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Purdue Research Foundation patents


Recent patent applications related to Purdue Research Foundation. Purdue Research Foundation is listed as an Agent/Assignee. Note: Purdue Research Foundation may have other listings under different names/spellings. We're not affiliated with Purdue Research Foundation, we're just tracking patents.

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Sketch-based 3d modeling system

A sketch-based 3d modeling system, comprising a computer processing unit, a digital memory, and an electronic display, the computer processing unit and the digital memory configured to receive a silhouette of an object from a hand-held user input device using a touch-screen display, automatically fill in the region between the silhouette with a 3d mesh, wherein the mesh approximates a geometry of the object, and display the object on the touch-screen display.. . ... Purdue Research Foundation

Ligand ionophore conjugates

The invention described herein pertains to ligand-ionophore conjugates, that may also comprise a linked therapeutic agent or imaging agent, and pharmaceutical compositions containing the conjugates. Also described are methods of using the conjugates for increasing the endosomal accumulation and escape of a therapeutic agent, or an imaging agent.. ... Purdue Research Foundation

Polymer lung surfactants

Disclosed herein are fully synthetic polymer-based lung surfactant materials, for the first time, as next generation srt. In vitro studies on these polymer lung surfactants show that the candidate materials effectively mimic the surface tension controlling properties of currently marketed natural lung surfactants. ... Purdue Research Foundation

Composites material with suspended particles and method of using the same

An intermediate composite capable of transferring a biological or chemical material to be patterned on a surface. The intermediate composite includes a hydrogel, and particles suspended in the hydrogel, generating a particle-gel composite (composite), the composite is configured to absorb a biological or chemical material (agent), and further configured to deposit the agent when the composite is positioned proximate to a surface on which the agent is to be deposited.. ... Purdue Research Foundation

Composites material with suspended particles and method of using the same

An intermediate composite capable of transferring a biological or chemical material to be patterned on a surface. The intermediate composite includes a hydrogel, and particles suspended in the hydrogel, generating a particle-gel composite (composite), the composite is configured to absorb a biological or chemical material (agent), and further configured to deposit the agent when the composite is positioned proximate to a surface on which the agent is to be deposited.. ... Purdue Research Foundation

Liquefaction of cellulose-containing feedstocks

A method for producing a pumpable slurry from a cellulose-containing feedstock is presented herein.. . ... Purdue Research Foundation

Cell-collagen-silica composites and methods of making and using the same

Soluble, self-assembling collagens derived from tissues are extensively characterized such that one can predict and customize the final collagen-fibril matrix with respect to fibril microstructure (i.e., fibril density, interfibril branching), viscoelasticity and proteolytic degradability. As shown herein these matrices template and direct the deposition of mesoporous silica at the level of individual collagen fibrils. ... Purdue Research Foundation

Systems and methods for performing a surgical procedure

Systems and methods for performing surgical procedures. Such a system includes a cannula having a tubular body and a distal end is sized and configured to be inserted into a body cavity. ... Purdue Research Foundation

Culture imaging system

A system for the characterization of a colony of microorganisms includes a coherent light source configured to provide coherent light of one or more wavelengths along a common optical path. A holder is configured to operationally arrange a substrate so that the colony of microorganisms on a surface of the substrate is positioned to receive the coherent light. ... Purdue Research Foundation

High emissivity materials and methods of manufacture

A hypersonic refractory material, including a refractory leading edge portion for a hypersonic vehicle and a high emissivity oxide coating adhered to the refractory leading edge portion. The high emissivity oxide coating is zrb2 doped with a cation dopant material selected from the group including sm, tm, and mixtures thereof. ... Purdue Research Foundation

Chlorination-uv process for decomposition and detoxification of microcystin-lr

Provided is an ordered step-wise method for the chlorination and photodestruction of mc-lr contamination of an aqueous liquid such as a potable water supply infested with blue-green algae (cyanobacteria). It has been found possible to usefully chlorinate the water at lower chlorine:mc-lr ratios as compared to known methods and then to irradiate the water with ultraviolet radiation to photolyze the chlorinated mc-lr. ... Purdue Research Foundation

Lower leg prosthetic systems and devices

Systems and devices for use as lower leg prosthetic devices that include a foot portion having anterior and posterior ends and a first surface having a protrusion that protrudes therefrom adjacent the posterior end of the foot portion, has a semispherical or hemispherical surface with a passage therethrough extending laterally relative to the foot portion. The systems and devices further include a toe portion pivotally coupled to the anterior end of the foot portion, and a plate portion configured to couple to an attachment device and thereby be functionally secured to a user. ... Purdue Research Foundation

Collaborative 3d modeling system

A collaborative 3d modeling system, comprising a computer processing unit, a digital memory, and an electronic display, the computer processing unit and the digital memory configured to provide 3d model representations of a first plurality of versions of an object component for a first user, the versions being selectable along a first axis, and using the electronic display, provide a plurality of user identifications which are selectable along a second axis, wherein selecting a subsequent user causes a second plurality of said versions of said object component to be displayed on the electronic display.. . ... Purdue Research Foundation

Physical modeling of electronic devices/systems

A method for modeling a material at least partially-defined by atomic information includes, for each of a plurality of configurations of the material, determining energy moments for a density of states of the respective configuration of the material, and generating a tight binding hamiltonian matrix for the respective configuration of the material. The method further includes, for each of the plurality of configurations of the material, forming a tight binding model of the configuration of the material by resolving a linking of (i) the energy moments for the density of states of the material to (ii) the tight binding hamiltonian matrix for the material. ... Purdue Research Foundation

05/03/18 / #20180119957

Apparatus and methods of operating a combustion engine

The present invention generally relates to dual chamber combustion engines. The invention particularly relates to apparatus and methods for ignition of ultra-lean fuel/air mixtures with fuel/air mixture streams traveling at supersonic velocities. ... Purdue Research Foundation

05/03/18 / #20180117797

Methods of making hydrophobic contoured surfaces and hydrophobic contoured surfaces and devices made therefrom

A method of creating a polymer surface with surface structures is disclosed. The method includes creating a mold, forming a metal sheet into the molds, creating a surface structure on a surface of the metal sheet by exposing the surface to laser pulses, and bringing a curable polymer to be in contact with the surface of the metal sheet containing the surface structure, curing the curable polymer, and separating the cured polymer from the metal sheet, resulting in a polymer surface containing the surface structure. ... Purdue Research Foundation

05/03/18 / #20180117196

Plasma systems driven by dc voltage and methods of using the same

A plasma generating system capable of generating a cold plasma. The plasma generating includes two electrodes, a dc voltage source capable of applying a constant dc voltage between the two electrodes, an insulator located in proximity of the two electrodes, and a gas filling a gap between the two electrodes, wherein cold plasma in the form of series of repetitive streamer breakdowns of the gas is generated, in response to the constant dc voltage applied between the two electrodes. ... Purdue Research Foundation

04/19/18 / #20180108798

Distributed photodiode with built-in equalization

A distributed photodiode with fir filtering function enabled by a lumped transmission line is provided. The distributed photodiode includes inductors, a plurality of photodiode segments, photodiode biasing components, and termination impedance. ... Purdue Research Foundation

04/19/18 / #20180107620

Computing architecture with concurrent programmable data co-processor

A coprocessor (pl) is disclosed. The pl includes a memory router, at least one collection block that is configured to transfer data to/from the memory router, each collection block includes a collection router that is configured to i) transfer data to/from the memory router, ii) transfer data to/from at least one collection router of a neighboring collection block, and iii) transfer data to/from blocks within the collection block, and at least one programmable operator that is configured to i) transfer data to/from the collection router, and ii) perform a programmable operation on data received from the collection router.. ... Purdue Research Foundation

