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Research Corporation Technologies Inc patents


Recent patent applications related to Research Corporation Technologies Inc. Research Corporation Technologies Inc is listed as an Agent/Assignee. Note: Research Corporation Technologies Inc may have other listings under different names/spellings. We're not affiliated with Research Corporation Technologies Inc, we're just tracking patents.

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Artificial antibody polypeptides

The present invention provides a fibronectin type III (Fn3) molecule, wherein the Fn3 contains a stabilizing mutation. The present invention also provides Fn3 polypeptide monobodies, nucleic acid molecules encoding monobodies, and variegated nucleic acid libraries encoding such monobodies. Also provided are methods of preparing a Fn3 polypeptide monobody, and kits... Research Corporation Technologies Inc

Small antibody-like polypeptides that bind to epha2 receptor

The present disclosure is directed to a modified isolated immunoglobulin CH2 domain that specifically binds to an extracellular region of an EphA2 receptor, wherein the amino acid sequence of the modified immunoglobulin CH2 domain includes at least one amino acid substitution, addition or deletion in comparison to a wild type... Research Corporation Technologies Inc

Ribotoxin molecules derived from sarcin and other related fungal ribotoxins

The present application relates to modified T cell epitopes derived from fungal ribotoxins, including α-sarcin, clavin, gigantin, mitogillin, and restrictocin, as well as modified ribotoxin molecules comprising one or more of the modified epitopes. The modified ribotoxin molecules inhibit protein synthesis, like the wild type ribotoxins, but exhibit reduced immunogenicity... Research Corporation Technologies Inc

Pichia pastoris strains for producing predominantly homogeneous glycan structure

Disclosed herein are novel Pichia pastoris strains for expression of exogenous proteins with substantially homogeneous N-glycans. The strains are genetically engineered to include a mutant OCH1 allele which is transcribed into an mRNA coding for a mutant OCH1 gene product (i.e., α-1,6-mannosyltransferase, or “OCH1 protein”). The mutant OCH1protein contains a... Research Corporation Technologies Inc

Pichia pastoris surface display system

This disclosure relates to novel Pichia pastoris display systems, e.g., display systems featuring the Pichia pastoris strains (such as SuperMan5) with substantially homogeneous N-glycans displayed on cell surface proteins.... Research Corporation Technologies Inc








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