Kiromic Llc patents

Platform for the identification of tumor-associated cancer/testes antigens

Methods of identifying cancer/testes antigens (ctas) useful as cancer treatment targets are disclosed and claimed herein. The methods include identifying human sperm proteins to which patients diagnosed with solid or hematological malignancies have established a humoral immune response.. ... Kiromic Llc

Diagnosis and treatment of ciliated hepatic foregut cysts

This invention provides methods and compositions for diagnosis and treatment of ciliated hepatic foregut cysts (chfc). In particular, the methods utilize one or more cancer-testis (ct) antigens as a marker for chfc. ... Kiromic Llc

Human sperm fibrous sheath (fs) proteins: new target antigens for use in therapeutic cancer vaccines and diagnostic screening and methods of using same

Cancer vaccines were demonstrated to be promising strategies for cancer treatment; however these strategies are limited by the paucity of target antigens that provoke an effective immune response. The inventors of the present patent application propose that sperm fibrous sheet proteins constitute a new class of potential antigens for use in the development of effective, durable cancer vaccines. ... Kiromic Llc