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Nationwide Children s Hospital Inc
Nationwide Children s Hospital

Nationwide Children s Hospital patents


Recent patent applications related to Nationwide Children s Hospital. Nationwide Children s Hospital is listed as an Agent/Assignee. Note: Nationwide Children s Hospital may have other listings under different names/spellings. We're not affiliated with Nationwide Children s Hospital, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "N" | Nationwide Children s Hospital-related inventors


Delivery of polynucleotides using recombinant aav9

The present invention relates to Adeno-associated virus 9 methods and materials useful for systemically delivering polynucleotides across the blood brain barrier. Accordingly, the present invention also relates to methods and materials useful for systemically delivering polynucleotides to the central and peripheral nervous systems. The present invention also relates to Adeno-associated... Nationwide Children s Hospital

Intrathecal delivery of recombinant adeno-associated virus 9

The present invention relates to Adeno-associated virus type 9 methods and materials useful for intrathecal delivery of polynucleotides. Use of the methods and materials is indicated, for example, for treatment of lower motor neuron diseases such as SMA and ALS as well as Pompe disease and lysosomal storage disorders. It... Nationwide Children s Hospital

Myostatin inhibition for enhancing muscle and/or improving muscle function

The present invention relates to methods for inhibitiing myostatin, a regulator of muscle mass, for muscle enhancement (including inducing hypertrophy and/or hyperplasia) as well as improving muscle function (including decreasing atrophy and/or increasing endurance, force and/or strength). Some of the methods involve delivering genes to cells using gene delivery or... Nationwide Children s Hospital

Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides

The present invention relates to recombinant adeno-associated virus (rAAV) delivery of an alpha-sarcoglycan gene. The invention provides rAAV products and methods of using the rAAV in the treatment of limb girdle muscular dystrophies such as LGMD2D.... Nationwide Children s Hospital

Proteomics based diagnostic detection chronic sinusitis

The invention provides for a proteomic approach for identification of specific bacterial protein profiles that may be used in the development of methods for the diagnosis of bacterial chronic sinusitis. The invention provides for methods for determining the presence of pathogenic bacteria in the upper respiratory tract of a subject... Nationwide Children s Hospital

Haemophilus influenzae type iv pili

The invention described herein relates to a Haemophilus influenzae (H. influenzae) regulon encoding type IV pili. In particular, the invention relates to type IV pili from nontypeable H. influenzae (NTHi) and from H. influenzae strains a, b, c, e and f. The invention provides isolated H. influenzae pilus polynucleotides and... Nationwide Children s Hospital

Recombinant virus products and methods for inhibition of expression of dux4

The present invention relates to RNA interference-based methods for inhibiting the expression of the DUX4 gene, a double homeobox gene on human chromosome 4q35. Recombinant adeno-associated viruses of the invention deliver DNAs encoding microRNAs that knock down the expression of DUX4. The methods have application in the treatment of muscular... Nationwide Children s Hospital








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