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Purdue Research Foundation patents


Recent patent applications related to Purdue Research Foundation. Purdue Research Foundation is listed as an Agent/Assignee. Note: Purdue Research Foundation may have other listings under different names/spellings. We're not affiliated with Purdue Research Foundation, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "P" | Purdue Research Foundation-related inventors


Vibration-based secure side channel for medical devices

According to some embodiments, a system for securing communications between an implantable wearable medical device (IWMD) and an external device (ED) is disclosed. The system includes a wireless radio frequency (RF) channel configured for communication between the IWMD and the ED. The system further includes a vibration-based side channel configured... Purdue Research Foundation

Systems and methods for increasing reaction yield

The invention generally relates to systems and methods for increasing reaction yield. In certain embodiments, the invention provides systems for increasing a yield of a chemical reaction that include a pneumatic sprayer configured to generate a liquid spray discharge from a solvent. The solvent includes a plurality of molecules, a... Purdue Research Foundation

Adhesives from renewable feedstocks

Disclosed herein is a novel copolymer: poly [(3,4-dihydroxymandelic acid)-co-(lactic acid)]. This novel copolymer can be produced from renewable feedstocks, possesses tunable degradation, and can achieve adhesion strengths rivaling the performance of existing glues and adhesives. In one aspect, a polymer is presented. The polymer includes poly[(3,4-dihydroxymandelic acid)-co-(lactic acid)]. The polymer... Purdue Research Foundation

Belt and pulley systems and methods of detecting belt damage

A system and method capable of detecting damage in a belt before catastrophic failure of the belt occurs. The system includes a belt having at least a first conductive component and/or at least a first dielectric component, and one or more pulleys to which the belt is mounted. At least... Purdue Research Foundation

High frame-rate multichannel beam-scanning microscopy

A beam-scanning optical design is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier... Purdue Research Foundation

Reaction monitoring

The invention generally relates to systems and methods for on-line reaction monitoring. In certain embodiments, the invention provides systems that include a reaction vessel having an outlet, a quantitation unit coupled to the outlet and configured to introduce internal standard and solvent into reaction solution flowed from the reaction vessel,... Purdue Research Foundation

Pressure sensors for small-scale applications and related methods

Certain pressure sensor devices are much smaller than prior art devices, yet are at least as sensitive as the prior art devices. A capacitive pressure sensor can include a flexible substrate that permits bending of a pressure sensing region without significantly affecting operation thereof. The pressure sensor can include a... Purdue Research Foundation

Systems and methods for relay ionization

The invention generally relates to systems and methods for relay ionization of a sample. In certain aspects, the invention provides systems that include an ion source that generates ions, a sample emitter configured to hold a sample, and a mass spectrometer. The system is configured such that the ions generated... Purdue Research Foundation

Methods and systems for fabricating elastomer-based electronic devices and devices formed thereby

Methods and systems suitable for fabricating multi-layer elastic electronic devices, and elastic electronic devices formed thereby. A method of fabricating an elastomer-based electronic device includes printing a first liquid material and then a second liquid material on a fabric substrate that comprises fibers. The first and second liquid materials are... Purdue Research Foundation

Collagen-binding synthetic peptidoglycans for use in vascular intervention

This invention relates to collagen-binding synthetic peptidoglycans. More particularly, this invention relates to collagen-binding synthetic peptidoglycans for use in vascular intervention procedures. The invention also relates to kits comprising such collagen-binding synthetic peptidoglycans and catheters or stents.... Purdue Research Foundation

Ink and conducting an examination

An ink and method of conducting an examination suitable for reducing the likelihood that the students' answers on paper-based examinations may be changed at a later time prior to being graded. The ink includes a solution of marking particles, a suspension material, and a preserving material. A mark made with... Purdue Research Foundation

Genetic locus associated with phytophthora root and stem rot in soybean

The present subject matter relates to methods and compositions for identifying soybean plants that having increased Phytophthora root and stem rot resistance. The methods use molecular markers to identify and to select plants with increased Phytophthora root and stem rot resistance or to identify and deselect plants with decreased Phytophthora... Purdue Research Foundation

