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Texas Tech University System patents


Recent patent applications related to Texas Tech University System. Texas Tech University System is listed as an Agent/Assignee. Note: Texas Tech University System may have other listings under different names/spellings. We're not affiliated with Texas Tech University System, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "T" | Texas Tech University System-related inventors


 new patent  Microfluidic device for studying nematodes

A microfluidic device includes a substrate, a cover layer and one or more chambers disposed within the cover layer, the substrate or both. Each chamber has a first end, a second end, and a set of micro-pillars disposed therein. ... Texas Tech University System

 new patent  Inhibitors of mcl-1 as drugs to overcome resistance to braf inhibitors and mek inhibitors

The present invention includes compositions and methods for inhibiting mcl-1, including novel inhibitors of mcl-1, and compositions and methods for treating a subject with cancer that is refractory to one or more mapk pathway protein inhibitors.. . ... Texas Tech University System

Child mobility device

A toddler mobility system and apparatus comprising a chassis, two casters attached to the front of the chassis, two wheels attached to a rear of the chassis, a first motor operably connected to one of the at least two wheels, a second motor operably connected to another of the at least two wheels, a battery configured to supply power to the motors, a body affixed to the chassis and covering the chassis, the body further comprising an integrated seat, an integrated backrest, a control system wherein the control system further comprises a microcontroller operably connected to a joystick, and a motor controller that receives control input from the microcontroller and adjusts power to the first motor and the second motor independently, wherein the toddler mobility system is configured for users weighing 50 pounds or less.. . ... Texas Tech University System

Serotype discrimination biomarkers to distinguish infantis from heidelberg and newport from hadar

The present invention provides a set of oligonucleotides to screen for the presence of targeted salmonella serotypes in enrichment or to characterize presumptive colonies. The set of oligonucleotides includes at least one set of primers and probe for the detection of salmonella serotype selected from newport, heidelberg, infantis, and hadar and to discriminate between. ... Texas Tech University System

Media compositions for promoting bacterial and fungal growth

Methods and compositions for enhancing or promoting germination of bacterial spores, and yeasts are disclosed herein. The composition of the present invention comprises an extract obtained from banana or any member belonging to the genus musa that may be used alone or in a growth medium to promote and enhance germination of bacterial spores, growth of bacterial, yeast, and fungal cell cultures.. ... Texas Tech University System

Novel method for producing hollow shells from pollen grains

The present invention includes methods of making a hollow exine shell from pollen grains comprising the steps of: providing a plant pollen or spore; extracting organic matter from the plant pollen or spore with an organic solvent; after the organic extraction treating the plant pollen or spore with an acid solution; after the acid treatment treating the plant pollen or spore with an alkali solution; and isolating the plant pollen or spore, wherein the pollen or spore have open apertures on pollens with visible apertures that open to the interior hollow cavity, wherein the same apertures are closed in naturally occurring pollens.. . ... Texas Tech University System

Ankle (tibio-talar) fusion nail

The present invention includes a tibio-talar device and a method for providing stabilizing support between a tibia and a talus comprising: a bone nail adapted to traverse the talus and the tibia, wherein the bone nail is curved such that it traverses the talus and enters the tibia at an angle, wherein the nail is angled from side to side, wherein the bone nail is configured to provide for intra medullary fusion of the ankle without obstructing the subtalar joint. The nail is introduced from talus and curves to pass to the tibia fusing the ankle joint.. ... Texas Tech University System

Ude-based robust droop control for parallel inverter operation

A control system and method include a control strategy and a ude (uncertainty and disturbance estimator)-based controller incorporated into the control strategy to achieve proportional load sharing for parallel-operated inverters. The ude-based controller regulates the reactive power against the output generated by a reactive power reference unit according to the load voltage to generate the amplitude of the control voltage. ... Texas Tech University System

System and method for non-contact interaction with mobile devices

Disclosed is a system and method for controlling handheld devices without contact by interacting with their wireless charging coils or other inductive coil antennae. The present disclosure utilizes the interaction between human body and the coil wherein the coil is used to send alternating magnetic field to interact with a control signal, such as a hand, instead of simply using the coil in the smart phone as a power receiver. ... Texas Tech University System

Phenotypic high-content assay to evaluate drugs

The present invention includes a high throughput screen for an active agent for the treatment of comprising: plating cells at least one pathophysiologically relevant mislocated mutant form of a peroxisomal enzyme; adding a control and compound to each plate from a library of compounds; fixing the cells; contacting the cells with an agent that detects the mislocated mutant form of a peroxisomal enzyme; and imaging the cells in the wells.. . ... Texas Tech University System

Magnetic field vector imaging array

Methods and systems for imaging a magnetic field as vectors (or scalars if desired) in either two or three dimensions without the need for rastering or relative motion between the sensors and the magnetic field being viewed. A secondary function is to image electric current flow as vectors. ... Texas Tech University System

Surface modification of zero valent iron material for enhanced reactivity for degrading chlorinated contaminants in water