04/19/18 / #20180104946

Methods for forming optically heterogeneous phantom structures and phantom structures formed thereby

An optically heterogeneous phantom structure for use in optical imaging techniques. The phantom structure includes an external shape simulating an object to be subjected to an optical imaging technique, the external shape defining an external surface that encloses an internal volume of the external shape; and an optically heterogeneous material filling the internal volume and having heterogeneous optical properties for simulating at least one optical parameter of at least one region within the object. ... Purdue Research Foundation

04/19/18 / #20180104936

Electroactive polymers, methods of manufacture, and structures formed thereof

Methods for producing layered structures that include a conductive polymeric layer and a dielectric polymeric layer. The dielectric polymeric layer can be formed by curing a first volume of a dielectric polymeric material. ... Purdue Research Foundation

04/12/18 / #20180102242

Systems and methods for ambient surface cleaning and sampling with mass spectrometric analysis

The invention generally relates to systems and methods for continuous or batch wise sampling of a surface for analysis of trace chemical constituents that may be present on the surface by mass spectrometry. Integration of time and place of the sampling and analysis processes allows real-time on-the-spot response to the analytical data and can take into account that material is not necessarily uniformly distributed on a surface. ... Purdue Research Foundation

04/12/18 / #20180102200

Laser-based fabrication of carbon nanotube-metal composites on flexible substrates

The present disclosure relates to a novel method of laser-based fabrication of a carbon nanotube (cnt)-metal composite on a flexible substrate, and the fabricated cnt-metal composite that is bonded with the flexible substrate, and that has a high electrical conductivity, and that has a longer bending-fatigue life than the laser-sintered metal of the same type without cnts onto the flexible substrate.. . ... Purdue Research Foundation

03/29/18 / #20180089804

Method of processing an image

A non-transitory computer-readable medium encoded with a computer-readable program, which when executed by a processor, will cause a computer to execute a computational method, the computational method including collecting an image data, wherein the collecting the image data comprises collecting a first plurality of rgb images and a second plurality of hyperspectral images. The method further includes orthorectifying the image data to produce an rgb based orthophoto and a partially rectified hyperspectral orthophoto. ... Purdue Research Foundation

03/29/18 / #20180089006

Interactive, constraint-network prognostics and diagnostics to control errors and conflicts (ipdn)

Methods for interactively preventing and detecting conflicts and errors (ces) through prognostics and diagnostics. Centralized and decentralized conflict and error prevention and detection (cepd) logic is developed for prognostics and diagnostics over three types of real-world constraint networks: random networks (rn), scale-free networks (sfn), and bose-einstein condensation networks (becn). ... Purdue Research Foundation

03/29/18 / #20180088041

Depth-resolved mid-infrared photothermal imaging of living cells and organisms with sub-mciron spatial resolution

Systems and methods for sensing vibrational absorption induced photothermal effect via a visible light source. A mid-infrared photothermal probe (mi-ptp, or mip) approach achieves 10 mm detection sensitivity and sub-micron lateral spatial resolution. ... Purdue Research Foundation

03/22/18 / #20180083683

Apparatus and method for feedback of channel state information in wireless communication system

The present disclosure relates to a pre-5th-generation (5g) or 5g communication system to be provided for supporting higher data rates beyond 4th-generation (4g) communication system such as long term evolution (lte). A feedback transmission method for a receiving device in a multiple input multiple output system according to one embodiment comprises: a step of measuring channel state information; a first quantization step of quantizing the channel state information using a first codebook; a second quantization step of quantizing the channel state information using second and third codebooks which are different from the first codebook; and a step of feeding back the channel state information on the basis of a selection result of one of the first and second quantization steps.. ... Purdue Research Foundation

03/22/18 / #20180083414

Mode-locked and wavelength tunable optical frequency comb generation through dynamic control of microresonators

A tunable optical comb generator having a source laser configured to generate a continuous wave (cw) light at a first wavelength; and a microresonator coupled to the source laser and configured to receive the cw light and generate an optical signal having a plurality of output wavelengths corresponding to the first wavelength. The generator includes a microresonator tuning device coupled to the microresonator and configured to tune the microresonator to compensate the microresonator for wavelength shifts. ... Purdue Research Foundation

03/22/18 / #20180083258

Rechargeable battery electrodes having optimized particle morphology

A battery, comprising an anode and a cathode, the cathode comprising particles having an aspect ratio between 0.09 and 0.5. In certain embodiments, the particles are ellipsoidal. ... Purdue Research Foundation

03/22/18 / #20180079697

Solid-rocket propellants

Solid-fuel rocket propellants comprising an oxidizer, an oxophilic metal-halophilic metal formulation, and a binder are described herein. Further described are processes for preparing such propellants and methods of reducing hydrogen chloride production via the combustion of such propellants. ... Purdue Research Foundation

03/22/18 / #20180078552

Methods for treating hemolytic diseases and sickle cell disease

The present disclosure generally relates to methods of treating hemolytic diseases such as sickle cell anemia using kinase inhibitors, for example, compounds that inhibit the spleen tyrosine kinase (syk). In some embodiments a method is presented to prevent thrombosis in blood vessels of patients with a hemolytic disease comprising the step of: administrating to a patient having at least one hemolytic disease a therapeutically effective amount of at least one syk inhibitor. ... Purdue Research Foundation

03/15/18 / #20180076403

Amine-boranes as organic ligands for surface functionalization

The present invention relates to a process for functionalizing a surface of semi-conductors, conductors, and dielectrics using an amine-borane bearing a functionality from a group of, but not limited to, alkene, alkyne, hydroxyl, thiol, acetal, ester, amide, nitrile, nitro, or alkoxysilane, under a mild condition. Products of this facile process are also in the scope of this disclosure.. ... Purdue Research Foundation

03/15/18 / #20180074005

Hydraulic hoses with life-sensing capability and methods therefor

A system and methods for predicting structural failure of at least a portion of a wall of a fluid containment vessel. The wall has an innermost layer for contact with a fluid contained by the vessel and an outermost layer parallel with the innermost layer. ... Purdue Research Foundation

03/08/18 / #20180069536

Electronic comparison systems

An electronic comparison system includes input stages that successively provide bits of code words. One-shots connected to respective stages successively provide a first bit value until receiving a bit having a non-preferred value concurrently with an enable signal, and then provide a second, different bit value. ... Purdue Research Foundation

03/08/18 / #20180068090

System and method of extending the linear dynamic range of event counting

A method and apparatus for photon, ion or particle counting described that provides seven orders of magnitude of linear dynamic range (ldr) for a single detector. By explicitly considering the log-normal probability distribution in voltage transients as a function of the number of photons, ions or particles present, the binomial distribution of observed counts for a given threshold, the mean number of photons, ions or particles can be determined well beyond the conventional limit.. ... Purdue Research Foundation

03/08/18 / #20180067103

Blood brain barrier models and methods to generate and use the same

The present disclosure generally relates to a process to prepare a cell culture system that mimics the structure of blood brain barrier (bbb) and are useful to study the functions thereof. In particular, the present invention relates to a direct-contact coculture and triculture systems prepared by plating bmecs on a pre-formed lawn of coculture of astrocytes and pericytes on the apical surface of a culture-chamber to achieve a truly direct contact triculture model for bbb. ... Purdue Research Foundation