Sample analysis systems and methods of use thereof

The invention generally relates to sample analysis systems and methods of use thereof. In certain aspects, the invention provides a system for analyzing a sample that includes an ion generator configured to generate ions from a sample. The system additionally includes an ion separator configured to separate at or above... Purdue Research Foundation

Reactive burning rate accelerators, solid energetic materials comprising the same, and methods of using the same

A reactive burning rate accelerator is provided that is configured to be at least partially embedded in a solid energetic material and comprises at least one metallic component and at least one non-metallic component. The reactive burning rate accelerator is configured to ignite and combust to increase the mass burning... Purdue Research Foundation

Methods for mitigating the inhibitory effects of lignin and soluble phenolics for enzymatic conversion of cellulose

Disclosed herein are methods for improving ethanol production from biomass sources by blocking cellulose from binding to lignin.... Purdue Research Foundation

Systems and methods for screening a sample based on multiple reaction monitoring mass spectrometry

The invention generally relates to systems methods for screening a sample based on multiple reaction monitoring mass spectrometry. In certain embodiments, the invention provides methods for screening a sample that involve ionizing a sample. Mass spectrometry is then used in order to monitor specific transitions connecting one or more ion... Purdue Research Foundation

Tomography system

Systems and methods for MBIR reconstruction utilizing a super-voxel approach are provided. A super-voxel algorithm is an optimization algorithm that, as with ICD, produces rapid and geometrically agnostic convergence to the MBIR reconstruction by processing super-voxels which comprise a plurality of voxels whose corresponding memory entries substantially overlap. The voxels... Purdue Research Foundation

Methods of reducing the electrical and thermal resistance of sic substrates and devices made thereby

A power semiconductor device includes a silicon carbide substrate and at least a first layer or region formed above the substrate. The silicon carbide substrate has a pattern of pits formed thereon. The device further comprising an ohmic metal disposed at least in the pits to form low-resistance ohmic contacts.... Purdue Research Foundation

Motor-activated multi-functional wrist orthotic

A multifunctional wrist orthotic comprising an electromyography (EMG) sensor having at least two electrodes for attachment to a wrist of a user, an intertial measurement sensor (IMU), a microcontroller unit (e.g., a Arduino® Mini) connected to the IMU, a power supply unit. The microcontroller unit is configured to perform two-tiered... Purdue Research Foundation

Continuous and scalable 3d nanoprinting

A rapidly printing 3D nanostructures arrangement, comprising a first photonic source configured to provide photoinitiation energy to a polymer medium via a dynamic light spatial modulator to an excited state to initiate polymerization, a second photonic source configured to selectively provide inhibition energy to the polymerized medium to a depleted... Purdue Research Foundation

Ion generation using modified wetted porous materials

The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation... Purdue Research Foundation

Non-spectroscopic imaging of plants

Monitoring stress symptoms in plants is crucial to maximize crop productivity. Nondestructive imaging of physiological changes in plants has been intensively used as invaluable tools in the agricultural industry. However, this approach requires a bulky and expensive optical instrument for capturing full spectral information and often has intrinsic limitations for... Purdue Research Foundation

Energy harvesting configurable image sensor

An image sensor is provided, comprising a plurality of photo-diode pixels arranged in a two-dimensional array, an energy harvesting output bus connected to the pixels, an image sensing output bus connected to the pixels, and a plurality of switching busses, the switching buses connected to the pixels to direct output... Purdue Research Foundation

Inp-based transistor fabrication

Methods of forming structures that include InP-based materials, such as a transistor operating as an inversion-type, enhancement-mode device are disclosed. A dielectric layer may be deposited by ALD over a semiconductor layer including In and P. A channel layer may be formed above a buffer layer having a lattice constant... Purdue Research Foundation

Non-toxic formulations of radio-luminescent nanoparticles for use as cancer radio-sensitizing agents

The invention relates generally to a formulation in which metal tungstate or metal molybdate particles are encapsulated within biocompatible, diseased cell-targeting polymeric coatings. Such formulations render metal tungstate or metal molybdate particles suitable for in vivo biomedical imaging and therapeutic applications.... Purdue Research Foundation

