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The Broad Institute Inc
The Broad Institute Inc_20131212
  

The Broad Institute Inc patents

Recent patent applications related to The Broad Institute Inc. The Broad Institute Inc is listed as an Agent/Assignee. Note: The Broad Institute Inc may have other listings under different names/spellings. We're not affiliated with The Broad Institute Inc, we're just tracking patents.

ARCHIVE: New 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "T" | The Broad Institute Inc-related inventors




Date The Broad Institute Inc patents (updated weekly) - BOOKMARK this page
10/05/17Protected guide rnas (pgrnas)
09/21/17High-throughput assembly of genetic elements
09/14/17Propeptide-luciferase fusion proteins and methods of use thereof
08/24/17Compositions and methods for identifying and treating cachexia or pre-cachexia
08/10/17Uses of salt-inducible kinase (sik) inhibitors
08/10/17Compositions and methods of treating muscular dystrophy
08/03/17Inhibitors of histone deacetylase
07/27/17Novel crispr enzymes and systems
07/13/17Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation
07/06/17Crispr-cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
06/22/17Crispr-cas altering expression of gene products
06/22/17Genome editing using cas9 nickases
06/15/17Inducible dna binding proteins and genome perturbation tools and applications thereof
06/01/17Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
04/27/17Compositions and methods for targeting cancer-specific sequence variations
04/20/17Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
02/23/17Cancer-related extracellular matrix signatures and related methods and products
02/23/17Method for label-free image cytometry
02/02/17Systems and methods for droplet tagging
02/02/17Ribosomal ribonucleic acid hybridization for organism identification
02/02/17Ddr2 mutations in squamous cell lung cancer
01/19/17Compounds for the treatment of mycobacterial infections
12/29/16T cell balance gene expression, compositions of matters and methods of use thereof
12/29/16Uses of paralog-selective inhibitors of gsk3 kinases
12/22/16Compositions and methods for sensitizing a neoplastic cell to radiation
12/08/16Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
12/08/16Engineering of systems, methods and optimized guide compositions with new architectures for sequence manipulation
12/08/16Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
12/08/16Systems, methods and compositions for sequence manipulation with optimized functional crispr-cas systems
12/01/16Inhibitors of histone deacetylase
11/24/16Crispr-cas systems, crystal structure and uses thereof
11/24/16Delivery, use and therapeutic applications of the crispr-cas systems and compositions for genome editing
11/24/16Knock-in rodent comprising a mutation in an endogenous crbn locus and methods of use thereof
11/24/16Engineering of systems, methods and optimized guide compositions for sequence manipulation
11/10/16Compositions and methods for diagnosing, evaluating and treating cancer
11/03/16Delivery, use and therapeutic applications of the crispr-cas systems and compositions for hbv and viral diseases and disorders
10/27/16Formulations for neoplasia vaccines
10/20/16Enhanced methods of ribonucleic acid hybridization
10/20/16Compositions and methods for identifying and treating cachexia or pre-cachexia
10/13/16Kynurenine pathway biomarkers predictive of anti-immune checkpoint inhibitor response
10/13/16Polymorphic gene typing and somatic change detection using sequencing data
10/13/16Kynurenine pathway biomarkers predictive of anti-immune checkpoint inhibitor response
10/06/16Compounds and methods for the treatment of malaria
09/29/16Crispr-cas altering expression of gene products
09/29/16Compositions and methods for selecting a treatment for b-cell neoplasias
09/22/16Functional genomics using crispr-cas systems, compositions, methods, screens and applications thereof
09/15/16Spatial and cellular mapping of biomolecules in situ by high-throughput sequencing
09/01/16Functional genomics using crispr-cas systems, compositions, methods, screens and applications thereof
09/01/16Inhibitors of histone deacetylase
08/25/16Artificial transcription factors comprising a sliding domain and uses thereof
08/11/16Modified saponins for the treatment of fungal infections
07/28/16Sieve valves, microfluidic circuits, microfluidic devices, kits, and methods for isolating an analyte
07/21/16Novel crispr enzymes and systems
07/21/16Methods for shearing and tagging dna for chromatin immunoprecipitation and sequencing
07/07/16Methods of determining multiple interactions between nucleic acids in a cell
06/30/16Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation
06/23/16Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using viral components
06/16/16Oncogenic models based on delivery and use of the crispr-cas systems, vectors and compositions
06/02/16Delivery, engineering and optimization of systems, methods and compositions for targeting and modeling diseases and disorders of post mitotic cells
06/02/16Delivery and use of the crispr-cas systems, vectors and compositions for hepatic targeting and therapy
06/02/16Optimized crispr-cas double nickase systems, methods and compositions for sequence manipulation
06/02/16Compounds for the treatment of malaria
05/26/16Compounds and compounds for use in methods for treating diseases or conditions mediated by protein disulfide isomerase
05/05/16High-throughput rna-seq
05/05/16Accurate typing of hla through exome sequencing
Patent Packs
04/28/16Crispr-cas component systems, methods and compositions for sequence manipulation
04/28/16Crispr-cas component systems, methods and compositions for sequence manipulation
04/28/16Reprogrammed cells and methods of production and use thereof
04/28/16Compositions and methods for detecting and treating glioblastoma
04/14/16Compositions and methods for personalized neoplasia vaccines
04/14/16Compounds and methods for the treatment of isocitrate dehydrogenase related diseases
03/31/16Markers for ezh2 inhibitors
03/24/16Novel hybridization probes and uses thereof
03/17/16Amyloid precursor protein mrna blockers for treating down sydnrome and alzheimer's disease
03/10/16Recombinant virus and preparations thereof
03/10/16Methods for quantitating dna using digital multiple displacment amplification