03/08/18 / #20180066977

System for weighing individual micro- and nano- sized particles

A device for weighing micro- and nano-sized particles. The device includes a base portion, an oscillator coupled to the base portion configured to vibrate the base portion, a first cantilevered beam coupled to the base portion at a proximal end and having a tip portion at a distal end, and a second cantilevered beam coupled to the base portion at a proximal end and having a tip portion at a distal end, each of the first and second cantilever beams further having a first plurality of fingers near the first tip portion inwardly pointing and a second plurality of fingers near the second tip portion inwardly pointing, respectively, such that the entirety of each cantilever beam is positioned in a side-by-side manner next to the entirety of the other forming substantially mirror images of one another, the first plurality of fingers interdigitating with the second plurality of fingers such that the first cantilevered beam and the second cantilevered beam can oscillate independent of each other, the interdigitating fingers separated by gaps that are configured to reflect light from the interdigitating fingers during oscillation of the first and second cantilevered beams to form a diffraction pattern.. ... Purdue Research Foundation

03/08/18 / #20180066976

Method for weighing individual micro- and nano- sized particles

A method for measuring mass of a micro- and nano-sized particle. The method includes placing the micro- or nano-sized particle on a resonator having an oscillator and a first and second cantilevered arms with interdigitating finger, energizing the oscillator at a selective frequency thereby causing mechanical vibration in the first and second cantilevered arms, directing a light beam from a light source onto the interdigitating fingers, sensing intensity of light of the reflected diffraction pattern by at least one photodetector positioned about at least one of the modes, varying the frequency by sweeping a range of frequencies and correlating the sensed intensity to mass to thereby determine the mass of the micro- or nano-sized particle.. ... Purdue Research Foundation

03/08/18 / #20180064539

System and method of attaching soft tissue to an implant

One embodiment of the present invention is directed to compositions and methods for enhancing attachment of soft tissues to a metal prosthetic device. In one embodiment a construct is provided comprising a metal implant having a porous metal region, wherein said porous region exhibits a nano-textured surface.. ... Purdue Research Foundation

03/08/18 / #20180064370

Gait pattern analysis for predicting falls

A method for acquiring gait parameters of an individual is disclosed. The method includes capturing calibration images from foot marker placed on feet or shoes of an individual while an individual is standing still, the calibration images are obtained from a camera worn by the individual, capturing subsequent time-varying images from the foot markers while the individual is walking, and comparing the calibration images to the subsequent time-varying images by a processing unit that is coupled to the camera to determine changes between the initial relative image size of the foot markers and the time-varying images of the foot markers as a function of time to analyze gait of the individual.. ... Purdue Research Foundation

03/01/18 / #20180062130

Impact resistant battery enclosure systems

Battery enclosure arrangements for a vehicular battery system. The arrangements, capable of impact resistance include plurality of battery cells and a plurality of kinetic energy absorbing elements. ... Purdue Research Foundation

03/01/18 / #20180061620

Zero voltage mass spectrometry probes and systems

The invention generally relates to zero volt mass spectrometry probes and systems. In certain embodiments, the invention provides a system including a mass spectrometry probe including a porous material, and a mass spectrometer (bench-top or miniature mass spectrometer). ... Purdue Research Foundation

03/01/18 / #20180059039

Sensors and methods of identifying a gas, and levitated spin-optomechanical systems

Sensors and methods are provided that include a diamond material containing a nitrogen vacancy center, the diamond material being configured to be exposed to an environment comprising one or more gases, an optical light source configured to excite the nitrogen vacancy center of the diamond material with an optical light beam produced therefrom, a detector configured to detect a signal originating from the diamond material in response to the optical light beam exciting the nitrogen vacancy center, and the capability of analyzing the signal to identify a specific gas in the environment. Also included are levitated spin-optomechanical systems capable of elevating in a vacuum a diamond material containing a nitrogen vacancy center, applying microwave radiation to the diamond material for controlling and flipping the electron spin of the nitrogen vacancy center, and monitoring electron spin of the nitrogen vacancy center.. ... Purdue Research Foundation

03/01/18 / #20180057364

Processes for producing materials having a zeolite-type framework with heteroatoms incorporated therein

A process of producing a zeotype material having a zeolite-type framework. The process includes providing a zeolite having a framework, dealuminating the zeolite to remove aluminum atoms therefrom to produce a dealuminated framework comprising a plurality of vacancy sites, contacting the dealuminated framework with dichloromethane and a precursor comprising heteroatoms, and then heating the dealuminated framework, the dichloromethane, and the precursor under reflux conditions to incorporate the heteroatoms into at least some of the plurality of vacancy sites in the dealuminated framework to produce a zeotype material having a zeolite-type framework comprising the heteroatoms. ... Purdue Research Foundation

02/22/18 / #20180052103

Methods for second harmonic generation imaging of protein crystals

Methods for determining the 3-d structures of proteins. Such a method includes incorporating a compound into a protein crystal such that the compound enhances the activity of the protein crystal to second harmonic generation, illuminating the protein crystal with a sufficiently intense light to cause second harmonic generation by the protein crystal, and detecting a second harmonic generation response produced by the protein crystal that is suitable for protein structure determination by diffraction analysis.. ... Purdue Research Foundation

02/22/18 / #20180051040

Amine-boranes bearing borane-intolerant functionalities

Disclosed herein is the preparation of functional group containing amine-boranes from the corresponding amines. The mild reaction conditions allow for the direct preparation of several hitherto inaccessible amine-boranes containing a functional moiety, such as but not limited to, alkene, alkyne, hydroxyl, thiol, acetal, ester, amide, nitrile, nitro, and alkoxysilane.. ... Purdue Research Foundation

02/22/18 / #20180050972

Open-flask hydroboration and the use thereof

The present disclosure generally relates to a process for hydroboration of an alkene or alkyne using ammonia borane (ab). In particular, the present invention relates to hydroboration of an alkene or alkyne in the presence of air or moisture, and a clean process for facile preparation of an alcohol by oxidizing the organoborane so formed with hydrogen peroxide. ... Purdue Research Foundation

02/15/18 / #20180047552

Reaction monitoring

The invention generally relates to systems and methods for on-line reaction monitoring. In certain embodiments, the invention provides systems that include a reaction vessel having an outlet, a quantitation unit coupled to the outlet and configured to introduce internal standard and solvent into reaction solution flowed from the reaction vessel, one or more ion generating devices that receive flow from the quantitation unit, and a mass spectrometer. ... Purdue Research Foundation

02/15/18 / #20180045939

High frame-rate multichannel beam-scanning microscopy

A beam-scanning optical design is described for achieving up to khz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier of the mirror periods. ... Purdue Research Foundation

02/15/18 / #20180045606

Belt and pulley systems and methods of detecting belt damage

A system and method capable of detecting damage in a belt before catastrophic failure of the belt occurs. The system includes a belt having at least a first conductive component and/or at least a first dielectric component, and one or more pulleys to which the belt is mounted. ... Purdue Research Foundation

02/15/18 / #20180044469

Adhesives from renewable feedstocks

Disclosed herein is a novel copolymer: poly [(3,4-dihydroxymandelic acid)-co-(lactic acid)]. This novel copolymer can be produced from renewable feedstocks, possesses tunable degradation, and can achieve adhesion strengths rivaling the performance of existing glues and adhesives. ... Purdue Research Foundation

