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Jiangsu Hengrui Medicine Co Ltd patents


Recent patent applications related to Jiangsu Hengrui Medicine Co Ltd. Jiangsu Hengrui Medicine Co Ltd is listed as an Agent/Assignee. Note: Jiangsu Hengrui Medicine Co Ltd may have other listings under different names/spellings. We're not affiliated with Jiangsu Hengrui Medicine Co Ltd, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "J" | Jiangsu Hengrui Medicine Co Ltd-related inventors


Anti-sclerostin antibody, antigen binding fragment and medical use thereof

Provided is a humanized antibody and chimeric antibody that specifically binds human sclerostin. The antibodies can be used for treating human bone metabolism related diseases such as osteoporosis (OP).... Jiangsu Hengrui Medicine Co Ltd

Pyridic ketone derivatives, preparing same, and pharmaceutical application thereof

Compounds for the preparation of pyridone derivatives are provided. In particular, compounds of formula (IA) are provided, wherein the variable groups are as defined in the specification. The compounds of formula (IA) can be used as intermediates in the preparation of pyridone derivatives useful as mitogen-activated protein kinase kinase (MEK)... Jiangsu Hengrui Medicine Co Ltd

Hydroxyethyl sulfonate of cyclin-dependent protein kinase inhibitor, crystalline form thereof and preparation method therefor

Provided are a hydroxyethyl sulfonate of a cyclin-dependent protein kinase inhibitor, a crystalline form thereof and a preparation method therefor. Specifically, 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperidin-4-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydroxyethyl sulfonate (compound of formula (I)), a crystal form I thereof and a preparation method therefor are provided. Crystal form I of the compound of formula (I) has... Jiangsu Hengrui Medicine Co Ltd

Pyridinecarboxamide derivatives, preparation method thereof and pharmaceutical uses thereof

Pyridinecarboxamide derivatives, preparation methods, and a pharmaceutical uses thereof are provided. In particular, pyridinecarboxamide derivatives represented by general formula (I), wherein the substituents of the formula (I) are defined in the specification are provided. Also provided are a preparation method for the pyridinecarboxamide derivatives of formula (I), a pharmaceutical composition... Jiangsu Hengrui Medicine Co Ltd

Crystalline form of jak kinase inhibitor bisulfate and a preparation method thereof

A crystal form of JAK kinase inhibitor bisulfate and a preparation method thereof are provided. In particular, a type II crystal of (3aR,5s,6aS)-N-(3-methoxyl-1,2,4-thiadiazole-5-yl)-5-(methyl(7H-pyrrolo[2,3-d]pyrimidine-4-yl)amino)hexahydrocyclopenta[c]pyrrole-2(1H)-formamide bisulfate and a preparation method thereof are described. The preparation method includes steps of crystallizing any solid crystal form or amorphous compound of formula (I) in a... Jiangsu Hengrui Medicine Co Ltd

L-proline complex of sodium-glucose cotransporter 2 inhibitor, monohydrate and crystal form thereof

Provided are an L-proline complex of a sodium-glucose cotransporter 2 inhibitor, and a monohydrate and a crystal of the L-proline complex. Specifically, provided are 1,6-dehydrated-1—C{4-chloro-3-[(3-fluoro-4-ethoxyphenyl)methyl]phenyl}-5—C-(hydroxymethyl)-β-L-idopyranose L-proline (a compound of formula (I)), a monohydrate and a type A crystal thereof, and a preparation method therefor. The obtained type A crystal of... Jiangsu Hengrui Medicine Co Ltd

Pregabalin sustained-release preparation

Disclosed is a pregabalin sustained-release preparation, wherein the sustained-release tablet contains a pharmaceutically active ingredient containing pregabalin or a salt or hydrate thereof, a gel framework material containing alginic acid, and a swellable material containing polyoxyethylene.... Jiangsu Hengrui Medicine Co Ltd

Liposome of irinotecan or irinotecan hydrochloride and preparation method thereof

A liposome of irinotecan or irinotecan hydrochloride and its preparation method are disclosed. The liposome contains irinotecan or irinotecan hydrochloride, neutral phospholipid and cholesterol, wherein the weight ratio of the cholesterol to the neutral phospholipid is 1:3 to 1:5. The liposome is prepared by an ion gradient method.... Jiangsu Hengrui Medicine Co Ltd

Methods of treating androgen receptor-mediated disorders with imidazoline derivatives

Methods for treating androgen receptor-mediated diseases, such as breast cancer, with imidazoline derivatives of formula (I) are provided:... Jiangsu Hengrui Medicine Co Ltd

Compounds for preparing pyrrole six-membered heteroaryl ring derivative

Intermediate compounds used in the preparation of pyrrole six-membered heteroaryl ring derivatives are disclosed. In particular, compounds of formula (IB) are disclosed. The compounds of formula (IB) are used in the synthesis of Janus kinase (JAK) inhibitors. Substituents in formula (IB) have the same definitions as in the description.... Jiangsu Hengrui Medicine Co Ltd

Amide derivatives and pharmaceutically acceptable salts thereof, preparation method thereof and medicinal application thereof

Amide derivatives and pharmaceutically acceptable salts thereof, preparation method thereof and medicinal application thereof are provided. Specifically, amide derivatives represented by general formula (I) are provided. The amide derivatives represented by general formula (I) can be used as a therapeutic agent, particularly as an inhibitor for microsomal prostaglandin E synthase-1... Jiangsu Hengrui Medicine Co Ltd

Il-15 heterodimeric protein and uses thereof

Provided is an IL-15 heterodimeric protein, such as an IL-15/IL-15Rα heterodimeric protein. The IL-15 heterodimeric protein contains protein (I) and protein (II). Protein (I) is recombinantly produced by combining IL-15 or a variant thereof with a first Fc variant, and protein (II) is a second Fc variant, or recombinantly produced... Jiangsu Hengrui Medicine Co Ltd

Ligand-cytotoxic drug conjugate, preparation method thereof, and uses thereof

Ligand-cytotoxic drug conjugates, pharmaceutical compositions, preparation methods, and pharmaceutical uses thereof are provided. More specifically, a ligand-cytotoxic drug conjugate of general formula Pc-(X-Y-D)n is provided. The ligand-cytotoxic drug conjugate can be used to treat cancer via receptor modulation.... Jiangsu Hengrui Medicine Co Ltd

Ligand-cytotoxic drug conjugate, preparation method thereof, and uses thereof

Ligand-cytotoxic drug conjugates, pharmaceutical compositions, preparation methods, and pharmaceutical uses thereof are provided. More specifically, a ligand-cytotoxic drug conjugate of general formula Pc-(X-Y-D)n is provided. The ligand-cytotoxic drug conjugate can be used to treat cancer via receptor modulation.... Jiangsu Hengrui Medicine Co Ltd








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