03/03/16Compounds, substrates and methods related to histone deacetylases
03/03/16Sle and sle-related disease-associated risk markers and uses thereof
02/11/16Methods for the detection of dna-rna proximity in vivo
02/11/16Selective purification of rna and rna-bound molecular complexes
Patent Packs
02/04/162-aaa as a biomarker and therapeutic agent for diabetes
02/04/16Compounds for inducing proliferation and differentiation of cells, and methods of use thereof
02/04/16Compounds for the treatment of tuberculosis
02/04/16Substituted aminothiazoles for the treatment of tuberculosis
02/04/16Microfluidic microbe detection and isolation
02/04/16Ribosomal ribonucleic acid hybridization for organism identification
02/04/16Mast cell cancer-associated germ-line risk markers and uses thereof
01/28/16Massively multiplexed rna sequencing
01/28/16Osteosarcoma-associated risk markers and uses thereof
01/28/16Methods of identifying responses to map kinase inhibition therapy
01/28/16Visual workflow display and management
01/21/16Compounds and compositions for the treatment of cancer
01/07/16Systems and methods for identifying significantly mutated genes
12/31/15Methods for assessing the risk of canine atopic dermatitis
12/24/15Dendritic cell response gene expression, compositions of matters and methods of use thereof
12/17/15T cell balance gene expression, compositions of matters and methods of use thereof
12/10/15Methods, models, systems, and identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof
12/10/15Indazole derivatives and uses thereof
11/26/15Treatment and prognosis of lymphangioleiomyomatosis
11/05/15Kinase inhibitors and methods of use thereof
10/22/15Cancer-associated germ-line and somatic markers and uses thereof
10/15/15Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
10/15/15Inducible dna binding proteins and genome perturbation tools and applications thereof
10/08/15Heterocycle-bisamide inhibitors of scavenger receptor bi
09/24/15Compositions and methods for labeling of agents
09/17/15High-throughput dynamic reagent delivery system
09/17/15Thiohydantoin derivatives and uses thereof
09/17/15Compositions and methods for long insert, paired end libraries of nucleic acids in emulsion droplets
09/10/15Methods of diagnosing and treating medullary cystic kidney disease
09/03/15Engineering of systems, methods and optimized guide compositions for sequence manipulation
Social Network Patent Pack
08/20/15Engineering of systems, methods and optimized guide compositions for sequence manipulation
08/20/15Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components
08/06/15Modulators of hepatic lipoprotein metabolism
07/30/15Molecular sleds and uses thereof
07/30/15Neuropsychiatric disorder-associated mutations and uses thereof
07/23/15Crispr-cas altering expression of gene products
07/23/15Methods for generating pools of variants of a dna template
07/23/15Methods of diagnosing infectious disease pathogens and their drug sensitivity
07/16/15Methods and analyzing and quantifying dna alterations in cancer
07/09/15Inhibitors of histone deacetylase
Patent Packs
07/02/15Crispr-cas altering expression of gene products
07/02/15Modified saponins for the treatment of fungal infections
06/25/15Diagnostic and treatment methods in subjects having or at risk of developing resistance to cancer therapy
06/25/15Detecting variants in sequencing data and benchmarking
05/28/15Methods and devices for tuberculosis diagnosis using biomarker profiles
05/21/15Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy
03/26/15Cancer-related extracellular matrix signatures and related methods and products
03/19/15Crispr-cas component systems, methods and compositions for sequence manipulation
02/26/15Compositions and methods for sensitizing a neoplastic cell to radiation
02/12/15Multiplex methods to assay mixed cell populations simultaneously
01/29/15Crispr-cas component systems, methods and compositions for sequence manipulation
01/15/15Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
01/01/15Compositions, kits, and methods for the identification, assessment, prevention, and therapy of cancer
12/18/14Device and fragmenting polymers and particles
11/27/14Methods of treating cancer
11/13/14Fluorescent substrates for determining lysine modifying enzyme activity
10/02/14Compounds for the treatment of mycobacterial infections
09/18/14Novel solid forms of tacedinaline
09/11/14Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
08/28/14Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
08/28/14Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation
08/28/14Compositions and methods for co-amplifying subsequences of a nucleic acid fragment sequence
08/21/14Crispr-cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
07/17/14Multiplexed genetic reporter assays and compositions
07/03/14Methods, systems, and identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof
06/26/14Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
06/26/14Crispr-cas component systems, methods and compositions for sequence manipulation
06/19/14Crispr-cas altering expression of gene products
04/17/14Kinase inhibitors and methods of use thereof
04/10/14Compounds and methods for the treatment of isocitrate dehydrogenase related diseases
Patent Packs
02/13/14Small molecule inhibitors for treating parasitic infections
01/30/14Paired end bead amplification and high throughput sequencing
12/12/13Compounds and methods for treating diseases mediated by protease activated receptors
11/28/13Compounds and methods for treating autoimmune diseases
10/03/13Prediction of and monitoring cancer therapy response based on gene expression profiling
09/05/13Hybrid selection using genome-wide baits for selective genome enrichment in mixed samples
06/13/13Nucleotide-specific recognition sequences for designer tal effectors
06/13/13Nucleotide-specific recognition sequences for designer tal effectors
06/13/13Novel solid forms of tacedinaline
05/30/13Nucleotide-specific recognition sequences for designer tal effectors
05/30/13Nucleotide-specific recognition sequences for designer tal effectors
04/25/13Novel solid forms of tacedinaline
12/12/13Compounds and methods for treating diseases mediated by protease activated receptors







ARCHIVE: New 2017 2016 2015 2014 2013 2012 2011 2010 2009



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