02/15/18 / #20180043327

Systems and methods for increasing reaction yield

The invention generally relates to systems and methods for increasing reaction yield. In certain embodiments, the invention provides systems for increasing a yield of a chemical reaction that include a pneumatic sprayer configured to generate a liquid spray discharge from a solvent. ... Purdue Research Foundation

02/15/18 / #20180043168

Vibration-based secure side channel for medical devices

According to some embodiments, a system for securing communications between an implantable wearable medical device (iwmd) and an external device (ed) is disclosed. The system includes a wireless radio frequency (rf) channel configured for communication between the iwmd and the ed. ... Purdue Research Foundation

02/08/18 / #20180040464

Systems and methods for relay ionization

The invention generally relates to systems and methods for relay ionization of a sample. In certain aspects, the invention provides systems that include an ion source that generates ions, a sample emitter configured to hold a sample, and a mass spectrometer. ... Purdue Research Foundation

02/01/18 / #20180033603

Sample analysis systems and methods of use thereof

The invention generally relates to sample analysis systems and methods of use thereof. In certain aspects, the invention provides a system for analyzing a sample that includes an ion generator configured to generate ions from a sample. ... Purdue Research Foundation

02/01/18 / #20180030550

Genetic locus associated with phytophthora root and stem rot in soybean

The present subject matter relates to methods and compositions for identifying soybean plants that having increased phytophthora root and stem rot resistance. The methods use molecular markers to identify and to select plants with increased phytophthora root and stem rot resistance or to identify and deselect plants with decreased phytophthora root and stem rot resistance. ... Purdue Research Foundation

02/01/18 / #20180030294

Ink and method of conducting an examination

An ink and method of conducting an examination suitable for reducing the likelihood that the students' answers on paper-based examinations may be changed at a later time prior to being graded. The ink includes a solution of marking particles, a suspension material, and a preserving material. ... Purdue Research Foundation

02/01/18 / #20180030091

Collagen-binding synthetic peptidoglycans for use in vascular intervention

This invention relates to collagen-binding synthetic peptidoglycans. More particularly, this invention relates to collagen-binding synthetic peptidoglycans for use in vascular intervention procedures. ... Purdue Research Foundation

02/01/18 / #20180029290

Methods and systems for fabricating elastomer-based electronic devices and devices formed thereby

Methods and systems suitable for fabricating multi-layer elastic electronic devices, and elastic electronic devices formed thereby. A method of fabricating an elastomer-based electronic device includes printing a first liquid material and then a second liquid material on a fabric substrate that comprises fibers. ... Purdue Research Foundation

01/25/18 / #20180026132

Methods of reducing the electrical and thermal resistance of sic substrates and devices made thereby

A power semiconductor device includes a silicon carbide substrate and at least a first layer or region formed above the substrate. The silicon carbide substrate has a pattern of pits formed thereon. ... Purdue Research Foundation

01/25/18 / #20180024108

Systems and methods for screening a sample based on multiple reaction monitoring mass spectrometry

The invention generally relates to systems methods for screening a sample based on multiple reaction monitoring mass spectrometry. In certain embodiments, the invention provides methods for screening a sample that involve ionizing a sample. ... Purdue Research Foundation

01/25/18 / #20180023107

Methods for mitigating the inhibitory effects of lignin and soluble phenolics for enzymatic conversion of cellulose

Disclosed herein are methods for improving ethanol production from biomass sources by blocking cellulose from binding to lignin.. . ... Purdue Research Foundation

01/25/18 / #20180022663

Reactive burning rate accelerators, solid energetic materials comprising the same, and methods of using the same

A reactive burning rate accelerator is provided that is configured to be at least partially embedded in a solid energetic material and comprises at least one metallic component and at least one non-metallic component. The reactive burning rate accelerator is configured to ignite and combust to increase the mass burning rate of the solid energetic material. ... Purdue Research Foundation

01/18/18 / #20180019320

Inp-based transistor fabrication

Methods of forming structures that include inp-based materials, such as a transistor operating as an inversion-type, enhancement-mode device are disclosed. A dielectric layer may be deposited by ald over a semiconductor layer including in and p. ... Purdue Research Foundation

01/18/18 / #20180019273

Energy harvesting configurable image sensor

An image sensor is provided, comprising a plurality of photo-diode pixels arranged in a two-dimensional array, an energy harvesting output bus connected to the pixels, an image sensing output bus connected to the pixels, and a plurality of switching busses, the switching buses connected to the pixels to direct output of a varying percentage of the pixels to either the energy harvesting output bus or the sensing bus.. . ... Purdue Research Foundation

01/18/18 / #20180018537

Non-spectroscopic imaging of plants

Monitoring stress symptoms in plants is crucial to maximize crop productivity. Nondestructive imaging of physiological changes in plants has been intensively used as invaluable tools in the agricultural industry. ... Purdue Research Foundation

01/18/18 / #20180017535

Ion generation using modified wetted porous materials

The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. ... Purdue Research Foundation

01/18/18 / #20180015661

Continuous and scalable 3d nanoprinting

A rapidly printing 3d nanostructures arrangement, comprising a first photonic source configured to provide photoinitiation energy to a polymer medium via a dynamic light spatial modulator to an excited state to initiate polymerization, a second photonic source configured to selectively provide inhibition energy to the polymerized medium to a depleted state to inhibit polymerization thereby generating a dead zone below a growth zone, the dead zone allows continuous 3d polymerization.. . ... Purdue Research Foundation

01/18/18 / #20180014744

Motor-activated multi-functional wrist orthotic

A multifunctional wrist orthotic comprising an electromyography (emg) sensor having at least two electrodes for attachment to a wrist of a user, an intertial measurement sensor (imu), a microcontroller unit (e.g., a arduino® mini) connected to the imu, a power supply unit. The microcontroller unit is configured to perform two-tiered gesture recognition, with the first tier comprising a fine gesture sensed by the emg sensor and the second tier comprising a gross gesture sensed by the imu sensor.. ... Purdue Research Foundation

01/11/18 / #20180013929

Color table compression

In some examples, a print cartridge includes a memory device comprising quantized coefficients derived from a lossy compression, at a selected step size, of a difference color table including a plurality of difference nodes in which each difference node represents a difference value that is a difference of a value of a node of a color table and a value of a corresponding node of a reference table, the quantized coefficients useable to produce a reconstructed difference color table including a first set of difference nodes each representing a difference value that is within an error threshold at the selected step size, and a second set of difference nodes each representing a difference value that is outside an error threshold at the selected step size. The memory device further comprises corrective information to correct the second set of difference nodes of the reconstructed difference color table.. ... Purdue Research Foundation

01/11/18 / #20180013928

Printing device supply component

In some examples, a supply component for a printing device includes a memory device comprising a plurality of corrective data to produce a corresponding plurality of color tables each customized for a respective media type of a plurality of media types, wherein a respective corrective data of the plurality of corrective data corresponds to nodes of a reference color table for the printing device that is able to accept the plurality of media types for printing. The respective corrective data includes a plurality of residual values to transform the nodes of the reference color table to a customized color table for use with a selected media type of the plurality of media types.. ... Purdue Research Foundation

01/11/18 / #20180013925

Color table compression

In some examples, a print cartridge includes a memory device comprising quantized coefficients derived from a compression of a difference table including a plurality of difference nodes in which each difference node represents a value that is a difference of a value of a node of a color table and a value of a corresponding node of a reference table, the quantized coefficients useable to produce a reconstructed difference table, and a plurality of residue nodes in which each residue node represents a value that is a difference of a value of a node of the color table and a value of a corresponding node of the reconstructed difference table.. . ... Purdue Research Foundation

