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Quark Pharmaceuticals Inc patents (2016 archive)


Recent patent applications related to Quark Pharmaceuticals Inc. Quark Pharmaceuticals Inc is listed as an Agent/Assignee. Note: Quark Pharmaceuticals Inc may have other listings under different names/spellings. We're not affiliated with Quark Pharmaceuticals Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "Q" | Quark Pharmaceuticals Inc-related inventors


Methods and compositions for neuroprotection

Disclosed herein are methods and kits useful for providing neuroprotection to neurons in the inner ear and to methods of treating inner ear diseases and disorders, including tinnitus and ménière's disease.. . ... Quark Pharmaceuticals Inc

Double stranded oligonucleotide compounds comprising positional modifications

Disclosed herein are double stranded rna molecules which have been modified to exhibit one of the following, increased activity, enhanced nuclease stability, reduced off target activity and or reduced immunogenicity, to pharmaceutical compositions comprising such compounds and to methods of use. Further disclosed is a method for the synthesis of threose nucleic acid phosphoramidites and methods of use thereof.. ... Quark Pharmaceuticals Inc

Oligonucleotide modulators of the toll-like receptor pathway

Disclosed herein are double stranded nucleic acid molecules and pharmaceutical compositions comprising same useful in the treatment of, inter alia, acute and chronic inflammation, neuropathic pain, primary graft dysfunction (pgd) after lung transplantation in a subject in need thereof. The compounds are preferably chemically synthesized and modified dsrna compounds, which down regulate or inhibit expression of toll like receptor 4.. ... Quark Pharmaceuticals Inc

Double stranded rna compounds to rhoa and use thereof

The present invention relates to compounds, pharmaceutical compositions comprising same, methods of use thereof and kits for the down-regulation of rhoa gene. The compounds, compositions, methods and kits are useful in the treatment of subjects suffering from diseases or conditions and or symptoms associated with diseases or conditions in which rhoa expression has adverse consequences and for conferring neuroprotection.. ... Quark Pharmaceuticals Inc

Double-stranded rna compounds to casp2 and uses thereof

The present disclosure relates to methods of treating a patient suffering from or at risk of developing an ocular disease, disorder or injury, and includes treatment regimens using a double-stranded rna compound that down-regulates casp2 expression, or a pharmaceutically acceptable salt thereof.. . ... Quark Pharmaceuticals Inc








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