R p Scherer Technologies Llc patents

Antibody conjugates and methods of making and using the same

Antibodies that include a sulfatase motif-containing tag in a constant region of an immunoglobulin (Ig) light chain polypeptide are disclosed. The sulfatase motif can be converted by a formylglycine-generating enzyme (FGE) to produce a formylglycine (fGly)-modified Ig light chain polypeptide. An fGly-modified Ig light chain polypeptide of the antibody can... R p Scherer Technologies Llc

Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate

The present disclosure provides conjugate structures and hydrazinyl-substituted heteroaryl compounds used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates and compounds, as well as methods of using the same.... R p Scherer Technologies Llc

Multiple-fluid injection pump

The invention provides a pump for dispensing a plurality of fluids at predetermined volumes to a common location and a method of using the pump to deliver such plurality of fluids. The pump comprises one or more first syringe units, each first syringe unit comprising a first plunger and a... R p Scherer Technologies Llc

Capsule dispensing container

A package for delivering a single-dose product includes a softgel capsule which is comprised of at least one gelling agent selected from protein-based gelling agents and polysaccharide-based gelling agents. The capsule shell includes one or more areas of reduced thickness that are preferentially ruptured by exertion of a compressive force... R p Scherer Technologies Llc

Topical anhydrous fill formulation for ultraviolet filters

An anhydrous base composition including a branched hydrocarbon base oil having 9-16 carbon atoms and a viscosity adjusting agent suitable for use in the formulation of a cosmetic composition and which is compatible with a variety of capsule technologies. Also described is a storage stable anhydrous fill formulation compatible with... R p Scherer Technologies Llc

Methods for manufacturing encapsulated granular material, methods for drying coating materials, and fluidized bed dryers

Disclosed is a method for shortening the drying time for drying an encapsulated material including a coating material containing water without causing deformation of the coating when drying. The method employs a fluidized bed dryer for drying coating materials that contain water and that form a coating when the water... R p Scherer Technologies Llc

Process for recovery of waste gel-mass from softgel manufacturing process

A process and system for recovering gel-mass from a gel-mass-containing waste material. The process comprises retrieving the gel-mass-containing waste material from an encapsulation process; melting the retrieved waste material to provide an oil phase and a non-oil phase; retrieving the non-oil phase to produce a recovered gel-mass; and recycling the... R p Scherer Technologies Llc

Extended release film-coated capsules

Pharmaceutical formulations, preferably in the form of softgel capsules or hard-shell capsules, exhibit extended release through the use of a coating comprising a water-insoluble polymer and a pH-independent pore former. Extended release from softgel capsules and hard-shell capsules can be achieved without the use of lipid-based semi-solid or solid materials.... R p Scherer Technologies Llc