01/11/18 / #20180013367

Hybrid surface magnet machine

A hybrid electrical machine containing surface mounted magnets which includes a magnetically permeable cylindrically shaped stator assembly having at least one stator winding formed about a plurality of stator teeth, a rotor assembly concentrically disposed within the stator assembly, including a magnetically permeable rotor backiron, a rotational drive mechanism coupled to the rotor backiron, and a plurality of protruding rotor poles, each including a magnetically permeable pole support assembly, a winding provided around the pole support assembly, and a radially magnetized permanent magnet assembly disposed about the pole support assembly.. . ... Purdue Research Foundation

01/11/18 / #20180012972

Nems devices with series ferroelectric negative capacitor

An electrical circuit comprising at least two negative capacitance insulators connected in series, one of the two negative capacitance insulators is biased to generate a negative capacitance. One of the negative capacitance insulators may include an air-gap which is part of a nanoelectromechnical system (nems) device and the second negative capacitance insulator includes a ferroelectric material. ... Purdue Research Foundation

01/11/18 / #20180012746

Probes, systems, cartridges, and methods of use thereof

The invention generally relates to probes, systems, cartridges, and methods of use thereof. In certain embodiments, the invention provides a probe including a porous material and a hollow member coupled to a distal portion of the porous material.. ... Purdue Research Foundation

01/11/18 / #20180008733

Non-toxic formulations of radio-luminescent nanoparticles for use as cancer radio-sensitizing agents

The invention relates generally to a formulation in which metal tungstate or metal molybdate particles are encapsulated within biocompatible, diseased cell-targeting polymeric coatings. Such formulations render metal tungstate or metal molybdate particles suitable for in vivo biomedical imaging and therapeutic applications.. ... Purdue Research Foundation

01/04/18 / #20180003865

Plasmonic metal nitride and transparent conductive oxide nanostructures for plasmon assisted catalysis

A nanostructured material system for efficient collection of photo-excited carriers is provided. They system comprises a plurality of plasmonic metal nitride core material elements coupled to a plurality of semiconductor material elements. ... Purdue Research Foundation

12/28/17 / #20170368644

Transient liquid phase bonding process and assemblies formed thereby

Processes of joining substrates via transient liquid phase bonding (tlpb). The processes include providing an interlayer of a low melting temperature phase (ltp) that includes sn and bi between and in contact with at least two substrates, and heating the substrates and the interlayer therebetween at a processing temperature equal to or above 200° c. ... Purdue Research Foundation

12/21/17 / #20170360709

Carrier-free nanoparticles

A carrier free nanoparticle formulation with good circulation stability is made for anticancer drug delivery. Nanocrystals crystalized in the medium containing pluronic f-127 then coated with albumin (cim-f-alb) had the smallest size and the most native albumin, and showed most favorable cell interaction profiles and better stability than commercial albumin based abraxane formulation, while maintaining comparable cytotoxicity to those of abraxane and solvent-dissolved paclitaxel (ptx).. ... Purdue Research Foundation

12/14/17 / #20170354758

Glycosaminoglycan-based materials as an engineered biocompatible cellular matrix

Disclosed herein is a cross-linked polymeric system comprising thiolated hyaluronic acid (ha), thiolated chondroitin sulfate (cs), and functionalized polyethylene glycol (peg), wherein said functionalized peg cross-links thiolated ha and thiolated cs. Methods of fabrication and utilization of the same are also claimed. ... Purdue Research Foundation

12/14/17 / #20170354118

Nesting material baling and dispensing system for mouse environmental enrichment

A standardized nesting material for use in laboratory environments for rodents includes a latrining substrate, and at least one bale unit formed to include a fibrous scaffolding material, and an insulating material. The bale units are of standardized size and can be packaged and sterilized to provide improved wellbeing of the animals; reduced feed and labor costs; and improved scientific quality of the studies conducted on the animals.. ... Purdue Research Foundation

12/07/17 / #20170349903

Sirna compositions that specifically downregulate expression of a variant of the pnpla3 gene and methods of use thereof for treating a chronic liver disease or alcoholic liver disease (ald)

The invention provides sirna compositions that specifically downregulates expression of a variant of the pnpla3 gene and methods of use thereof for treating a chronic liver disease or alcoholic liver disease (ald).. . ... Purdue Research Foundation

12/07/17 / #20170349547

Conducting reactions in leidenfrost-levitated droplets

The invention generally relates to conducting reactions in leidenfrost-levitated droplets.. . ... Purdue Research Foundation

11/30/17 / #20170343987

Microcontroller energy management system

A microcontroller system which employs an intermediate approach in hybrid fram-sram that involves memory mapping of program sections to retain the reliability benefits provided by fram while performing almost as efficiently as an sram-based system. They system utilizes an energy-aware memory mapping method which maps different program sections to the hybrid fram-sram mcu such that energy consumption is minimized without sacrificing reliability. ... Purdue Research Foundation

11/30/17 / #20170343526

Methods of analyzing crude oil

The invention generally relates to methods of analyzing crude oil. In certain embodiments, methods of the invention involve obtaining a crude oil sample, and subjecting the crude oil sample to mass spectrometry analysis. ... Purdue Research Foundation

11/30/17 / #20170343485

Retrieval of p-band soil reflectivity from signals of opportunity

A system and method for determining moisture content of soil, comprising providing bistatic radar configuration to measure soil reflectivity in uhf and s-band, cross-correlating between sky-viewed and earth-viewed signals and reflected signals in order to isolate the reflected signals, and correlating the isolated reflectesd signal to moisture content of the soil.. . ... Purdue Research Foundation

11/30/17 / #20170343481

Methods and systems for crack detection

Systems and methods suitable for capable of autonomous crack detection in surfaces by analyzing video of the surface. The systems and methods include the capability to produce a video of the surfaces, the capability to analyze individual frames of the video to obtain surface texture feature data for areas of the surfaces depicted in each of the individual frames, the capability to analyze the surface texture feature data to detect surface texture features in the areas of the surfaces depicted in each of the individual frames, the capability of tracking the motion of the detected surface texture features in the individual frames to produce tracking data, and the capability of using the tracking data to filter non-crack surface texture features from the detected surface texture features in the individual frames.. ... Purdue Research Foundation

11/30/17 / #20170342461

Tyrosine kinase biosensors and methods of use

Disclosed are compositions and methods for measuring tyrosine kinase activity.. . ... Purdue Research Foundation

11/23/17 / #20170336431

System and method for measuring exhaust flow velocity of supersonic nozzles

A system for measuring supersonic nozzle exhaust flow, comprising a seeding module, an optics module configured to direct an optical signal from the supersonic nozzle, and a streak camera. The streak camera is optically connected to the optical signal, the streak camera configured to image the path of the seed particles traveling in the nozzle exhaust flow. ... Purdue Research Foundation

11/16/17 / #20170331109

Methods of making electrodes, electrodes made therefrom, and electrochemical energy storage cells utilizing the electrodes

Method of making interconnected layered porous carbon sheets with porosity within the carbon sheets and in-between the carbon sheets for use as an electrode. Method of making a metal-nanoparticle carbon composite, wherein metal particles are surrounded by shells made of amorphous carbon. ... Purdue Research Foundation

11/16/17 / #20170330070

Spin orbit torque based electronic neuron

An electronic neuron device that includes a thresholding unit which utilizes current-induced spin-orbit torque (sot). A two-step switching scheme is implemented with the device. ... Purdue Research Foundation