Probes, systems, cartridges, and methods of use thereof

The invention generally relates to probes, systems, cartridges, and methods of use thereof. In certain embodiments, the invention provides a probe including a porous material and a hollow member coupled to a distal portion of the porous material.... Purdue Research Foundation

Nems devices with series ferroelectric negative capacitor

An electrical circuit comprising at least two negative capacitance insulators connected in series, one of the two negative capacitance insulators is biased to generate a negative capacitance. One of the negative capacitance insulators may include an air-gap which is part of a nanoelectromechnical system (NEMS) device and the second negative... Purdue Research Foundation

Hybrid surface magnet machine

A hybrid electrical machine containing surface mounted magnets which includes a magnetically permeable cylindrically shaped stator assembly having at least one stator winding formed about a plurality of stator teeth, a rotor assembly concentrically disposed within the stator assembly, including a magnetically permeable rotor backiron, a rotational drive mechanism coupled... Purdue Research Foundation

Color table compression

In some examples, a print cartridge includes a memory device comprising quantized coefficients derived from a compression of a difference table including a plurality of difference nodes in which each difference node represents a value that is a difference of a value of a node of a color table and... Purdue Research Foundation

Printing device supply component

In some examples, a supply component for a printing device includes a memory device comprising a plurality of corrective data to produce a corresponding plurality of color tables each customized for a respective media type of a plurality of media types, wherein a respective corrective data of the plurality of... Purdue Research Foundation

Color table compression

In some examples, a print cartridge includes a memory device comprising quantized coefficients derived from a lossy compression, at a selected step size, of a difference color table including a plurality of difference nodes in which each difference node represents a difference value that is a difference of a value... Purdue Research Foundation

Plasmonic metal nitride and transparent conductive oxide nanostructures for plasmon assisted catalysis

A nanostructured material system for efficient collection of photo-excited carriers is provided. They system comprises a plurality of plasmonic metal nitride core material elements coupled to a plurality of semiconductor material elements. The plasmonic nanostructured elements form ohmic junctions at the surface of the semiconductor material or at close proximity... Purdue Research Foundation

Transient liquid phase bonding process and assemblies formed thereby

Processes of joining substrates via transient liquid phase bonding (TLPB). The processes include providing an interlayer of a low melting temperature phase (LTP) that includes Sn and Bi between and in contact with at least two substrates, and heating the substrates and the interlayer therebetween at a processing temperature equal... Purdue Research Foundation

Carrier-free nanoparticles

A carrier free nanoparticle formulation with good circulation stability is made for anticancer drug delivery. Nanocrystals crystalized in the medium containing Pluronic F-127 then coated with albumin (Cim-F-Alb) had the smallest size and the most native albumin, and showed most favorable cell interaction profiles and better stability than commercial albumin... Purdue Research Foundation

Nesting material baling and dispensing system for mouse environmental enrichment

A standardized nesting material for use in laboratory environments for rodents includes a latrining substrate, and at least one bale unit formed to include a fibrous scaffolding material, and an insulating material. The bale units are of standardized size and can be packaged and sterilized to provide improved wellbeing of... Purdue Research Foundation

12/14/17 / #20170354758

Glycosaminoglycan-based materials as an engineered biocompatible cellular matrix

Disclosed herein is a cross-linked polymeric system comprising thiolated hyaluronic acid (HA), thiolated chondroitin sulfate (CS), and functionalized polyethylene glycol (PEG), wherein said functionalized PEG cross-links thiolated HA and thiolated CS. Methods of fabrication and utilization of the same are also claimed. This polymeric system may be used as an... Purdue Research Foundation

12/07/17 / #20170349547

Conducting reactions in leidenfrost-levitated droplets

The invention generally relates to conducting reactions in Leidenfrost-levitated droplets.... Purdue Research Foundation

12/07/17 / #20170349903

Sirna compositions that specifically downregulate expression of a variant of the pnpla3 gene and methods of use thereof for treating a chronic liver disease or alcoholic liver disease (ald)

