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Synthetic Genomics Inc patents


Recent patent applications related to Synthetic Genomics Inc. Synthetic Genomics Inc is listed as an Agent/Assignee. Note: Synthetic Genomics Inc may have other listings under different names/spellings. We're not affiliated with Synthetic Genomics Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "S" | Synthetic Genomics Inc-related inventors


Expression of modified glycoproteins and glycopeptides

The present invention provides recombinant cells that contain a modification causing altered expression or function of at least one mannosyl transferase enzyme. As a result of the modification the cells produce a glycoprotein or glycopeptide that has an n-linked glycan profile that is simplified or humanized. ... Synthetic Genomics Inc

Generation of synthetic genomes

Methods for generating synthetic genomes, for example synthetic genomes having desired properties or viable genomes of reduced size, are disclosed. Also disclosed are synthetic genomes produced by the methods disclosed herein and synthetic cells containing the synthetic genomes disclosed herein.. ... Synthetic Genomics Inc

Recombinant virus replicon systems and uses thereof

The present disclosure generally relates to viral-based expression systems suitable for the production of molecules of interest. The disclosure relates to nucleic acid constructs, such as expression vectors, containing a modified replicon rna which includes a modified 5′-unstranslated region (5′-utr) and, optionally, at least some of its original viral sequence encoding structural proteins having been deleted. ... Synthetic Genomics Inc

Genetically engineered vibrio sp. and uses thereof

The present disclosure provides engineered vibrio sp. Organisms. ... Synthetic Genomics Inc

Materials and methods for the synthesis of error-minimized nucleic acid molecules

The present invention provides materials and methods useful for error correction of nucleic acid molecules. In one embodiment of the invention, a first plurality of double-stranded nucleic acid molecules having a nucleotide mismatch are fragmented by exposure to a molecule having unidirectional mismatch endonuclease activity. ... Synthetic Genomics Inc

Tamper resistant assembly for securing valuable material

The invention provides a tamper resistant assembly that that securely contains a valuable material. The assembly has a container for holding the valuable material, an optional carrier that contains the container, one or more cover components that enclose the valuable material in the container, and one or more labels having a plurality of devices that reveal tampering by distortion of at least one of the plurality of devices. ... Synthetic Genomics Inc

Influenza virus reassortment

New influenza donor strains for the production of reassortant influenza a viruses are provided.. . ... Synthetic Genomics Inc

Digital to biological converter

The present invention provides a system for receiving biological sequence information and activating the synthesis of a biological entity. The system has a receiving unit for receiving a signal encoding biological sequence information transmitted from a transmitting unit. ... Synthetic Genomics Inc

Production of proteins in labyrinthulomycetes

The present invention provides recombinant host cells that produce proteins or therapeutic proteins, and nucleic acid constructs for producing the cells. The cells have nucleic acid constructs that encode a heterologous protein, for example an antibody. ... Synthetic Genomics Inc

Synthesis of sequence-verified nucleic acids

The invention relates to methods and devices for preparing synthetic nucleic acids.. . ... Synthetic Genomics Inc

Programmable oligonucleotide synthesis

The invention relates to methods and devices for preparing synthetic nucleic acids.. . ... Synthetic Genomics Inc

In vitro recombination method

The present invention relates, e.g., to in vitro method, using isolated protein reagents, for joining two double stranded (ds) dna molecules of interest, wherein the distal region of the first dna molecule and the proximal region of the second dna molecule share a region of sequence identity, comprising contacting the two dna molecules in a reaction mixture with (a) a non-processive 5′ exonuclease; (b) a single stranded dna binding protein (ssb) which accelerates nucleic acid annealing; (c) a non strand-displacing dna polymerase; and (d) a ligase, under conditions effective to join the two dna molecules to form an intact double stranded dna molecule, in which a single copy of the region of sequence identity is retained. The method allows the joining of a number of dna fragments, in a predetermined order and orientation, without the use of restriction enzymes.. ... Synthetic Genomics Inc

Protein rich food ingredient from biomass and methods of preparation

The present invention provides a protein material and food ingredient from a sustainable and stable source. The sustainable and stable source of the food or food ingredient is biomass, for example an algal or microbial biomass. ... Synthetic Genomics Inc

Protein containing material from biomass and methods of production

The present invention provides methods and protein compositions having advantageous properties, such as a high uncorrected limiting amino acid score as well as favorable amounts of essential amino acids, branched chain amino acids, as well as other amino acids more difficult to find in the regular diet. The protein composition is obtainable as taught herein from algal or microbial biomass. ... Synthetic Genomics Inc