11/16/17 / #20170326689

Methods of forming a substrate having an open pore therein and products formed thereby

Methods and products formed thereby that include depositing a light-absorbing particle on a substrate and irradiating the particle with a pulsed laser beam to cause an increase in local temperature of a portion of the substrate contacted by and adjacent to the particle, enabling the particle to penetrate and migrate through the substrate to form a pore. The methods may include additional steps of applying a magnetic field gradient to the particle as the particle is irradiated with the laser beam in order to promote the movement of the particle within the substrate or to direct the movement of the particle within the substrate, and/or the step of filling the pore with a material that provides a functional capability independent of the properties of the substrate.. ... Purdue Research Foundation

11/09/17 / #20170320992

Poly(alkylene carbonate)-based amphiphilic block copolymers and methods of use thereof

This invention provides poly(alkylene carbonate)-based amphiphilic block copolymers, compositions comprising the same, e.g., micelles, and methods of use thereof. This invention further provides methods for preparing the poly(alkylene carbonate)-based amphiphilic block copolymers of the invention.. ... Purdue Research Foundation

11/09/17 / #20170320164

Laser-assisted micromachining systems and methods

Laser-assisted micromachining methods and systems capable of providing flexible beam positioning and low incident angles. Such laser-assisted micromachining systems preferably include a laser beam source, a cutting tool, means for engaging a workpiece with the cutting tool, optical elements arranged to define a path of a laser beam emitted by the laser beam source wherein the optical elements include at least a first mirror mounted in fixed relation to the laser beam source, and means for adjustably mounting a second mirror to project the laser beam onto the workpiece in proximity to the cutting tool and at an incidence angle relative to a surface of the workpiece.. ... Purdue Research Foundation

11/09/17 / #20170319657

Method of treating a bladder cancer using a chimeric egf-targeted bacterial toxin

Provided is a method of treating a bladder cancer in an animal or human comprising: administering to an animal or human patient a therapeutic composition comprising a first fusion protein capable of specifically binding to an epidermal growth factor receptor (egfr) on the surface of a cancer cell and comprising an epidermal growth factor (egf) polypeptide conjugated to a bacterial toxin polypeptide and a second fusion protein comprising an anthrax lethal factor n-terminus (lfn) conjugated to a diptheria toxin a (dta) catalytic domain.. . ... Purdue Research Foundation

10/26/17 / #20170309462

Mass spectrometry analysis of microorganisms in samples

The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.. . ... Purdue Research Foundation

10/26/17 / #20170307533

Metal-antibody tagging and plasma-based detection

An apparatus and method for characterizing a target, e.g., microbial samples or biological toxins, includes labeling the target with a biomolecular recognition construct and measuring an atomic-spectra signal of the biomolecular recognition construct. The method can include heating the labeled target before measuring the atomic-spectra signal. ... Purdue Research Foundation

10/12/17 / #20170290900

Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics

Cytotoxic lymphocytes expressing chimeric antigen receptors (car) that target and bind small conjugate molecules (scm) are disclosed, as well as methods of using the cells and the scms in the treatment of cancer.. . ... Purdue Research Foundation

10/05/17 / #20170287690

Ion focusing

The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. ... Purdue Research Foundation

10/05/17 / #20170286815

Generating an object map from a plurality of binary images

In an example, a method is described that includes dividing an input image into a plurality of strips, where each strip is smaller than a whole of the input image. A plurality of binary images is then generated, where each of the binary images corresponds to one of the strips. ... Purdue Research Foundation

10/05/17 / #20170285262

Passive optical diode on semiconductor substrate

A method of fabricating an optical device includes forming on a semiconductor substrate a first optical cavity, a second optical cavity, a first light guide and a second light guide. The first light guide has an input, and is optically coupled to the first optical cavity by a first coupling strength. ... Purdue Research Foundation

10/05/17 / #20170284935

System and method for sensing and trapping nanoparticles with plasmonic nanopores

An apparatus for trapping and sensing nanoparticles using plasmonic nanopores, comprising a conductive transparent layer, a conductive film layer mounted to a substrate, the film layer comprising a plurality of nanopores for trapping nanoparticles contained in a fluid situated between the conductive transparent layer and the conductive film layer, and an electric field source connected between the transparent layer and the film layer.. . ... Purdue Research Foundation

10/05/17 / #20170283852

Novel ubiquitination system and the uses thereof

An unprecedented mechanism of ubiquitination that is independent of e1 and e2 enzymes, instead relying on activation of ubiquitin by adp-ribosylation, and which is mediated by members of the side effector family encoded by the bacterial pathogen legionella pneumophila is disclosed. The herein disclosed method demonstrates a method in which ubiquitination can be carried out by a single enzyme. ... Purdue Research Foundation

09/28/17 / #20170280106

Pubic safety camera identification and monitoring system and method

A system for determining a travel path, including a network of at least one camera, a communication hub coupled to the network of at least one camera, at least one electronic communication device, and a data processing system coupled to the communication hub, the data processing system comprising one or more processors configured to calculate a travel path based on user-specified criteria including maximum camera coverage, where the system is adapted to dynamically identify a plurality of cameras.. . ... Purdue Research Foundation

09/28/17 / #20170280105

Pubic safety camera monitoring system and method

A system for determining a travel path, including a network of at least one camera, a communication hub coupled to the network of at least one camera, at least one electronic communication device, and a data processing system coupled to the communication hub, the data processing system comprising one or more processors configured to calculate a travel path based on user-specified criteria including maximum camera coverage.. . ... Purdue Research Foundation

09/28/17 / #20170279384

Motor control system and method

A motor control interface system, comprising an interface communication module configured to connect to a wired control port of a rotating electronically controlled motor, such as in an hvac system, wherein the interface communication module converts a rotating motor speed signal to a wireless signal for receipt by an external monitoring device. The speed output signal comprises a digital square wave signal, and the communication module implements a reciprocal frequency counter method to determine the speed of the motor. ... Purdue Research Foundation

09/28/17 / #20170275713

Compositions and methods for treating leather

The present disclosure provides a composition for treating leather and similar materials. The composition comprises from about 40% (w/w) to about 60% (w/w) of an oil obtained from natural sources; from about 1% (w/w) to about 15% (w/w) of a wax obtained from natural sources; and from about 20% (w/w) to about 50% (w/w) of water. ... Purdue Research Foundation

09/28/17 / #20170275345

Collagen-binding synthetic peptidoglycans, preparation, and methods of use

This invention relates to collagen-binding synthetic peptidoglycans and engineered collagen matrices comprising a collagen matrix and a collagen-binding synthetic peptidoglycan where the collagen-binding synthetic peptidoglycan can be aberrant or can have amino acid homology with a portion of the amino acid sequence of a protein or a proteoglycan that regulates collagen fibrillogenesis. The invention also relates to kits, compounds, compositions, and engineered graft constructs comprising such collagen-binding synthetic peptidoglycans or engineered collagen matrices and methods for their preparation and use.. ... Purdue Research Foundation

09/28/17 / #20170274120

Collagen-based therapeutic delivery systems

A collagen-based therapeutic delivery device includes an insoluble synthetic collagen-fibril matrix comprising a polymerization product of soluble oligomeric collagen or a polymerization product of a mixture of soluble oligomeric collagen with one or more type of non-oligomeric soluble collagen molecules, such as, for example, soluble telocollagen and/or soluble atelocollagen, and an active agent dispersed throughout the collagen-fibril matrix or within a portion of the collagen-fibril matrix. A pre-matrix composition includes an aqueous solution including soluble collagen-fibril building blocks and an active agent in the aqueous solution. ... Purdue Research Foundation

