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Merck Sharp x26 Dohme Corp
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Merck Sharp & Dohme Corp patents

Recent patent applications related to Merck Sharp & Dohme Corp. Merck Sharp & Dohme Corp is listed as an Agent/Assignee. Note: Merck Sharp & Dohme Corp may have other listings under different names/spellings. We're not affiliated with Merck Sharp & Dohme Corp, we're just tracking patents.

ARCHIVE: New 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "M" | Merck Sharp & Dohme Corp-related inventors




Date Merck Sharp & Dohme Corp patents (updated weekly) - BOOKMARK this page
07/07/16Mono- and di-peg il-10 production; and uses
03/26/15Mono- and di-peg il-10 production; and uses
01/08/15Dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
10/04/12Novel cationic lipids with short lipid chains for oligonucleotide delivery
08/09/12Combination therapy using a beta 3 adrenergic receptor agonists and an antimuscarinic agent
10/12/17Anti-lag3 antibodies and antigen-binding fragments
10/05/17Inhibitors of the renal outer medullary potassium channel
09/28/17Tetrahydroisoquinoline derivatives useful as inhibitors of diacylglyceride o-acyltransferase 2
09/28/17Tetrahydroisoquinoline derivatives useful as inhibitors of diacylglyceride o-acyltransferase 2
09/28/17Combination of a pd-1 antagonist and an alk inhibitor for treating cancer
09/28/17Allosteric modulators of nicotinic acetylcholine receptors
09/28/17Isoquinoline derivatives useful as inhibitors of diacylglyceride o-acyltransferase 2
09/28/17Inhibitors of the renal outer medullary potassium channel
09/28/17Inhibitors of the renal outer medullary potassium channel
09/28/17Inhibitors of irak4 activity
09/28/17Inhibitors of the renal outer medullary potassium channel
09/28/17Synthesis of cephalosporin compounds
09/28/17Inhibitors of the renal outer medullary potassium channel
09/28/17Forms of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate
09/28/17Substituted phosphoramidate compounds and uses thereof
09/21/17Erk inhibitors
09/21/17Erk inhibitors
09/21/17Anti-lag3 antibodies and antigen-binding fragments
09/14/17Heteroaryl orexin receptor antagonists
09/14/17Methyl oxazole orexin receptor antagonists
09/14/17S-imino-s-oxo iminothiazine compounds as bace inhibitors, compositions, and their use
09/07/17Method for screening drug-saccharide conjugates
08/31/17Process for making nucleoside phosphoramidate compounds
08/31/17C5-c6-fused tricyclic iminothiadiazine dioxide compounds as bace inhibitors, compositions, and their use
08/31/17Substituted pyrimidines as inhibitors of hif prolyl hydroxylase
08/31/17Diazine-fused amidines as bace inhibitors, compositions, and their use
08/31/17Inhibitors of irak4 activity
08/31/17Method for screening drug-saccharide conjugates
08/24/17Substituted pyridine inhibitors of hif prolyl hydroxylase
08/24/17Substituted pyrimidines as inhibitors of hif prolyl hydroxylase
08/24/17Factor xia inhibitors
08/24/17Factor xia inhibitors
08/24/17Preparation and use of cyclic sulfonamide derivatives as par-1 receptor antagonists
08/24/17Inhibitors of hif prolyl hydroxylase
08/24/17Ethyl n-boc piperidinyl pyrazolo pyridones as janus kinase inhibitors
08/17/17Solid pharmaceutical compositions containing an integrase inhibitor
08/17/17Processes for the preparation of a bace inhibitor
08/17/17Novel crystalline forms of a bace inhibitor, compositions, and their use
08/17/17Salt forms of ceftolozane
08/17/17Inhibitors of hif prolyl hydroxylase
08/17/17Cell line 3m
08/10/17Novel crystalline forms of a bace inhibitor, compositions, and their use
08/10/17Inhibitors of hif prolyl hydroxylase
08/10/17Intermediates in the synthesis of cephalosporin compounds
08/10/17Anti-coagulation factor xi antibodies
08/10/17Inhibitory rna for enhanced protein production in recombinant mammalian cells
08/03/17Methods of treating diabetes by administering a glucagon receptor antagonist in combination with a cholesterol absorption inhibitor
08/03/17Ccr9 antagonist compounds
08/03/17Antidiabetic bicyclic compounds
08/03/17Antidiabetic bicyclic compounds
08/03/17Fused tetracyclic heterocyclic compounds and methods of use thereof for the treatment of viral diseases
08/03/17[7,6]-fused bicyclic antidiabetic compounds
