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Sutro Biopharma Inc patents


Recent patent applications related to Sutro Biopharma Inc. Sutro Biopharma Inc is listed as an Agent/Assignee. Note: Sutro Biopharma Inc may have other listings under different names/spellings. We're not affiliated with Sutro Biopharma Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "S" | Sutro Biopharma Inc-related inventors


Use of lambda-gam protein in ribosomal display technology

Methods and systems for increasing the stability of a nucleic acid template that encodes a protein of interest in a cell free translation system or a ribosomal display reaction system are described. In some embodiments, the nucleic acid template is an rna or mrna. ... Sutro Biopharma Inc

Anti-pd-1 antibodies, compositions comprising anti-pd-1 antibodies and methods of using anti-pd-1 antibodies

Provided herein are antibodies that selectively bind to pd-1 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.. ... Sutro Biopharma Inc

Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use

Provided herein are modified amino acids comprising a tetrazine groups according to formula i: polypeptides, antibodies, payloads and conjugates comprising these modified amino acid residues derived from the modified amino acids, and methods of producing the polypeptides, antibodies, payloads and conjugates comprising the modified amino acid residues. The polypeptides, antibodies, payloads and conjugates are useful in methods of treatment and prevention, methods of detection and methods of diagnosis.. ... Sutro Biopharma Inc

Codon optimization for titer and fidelity improvement

The invention provides methods for producing a protein in a cell free protein synthesis system such that the protein does not contain an asparagine (asn or n) residue at serine (ser or s) positions. Also provided are compositions and nucleic acid templates for use in the methods described herein.. ... Sutro Biopharma Inc

Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use

Provided herein are antibodies comprising multiple non-natural amino acid residues at site-specific positions, compositions comprising the antibodies, methods of their production and methods of their use. The antibodies are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.. ... Sutro Biopharma Inc

Formulations for drying bacterial cell extracts

This invention provides for an improved method of stabilizing freeze dried bacterial extracts with a carbohydrate lyoprotectant such that the extracts can be for use in cell free protein synthesis. Also provided herein are formulations for stable, freeze dried bacterial extracts that when stored at room temperature retain at least about 70% protein synthesis activity compared to undried frozen bacterial extracts.. ... Sutro Biopharma Inc

Modified fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use

Provided herein are modified fc proteins comprising non-natural amino acid residues at site-specific positions, conjugates of the modified fc proteins for therapy or diagnosis, compositions comprising the modified fc proteins and conjugates thereof, methods of their production and methods of their use. The modified fc proteins and conjugates are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.. ... Sutro Biopharma Inc

Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use

Provided herein are antibodies comprising non-natural amino acid residues at site-specific positions, compositions comprising the antibodies, methods of their production and methods of their use. The antibodies are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.. ... Sutro Biopharma Inc

Proteolytic inactivation of select proteins in bacterial extracts for improved expression

The present disclosure provides modified proteins that are capable of being cleaved by the protease ompt1. The proteins can be modified in an exposed surface motif to incorporate ompt1 cleavage sites. ... Sutro Biopharma Inc

Modified amino acids

Provided herein are modified amino acids comprising an azido group, polypeptides, antibodies and conjugates comprising the modified amino acids, and methods of producing the polypeptides, antibodies and conjugates comprising the modified amino acids. The polypeptides, antibodies and conjugates are useful in methods of treatment and prevention, methods of detection and methods of diagnosis.. ... Sutro Biopharma Inc

Modified amino acids

Provided herein are modified amino acids comprising an azido group, polypeptides, antibodies and conjugates comprising the modified amino acids, and methods of producing the polypeptides, antibodies and conjugates comprising the modified amino acids. The polypeptides, antibodies and conjugates are useful in methods of treatment and prevention, methods of detection and methods of diagnosis.. ... Sutro Biopharma Inc

Anti-cd74 antibodies, compositions comprising anti-cd74 antibodies and methods of using anti-cd74 antibodies

Provided herein are antibodies that selectively bind to cd74 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.. ... Sutro Biopharma Inc

High growth capacity auxotrophic escherichia coli and methods of use

This invention provides high growth capacity strains of auxotrophic escherichia coli and methods for generating thereof. The high growth capacity strains express a complementing auxotrophic plasmid that allows the strain to grow in the absence of the auxotrophic amino acid. ... Sutro Biopharma Inc








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