07/06/17 / #20170191094

Expression of type i fatty acid synthase genes in eukaryotic algae

The present invention provides recombinant algae expressing exogenous type i fatty acid synthase (fas) genes and demonstrating higher rates of fatty acid synthesis with respect to control microorgansims. The recombinant algae are able to produce greater amounts of fame lipids under nitrogen replete conditions.. ... Synthetic Genomics Inc

06/01/17 / #20170152520

Compositions and methods for expressing genes in algae

The present application provides novel regulatory elements including promoter sequences from microorganisms. The application further discloses dna constructs containing these novel regulatory elements, and recombinant microorganisms comprising these regulatory elements. ... Synthetic Genomics Inc

05/11/17 / #20170130238

Device and methods for biolistic transformation

The present invention provides an innovate method and device for depositing coated particles to prepare sample cartridges for use in a gene gun. It allows for scalability of sample cartridge preparation, as well as the ability to prepare multiple different samples simultaneously thereby reducing the time required to prepare different samples and consequently the time required to perform a biological assay, such as a transformation as. ... Synthetic Genomics Inc

05/04/17 / #20170121742

Algal mutants with increased lipid productivity

The present invention provides mutant microorganism that have higher lipid productivity than the wild type microorganisms from which they are derived while producing biomass at levels that are at least 45% of wild type biomass productivity under nitrogen replete conditions. Particular mutants produce at least 50% as much fame lipid as wild type while producing at least the amount of biomass produced by wild type cells under nitrogen replete conditions. ... Synthetic Genomics Inc

04/27/17 / #20170114107

Enhanced productivity by attenuation of chlorophyll binding protein genes

Mutant photosynthetic algae having increased biomass productivity are provided. The mutants have attenuated expression of violaxanthin chlorophyll a binding proteins (vcp) or fucoxanthin chlorophyll a/c binding proteins (fcp), reduced chlorophyll, higher apparent etr(ii), little to no reduction in pmax per cell, and decreased npq over a wide range of light intensities. ... Synthetic Genomics Inc

03/30/17 / #20170088865

Compositions and methods for producing chemicals and derivatives thereof

The present invention provides methods for producing a product of one or more enzymatic pathways. The pathways used in the methods of the invention involve one or more conversion steps such as, for example, an enzymatic conversion of guluronic acid into d-glucarate (step 7); an enzymatic conversion of 5-ketogluconate (5-kga) into l-iduronic acid (step 15); an enzymatic conversion of l-iduronic acid into idaric acid step 7b); and an enzymatic conversion of 5-ketocluconate into 4,6-dihydroxy 2,5-diketo hexanoate (2,5-ddh) (step 16). ... Synthetic Genomics Inc

03/16/17 / #20170073695

Compositions and methods for high efficiency in vivo genome editing

The present invention provides cell lines for high efficiency genome editing using cas/crispr systems, methods of generating such cells lines, and methods of generating mutations in the genome of an organism using such cell lines.. . ... Synthetic Genomics Inc

03/09/17 / #20170067069

Microorganisms engineered for increased productivity

The application provides recombinant microorganisms with increased productivity with respect to control or wildtype microorganisms. The recombinant microorganisms can include a non-native gene encoding a skp1 polypeptide or a chord-derived polypeptide. ... Synthetic Genomics Inc

03/02/17 / #20170058303

Microorganisms having increased lipid productivity

The present invention provides mutant microorganism that have higher lipid productivity than the wild type microorganisms from which they are derived while biomass at levels that are within approximately 50% of wild type biomass productivities under nitrogen replete conditions. Particular mutants produce at least twice as much fame lipid as wild type while producing at least 75% of the biomass produced by wild type cells under nitrogen replete conditions. ... Synthetic Genomics Inc

02/23/17 / #20170050944

Synthesis of fdca and fdca precursors from gluconic acid derivatives

The present invention provides methods of method of synthesizing 2,5-furan dicarboxylic acid (fdca) and fdca precursor molecules. The methods involve performing a chemical dehydration reaction on a gluconic acid derivative in the presence of a dehydration catalyst. ... Synthetic Genomics Inc

02/16/17 / #20170044555

Recombinant rna particles and methods of producing proteins

The present invention provides compositions and methods for the production and delivery of recombinant double-stranded rna molecules (dsrna) encoding heterologous proteins, which can be useful for various therapeutic purposes as well as for the production of desired proteins. The compositions contain engineered double-stranded rna particles (dsrps) that can contain a double-stranded rna molecule that can be a genome or portion of a genome, which can be enclosed in a capsid or coat protein. ... Synthetic Genomics Inc

01/26/17 / #20170020159

Protein rich food ingredient from biomass and methods of preparation

The present invention provides a protein material and food ingredient from a sustainable and stable source. The sustainable and stable source of the food or food ingredient is biomass, for example an algal or microbial biomass. ... Synthetic Genomics Inc








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