The invention provides siRNA compositions that specifically downregulates expression of a variant of the PNPLA3 gene and methods of use thereof for treating a chronic liver disease or alcoholic liver disease (ALD).... Purdue Research Foundation

11/30/17 / #20170342461

Tyrosine kinase biosensors and methods of use

Disclosed are compositions and methods for measuring tyrosine kinase activity.... Purdue Research Foundation

11/30/17 / #20170343481

Methods and systems for crack detection

Systems and methods suitable for capable of autonomous crack detection in surfaces by analyzing video of the surface. The systems and methods include the capability to produce a video of the surfaces, the capability to analyze individual frames of the video to obtain surface texture feature data for areas of... Purdue Research Foundation

11/30/17 / #20170343485

Retrieval of p-band soil reflectivity from signals of opportunity

A system and method for determining moisture content of soil, comprising providing bistatic radar configuration to measure soil reflectivity in UHF and S-band, cross-correlating between Sky-viewed and Earth-viewed signals and reflected signals in order to isolate the reflected signals, and correlating the isolated reflectesd signal to moisture content of the... Purdue Research Foundation

11/30/17 / #20170343526

Methods of analyzing crude oil

The invention generally relates to methods of analyzing crude oil. In certain embodiments, methods of the invention involve obtaining a crude oil sample, and subjecting the crude oil sample to mass spectrometry analysis. In certain embodiments, the method is performed without any sample pre-purification steps.... Purdue Research Foundation

11/30/17 / #20170343987

Microcontroller energy management system

A microcontroller system which employs an intermediate approach in hybrid FRAM-SRAM that involves memory mapping of program sections to retain the reliability benefits provided by FRAM while performing almost as efficiently as an SRAM-based system. They system utilizes an energy-aware memory mapping method which maps different program sections to the... Purdue Research Foundation

11/23/17 / #20170335477

Systems and methods for producing metal clusters; functionalized surfaces; and droplets including solvated metal ions

The invention generally relates to systems and methods for producing metal clusters; functionalized surfaces; and droplets including solvated metal ions. In certain aspects, the invention provides methods that involve providing a metal and a solvent. The methods additionally involve applying voltage to the solvated metal to thereby produce solvent droplets... Purdue Research Foundation

11/23/17 / #20170336431

System and measuring exhaust flow velocity of supersonic nozzles

A system for measuring supersonic nozzle exhaust flow, comprising a seeding module, an optics module configured to direct an optical signal from the supersonic nozzle, and a streak camera. The streak camera is optically connected to the optical signal, the streak camera configured to image the path of the seed... Purdue Research Foundation

11/16/17 / #20170326689

Methods of forming a substrate having an open pore therein and products formed thereby

Methods and products formed thereby that include depositing a light-absorbing particle on a substrate and irradiating the particle with a pulsed laser beam to cause an increase in local temperature of a portion of the substrate contacted by and adjacent to the particle, enabling the particle to penetrate and migrate... Purdue Research Foundation

11/16/17 / #20170330070

Spin orbit torque based electronic neuron

An electronic neuron device that includes a thresholding unit which utilizes current-induced spin-orbit torque (SOT). A two-step switching scheme is implemented with the device. In the first step, a charge current through heavy metal (HM) places the magnetization of a nano-magnet along the hard-axis (i.e. an unstable point for the... Purdue Research Foundation

11/16/17 / #20170331109

Methods of making electrodes, electrodes made therefrom, and electrochemical energy storage cells utilizing the electrodes

Method of making interconnected layered porous carbon sheets with porosity within the carbon sheets and in-between the carbon sheets for use as an electrode. Method of making a metal-nanoparticle carbon composite, wherein metal particles are surrounded by shells made of amorphous carbon. Electrodes containing an amorphous carbon structure comprising a... Purdue Research Foundation

11/09/17 / #20170319657

Method of treating a bladder cancer using a chimeric egf-targeted bacterial toxin

Provided is a method of treating a bladder cancer in an animal or human comprising: administering to an animal or human patient a therapeutic composition comprising a first fusion protein capable of specifically binding to an epidermal growth factor receptor (EGFR) on the surface of a cancer cell and comprising... Purdue Research Foundation

