Mor Research Applications patents

Compositions and methods for prognosis of ovarian cancer

Described herein are compositions and methods for the prediction of the prognosis of ovarian cancer subjects. The present invention farther provides methods for distinguishing between histological subtypes of ovarian cancer tumors, and also methods and compositions liar the treatment or prevention of ovarian cancer. Specifically the invention relates to microRNA... Mor Research Applications

Percutaneous modification of vascular extracellular matrix to prevent and treat vascular restenosis

Aspects of disclosed embodiments relate to systems, devices and methods for treating and preventing restenosis by cross-linking collagen fibrils of the vessel wall at the intervention site. The devices described are drug-eluting devices comprising: an expandable member or a balloon; a cross-linking agent; and a photoactivating light source. Upon the... Mor Research Applications

Vital sign monitoring apparatuses and methods of using same

A system for vital sign measuring of a patient, comprising: a first sensor removably attachable with a first body portion of the patient and configured to measure, when in operable position, a vital sign of the patient; at least one additional sensor removably attachable with a second body portion of... Mor Research Applications

Compositions and methods for treating post-operative complications of cardiopulmonary surgery

Compositions and methods for treating damage inflicted by use of a cardio-pulmonary bypass (CPB) machine, particularly excessive bleeding and multi organ failure, by administering a pharmaceutical composition comprising alpha-1 antitrypsin (AAT-1).... Mor Research Applications

Interactive segmentation

A method for three-dimensional interactive segmentation, including: receiving a three-dimensional medical image of an interior volume of a patient's body; automatically performing three dimensional segmentation on the three dimensional medical image to detect and define a region of interest, wherein the performing of the three dimensional segmentation comprises automatically determining... Mor Research Applications

Compositions and methods for treatment of retinal degenerative diseases

This disclosure relates to compositions for use in treatment of Alzheimer's Disease, and/or a ocular and retinal degenerative disease, such as age related macular degeneration. The described compositions include effective amounts of LLMe, the hydrobromide form thereof, or functional derivatives thereof. Methods of treatment of a retinal degenerative disease of... Mor Research Applications

Prognostic methods and systems of treatment for acute lymphoblastic leukemia

Described herein are methods for determining the prognosis of a patient diagnosed with Acute Lymphoblastic Leukemia (ALL), and particularly determining the risk of disease relapse following standard treatment. Also described are systems of treatment that are directed by a health care provider, and which include the described prognostic methods and... Mor Research Applications

Compositions for treatment of acute lymphoblastic leukemia and methods of use thereof

Provided herein are compositions for treatment of Acute Lymphoblastic Leukemia (ALL) and methods of their use, including inhibiting ALL relapse. Further provided herein are systems of treatment that are directed by a health care provider, and which combine prognostic methods for determining ALL relapse and the described treatments.... Mor Research Applications

Extracellular matrix metalloproteinase inducer (emmprin) peptides and binding antibodies

Isolated peptides from the protein EMMPRIN (CD147/Basigin) and antibodies directed against antigenic determinants within the peptides. Pharmaceutical compositions including the peptides and antibodies and methods of their production and use in vaccination, immunotherapy and diagnosis of proliferative, hyperpermeability, inflammatory, and angiogenesis-related diseases and disorders.... Mor Research Applications

Methods of using pigment epithelium derived factor (pedf) for the treatment and prevention of agent-induced gonadal or uterine toxicity

A method of treating or preventing gonadal or uterine toxicity induced by an agent in a subject is provided. Accordingly there is provided a method comprising administering to a subject a therapeutically effective amount of pigment epithelium-derived factor (PEDF), thereby treating or preventing the gonadal toxicity induced by the agent.... Mor Research Applications

Butyroyloxymethyl diethyl phosphate compounds and uses thereof

Methods for treating ameliorating, reducing and/or preventing a cutaneous T-cell lymphoma in a subject in need thereof, comprising administration butyroyloxymethyl diethyl phosphate (AN-7) alone or combined with an additional anti-cancer therapy.... Mor Research Applications