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The California Institute For Biomedical Research patents


Recent patent applications related to The California Institute For Biomedical Research. The California Institute For Biomedical Research is listed as an Agent/Assignee. Note: The California Institute For Biomedical Research may have other listings under different names/spellings. We're not affiliated with The California Institute For Biomedical Research, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "T" | The California Institute For Biomedical Research-related inventors


Small molecule inhibitors of fibrosis

Described herein are compounds and compositions for the treatment of a fibrotic disease.... The California Institute For Biomedical Research

Methods of constructing amino terminal immunoglobulin fusion proteins and compositions thereof

Disclosed herein are immunoglobulin fusion proteins comprising a first immunoglobulin region attached to a therapeutic peptide at the amino terminus of the immunoglobulin region. The immunoglobulin fusion proteins may further comprise a second immunoglobulin region. The immunoglobulin fusion protein may further comprise one or more connecting peptides, linkers, proteolytic cleavage... The California Institute For Biomedical Research

Peptidic chimeric antigen receptor t cell switches and uses thereof

Disclosed herein are chimeric antigen receptor effector cells (CAR-ECs) and CAR-EC switches. The switchable CAR-ECs are generally T cells. The one or more chimeric antigen receptors may recognize a peptidic antigen on the CAR-EC switch. The CAR-ECs and switches may be used for the treatment of a condition in a... The California Institute For Biomedical Research

Small molecule inhibitors of fibrosis

Described herein are compounds and compositions for the treatment of a fibrotic disease.... The California Institute For Biomedical Research

Constant region antibody fusion proteins and compositions thereof

Disclosed herein are antibody fusion constructs and uses thereof. The antibody fusion construct may comprise an antibody fusion protein. The antibody fusion protein may comprise a non-antibody peptide inserted into an antibody portion of the antibody fusion protein. Alternatively, the antibody fusion construct may comprise a bispecific antibody. The bispecific... The California Institute For Biomedical Research

Elastase inhibitors

Described herein are compounds, compositions, and methods of their use for the treatment of a lung or intestinal disease.... The California Institute For Biomedical Research

Lpa receptor modulators for brown fat differentiation

Described herein is a method of increasing brown fat differentiation or increasing energy expenditure in a subject in need thereof, the method comprising administering to the subject an LPA receptor modulator, or a pharmaceutically acceptable salt, solvate, polymorph, prodrug, metabolite, deuteride, N-oxide, stereoisomer, or isomer thereof.... The California Institute For Biomedical Research

Auristatin-antibody conjugates and uses thereof

Disclosed herein are auristatin-antibody conjugates and compositions thereof. The auristatin-antibody conjugates and compositions may be used for treating diseases such as cancer. Also disclosed are methods of producing auristatin-antibody conjugates.... The California Institute For Biomedical Research

Targeting agent antibody conjugates and uses thereof

Methods, compositions and uses are provided for bispecific antibodies comprising one or more unnatural amino acids. The bispecific antibodies may bind to two or more different receptors, co-receptors, antigens, or cell markers on one or more cells. The bispecific antibodies may be used to treat a disease or condition (e.g.,... The California Institute For Biomedical Research








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