11/09/17 / #20170320164

Laser-assisted micromachining systems and methods

Laser-assisted micromachining methods and systems capable of providing flexible beam positioning and low incident angles. Such laser-assisted micromachining systems preferably include a laser beam source, a cutting tool, means for engaging a workpiece with the cutting tool, optical elements arranged to define a path of a laser beam emitted by... Purdue Research Foundation

11/09/17 / #20170320992

Poly(alkylene carbonate)-based amphiphilic block copolymers and methods of use thereof

This invention provides poly(alkylene carbonate)-based amphiphilic block copolymers, compositions comprising the same, e.g., micelles, and methods of use thereof. This invention further provides methods for preparing the poly(alkylene carbonate)-based amphiphilic block copolymers of the invention.... Purdue Research Foundation

11/02/17 / #20170311559

Moisture management & perennial crop sustainability decision system

Disclosed herein are a system and method that integrate vineyard sensor data into an environment that enables analysis, historical trend analytics, spatio-temporal analytics, and weather model fusion for improved decision making from vineyard management to wine production. The integration of new sensor data from multiple soil depths with surface measurements,... Purdue Research Foundation

11/02/17 / #20170312795

Systems with anti-fouling control and methods for controlling fouling within a channel of a plug flow crystallizer

The invention generally relates to systems with anti-fouling control and methods for controlling fouling within a channel of a plug flow crystallizer. In certain aspects, the invention provides a system that includes a plug flow crystallizer having a channel, one or more heating/cooling elements, each operably associated with a different... Purdue Research Foundation

11/02/17 / #20170313685

Broad-spectrum non-covalent coronavirus protease inhibitors

This invention pertains to materials and methods for the treatment of patients with coronavirus infection and the control of zoonotic disease outbreaks using broad-spectrum non-covalent coronavirus protease inhibitors.... Purdue Research Foundation

11/02/17 / #20170313738

Raman tag

The present invention provides novel Raman tags for exploring membrane interactions in cells. The tags comprise a phenyl diyne probe where in the dyine is capped with the phenyl group. Methods for using the tags are also provided.... Purdue Research Foundation

10/26/17 / #20170307533

Metal-antibody tagging and plasma-based detection

An apparatus and method for characterizing a target, e.g., microbial samples or biological toxins, includes labeling the target with a biomolecular recognition construct and measuring an atomic-spectra signal of the biomolecular recognition construct. The method can include heating the labeled target before measuring the atomic-spectra signal. The atomic-spectra signal can... Purdue Research Foundation

10/26/17 / #20170309462

Mass spectrometry analysis of microorganisms in samples

The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.... Purdue Research Foundation

10/19/17 / #20170296505

Long-chain carboxychromanols and analogs for use as anti-inflammatory agents

Long-chain carboxychromanol compounds useful for treating conditions associated with the need to inhibit cyclooxygenase-1, cyclooxygenase-2, and/or 5-lipoxygenase, and pharmaceutical formulations containing the compounds are provided herein.... Purdue Research Foundation

10/12/17 / #20170290900

Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics

Cytotoxic lymphocytes expressing chimeric antigen receptors (CAR) that target and bind small conjugate molecules (SCM) are disclosed, as well as methods of using the cells and the SCMs in the treatment of cancer.... Purdue Research Foundation

10/05/17 / #20170283852

Novel ubiquitination system and the uses thereof

An unprecedented mechanism of ubiquitination that is independent of E1 and E2 enzymes, instead relying on activation of ubiquitin by ADP-ribosylation, and which is mediated by members of the SidE effector family encoded by the bacterial pathogen Legionella pneumophila is disclosed. The herein disclosed method demonstrates a method in which... Purdue Research Foundation

10/05/17 / #20170284935

System and sensing and trapping nanoparticles with plasmonic nanopores

An apparatus for trapping and sensing nanoparticles using plasmonic nanopores, comprising a conductive transparent layer, a conductive film layer mounted to a substrate, the film layer comprising a plurality of nanopores for trapping nanoparticles contained in a fluid situated between the conductive transparent layer and the conductive film layer, and... Purdue Research Foundation

