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Shionogi x26 Co Ltd
Shionogi x26 Co Ltd A Legal Entity Of Japan
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Shionogi & Co Ltd patents


Recent patent applications related to Shionogi & Co Ltd. Shionogi & Co Ltd is listed as an Agent/Assignee. Note: Shionogi & Co Ltd may have other listings under different names/spellings. We're not affiliated with Shionogi & Co Ltd, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "S" | Shionogi & Co Ltd-related inventors


9-membered fused ring derivative

R4 is substituted or unsubstituted alkylcarbonyl or the like.... Shionogi & Co Ltd

Crystal of 6,7-unsaturated-7-carbamoyl morphinan derivative and producing the same

an acid addition salt, and/or a solvate thereof are provided by the present invention. Said crystalline forms are extremely useful as materials for preparing medicines. Novel processes for preparing 6,7-unsaturated-7-carbamoyl morphinan derivatives are also provided by the present invention.... Shionogi & Co Ltd

Methods of producing compounds having hiv integrase inhibitory activity

A process for preparing a compound represented by formula (Y1) or (Y2) [wherein IV is an optionally substituted carbocyclyl lower alkyl, or the like] or a salt thereof, using a novel process for preparing a pyridone derivative represented by formula (X4) [wherein R1d is hydrogen, halogen, or the like; R2d... Shionogi & Co Ltd

Methods of producing compounds having hiv integrase inhibitory activity

A process for preparing a compound represented by formula (Y1) or (Y2) [wherein RX is an optionally substituted carbocyclyl lower alkyl, or the like] or a salt thereof, using a novel process for preparing a pyridone derivative represented by formula (X4) [wherein R1d is hydrogen, halogen, or the like; R2d... Shionogi & Co Ltd

Methods of producing compounds having hiv integrase inhibitory activity

A process for preparing a compound represented by formula (Y1) or (Y2) [wherein Rx is an optionally substituted carbocyclyl lower alkyl, or the like] or a salt thereof, using a novel process for preparing a pyridone derivative represented by formula (X4) [wherein R1d is hydrogen, halogen, or the like; R2d... Shionogi & Co Ltd

Methods of producing compounds having hiv integrase inhibitory activity

A process for preparing a compound represented by formula (Y1) or (Y2) [wherein Rx is an optionally substituted carbocyclyl lower alkyl, or the like] or a salt thereof, using a novel process for preparing a pyridone derivative represented by formula (X4) [wherein R1d is hydrogen, halogen, or the like; R2d... Shionogi & Co Ltd

Polycyclic carbamoylpyridone derivative having hiv integrase inhibitory activity

R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.... Shionogi & Co Ltd

Aminotriazine derivative and pharmaceutical composition comprising the same

or its pharmaceutically acceptable salt.... Shionogi & Co Ltd

Substituted polycyclic carbamoyl pyridone derivative prodrug

The present invention provides a compound having antiviral effects, particularly having growth inhibitory activity on influenza viruses, a preferred example of the compound being a substituted 3-hydroxy-4-pyridone derivative prodrug having cap-dependent endonuclease inhibitory activity.... Shionogi & Co Ltd

Heterocyclic derivative having ampk-activating activity

R4, R5 and R6 are each independently hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, or the like.... Shionogi & Co Ltd

Heterocyclic ring and carbocyclic derivative

or its pharmaceutically acceptable salt.... Shionogi & Co Ltd

A salt of cephalosporin derivative, its crystalline solid and a manufacturing thereof

or their hydrate or a stable crystalline solid thereof. The salt or the crystalline solid is extremely useful as an active ingredient for the production of a pharmaceutical product.... Shionogi & Co Ltd

Preparation containing cephalosporin having a catechol moiety

The stable pharmaceutical composition can be prepared by comprising 1) a compound represented by formula (I), its pharmaceutically acceptable salt, or a solvate thereof, 2) one or more selected from the group consisting of alkali metal chlorides, alkaline earth metal chlorides, transition metal chlorides and magnesium chloride; and 3) sugar... Shionogi & Co Ltd

Azaindole derivative having ampk-activating activity

R4 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, or the like.... Shionogi & Co Ltd

Monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase

Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.... Shionogi & Co Ltd

Polycyclic carbamoylpyridone derivative having hiv integrase inhibitory activity

R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.... Shionogi & Co Ltd

Method for evaluation of drug efficacy of a medicine having a therapeutic or preventive effect against a disease related to el activity and a screening an inhibitor of el activity

The present invention is related to a method for evaluation of drug efficacy of a medicine having a therapeutic or preventive effect against a disease related to EL activity wherein phosphatidylinositol or lysophosphatidylinositol is used as an indicator. The present invention is also related to a method for screening an... Shionogi & Co Ltd

Polycyclic carbamoylpyridone derivative having hiv integrase inhibitory activity

R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.... Shionogi & Co Ltd

Humanized monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase

Provided is a humanized monoclonal antibody or an antibody fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.... Shionogi & Co Ltd

Long-acting hiv protease inhibitor

Z is substituted aromatic carbocyclyl, substituted non-aromatic carbocyclyl, substituted aromatic heterocyclyl or substituted non-aromatic heterocyclyl.... Shionogi & Co Ltd

Polycyclic carbamoylpyridone derivative having hiv integrase inhibitory activity

R4 and Z2 part taken together forms a ring, to form a polycyclic compound; including e.g., a tricyclic or tetracyclic compound.... Shionogi & Co Ltd

