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Synaffix B v patents


Recent patent applications related to Synaffix B v. Synaffix B v is listed as an Agent/Assignee. Note: Synaffix B v may have other listings under different names/spellings. We're not affiliated with Synaffix B v, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "S" | Synaffix B v-related inventors


Sulfamide linker, conjugates thereof, and methods of preparation

Said compound may also be referred to as a linker-conjugate. The invention also relates to a process for the preparation of a bioconjugate, the process comprising the step of reacting a reactive group Q1 of a linker-conjugate according to the invention with a functional group F1 of a biomolecule. The... Synaffix B v

Process for the modification of a glycoprotein using a beta-(1,4)-n-acetylgalactosaminyl transferase or a mutant thereof

The present invention relates to a process for the modification of a glycoprotein, using a β-(1,4)-N-acetylgalactosaminyltransferase or a mutant thereof. The process comprises the step of contacting a glycoprotein comprising a glycan comprising a terminal GlcNAc-moiety, in the presence of a β-(1,4)-N-acetylgalactosaminyl-transferase or a mutant thereof, with anon-natural sugar-derivative nucleotide.... Synaffix B v

Process for the modification of a glycoprotein using a glycosyltransferase that is or is derived from a ß(1,4)-n-acetylgalactosaminyltransferase

The present invention relates to a process for the enzymatic modification of a glycoprotein. The process comprises the step of contacting a glycoprotein comprising a glycan comprising a terminal GlcNAc-moiety, in the presence of glycosyltransferase that is, or is derived from, a β-(1,4)-N-acetylgalactosaminyltransferase, with a non-natural sugar-derivative nucleotide. The non-natural... Synaffix B v

Sulfamide linker, conjugates thereof, and methods of preparation

Said compound may also be referred to as a linker-conjugate. The invention also relates to a process for the preparation of a bioconjugate, the process comprising the step of reacting a reactive group Q1 of a linker-conjugate according to the invention with a functional group F1 of a biomolecule. The... Synaffix B v

Process for the cycloaddition of a halogenated 1,3-dipole compound with a (hetero)cycloalkyne

The present invention relates to a cycloaddition process comprising the step of reacting a halogenated aliphatic 1,3-dipole compound with a (hetero)cycloalkyne according to Formula (1): Preferably, the (hetero)cycloalkyne according to Formula (1) is a (hetero)cyclooctyne. The invention also relates to the cycloaddition products obtainable by the process according to the... Synaffix B v

Process for the attachment of a galnac moiety comprising a (hetero)aryl group to a glcnac moiety, and product obtained thereby

The present invention relates to a process for attaching an N-acetylgalactosamine-(hetero)arylmoiety to an N-acetylglucosaminemoiety, the process comprising the step of contacting the N-acetylgalactosamine-(hetero)arylmoiety with the N-acetylglucosaminemoiety in the presence of a mutant galactosyltransferase, wherein the N-acetylglucosaminemoiety is according to Formula (1) the N-acetylgalactosamine-(hetero)arylmoiety is according to Formula (2): In a... Synaffix B v

Process for the cycloaddition of a hetero(aryl) 1,3-dipole compound with a (hetero)cycloalkyne

and wherein the (hetero)cycloalkyne is a (hetero)cyclooctyne or a (hetero)cyclononyne according to Formula (1). The invention also relates to the products obtainable by the process according to the invention.... Synaffix B v








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