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Sangamo Biosciences Inc
Sangamo Biosciences Inc And Whitehead Institute For Biomedical Research

Sangamo Biosciences Inc patents


Recent patent applications related to Sangamo Biosciences Inc. Sangamo Biosciences Inc is listed as an Agent/Assignee. Note: Sangamo Biosciences Inc may have other listings under different names/spellings. We're not affiliated with Sangamo Biosciences Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "S" | Sangamo Biosciences Inc-related inventors


Compositions for linking dna-binding domains and cleavage domains

Disclosed herein are compositions for linking DNA binding domains and cleavage domains (or cleavage half-domains) to form non-naturally occurring nucleases with alternative configurations. Also described are methods of making and using compositions comprising these linkers.... Sangamo Biosciences Inc

Targeted disruption of the t cell receptor

Disclosed herein are methods and compositions for inactivating TCR genes, using engineered nucleases comprising at least one DNA binding domain and a cleavage domain or cleavage half-domain in conditions able to preserve cell viability. Polynucleotides encoding nucleases, vectors comprising polynucleotides encoding nucleases and cells comprising polynucleotides encoding nucleases and/or cells... Sangamo Biosciences Inc

Methods and compositions for engineering immunity

Nucleases and methods of using these nucleases for expressing an antibody from a safe harbor locus in a secretory tissue, and clones and animals derived therefrom.... Sangamo Biosciences Inc

Targeted disruption of the mhc cell receptor

Disclosed herein are methods and compositions for inactivating MHC genes, using zinc finger nucleases (ZFNs) comprising a zinc finger protein and a cleavage domain or cleavage half-domain in conditions able to preserve cell viability. Polynucleotides encoding ZFNs, vectors comprising polynucleotides encoding ZFNs and cells comprising polynucleotides encoding ZFNs and/or cells... Sangamo Biosciences Inc

Methods and compositions for increasing rna activity in a cell

Disclosed herein are methods and compositions for increasing RNA activity in a cell.... Sangamo Biosciences Inc

Liver-specific constructs, factor viii expression cassettes and methods of use thereof

Described herein are constructs used for liver-specific expression of a transgene.... Sangamo Biosciences Inc

Htt repressors and uses thereof

Disclosed herein are Htt repressors and methods and compositions for use of these Htt repressors.... Sangamo Biosciences Inc

Targeted modification of malate dehydrogenase

Disclosed herein are methods and compositions for targeted modification of one or more endogenous plant malate dehydrogenase genes.... Sangamo Biosciences Inc

Fad2 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks

Methods and compositions for gene disruption, gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene in a soybean cell, to generate a break in the FAD2 gene and then optionally integrating into the break a nucleic acid... Sangamo Biosciences Inc

Methods and compositions for treating huntington's disease

Disclosed herein are compositions comprising non-naturally occurring zinc finger domains, fusion proteins comprising these zinc finger domains, polynucleotides encoding these proteins, cells expressing these proteins and pharmaceutical compositions comprising these proteins or polynucleotides as well as methods of modifying an Htt gene using these compositions for treating or preventing Huntington's... Sangamo Biosciences Inc

Delivery methods and compositions for nuclease-mediated genome engineering

The present disclosure is in the field of genome engineering, particularly targeted modification of the genome of a cell.... Sangamo Biosciences Inc

Novel dna-binding proteins and uses thereof

Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.... Sangamo Biosciences Inc








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



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