
11/17/11Combination therapy for the treatment of cancer
11/03/11Modulation of prion expression
11/03/115' and 2' bis-substituted nucleosides and oligomeric compounds prepared therefrom
10/20/11Pulsatile release compositions and methods for enhanced intestinal drug absorption
10/06/11Antibacterial 4,6-substituted 6', 6" and 1 modified aminoglycoside analogs
09/29/11Modulation of transthyretin expression for the treatment of cns related disorders
09/22/11Modulation of c-reactive protein expression
Social Network Patent Pack
09/01/11Compositions and methods for topical delivery of oligonucleotides
09/01/11Oligonucleotidic sequences able to silence the expression of the cyclin d1-trop2 chimera and uses thereof in medical field
09/01/11Antisense modulation of stearoyl-coa desaturase expression
08/25/11Enhanced antisense oligonucleotides
08/04/11Modulation of hif1(alpha) and hif2(alpha) expression
07/14/11Conjugates for use in hepatocyte free uptake assays
07/07/11Modulation of glucose-6-phosphatase translocase expression
06/30/11Modulation of cd40 expression
06/23/11Modulation of smrt expression
06/09/11Compositions and their uses directed to aceytl-coa carboxylases
06/02/11Oligomeric compounds having at least one neutrally linked terminal bicyclic nucleosides
05/26/11Compounds and methods for modulating protein expression
05/26/11Methods for modulating expression of rbp4
05/19/11Antisense modulation of c-reactive protein expression
05/12/11Oligomeric compounds comprising bicyclic nucleosides and having reduced toxicity
05/12/11Compositions and their uses directed to ptpru
05/05/11Compositions and their uses directed to gemin genes
04/28/11Antisense modulation of bcl2-associated x protein expression
04/21/11Modulation of growth hormone receptor expression and insulin-like growth factor expression
04/21/11Modification of myd88 splicing using modified oligonucleotides
03/31/11Bicyclic cyclohexitol nucleic acid analogs
03/17/11Compounds and methods for modulating expression of sglt2
03/10/11Modulation of factor 9 expression
03/10/11Modulation of apolipoprotein c-iii expression
03/03/11Antisense oligonucleotide modulation of stat3 expression
02/24/11Double strand compositions comprising differentially modified strands for use in gene modulation
02/17/11Chimeric oligomeric compounds for modulation of splicing
02/17/11Modulation of apolipoprotein (a) expression
02/17/11Antisense modulation of hydroxysteroid 11-beta dehydrogenase 1 expression







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