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St Jude Children s Research Hospital Inc patents


Recent patent applications related to St Jude Children s Research Hospital Inc. St Jude Children s Research Hospital Inc is listed as an Agent/Assignee. Note: St Jude Children s Research Hospital Inc may have other listings under different names/spellings. We're not affiliated with St Jude Children s Research Hospital Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "S" | St Jude Children s Research Hospital Inc-related inventors


Methods for expanding immune cells

The present invention relates to a chimeric receptor capable of signaling both a primary and a co-stimulatory pathway, thus allowing activation of the co-stimulatory pathway without binding to the natural ligand. The cytoplasmic domain of the receptor contains a portion of the 4-1BB signaling domain. Embodiments of the invention relate... St Jude Children s Research Hospital Inc

Method for improving learning

The invention is directed to a method for improving learning and/or memory (e.g., auditory, visual, somatosensory or motor) in adults and children of an age which is beyond the early critical period for learning, said method comprising inhibiting (i) ecto-5′-nucleotidase (Nt5e, aka CD73) or (ii) A1 adenosine receptor (A1R, aka... St Jude Children s Research Hospital Inc

Chimeric receptors with 4-1bb stimulatory signaling domain

The present invention relates to a chimeric receptor capable of signaling both a primary and a co-stimulatory pathway, thus allowing activation of the co-stimulatory pathway without binding to the natural ligand. The cytoplasmic domain of the receptor contains a portion of the 4-1BB signaling domain. Embodiments of the invention relate... St Jude Children s Research Hospital Inc

System design and verifying 3d dosimetric imaging of charged particles in media

A method of verifying therapeutic proton beam delivery accuracy by ultrasound tomographic imaging to map three dimensional (3D) proton dose through the detection of ionizing radiation induced thermo-acoustic signal from the proton beam.... St Jude Children s Research Hospital Inc

Chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease

The invention provides a chimeric receptor comprising NKG2D, DAP10 and CD3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of NK cells. The invention also encompansses methods for use of NKG2D-DAP10-CD3 zeta polypeptides, vectors... St Jude Children s Research Hospital Inc

Treatments for gastrointestinal conditions

Compounds for the treatment of bacterial and parasitic infections which are hybrid compounds of compounds having antibacterial or antiparasitic activity and compounds that decrease the absorption of the hybrid compound from the gastrointestinal tract. The compounds are preferably for use against C. difficile infections and comprise a hybrid molecule of... St Jude Children s Research Hospital Inc

Modified natural killer cells and uses thereof

The present invention provides, in certain aspects, a natural killer (NK) cell that expresses all or a functional portion of interleukin-15 (IL-15), and methods for producing such cells. The invention further provides methods of using a natural killer (NK) cell that expresses all or a functional portion of interleukin-15 (IL-15)... St Jude Children s Research Hospital Inc

Methods of expanding ex vivo natural killer t (nkt) cells and therapeutic uses thereof

The present invention is directed to novel methods of producing ex vivo natural killer T (NKT) cells, and therapeutic uses thereof for treatment of certain conditions including cancer, autoimmunity, inflammatory disorders, allergic disorders, tissue transplant-related disorders, and infections.... St Jude Children s Research Hospital Inc








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