08/03/17Inhibitors of irak4 activity
08/03/17Hiv protease inhibitors
07/27/17Inhibitors of irak4 activity
07/27/17Inhibitors of irak4 activity
07/27/17Method for preparing crystalline insulin or insulin analog compositions
07/27/17Monocyclic isoxazolines as inhibitors of cholesterol ester transfer protein
07/27/17[5,6]-fused bicyclic antidiabetic compounds
07/27/17Factor xia inhibitors
Patent Packs
07/20/17Mono- and di-peg il-10 production; and uses
07/13/17Prefilled disposable injection device
07/13/17Factor xia inhibitors
07/13/17Inhibitors of the renal outer medullary potassium channel
07/13/17Inhibitors of the renal outer medullary potassium channel
07/13/17Heterobicyclo-substituted [1,2,4]triazolo[1,5-c]quinazolin-5-amine compounds with a2a antagonist properties
07/13/17Anti-tigit antibodies
07/06/17Dual molecular delivery of oligonucleotides and peptide containing conjugates
06/29/17Phosphate based linkers for intracellular delivery of drug conjugates
06/29/17Nucleoside derivatives as inhibitors of rna-dependent rna viral polyermase
06/22/17Prodrugs of hiv reverse transcriptase inhibitors
06/22/17Beta-tetrazolyl-propionic acids as metallo-beta-lactamase inhibitors
06/22/17Hydroxyalkylamine- and hydroxycycloalkylamine-substituted diamine-arylsulfonamide compounds with selective activity in voltage-gated sodium channels
06/22/17Chromatography process for purification of insulin and insulin analogs
06/22/17Combination of a pd-1 antagonist and a 4-1bb agonist for treating cancer
Patent Packs
06/15/17Antidiabetic substituted heteroaryl compounds
06/15/17Process for making tetracyclic heterocycle compounds
06/15/17Combination of a pd-1 antagonist and a vegfr inhibitor for treating cancer
06/08/17Hpv vaccine formulations comprising aluminum adjuvant and methods of producing same
06/08/17Alpha-7 nicotinic acetylcholine receptor modulators and uses thereof-i
06/08/17Trka kinase inhibitors, compositions and methods thereof
06/08/17Process for preparing chiral dipeptidyl peptidase-iv inhibitors
06/08/17Immunoregulation by anti-ilts antibodies and ilts-binding antibody fragments
06/01/17Alpha-7 nicotinic acetylcholine receptor modulators and uses thereof
05/25/17Process for preparing beta 3 agonists and intermediates
05/18/17Regioselective n-2 arylation of indazoles
05/11/17Reactions of thiadiazolyl-oximinoacetic acid derivative compounds
05/04/17Pyrrolo[2,3-c]pyridines as imaging agents for neurofibrillary
05/04/17Antibody neutralizing human respiratory syncytial virus
04/27/17Trka kinase inhibitors, compositions and methods thereof
04/27/17C2-carbocyclic iminothiazine dioxides as bace inhibitors, compositions, and their use
04/27/17Trka kinase inhibitors, compositions and methods thereof
04/27/17Purine inhibitors of human phosphatidylinositol 3-kinase delta
04/20/17Glycosidase inhibitors and uses thereof
04/20/17Trka kinase inhibitors, compositions and methods thereof
04/20/17Imidazo-pyrazine derivatives useful as soluble guanylate cyclase activators
04/20/17Insulin receptor partial agonists
04/20/17Surface display of whole antibodies in eukaryotes
04/06/17Methods for treating cancer with a wee1 inhibitor
04/06/17Dry powder inhaler with dose depletion evaluation
04/06/17Cell based assay to measure the t-cell stimulating capacity of anti-lag3 antibodies and other agents
03/30/17Polymeric nanoparticles and methods of making and using same
03/30/17Anti-pembrolizumab antibodies
03/23/17Antidiabetic tricyclic compounds
03/23/17Peptide containing conjugates for dual molecular delivery of oligonucleotides
Social Network Patent Pack
03/16/172-pyrazine carboxamides as spleen tyrosine kinase inhibitors
03/16/17Piperazine derivatives as hiv protease inhibitors
03/16/17Triazolo-pyrazinyl derivatives useful as soluble guanylate cyclase activators
03/09/17Amidation process
03/09/17Solid prodrug forms of 2'-chloro-2'-methyl uridine for hcv
03/02/17Method for treating cancer
02/16/17Sitagliptin tannate complex
02/16/17Pharmaceutical salts of an orexin receptor antagonist
02/16/17Factor xia inhibitors
02/16/17Antiviral beta-amino acid ester phosphodiamide compounds
Patent Packs
02/16/17Cyclic di-nucleotide compounds as sting agonists
02/09/17Inhibitors of the renal outer medullary potassium channel
