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Medtronic Ardian Luxembourg S a r l patents


Recent patent applications related to Medtronic Ardian Luxembourg S a r l. Medtronic Ardian Luxembourg S a r l is listed as an Agent/Assignee. Note: Medtronic Ardian Luxembourg S a r l may have other listings under different names/spellings. We're not affiliated with Medtronic Ardian Luxembourg S a r l, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "M" | Medtronic Ardian Luxembourg S a r l-related inventors


Methods and renal neuromodulation

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive... Medtronic Ardian Luxembourg S a r l

Methods for assessing efficacy of renal neuromodulation and associated systems and devices

Provided herein are methods, devices and compositions for assessing neuromodulation efficacy based on changes in the level of one or more biomarkers in plasma or urine collected from a human subject following a renal neuromodulation procedure.... Medtronic Ardian Luxembourg S a r l

Methods and monopolar renal neuromodulation

Methods and apparatus are provided for monopolar neuromodulation, e.g., via a pulsed electric field. Such monopolar neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some... Medtronic Ardian Luxembourg S a r l

Ovarian neuromodulation and associated systems and methods

Methods for treating polycystic ovary syndrome with therapeutic ovarian neuromodulation and associated systems and methods are disclosed herein. Polycystic ovary syndrome can be associated, for example, with a condition including at least one of oligo/amenorrhea, infertility, hirsutism, obesity, metabolic syndrome, insulin resistance, and increased cardiovascular risk profile. One aspect of... Medtronic Ardian Luxembourg S a r l

Systems and methods for assessing sympathetic nervous system tone for neuromodulation therapy

Systems and methods for assessing sympathetic nervous system (SNS) tone for renal neuromodulation therapy are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a detector attached to or implanted in a patient and a receiver communicatively coupled to the detector. The... Medtronic Ardian Luxembourg S a r l

Methods and renal neuromodulation

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive... Medtronic Ardian Luxembourg S a r l

Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation

Apparatus, systems, and methods for achieving thermally-induced renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a thermal... Medtronic Ardian Luxembourg S a r l

Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation

Apparatus, systems, and methods for achieving thermally-induced renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a thermal... Medtronic Ardian Luxembourg S a r l

Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation

Apparatus, systems, and methods for achieving thermally-induced renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a thermal... Medtronic Ardian Luxembourg S a r l

Endovascular nerve monitoring devices and associated systems and methods

Endovascular nerve monitoring devices and associated systems and methods are disclosed herein. A nerve monitoring system configured in accordance with a particular embodiment of the present technology can include a shaft having a proximal portion and a distal portion and a nerve monitoring assembly at the distal portion. The shaft... Medtronic Ardian Luxembourg S a r l

Neuromodulation and associated the treatment of cancer

Methods for treating a human patient diagnosed with cancer with therapeutic neuromodulation and associated systems are disclosed herein. Sympathetic nerve activity can contribute to several cellular and physiological processes associated with the progression of cancer. One aspect of the present technology is directed to methods that attenuate neural traffic along... Medtronic Ardian Luxembourg S a r l

Cryotherapeutic devices for renal neuromodulation and associated systems and methods

Cryotherapeutic devices for renal neuromodulation and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having a distal portion and a supply lumen along at least a portion of the shaft. The shaft... Medtronic Ardian Luxembourg S a r l

Renal neuromodulation for treatment of patients

A method and apparatus for treatment of heart failure, hypertension and renal failure by stimulating the renal nerve. The goal of therapy is to reduce sympathetic activity of the renal nerve. Therapy is accomplished by at least partially blocking the nerve with drug infusion or electrostimulation. Apparatus can be permanently... Medtronic Ardian Luxembourg S a r l

Catheter apparatuses, systems, and methods for renal neuromodulation

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver an... Medtronic Ardian Luxembourg S a r l

Methods for therapeutic renal denervation

Methods for therapeutic renal denervation are disclosed herein. One aspect of the present application, for example, is directed to methods that block, reduce and/or inhibit renal sympathetic nerve activity to achieve a reduction in central sympathetic tone. Renal sympathetic nerve activity may be altered or modulated along the afferent and/or... Medtronic Ardian Luxembourg S a r l

Methods for therapeutic renal neuromodulation

Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential... Medtronic Ardian Luxembourg S a r l

Methods and bilateral renal neuromodulation

Methods and apparatus are provided for bilateral renal neuromodulation, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action... Medtronic Ardian Luxembourg S a r l

Methods for therapeutic renal neuromodulation

Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential... Medtronic Ardian Luxembourg S a r l

Systems and methods for monitoring and evaluating neuromodulation therapy

Systems and methods for informing and evaluating neuromodulation therapy are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a guidewire having a proximal portion, a distal portion configured to be positioned at a target site in a blood vessel of a... Medtronic Ardian Luxembourg S a r l

Biomarker sampling in the context of neuromodulation devices, systems, and methods