Methods, systems, and compounds for degrading chlorinated compounds in water. A facile aqueous-based surface treatment of zero-valent iron is provided to increase the reactivity of a zero-valent iron material for degrading chlorinated compounds in the water without the use of a noble metal catalyst. ... Texas Tech University System

High-throughput fabrication of patterned surfaces and nanostructures by hot-pulling of metallic glass arrays

The present invention includes composition and methods for the fabrication of very-high-aspect-ratio structures from metallic glasses. The present invention provides a method for nondestructive demolding of templates after thermoplastic molding of metallic glass features.. ... Texas Tech University System

Texas Tech University System

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10/26/17 / #20170307611

Microdevice for cell separation utilizing activation phenotype

Disclosed is a system and method for a microdevice to separate blood cells based on differences in antigen expression. Specifically, cells of the same phenotype are separated based on whether or not they are activated during infection or resting. ... Texas Tech University System

10/05/17 / #20170283413

Cancer treatment utilizing sp-141 to bind with mdm2 and act as an inhibitor of mdm2 expression

An sp-141 compound is a novel small molecule that can serve as a molecular-targeted chemotherapeutic agent. In one embodiment, the labeled compound can comprise sp-141, which comprises 6-methoxy-1-(naphthalen-1-yl)-9 h-pyrido[3,4-b]indote. ... Texas Tech University System

10/05/17 / #20170281545

Immunomodulation using spores and pollen grains

The present invention includes compositions, methods of making and using the compositions for modulating the immune response in a subject by providing a vaccine composition having a pollen or spore disposed in a pharmaceutical carrier for delivery to a subject, wherein the pollen or spore comprises multiple pores that connect an outer surface of the pollen/spore to an inner cavity and one or more antigens disposed on the outer surface, in the inner cavity, in the multiple pores, or a combination thereof, wherein the one or more antigens modulate an immune responses in the subject.. . ... Texas Tech University System

09/21/17 / #20170268044

Molecular discrimination of regulated and non-regulated salmonella serotypes

The present invention provides a set of oligonucleotides to screen for the presence of targeted salmonella serotypes in an enrichment or to characterize presumptive colonies. The set of oligonucleotides includes at least one set of primers and probe for the detection of salmonella serotype selected from typhimurium, enteritidis, newport, heidelberg, infantis, virchow and hadar. ... Texas Tech University System

09/21/17 / #20170267968

Methods and devices to control fluid volumes, reagent and particle concentration in arrays of microfluidic drops

A microfluidic device includes a substrate comprising an inlet in fluid communication with one or more conduits and one or more parking loops in fluid communication with the one or more conduits. Each parking loop includes a bypass channel and a lower branch with a fluidic trap capable of retaining one or more drops of a sample solution, wherein the bypass channel has a smaller hydrodynamic resistance than the lower branch within the fluidic trap and a hydrodynamic resistance ratio (rt/rb) between the lower branch within the fluidic trap and the bypass channel is from 1.5 to 3.2. ... Texas Tech University System

09/14/17 / #20170259267

Integrated microfluidic rectifier for various bioanalytical applications

A device for performing a microfluidic assay on a chip comprising, a microfluidics chip, one or more fluid receptacles on the chip for receiving a fluid, a plurality of pneumatic pumps arrayed on the chip, each pump having a discharge channel leading to a rectifier on the chip, and a reaction chamber in fluid communication with each of the rectifiers, wherein a pressure on the pressurized fluid source drives fluid from the fluid receptacle into the incoming fluid channel connecting the fluid receptacle to the pump, through the pump and into the discharge channel, through the discharge channel to the rectifier, and through the rectifier into the reaction chamber, wherein the pump is configured to generate droplets of a pre-determined size, wherein the rectifiers prevent backflow of the droplets, and wherein droplets are combined in the reaction chamber, the chamber facilitating an assay being performed on the chip.. . ... Texas Tech University System

09/07/17 / #20170253636

Dual purpose universal influenza vaccine confers protective immunity against anthrax

The present invention includes antigenic fusion proteins, nucleic acids encoding the fusion proteins and methods of making and using the same, wherein the fusion protein comprises three or more different influenza a ectodomains of matrix protein 2 (m2e); one or more stem regions of an influenza a hemagglutinin 2 (ha2) protein; and optionally an anthrax antigen, wherein the fusion protein is immunogenic across strains.. . ... Texas Tech University System

08/24/17 / #20170240899

Multiplexed shrnas and uses thereof

Nucleic acid molecules such as shrna clusters and artificial mirna clusters are disclosed, also disclosed are methods of use, compositions, cells, viral particles, and kits relating to the nucleic acid molecules disclosed herein. The disclosure provides, at least in part nucleic acid molecules such as shrna clusters encoding shrna-like molecules and artificial mirna clusters encoding modified pri-mirna-like molecules. ... Texas Tech University System

08/17/17 / #20170232097

Live attenuated viral vaccine created by self-attenuation with species-specific artificial microrna