02/09/17Iminothiadiazepane dioxide compounds as bace inhibitors, compositions, and their use
02/09/17Gyrase inhibitors
02/02/17Factor ixa inhibitors
02/02/17Piperidinone carboxamide azaindane cgrp receptor antagonists
01/26/17Apparatus and preserving mucosa
01/26/17Pyrazolopyridyl compounds as aldosterone synthase inhibitors
01/19/17Pyrimidone carboxamide compounds as pde2 inhibitors
01/19/17Purifying insulin using cation exchange and reverse phase chromatography in the presence of an organic modifier and elevated temperature
01/12/17Prefilled disposable injection device
01/12/17Fused tricyclic compounds and methods of use thereof for the treatment of viral diseases
01/12/17Btk inhibitors
01/12/17Inhibitors of hepatitis c virus replication
01/05/17Bicycloamine-substituted-n-benzenesulfonamide compounds with selective activity in voltage-gated sodium channels
12/29/16Methods for producing high concentration lyophilized pharmaceutical formulations
12/29/16Factor xia inhibitors
12/22/16Iminothiadiazine dioxide compounds as bace inhibitors, compositions, and their use
12/22/16Use of pegylated il-10 to treat cancer
12/22/162-pyridyloxy-4-methyl orexin receptor antagonists
12/15/16Lipid nanoparticle vaccine adjuvants and antigen delivery systems
12/15/16Formulations of acadesine
12/08/163,3'-disubstituted indolines as inhibitors of cholesterol ester transfer protein
12/08/16Cathepsin cysteine protease inhibitors
12/08/16Anti-tigit antibodies
12/08/16Crz1 mutant fungal cells
12/08/16Antibodies that bind to human tau and assay for quantifying human tau using the antibodies
12/01/16Factor xia inhibitors
12/01/16Novel disintegration systems for pharmaceutical dosage forms
12/01/16Tablet formulation for cgrp active compounds
Patent Packs
12/01/16Fixed-dose combinations of antiviral compounds
12/01/16Factor xia inhibitors
11/24/16Pharmaceutical composition of selective hcv ns3/4a inhibitors
11/24/16Factor xia inhibitors
11/24/16Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
11/17/16Antidiabetic compounds
11/17/16Metallo-beta-lactamase inhibitors
11/10/16Inhibitors of the renal outer medullary potassium channel
11/10/16C-6 spirocarbocyclic iminothiadiazine dioxides as bace inhibitors, compositions, and their use
11/10/16Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
11/10/16Btk inhibitors
11/03/16Media milling process for the manufacture of active pharmaceutical ingredients in propellants
11/03/16Liposomal formulations for allosteric akt inhibitors
11/03/16Spirocyclic hetercycle compounds useful as hiv integrase inhibitors
11/03/16Thioether-piperidinyl orexin receptor antagonists
11/03/162-amino-3-ester-pyridyl orexin receptor antagonists
11/03/16Diazepane orexin receptor antagonists
11/03/16Piperidinyloxy lactone orexin receptor antagonists
11/03/16Fused bicyclic isoxazolines as inhibitors of cholesterol ester transfer protein
10/27/16Hiv protease inhibitors
Social Network Patent Pack
10/27/16Carbamate benzoxazine propionic acids and acid derivatives for modulation of rorgamma activity and the treatment of disease
10/27/16Novel tricyclic calcium sensing receptor antogonists for the treatment of osteopososis
10/27/16Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
10/27/16Erk inhibitors
10/27/16Btk inhibitors
10/27/16Gene signature biomarkers of tumor response to pd-1 antagonists
10/27/16Pd-l1 gene signature biomarkers of tumor response to pd-1 antagonists
10/20/16Treating cancer with a combination of a pd-1 antagonist and a vegfr inhibitor
10/20/16Glucose-responsive insulin conjugates
10/20/16Tetrahydronaphthyridine, benzoxazine, aza-benzoxazine and related bicyclic compounds for inhibition of rorgamma activity and the treatment of disease
10/20/16Indoline compounds as aldosterone synthase inhibitors
10/20/162-pyridyloxy-3-ester-4-ether orexin receptor antagonists
10/20/162-acylamidomethyl and sulfonylamidomethyl benzoxazine carbamates for inhibition of rorgamma activity and the treatment of disease
10/20/16Inhibitors of the renal outer medullary potassim channel
10/20/16Soluble guanylate cyclase activators
10/20/16Soluble guanylate cyclase activators
10/20/16Ifn-gamma gene signature biomarkers of tumor response to pd-1 antagonists
10/20/16Immunohistochemical proximity assay for pd-1 positive cells and pd-ligand positive cells in tumor tissue