Methods for treating a patient using therapeutic renal neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to biomarker sampling in the context of neuromodulation devices, systems, and methods. Some embodiments, for example, are directed to catheters, catheter systems, and methods... Medtronic Ardian Luxembourg S a r l

Methods for renal neuromodulation via neuromodulatory agents

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters... Medtronic Ardian Luxembourg S a r l

Anti-resterilization components for catheter treatment devices and associated devices, systems, and methods

Anti-resterilization components for medical devices, such as catheter assemblies, are disclosed herein. In one embodiment, for example, a catheter assembly comprises a handle assembly and an anti-resterilization component within the handle assembly. The anti-resterilization component comprises an absorptive material configured to absorb and selectively retain a component of a sterilization... Medtronic Ardian Luxembourg S a r l

Monitoring of neuromodulation using biomarkers

Provided herein are methods, devices, compositions, and kits for monitoring neuromodulation efficacy based on changes in the level or activity of one or more target biomarkers.... Medtronic Ardian Luxembourg S a r l

Low profile catheter assemblies and associated systems and methods

Catheters including elements configured to deliver energy to nerves at or near a treatment location within a body lumen. A treatment assembly is transformable between a low-profile delivery configuration wherein a pair of electrodes are in a staggered arrangement relative to each other along the longitudinal axis, and an expanded... Medtronic Ardian Luxembourg S a r l

Multi-electrode apposition judgment using pressure elements

Apparatus and methods for determining positioning of a energy delivery element include deploying a energy delivery element at a treatment site proximal to a vessel wall; using a multi-region pressure sensing apparatus to sense pressures applied in a plurality of directions about the energy delivery element; and determining an orientation... Medtronic Ardian Luxembourg S a r l

Catheter-based devices and associated methods for immune system neuromodulation

Catheter-based devices and associated methods for immune system neuromodulation of human patients are disclosed herein. One aspect of the present technology is directed to methods of treating a human patient diagnosed with an immune system condition. The methods can include intravascularly positioning a neuromodulation catheter within a blood vessel proximate... Medtronic Ardian Luxembourg S a r l

Methods and bilateral renal neuromodulation

Methods and apparatus are provided for bilateral renal neuromodulation, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action... Medtronic Ardian Luxembourg S a r l

Methods for renal neuromodulation

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive... Medtronic Ardian Luxembourg S a r l

Methods for therapeutic renal neuromodulation

Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential... Medtronic Ardian Luxembourg S a r l

Methods for catheter-based renal neuromodulation

Methods and apparatus are provided for monopolar neuromodulation, e.g., via a pulsed electric field. Such monopolar neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some... Medtronic Ardian Luxembourg S a r l

Neuromodulation cryotherapeutic devices and associated systems and methods

Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured... Medtronic Ardian Luxembourg S a r l

Catheters with enhanced flexibility and associated devices, systems, and methods

A neuromodulation catheter includes an elongate shaft and a neuromodulation element. The shaft includes two or more first cut shapes and two or more second cut shapes along a helical path extending around a longitudinal axis of the shaft. The first cut shapes are configured to at least partially resist... Medtronic Ardian Luxembourg S a r l

Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present technology, for example, is directed to a treatment device having a multi-electrode array configured to be delivered to a renal blood vessel. The array is selectively transformable between a delivery... Medtronic Ardian Luxembourg S a r l

Devices, evaluation and feedback of neuromodulation treatment

The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a... Medtronic Ardian Luxembourg S a r l

Methods and multi-vessel renal neuromodulation

Methods and apparatus are provided for multi-vessel neuromodulation, e.g., via a pulsed electric field. Such multi-vessel neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some... Medtronic Ardian Luxembourg S a r l

01/19/17 / #20170014177

Methods and systems for thermally-induced renal neuromodulation

Methods and system are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters... Medtronic Ardian Luxembourg S a r l

01/12/17 / #20170007319

Renal neuromodulation for treatment of patients

A method and apparatus for treatment of heart failure, hypertension and renal failure by stimulating the renal nerve. The goal of therapy is to reduce sympathetic activity of the renal nerve. Therapy is accomplished by at least partially blocking the nerve with drug infusion or electrostimulation. Apparatus can be permanently... Medtronic Ardian Luxembourg S a r l

01/12/17 / #20170007320

Renal neuromodulation for treatment of patients

A method and apparatus for treatment of heart failure, hypertension and renal failure by stimulating the renal nerve. The goal of therapy is to reduce sympathetic activity of the renal nerve. Therapy is accomplished by at least partially blocking the nerve with drug infusion or electrostimulation. Apparatus can be permanently... Medtronic Ardian Luxembourg S a r l

01/12/17 / #20170007325

Microwave catheter apparatuses, systems, and methods for renal neuromodulation

Microwave catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver... Medtronic Ardian Luxembourg S a r l








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