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Lehigh University patents


Recent patent applications related to Lehigh University. Lehigh University is listed as an Agent/Assignee. Note: Lehigh University may have other listings under different names/spellings. We're not affiliated with Lehigh University, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "L" | Lehigh University-related inventors


Graded index single crystal active waveguide in glass

In one aspect the invention provides a graded refractive index single crystal waveguide having a glass block containing at least one crystal core, the crystal core having a central portion extending along an axis from a first end to a second end; an interface defining a peripheral boundary of the crystal core at a junction of the crystal core and an adjacent portion of the glass block, and a continuous, radially symmetric misorientation transverse to the central portion; wherein the misorientation has a misorientation angle that increases with increasing distance from the central portion towards the interface.. . ... Lehigh University

Scaffolds for uterine cell growth

A method for growing polarized endometrial cells, said method comprising: (a) disposing endometrial cells on a scaffold, said scaffold comprising a silica-based glass composition, characterized by multi-modal porosity, said scaffold being to define a top side and a bottom side; (b) providing nutrients to said top and bottom sides of said scaffold and an environment to grow polarized endometrial cells on said scaffold.. . ... Lehigh University

Ductile chord connectors for use in concrete rods in structures

Provided herein are connectors for use in assembling reinforced concrete structures, as well as methods of assembly using the connectors. In one embodiment, the connectors and methods provide for secure and easy connection to the butt end of any rebar rod, as well as attachment of an opposite end to another metal structure. ... Lehigh University

In-situ, self-adjusting stability control of methane-producing anaerobic biological reactors through novel use of ion exchange fibers

An anaerobic biological reactor comprising an anaerobic digester having a chamber configured to receive a microbial suspension, a chamber inlet configured to direct an organic waste stream into the digester, and ion-exchange fibers within the chamber in position to contact and chemically react with microbial suspension received into the chamber. A method for treating organic waste with a methane-producing anaerobic biological reactor comprise providing a methane-producing anaerobic biological reactor comprising an anaerobic digester containing a microbial suspension comprising acetogenic bacteria, methanogenic bacteria and a plurality of ion exchange fibers, introducing organic waste into the anaerobic digester, maintaining the microbial suspension in contact with the organic waste and at least a portion of the plurality of ion-exchange fibers for a period of time and under conditions sufficient to treat the organic waste and produce methane, and removing the treated organic waste and methane from the anaerobic digester.. ... Lehigh University

Gas separation apparatus and methods using same

The present invention includes apparatuses and methods to separate a gas from a gaseous mixture using supercapacitive swing adsorption.. . ... Lehigh University

Infrared characterization of a sample using oscillating mode

An apparatus and method of performing sample characterization with an afm and a pulsed ir laser directed at the tip of a probe of the afm. The laser pulses are synchronized with the oscillatory drive of the afm and may only interact with the tip/sample on selected cycles of the oscillation. ... Lehigh University

Isolated enzymatic manufacture of semiconductor nanoparticles

Novel semiconductor nanoparticles and methods of biosynthesizing the same are provided by biosynthetic processes using cell-free supernatants and isolated enzymes.. . ... Lehigh University

Conjugates of ph low insertion peptide and monomethyl auristatins in the treatment of solid tumors

Constructs comprising ph low insertion peptide and variants thereof conjugated to monomethyl auristatins and analogs thereof are described. These constructs are useful, for example, in the treatment of solid tumors, including the treatment of breast cancer and prostate cancer, as well as other cancers such as pancreatic cancer, ovarian cancer, cervical cancer, uterine cancer, lung cancer, skin cancer, kidney cancer, and colon cancer. ... Lehigh University

Thermally stable enzymes, compositions thereof and method of using same

Described herein are isolated recombinant proteins having lyase activity and nucleic acid sequences which code therefor; along with methods of expressing, isolating, purifying, and using same.. . ... Lehigh University

Microfluidic concentrator for label-free, continuous naonoparticle processing

Disclosed herein are apparatuses comprising, for example, a microfluidic channel device comprising a main body comprising a channel configured to provide for helical fluid motion of material within the channel; and a temperature control system that applies a temperature gradient to the channel. Methods of making and using the apparatus are also described.. ... Lehigh University

Methods of growing single crystals using solid-solid transformation of a glass

The present invention includes methods of promoting single crystal growth via solid-solid transformation of an appropriate glass, while avoiding the gaseous or liquid phase. In certain embodiments, in the all-solid-state glass-to-crystal transformation of the invention, extraneous nucleation is avoided relative to crystal growth via spatially localized laser heating and optional inclusion of a suitable glass former in the composition. ... Lehigh University

Augmenting moieties for anti-inflammatory compounds

Augmented or synergized anti-inflammatory constructs are disclosed including anti-inflammatory amino acids covalently conjugated with other anti-inflammatory molecules such as nonsteroidal anti-inflammatory drugs, vanilloids and ketone bodies. Further conjugation with a choline bioisostere or an additional anti-inflammatory moiety further augments the anti-inflammatory activity.. ... Lehigh University

Reduced toxicity molecular conjugates of anti-fungal agents

Compositions, compounds and methods are described for addressing both toxicity of membrane disruptive anti-microbial agents as well as poor transport of such agents across the blood-brain-barrier (bbb) via the use of molecular appendages including one or more facial amphiphiles. These molecules have in vitro anti-fungal activity that is very similar to that of the native drug but with hemolytic activity and toxicity towards mammalian cells that is greatly reduced.. ... Lehigh University

Bioactive glass preparation and use

A process of preparing a glass comprising: (a) heating a mixture of precursor chemicals to a melt temperature to form a melt, the melt being characterized in that quenching the melt at or above a threshold temperature results in a spinodal phase separation, and quenching the melt below the threshold temperature results in a droplet phase separation; and (b) quenching the melt at or above the threshold temperature in a preheated mold to form the glass composition having the spinodal phase separation.. . ... Lehigh University








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