The present invention includes a live attenuated virus and methods of making the same comprising an isolated virus comprising a viral genome that expresses one or more viral antigens; and one or more exogenous species-specific micrornas inserted into the viral genome and expressed thereby, wherein the species-specific micrornas are ubiquitously expressed in a viral target species cell but not in a viral propagation cell.. . ... Texas Tech University System

08/03/17 / #20170218397

Conditional cytotoxic gene therapy vector for selectable stem cell modification for anti hiv gene therapy

A method, system, and apparatus for treating a patient with hiv. A vector can be modified from a thymidine kinase gene. ... Texas Tech University System

07/20/17 / #20170203065

Self-deployed cuff and skirt tracheal tube

A method and system for an endotracheal tube or tracheostomy a tube formed with a hole, a cuff connected to the tube and formed around the hole, and a skirt connected to the tube above the cuff and draped over the cuff. A coating of a hydrophobic, lipophobic, and oleophobic substance can be disposed on the interior and exterior surface of the tube, the cuff, and the skirt. ... Texas Tech University System

07/13/17 / #20170196836

Lung cancer adjuvant therapy

The present invention includes compositions and methods for the treatment of cancer comprising an antineoplastic drug and an inhibitor of chromosome maintenance region 1 (crm1) protein expression or activity, wherein the inhibitor of crm1 enhances the anti-neoplastic effect of the antineoplastic drug.. . ... Texas Tech University System

06/08/17 / #20170159416

Method for optimization of huff-n-puff gas injection in shale reservoirs

Methods for optimization of liquid oil production by huff-n-puff in shale reservoirs to achieve an improved (and optimal) oil recovery factor. The process determines and utilizes the optimum huff and puff times, number of cycles and soaking time under practical operation and reservoir conditions. ... Texas Tech University System

05/18/17 / #20170140848

Cotton fiber dissolution and regeneration and 3d printing of cellulose based conductive composites

The present invention includes composition and methods for a core matrix comprising a dissolved cellulose fiber of, e.g., high molecular weight (dp>5000) or microcrystalline cellulose of low molecular weight (dp: 150-300), printed into a two or three dimensional pattern; a conductive material comprising a carbon nanotube or graphene oxide disposed on or about the cellulose fiber or microcrystalline cellulose; and an enhancer or stabilizer that stabilizes the dissolved cellulose or microcrystalline cellulose disrupted during a printing process, wherein the conductive material and the cellulose or microcrystalline cellulose forms one or more features in or on the cellulose fiber or microcrystalline cellulose.. . ... Texas Tech University System

05/18/17 / #20170136100

Thioredoxin or thioredoxin derivatives or peptides for the treatment of high blood pressure

The present invention provides methods and compositions for the treatment of cardiovascular disorders comprising: a therapeutically effective amount of thioredoxin-1 or a thioredoxin-1 derivative in a pharmaceutical carrier to ameliorate one or more symptom of a cardiovascular disorder.. . ... Texas Tech University System

05/04/17 / #20170122086

Liquid oil production from shale gas condensate reservoirs

A process of producing liquid oil from shale gas condensate reservoirs and, more particularly, to increase liquid oil production by huff-n-puff in shale gas condensate reservoirs. The process includes performing a huff-n-puff gas injection mode and flowing the bottom-hole pressure lower than the dew point pressure.. ... Texas Tech University System

04/13/17 / #20170102457

Hybrid fmcw-intererometry radar for positioning and monitoring and methods of using same

Disclosed is a system and method for a hybrid radar system that integrates frequency-modulated continuous wave (fmcw) mode and interferometry mode. The radar works as a time division system that continuously switches between the fmcw mode and interferometry mode. ... Texas Tech University System

03/30/17 / #20170091878

Method and system for controlling charge and discharge of high powered energy storage systems

A modeling framework performs an economic analysis of a battery storage system to determine the economic feasibility with different business opportunities. The installed battery system can be utilized to optimize the energy flow between the wind farm and the utility. ... Texas Tech University System

03/23/17 / #20170083688

Apparatus and computerized method for optimizing or generating a sigma profile for a molecule

An apparatus and computerized method optimizes or generates a sigma profile for a molecule by receiving a sigma profile for the molecule, calculating an activity coefficient for the molecule using the sigma profile for the molecule, calculating a solubility for the molecule using the activity coefficient for the molecule, optimizing or adjusting the sigma profile for the molecule by adjusting the sigma profile using an objective function and one or more constraints, providing the sigma profile to an output device communicably coupled to a processor.. . ... Texas Tech University System

03/23/17 / #20170080071

Composition and method for diagnosis and immunotherapy of lung cancer

The present invention includes compositions and methods for the diagnosis and treatment of lung cancer with a recombinant tumor-associated antigen loaded antigen presenting cell that generates a cytotoxic t lymphocyte specific immune response to at least one of sp17, akap-4, or pttg1 expressed by one or more lung cancer cells.. . ... Texas Tech University System








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



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