09/28/17 / #20170273731

Novel technique for therapeutic contact lens systems

The invention relates to electronic contact lens systems, methods for fabrication thereof, and uses thereof for treatment of ophthalmic diseases and conditions, for example, meibomian gland dysfunction.. . ... Purdue Research Foundation

09/28/17 / #20170273605

Enclosed desorption electrospray ionization probes and method of use thereof

The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of desi-active spray, in which a distal portion of the source is enclosed within a transfer member such that the desi-active spray is produced within the transfer member.. ... Purdue Research Foundation

09/28/17 / #20170273256

Botanical air filtration system and method

A system and process for filtering air by removing pollutants from the air with living plants. The system includes an enclosure, a wall within the enclosure on which living plants are supported and grow in one or more horizontal plant beds defining vertical tiers along the wall, an irrigation system for watering the plants, and a lighting system for simulating sunlight. ... Purdue Research Foundation

09/21/17 / #20170269300

Single photon source

The invention related to single photon emission systems based on nano-diamonds. Single-photon sources have a broad range of applications in quantum communication, quantum computing and quantum metrology.. ... Purdue Research Foundation

09/21/17 / #20170267667

Alkenyldiarylmethanes as non-nucleoside reverse transcriptase inhibitors for anti-hiv-1 chemotherapy

The invention disclosed herein pertains to compounds of alkenyldiarylmethanes (adams) as non-nucleoside reverse transcriptase inhibitors (nnrtis) for the treatment of patients with acquired-immune deficiency syndrome (aids). Also described are methods for treating aids patients using the described alkenyldiarylmethane compounds.. ... Purdue Research Foundation

09/21/17 / #20170266719

Hot-chamber die casting systems and methods

Hot-chamber die casting systems for casting aluminum, copper, titanium, and their alloys, as well as other high temperature and/or reactive metals. The hot-chamber die casting system comprises an injection system that includes a cylinder, a plunger reciprocable within the cylinder, and a gooseneck that defines a passage fluidically connected to a cylinder chamber within the cylinder, wherein surfaces of the cylinder, plunger, and gooseneck that contact a molten metal during injection casting are defined by a refractory material that does not react with the molten metal, or have been treated to reduce the rate of dissolution of their surface material into the molten metal during injection casting.. ... Purdue Research Foundation

09/21/17 / #20170266303

Methods of treating cancer by targeting tumor-associated macrophages

Methods for treating cancers using one or more compounds comprising a folate receptor binding ligand attached to a drug via a linker are described. Methods for treating cancers using one or more compounds comprising a folate receptor binding ligand attached to a drug via a linker to target tumor associated macrophages are described.. ... Purdue Research Foundation

09/14/17 / #20170262726

Tex line detection

A system and method for text line detection are described examples include detection of symbols in an image received from an image-capturing device. In examples, for each of at least some of the symbols, neighboring symbols within a local region a given distance from the symbol are analyzed in order to determine a direction for a line in the local regions in examples, based on the determined directions for the lines, text lines in the image are identified.. ... Purdue Research Foundation

09/14/17 / #20170258923

Psma binding ligand-linker conjugates and methods for using

Described herein are prostate specific membrane antigen (psma) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. ... Purdue Research Foundation

09/07/17 / #20170256406

Processes for shaping nanomaterials

Processes for shaping one- and two-dimensional nanomaterials, and thereby inducing local strains therein preferably to control one or more of their material properties. The processes include providing a substrate comprising a three-dimensional surface feature thereon, locating a nanomaterial on the substrate and over the surface feature, and directing a laser beam toward the nanomaterial such that the nanomaterial experiences laser shock pressure sufficient to deform the nanomaterial to conform at least partially to the shape of the surface feature and adhere to the surface feature either directly or via an intermediate layer therebetween.. ... Purdue Research Foundation

09/07/17 / #20170253962

Plasma-enhanced chemical vapor deposition methods for graphene deposition

A graphene deposition process. The process includes the steps of placing a substrate into a deposition chamber and heating the chamber, generating radio frequency plasma at a location proximate to the substrate while flowing a precursor gas containing carbon through the plasma and over the substrate.. ... Purdue Research Foundation

09/07/17 / #20170252459

Multivalent fibronectin-integrin binding compositions and methods of use thereof

The invention provides multivalent fibronectin-integrin binding compositions and methods of use thereof. In certain embodiments, the invention provides peptide compositions that include at least two fibronectin binding peptides coupled together as a cancer therapeutic or a diagnostic tool.. ... Purdue Research Foundation

08/31/17 / #20170249550

Electronic synapse having spin-orbit torque induced spiketiming dependent plasticity

An electronic synapse is disclosed, comprising a heavy metal layer having a high spin orbit coupling, a domain wall magnet layer having a bottom surface adjacent to a top surface of the heavy metal layer, the domain wall magnet layer having a perpendicular magnetic anisotropy, the domain wall magnet layer having a domain wall, the domain wall running parallel to a longitudinal axis of the domain wall magnet layer, a pinned layer having perpendicular magnetic anisotropy, and an oxide tunnel barrier connected between the domain wall magnet layer and the pinned layer, wherein the pinned layer, the oxide tunnel barrier, and the free layer form a magnetic tunnel junction.. . ... Purdue Research Foundation

08/31/17 / #20170248707

Compositions and methods for detecting radiation

Tensioned metastable fluid detectors are disclosed that minimize false positive detection events. The methods involve the use of new fluids that provide improved neutron-alpha fission detection at reduced tension states. ... Purdue Research Foundation

08/31/17 / #20170248607

Analyzing a metabolite level in a sample

The invention generally relates to methods for analyzing a metabolite level in a sample. In certain embodiments, methods of the invention may involve obtaining a sample, analyzing the sample using a mass spectrometry technique to determine a level of at least one metabolite in the sample, and correlating the metabolite level with an originating source of the sample, thereby analyzing the sample.. ... Purdue Research Foundation

08/31/17 / #20170247555

Aqueous ink composition

Provided in one example herein is an aqueous ink composition, comprising: pigment particles comprising at least one metal oxide; an aqueous medium; and a cationic double-chain surfactant comprising a quaternary ammonium salt. Methods of making and using the ink composition are also provided.. ... Purdue Research Foundation

08/24/17 / #20170243672

Composite transparent conducting films and methods for production thereof

A composite transparent conducting film (tcf) on a substrate that includes a first region extending to a first depth of the tcf and having a higher density (lower porosity) than a second region of the tcf located at a different depth of the tcf. A method of forming the composite tcf includes applying a transparent conducting layer onto a substrate or onto a second layer previously formed on the substrate, and rapidly heating the transparent conducting layer resulting in a first region extending to a first depth of the transparent conducting layer that is at least partially melted and of a higher density (lower porosity) than a second region located at a different depth of the transparent conducting layer that is not melted, thereby forming a composite tcf that has a change of porosity in a thickness direction of the composite tcf.. ... Purdue Research Foundation

08/24/17 / #20170240484

Solid-rocket propellants

Solid-fuel rocket propellants comprising an oxidizer, an oxophilic metal-halophilic metal formulation, and a binder are described herein. Further described are processes for preparing such propellants and methods of reducing hydrogen chloride production via the combustion of such propellants. ... Purdue Research Foundation