10/13/16Hiv protease inhibitors
10/13/16Piperidine or piperazine linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug
Social Network Patent Pack
10/13/16Process for making reverse transcriptase inhibitors
10/13/16Aryl linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug
10/13/16Method for preparing crystalline insulin
10/06/16Composition of a non-nucleoside reverse transcriptase inhibitor
10/06/16Compounds inhibiting leucine-rich repeat kinase enzyme activity
10/06/16N-glycosylated insulin analogues
09/29/16Ceftolozane antibiotic compositions
09/29/16Antidiabetic bicyclic compounds
09/29/16Cycloalkyl nitrile pyrazolo pyridones as janus kinase inhibitors
09/29/16Novel antibacterial agents
09/22/16Geminally substituted cyanoethylpyrazolo pyridones as janus kinase inhibitors
09/22/16N-(2-cyano heterocyclyl) pyrazolo pyridones as janus kinase inhibitors
09/22/16Acyclic cyanoethylpyrazolo pyridones as janus kinase inhibitors
09/15/16C6-spiro iminothiadiazine dioxides as bace inhibitors, compositions, and their use
09/08/16Antidiabetic tricyclic compounds
09/08/16Factor xia inhibitors
09/08/16Inhibitors of the renal outer medullary potassium channel
09/08/16Thiophene-substituted tetracyclic compounds and methods ofuse thereof for the treatment of viral diseases
09/08/16Process for preparing tetracyclic heterocycle compounds
09/01/16Glucose-responsive insulin conjugates
09/01/16Thermostable respiratory synctial virus (rsv) vaccine compositions
09/01/16Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
09/01/16Thermostable respiratory synctial virus (rsv) vaccine compositions
09/01/16Methods and intermediates for preparing macrolactams
09/01/16Glucose-responsive insulin conjugates
09/01/16Method of microwave vacuum drying spherical-shaped pellets of biological materials
09/01/16Complimentary trade drug delivery system
08/25/16Polycyclic heterocycle derivatives and methods of use thereof for the treatment of viral diseases
08/25/16Cathepsin cysteine protease inhibitors
08/18/16Novel pyrrolidine derived beta 3 adrenergic receptor agonists
Social Network Patent Pack
08/11/16Trka kinase inhibitors, compositions and methods thereof
08/11/16Substituted quinolizine derivatives useful as hiv integrase inhibitors
08/11/16Solid forms of ceftolozane
08/11/16Method of obtaining thermostable dried vaccine formulations
08/11/16Trka kinase inhibitors, compositions and methods thereof
08/11/16Aryl methyl benzoquinazolinone m1 receptor positive allosteric modulators
08/11/16Factor xia inhibitors
08/11/16Trka kinase inhibitors, compositions and methods thereof
08/04/16Formulations for cgrp receptor antagonists
08/04/16Tricyclic gyrase inhibitors
08/04/16C5-spiro iminothiazine dioxides as bace inhibitors, compositions, and their use
07/28/162-pyridyloxy-4-ester orexin receptor antagonists
07/28/162,2-difluorodioxolo a2a receptor antagonists
07/28/16Fc containing polypeptides having increased binding to fcgammariib
07/21/16Antidiabetic tricyclic compounds
07/21/16Inhibitors of the renal outer medullary potassium channel
07/21/16Purine inhibitors of human phosphatidylinositol 3-kinase delta
07/14/16Modulation of tumor immunity
07/14/16Preparation and use of 3-pyridyl substituted- 6,6-difluoro bicyclic himbacine derivatives as par-1 receptor antagonists
07/14/16Preparation and use of 7a-heterocycle substituted- 6,6-difluoro bicyclic himbacine derivatives as par-1 receptor antagonists
07/14/16Compounds inhibiting leucine-rich repeat kinase enzyme activity
07/07/16Ceftolozane-tazobactam pharmaceutical compositions
07/07/16Immediate-release tablet formulations of a thrombin receptor antagonist
07/07/16Methods of immunization with varicella zoster virus antigen
07/07/16Treating cancer with a combination of a pd-1 antagonist and dinaciclib
07/07/16Piperazine-substituted [1,2,4]triazolo[1,5-c]quinazolin-5-amine compounds with a2a antagonist properties
07/07/16Methods and compositions for co-expression of polypeptides of inerest and il6
07/07/16Expression vectors for recombinant protein production in mammalian cells
06/30/16Preparation and use of 7a-amide substituted- 6,6-difluoro bicyclic himbacine derivatives as par-1 receptor antagonists







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