Heterocycle and carbocycle derivatives having trka inhibitory activity

wherein -L- is —C(═X)—, or the like, —Z— is —NR5—, or the like, —ZA— is —NR5A—, or the like, —W— is —C(R8R9)n-, —WA— is —C(R3R4)m-, B is substituted or unsubstituted aromatic carbocyclyl, or the like, Y is a bond, or the like, the ring C is a substituted or unsubstituted... Shionogi & Co Ltd

Methods of producing compounds having hiv integrase inhibitory activity

A process for preparing a compound represented by formula (Y1) or (Y2) [wherein Rx is an optionally substituted carbocyclyl lower alkyl, or the like] or a salt thereof, using a novel process for preparing a pyridone derivative represented by formula (X4) [wherein R1d is hydrogen, halogen, or the like; R2d... Shionogi & Co Ltd

Multi-layered tablet containing drug unstable to light

An oral disintegrating tablet which contains rosuvastatin or a salt thereof and is stable to light is provided. An oral disintegrating tablet stable to light, temperature and humidity can be provided by preparing a multi-layered tablet containing rosuvastatin or a pharmaceutically acceptable salt thereof as an active ingredient, a light... Shionogi & Co Ltd

Polycyclic carbamoylpyridone derivative having hiv integrase inhibitory activity

R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.... Shionogi & Co Ltd

Polycyclic carbamoylpyridone derivative having hiv integrase inhibitory activity

R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.... Shionogi & Co Ltd

Polycyclic pyridone derivative having integrase inhibitory activity

The present invention relates to a novel compound having an antiviral effect, more specifically, a pyridone derivative having HIV integrase inhibitory activity, and a medicament containing the same, in particular, an anti-HIV agent. The compound of the present invention has integrase inhibitory activity and/or cell proliferation inhibitory activity against viruses,... Shionogi & Co Ltd

Polycyclic carbamoylpyridone derivative having hiv integrase inhibitory activity

R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.... Shionogi & Co Ltd

Process for producing alkynylketone derivative

The present invention relates to a Sonogashira-Carbonylation reaction using two types of gas, as well as novel crystals which can control a heat of the said reaction and the process of producing the same. In addition, the present invention relates to a ligand (additive) to prevent the deactivation of a... Shionogi & Co Ltd

Polyene macrolide derivative

wherein each symbol is defined in description. The compound of the present invention has 16th position (X) is urea structure, cyclic structure, hydroxyalkyl or substituted monoalkylcarbamoyl. The compound of the present invention has antifungal activity.... Shionogi & Co Ltd

Trpv1 antagonists including dihydroxy substituent and uses thereof

and pharmaceutically acceptable derivatives thereof, where R1, R4, R8, R9, and m are as defined herein, compositions comprising an effective amount of a Compound of Formula (I) or a pharmaceutically acceptable derivative thereof, and methods for treating or preventing a condition such as pain, pain associated with osteoarthritis, osteoarthritis, UI,... Shionogi & Co Ltd

Pyrimidinone derivative having autotaxin-inhibitory activity

wherein R1, R2, R3, R4a, R4c, R5 are as defined in the description.... Shionogi & Co Ltd

Polycyclic carbamoylpyridone derivative having hiv integrase inhibitory activity

R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.... Shionogi & Co Ltd

Azabenzimidazole derivative having ampk-activating activity

Y is substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted heterocyclyl or the like.... Shionogi & Co Ltd

Tricyclic heterocycle derivatives having hiv replication inhibitory effect

the other symbols are as specified in the description.... Shionogi & Co Ltd

04/20/17 / #20170107521

Pharmaceutical composition for treating chronic kidney disease

This invention is related to a therapeutic agent for treating chronic kidney disease comprising a substance which inhibits the enzymatic activity of NNMT or suppresses NNMT gene expression, or a method for screening a therapeutic agent for treating chronic kidney disease which targets the NNMT enzyme or NNMT gene.... Shionogi & Co Ltd

03/16/17 / #20170073337

Dihydrothiazine and dihydrooxazine derivatives having bace1 inhibitory activity

or a pharmaceutically acceptable salt thereof.... Shionogi & Co Ltd

03/09/17 / #20170066754

Antiviral agent

(wherein, C ring is N-containing aromatic heterocycle) or the like).... Shionogi & Co Ltd

03/09/17 / #20170066759

Aromatic 5-membered heterocyclic derivative having trpv4-inhibiting activity

or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising thereof.... Shionogi & Co Ltd

03/09/17 / #20170066774

Crystal of 6,7-unsaturated-7-carbamoyl morphinan derivative and producing the same

an acid addition salt, and/or a solvate thereof are provided by the present invention. Said crystalline forms are extremely useful as materials for preparing medicines. Novel processes for preparing 6,7-unsaturated-7-carbamoyl morphinan derivatives are also provided by the present invention.... Shionogi & Co Ltd

02/09/17 / #20170035855

Medicinal agent for suppressing malignant tumor metastasis

A medicinal composition for suppressing or preventing the metastasis of a malignant tumor, the composition comprising, as an active ingredient, at least one kind of vasoprotective agent selected from the following (i) to (iv): (i) angiotensin II receptor antagonist, (ii) HMG-CoA reductase inhibitor, (iii) ghrelin or its derivative, and (iv)... Shionogi & Co Ltd

02/02/17 / #20170029438

Polycyclic carbamoylpyridone derivative having hiv integrase inhibitory activity

R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.... Shionogi & Co Ltd

01/12/17 / #20170008881

Dihydrooxazine or oxazepine derivatives having bace1 inhibitory activity

or a pharmaceutically acceptable salt thereof.... Shionogi & Co Ltd








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