08/24/17 / #20170238712

Chair, stool assembly, and system

A chair including structural members having hinge joints at ends thereof pivotally coupling each of the members to one or more adjoining members. The chair is configured to be arranged in a collapsed configuration wherein all of the members are in the same plane and define a substantially planar shape, and configured to be arranged in an expanded configuration to define a seat, armrests, support legs, and leg braces of the chair. ... Purdue Research Foundation

08/17/17 / #20170235162

Time-varying metasurface structure

A time-varying optical metasurface, comprising a plurality of modulated nano-antennas configured to vary dynamically over time. The metasurface may be implemented as part of an optical isolator, wherein the time-varying metasurface provides uni-directional light flow. ... Purdue Research Foundation

08/17/17 / #20170235021

Methods of forming particulate films and films and devices made therefrom

A method of depositing a film comprising a monolayer of particles. The method includes providing a dispersion comprising particles and at least two liquids and depositing drops of the dispersion onto a substrate and evaporating the at least two liquids resulting in a film of a monolayer of the particles. ... Purdue Research Foundation

08/17/17 / #20170232611

Educational systems comprising programmable controllers and methods of teaching therewith

Systems and methods for hands-on training of students. Such a system includes one or more programmable controllers configured to interact with one or more external devices. ... Purdue Research Foundation

08/17/17 / #20170232119

Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors

The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods and compositions for incorporating the compounds as used for the targeted imaging of non-small cell lung cancer (nsclc) in human subjects. ... Purdue Research Foundation

08/17/17 / #20170231853

Device and methods for movement assistance

Assistive movement devices and methods therefor are provided that are capable of redirecting loads from an individual's foot to hip when an individual is recovering from an injury at or below the knee. The devices include a frame assembly comprising an upper member, a lower member, and a joint therebetween. ... Purdue Research Foundation

08/10/17 / #20170223943

Automatic monitoring of insect populations

Illustrative embodiments of integrated pest management (ipm) systems and electronic insect monitoring devices (eimds) are disclosed. In some embodiments, the eimds may each comprise a lure for attracting at least one target insect species, one or more sensors configured to generate one or more output signals in response to an individual insect approaching the lure, and an electronic controller configured to count a number of individual insects approaching the lure. ... Purdue Research Foundation

08/03/17 / #20170221695

Systems and methods for ejection of ions from an ion trap

The invention generally relates to systems and methods for ejection of ions from an ion trap. In certain embodiments, systems and methods of the invention sum two different frequency signals into a single summed signal that is applied to an ion trap. ... Purdue Research Foundation

08/03/17 / #20170219485

Organism identification

A system for the identification of micro-organisms includes an irradiation unit adapted to sequentially provide coherent electromagnetic radiation of one or more wavelengths along a common optical path. A holder is adapted to retain a substrate having a surface adapted for growth of a micro-organism colony. ... Purdue Research Foundation

08/03/17 / #20170217996

Large-scale diastereoselective syntheses of cycloheptadienylsulfones and stereotetrads

The invention relates to processes for large-scale diastereoselective syntheses of cycloheptadienylsulfone and stereotetrads, key intermediates for the preparation of aplyronine a.. . ... Purdue Research Foundation

08/03/17 / #20170216465

Design and development of neurokinin-1 receptor-binding agent delivery conjugates

Neurokinin-1 (nk-1) receptor-binding agent delivery conjugates, compositions comprising nk-1 receptor-binding agent delivery conjugates, and methods for making and administering nk-1 receptor-binding agent delivery conjugates are provided. A conjugate may include an nk-1 receptor-binding moiety, a linker group containing at least one linker selected from the group of a releasable linker and a spacer linker, and an active agent linked to the linker group. ... Purdue Research Foundation

07/27/17 / #20170212053

Characterization of trace crystallinity by second harmonic generation microscopy

A method for quantifying crystallinity within a sample using second harmonic generation microscopy is described herein. In one aspect, a method for reducing the timeframe for accelerated stability testing of amorphous solid dispersions of active pharmaceutical ingredients though identifying regions of interest to quantify crystallinity and composition is presented herein.. ... Purdue Research Foundation

07/27/17 / #20170211033

Production of hydrogen using an anaerobic biological process

Various embodiments of the present invention pertain to methods for biological production of hydrogen. More specifically, embodiments of the present invention pertain to a modular energy system and related methods for producing hydrogen using organic waste as a feed stock.. ... Purdue Research Foundation

07/20/17 / #20170207986

Tracing message transmissions between communicating network devices

A packet of data and a packet-identification value are transmitted to a network device having an identifier. The stored packet-identification value and the identifier are recorded. ... Purdue Research Foundation

07/13/17 / #20170201614

Mobile device enabled robotic system

An unmanned aerial vehicle (uav) equipped with sensor modules and mobile devices (including smartphone, tablet) running intelligent software for autonomous navigation, onboard computer vision, communication, and robotic social networks, is disclosed herein.. . ... Purdue Research Foundation

07/13/17 / #20170201335

Methods and devices for real-time monitoring of tunable filters

Methods and devices suitable for monitoring the frequency of microwave tunable filters in real time. The frequency readout relies on the natural response of such a filter when excited by a pulse. ... Purdue Research Foundation

07/13/17 / #20170199977

Method for patient genotyping

The present invention is a system and method for utilizing human genetic and genomic information to guide prescription dispensing and improved drug safety in a pharmacy setting. The system and method of the present invention utilizes a dedicated information management system and software to utilize patient-specific genetic information to screen for increased risk of adverse drug reactions and therapeutic responses at the time of drug dispensing.. ... Purdue Research Foundation

07/13/17 / #20170196481

Systems and methods for determining a concentrationof glucose in exhaled breadth

The invention generally relates to systems and methods for determining a concentration of glucose in exhaled breadth. In certain aspects, the invention provides a system including a sample collection module configured to collect a condensate sample produced from a mixture of exhaled breadth from a subject and ambient air. ... Purdue Research Foundation

07/06/17 / #20170193144

Asynchronous simulation steering system

A system which receives a plurality of high-fidelity simulation data models that together form an asynchronous simulation pipeline, determines low-fidelity approximations of the received simulation data models using local simulation proxies, and displays the approximations on a display for a user to enable the user to interactively configure a simulation run.. . ... Purdue Research Foundation

07/06/17 / #20170190798

Proteoliposome and production method thereof

The invention discloses a method to prepare proteoliposomes using glycerol or polyethylene glycols (peg) in the rehydration step. The method eliminates the use of expensive surfactants and subsequent time-consuming removal of those surfactants during the preparation of proteoliposomes. ... Purdue Research Foundation

07/06/17 / #20170189556

Repurposing non-antimicrobial drugs and clinical molecules to treat bacterial infections

Disclosed herewith is drug repurposing efforts that lead to the discovery of prior non-antibiotic drugs can be used in clinical applicable ranges to treat patients of bacterial infection. These repurposed drug can be used either alone or in combination with traditional antibiotic drugs to treat bacterial strains that may develop or already have developed drug resistance.. ... Purdue Research Foundation

06/29/17 / #20170184569

Screening assay for choice of prebiotic to prevent/treat gastrointestinal and systemic diseases

An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided.. . ... Purdue Research Foundation

06/29/17 / #20170183710

Tyrosine kinase biosensors and methods of use

The present disclosure illustrates new synthetic alk-specific biosensors used to measure the activity or alk, and methods of using the synthetic alk-specific biosensors in assays, including high throughput assays.. . ... Purdue Research Foundation








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