10/05/17 / #20170285262

Passive optical diode on semiconductor substrate

A method of fabricating an optical device includes forming on a semiconductor substrate a first optical cavity, a second optical cavity, a first light guide and a second light guide. The first light guide has an input, and is optically coupled to the first optical cavity by a first coupling... Purdue Research Foundation

10/05/17 / #20170286815

Generating an object map from a plurality of binary images

In an example, a method is described that includes dividing an input image into a plurality of strips, where each strip is smaller than a whole of the input image. A plurality of binary images is then generated, where each of the binary images corresponds to one of the strips.... Purdue Research Foundation

10/05/17 / #20170287690

Ion focusing

The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an... Purdue Research Foundation

Patent Packs
09/28/17 / #20170273256

Botanical air filtration system and method

A system and process for filtering air by removing pollutants from the air with living plants. The system includes an enclosure, a wall within the enclosure on which living plants are supported and grow in one or more horizontal plant beds defining vertical tiers along the wall, an irrigation system... Purdue Research Foundation

09/28/17 / #20170273605

Enclosed desorption electrospray ionization probes and use thereof

The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.... Purdue Research Foundation

09/28/17 / #20170273731

Novel technique for therapeutic contact lens systems

The invention relates to electronic contact lens systems, methods for fabrication thereof, and uses thereof for treatment of ophthalmic diseases and conditions, for example, meibomian gland dysfunction.... Purdue Research Foundation

09/28/17 / #20170275345

Collagen-binding synthetic peptidoglycans, preparation, and methods of use

This invention relates to collagen-binding synthetic peptidoglycans and engineered collagen matrices comprising a collagen matrix and a collagen-binding synthetic peptidoglycan where the collagen-binding synthetic peptidoglycan can be aberrant or can have amino acid homology with a portion of the amino acid sequence of a protein or a proteoglycan that regulates... Purdue Research Foundation

09/28/17 / #20170275713

Compositions and methods for treating leather

The present disclosure provides a composition for treating leather and similar materials. The composition comprises from about 40% (w/w) to about 60% (w/w) of an oil obtained from natural sources; from about 1% (w/w) to about 15% (w/w) of a wax obtained from natural sources; and from about 20% (w/w)... Purdue Research Foundation

09/28/17 / #20170279384

Motor control system and method

A motor control interface system, comprising an interface communication module configured to connect to a wired control port of a rotating electronically controlled motor, such as in an HVAC system, wherein the interface communication module converts a rotating motor speed signal to a wireless signal for receipt by an external... Purdue Research Foundation

09/28/17 / #20170280105

Pubic safety camera monitoring system and method

A system for determining a travel path, including a network of at least one camera, a communication hub coupled to the network of at least one camera, at least one electronic communication device, and a data processing system coupled to the communication hub, the data processing system comprising one or... Purdue Research Foundation

09/28/17 / #20170280106

Pubic safety camera identification and monitoring system and method

A system for determining a travel path, including a network of at least one camera, a communication hub coupled to the network of at least one camera, at least one electronic communication device, and a data processing system coupled to the communication hub, the data processing system comprising one or... Purdue Research Foundation

09/21/17 / #20170266303

Methods of treating cancer by targeting tumor-associated macrophages

Methods for treating cancers using one or more compounds comprising a folate receptor binding ligand attached to a drug via a linker are described. Methods for treating cancers using one or more compounds comprising a folate receptor binding ligand attached to a drug via a linker to target tumor associated... Purdue Research Foundation

09/21/17 / #20170266719

Hot-chamber die casting systems and methods

Hot-chamber die casting systems for casting aluminum, copper, titanium, and their alloys, as well as other high temperature and/or reactive metals. The hot-chamber die casting system comprises an injection system that includes a cylinder, a plunger reciprocable within the cylinder, and a gooseneck that defines a passage fluidically connected to... Purdue Research Foundation

09/21/17 / #20170267667

Alkenyldiarylmethanes as non-nucleoside reverse transcriptase inhibitors for anti-hiv-1 chemotherapy

The invention disclosed herein pertains to compounds of alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment of patients with acquired-immune deficiency syndrome (AIDS). Also described are methods for treating AIDS patients using the described alkenyldiarylmethane compounds.... Purdue Research Foundation

09/21/17 / #20170269300

Single photon source

The invention related to single photon emission systems based on nano-diamonds. Single-photon sources have a broad range of applications in quantum communication, quantum computing and quantum metrology.... Purdue Research Foundation

09/14/17 / #20170258923

Psma binding ligand-linker conjugates and methods for using

Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.... Purdue Research Foundation

09/14/17 / #20170262726

Tex line detection

A system and method for text line detection are described Examples include detection of symbols in an image received from an image-capturing device. In examples, for each of at least some of the symbols, neighboring symbols within a local region a given distance from the symbol are analyzed in order... Purdue Research Foundation

09/07/17 / #20170252459

Multivalent fibronectin-integrin binding compositions and methods of use thereof

The invention provides multivalent fibronectin-integrin binding compositions and methods of use thereof. In certain embodiments, the invention provides peptide compositions that include at least two fibronectin binding peptides coupled together as a cancer therapeutic or a diagnostic tool.... Purdue Research Foundation

Patent Packs
09/07/17 / #20170253962

Plasma-enhanced chemical vapor deposition methods for graphene deposition

A graphene deposition process. The process includes the steps of placing a substrate into a deposition chamber and heating the chamber, generating radio frequency plasma at a location proximate to the substrate while flowing a precursor gas containing carbon through the plasma and over the substrate.... Purdue Research Foundation

09/07/17 / #20170256406

Processes for shaping nanomaterials

Processes for shaping one- and two-dimensional nanomaterials, and thereby inducing local strains therein preferably to control one or more of their material properties. The processes include providing a substrate comprising a three-dimensional surface feature thereon, locating a nanomaterial on the substrate and over the surface feature, and directing a laser... Purdue Research Foundation

08/31/17 / #20170246314

Folate receptor binding conjugates of antifolates

Conjugates of antifolates, releasable linkers, and drugs, and pharmaceutical compositions containing them are described. The conjugates are useful for treating diseases arising from pathogenic cell populations. Methods for treating stroll diseases are also described.... Purdue Research Foundation

08/31/17 / #20170247555

Aqueous ink composition

Provided in one example herein is an aqueous ink composition, comprising: pigment particles comprising at least one metal oxide; an aqueous medium; and a cationic double-chain surfactant comprising a quaternary ammonium salt. Methods of making and using the ink composition are also provided.... Purdue Research Foundation

08/31/17 / #20170248607

Analyzing a metabolite level in a sample

The invention generally relates to methods for analyzing a metabolite level in a sample. In certain embodiments, methods of the invention may involve obtaining a sample, analyzing the sample using a mass spectrometry technique to determine a level of at least one metabolite in the sample, and correlating the metabolite... Purdue Research Foundation

08/31/17 / #20170248707

Compositions and methods for detecting radiation

Tensioned metastable fluid detectors are disclosed that minimize false positive detection events. The methods involve the use of new fluids that provide improved neutron-alpha fission detection at reduced tension states. The rate of spin is also increased using a new protocol that avoids the creation of liquid imbalances in the... Purdue Research Foundation

08/31/17 / #20170249550

Electronic synapse having spin-orbit torque induced spiketiming dependent plasticity

An electronic synapse is disclosed, comprising a heavy metal layer having a high spin orbit coupling, a domain wall magnet layer having a bottom surface adjacent to a top surface of the heavy metal layer, the domain wall magnet layer having a perpendicular magnetic anisotropy, the domain wall magnet layer... Purdue Research Foundation

08/24/17 / #20170238712

Chair, stool assembly, and system

A chair including structural members having hinge joints at ends thereof pivotally coupling each of the members to one or more adjoining members. The chair is configured to be arranged in a collapsed configuration wherein all of the members are in the same plane and define a substantially planar shape,... Purdue Research Foundation

08/24/17 / #20170240484

Solid-rocket propellants

Solid-fuel rocket propellants comprising an oxidizer, an oxophilic metal-halophilic metal formulation, and a binder are described herein. Further described are processes for preparing such propellants and methods of reducing hydrogen chloride production via the combustion of such propellants. Non-limiting examples of such formulations include aluminum-lithium alloys.... Purdue Research Foundation

08/24/17 / #20170243672

Composite transparent conducting films and methods for production thereof

A composite transparent conducting film (TCF) on a substrate that includes a first region extending to a first depth of the TCF and having a higher density (lower porosity) than a second region of the TCF located at a different depth of the TCF. A method of forming the composite... Purdue Research Foundation

08/17/17 / #20170231853

Device and methods for movement assistance

Assistive movement devices and methods therefor are provided that are capable of redirecting loads from an individual's foot to hip when an individual is recovering from an injury at or below the knee. The devices include a frame assembly comprising an upper member, a lower member, and a joint therebetween.... Purdue Research Foundation

08/17/17 / #20170232119

Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors

The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods... Purdue Research Foundation

08/17/17 / #20170232611

Educational systems comprising programmable controllers and methods of teaching therewith

Systems and methods for hands-on training of students. Such a system includes one or more programmable controllers configured to interact with one or more external devices. Each programmable controller includes a microcontroller, a memory device, an interface for remotely accessing the programmable controller, and at least one bus interface for... Purdue Research Foundation

08/17/17 / #20170235021

Methods of forming particulate films and films and devices made therefrom

A method of depositing a film comprising a monolayer of particles. The method includes providing a dispersion comprising particles and at least two liquids and depositing drops of the dispersion onto a substrate and evaporating the at least two liquids resulting in a film of a monolayer of the particles.... Purdue Research Foundation

08/17/17 / #20170235162

Time-varying metasurface structure

A time-varying optical metasurface, comprising a plurality of modulated nano-antennas configured to vary dynamically over time. The metasurface may be implemented as part of an optical isolator, wherein the time-varying metasurface provides uni-directional light flow. The metasurface allows the breakage of Lorentz reciprocity in time-reversal. The metasurface may operate in... Purdue Research Foundation

08/10/17 / #20170223943

Automatic monitoring of insect populations

Illustrative embodiments of integrated pest management (IPM) systems and electronic insect monitoring devices (EIMDs) are disclosed. In some embodiments, the EIMDs may each comprise a lure for attracting at least one target insect species, one or more sensors configured to generate one or more output signals in response to an... Purdue Research Foundation

08/10/17 / #20170230360

Continuous authentication system and method based on bioaura

A user authentication system for an electronic device for use with a plurality of wireless wearable medical sensors (WMSs) and a wireless base station that receives a biomedical data stream (biostream) from each WMS. The system includes a BioAura engine located on a server, the server has a wireless transmitter/receiver... Purdue Research Foundation

08/03/17 / #20170216465

Design and development of neurokinin-1 receptor-binding agent delivery conjugates

Neurokinin-1 (NK-1) receptor-binding agent delivery conjugates, compositions comprising NK-1 receptor-binding agent delivery conjugates, and methods for making and administering NK-1 receptor-binding agent delivery conjugates are provided. A conjugate may include an NK-1 receptor-binding moiety, a linker group containing at least one linker selected from the group of a releasable linker... Purdue Research Foundation

08/03/17 / #20170217996

Large-scale diastereoselective syntheses of cycloheptadienylsulfones and stereotetrads

The invention relates to processes for large-scale diastereoselective syntheses of cycloheptadienylsulfone and stereotetrads, key intermediates for the preparation of Aplyronine A.... Purdue Research Foundation

08/03/17 / #20170219485

Organism identification

A system for the identification of micro-organisms includes an irradiation unit adapted to sequentially provide coherent electromagnetic radiation of one or more wavelengths along a common optical path. A holder is adapted to retain a substrate having a surface adapted for growth of a micro-organism colony. A beamsplitter is adapted... Purdue Research Foundation

08/03/17 / #20170221695

Systems and methods for ejection of ions from an ion trap

The invention generally relates to systems and methods for ejection of ions from an ion trap. In certain embodiments, systems and methods of the invention sum two different frequency signals into a single summed signal that is applied to an ion trap. In other embodiments, an amplitude of a single... Purdue Research Foundation








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