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The Methodist Hospital System
The Methodist Hospital

The Methodist Hospital patents


Recent patent applications related to The Methodist Hospital. The Methodist Hospital is listed as an Agent/Assignee. Note: The Methodist Hospital may have other listings under different names/spellings. We're not affiliated with The Methodist Hospital, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "T" | The Methodist Hospital-related inventors


Implantable nanochannel delivery devices

An implantable device comprising a nanochanneled membrane is described. The device uses nanofluidics to control the delivery of diagnostic and/or therapeutic agents intratumorally. ... The Methodist Hospital

Porous silicon microparticle-based cancer vaccines and methods for potentiating anti-tumor immunity

Porous silicon (psi) microparticles (psm) are disclosed, which provide an important advance in the area of cancer immunotherapeutics and molecular nanomedicine. In particular, potent psm-based adjuvants are disclosed for dendritic cell-based vaccines compositions, and methods for their use in a variety of cancer immunotherapies. ... The Methodist Hospital

Multiplexed volumetric bar chart chip for point of care biomarker and/or analyte quantitation, including competitive control

Apparatus for determining the quantity of a target analyte present in a sample, the apparatus comprising: a first plate comprising a plurality of recesses arranged to form a plurality of rows extending parallel to one another, and a plurality of channels extending perpendicularly to the plurality of rows of the first plate; and a second plate comprising a plurality of recesses arranged to form a plurality of rows extending parallel to one another, and a plurality of channels extending perpendicularly to the plurality of rows of the second plate; wherein the first plate and the second plate are assembled together so that the first plate is positioned against the second plate and the recesses of the first plate communicate with the recesses of the second plate so as to form a plurality of sample rows, a plurality of control rows, and an ink row disposed between the plurality of sample rows and the plurality of control rows.. . ... The Methodist Hospital

Cd38 ligand-drug conjugates for targeted cancer therapy

Disclosed are compositions and methods relating to nucleic acid aptamers that specifically target cd38 protein and also selective binding to cd38-expressing cells. The ligand-drug conjugates specifically target cd38-expressing cancer cells and subsequently internalize into the cell.. ... The Methodist Hospital

Cd117 ligand-drug conjugates for targeted cancer therapy

Disclosed are compositions and methods relating to nucleic acid aptamers that specifically target cd117 protein and also selective binding to cd117-expressing cells. The ligand-drug conjugates specifically target cd117-expressing cells and subsequently internalize into the cells, leading apoptosis, growth inhibition, and death of cells of interest and no off-target toxicity to ccd117-negative normal cells.. ... The Methodist Hospital

Methods and devices for sample characterization

Provided herein are methods and devices for the detection, quantification, and/or monitoring of characteristics in samples. The disclosed methods and devices can be used, for example, to identify the presence and location of atrial fibrillation indicators with high spatial resolution. ... The Methodist Hospital

Systems and methods for medical procedure monitoring

Systems and methods for monitoring medical procedures. Particular embodiment's relate to monitoring medical procedures performed in operating room environments through the use of various types of sensors, including for example, wireless electroencephalography (eeg) monitoring systems. ... The Methodist Hospital

Drug repositioning methods for targeting breast tumor initiating cells

Disclosed are systems biology-based methods for repositioning known pharmaceutical compounds to new indications, through the identification of network-based signatures. In particular, the invention provides new and useful methods for selecting drugs or combinations of drugs (and preferably previously-approved drugs) for use in new therapeutic indications. ... The Methodist Hospital

Single cell patterning and coordinated transfer of patterned cells

Apparatus for single cell patterning, the apparatus comprising: a structure comprising a surface channel formed therein, the surface channel being connected to an inlet and an outlet; and a cell trap disposed in the surface channel, the cell trap comprising a body defining a flow diverter for diverting flow passing by the cell trap into a wide path or a narrow path, and the body and the structure together defining a well for capturing a cell diverted by the flow diverter toward the narrow path.. . ... The Methodist Hospital

Methods for treating cancer using inos-inhibitory compositions

Disclosed are methods for treating one or more mammalian cancers, and in particular, methods for treating human melanoma, or a head or neck cancer, that employ therapeutically-effective amounts of one or more inos pathway-inhibitory compounds, either alone, or in combination with one or more selected antihypertensive agents (including, for example, calcium channel antagonists), alone, or further in combination with one or more conventional chemotherapeutic agents. Also disclosed are pharmaceutical formulations that comprise these compositions, as well as methods for their use in treating refractory, metastatic, and/or relapsed cancers, or, for use in the management or reversal of treatment resistance in one or more such mammalian cancers.. ... The Methodist Hospital

Non-invasive radiofrequency field treatment for cancer therapy

Embodiments of the disclosure concern methods and compositions for treating a subject with cancer, including overcoming resistance to a cancer drug using non-invasive radiotherapy frequency in combination with cancer drugs. In particular embodiments, radiofrequency therapy and cancer drugs in combination provide a synergistic benefit for cancer therapy. ... The Methodist Hospital

System and methods for quantitatively describing biophysical markers

Disclosed are method of detecting or characterizing a tumor by quantitatively measuring and comparing changes in mass transfer into the tumor and normal tissue over time using computed tomography or magnetic resonance imaging. The methods can be used to predict therapeutic response to treatment and to develop treatment plans.. ... The Methodist Hospital

Modular device for preventing compression and instability in a segmental defect repair scaffold

The present invention relates to a polymer scaffold design and method for treating segmental long bone defects without amputation that permits permanent regrowth of bone in the area of the segmental defect, without external fixation or other problems inherent in current systems. The polymer scaffold is preferably made from a poly(ester urea) polymer and includes an outer shell, sized to fit over a segmental defect in a bone, and a collagen containing material. ... The Methodist Hospital

Multivalent ligands targeting vegfr

Compounds that target vascular endothelial growth factor receptors for therapy and imaging are disclosed. Methods for making the compounds and detecting or imaging cells expressing vegfr using the compounds are also provided. ... The Methodist Hospital

03/16/17 / #20170072072

Ph sensitive fluorescent compounds and methods for tumor detection

Ph-sensitive fluorescent compounds that can generate a detectable signal for the relatively small changes in proton concentration associated with cancerous tissue are described. Methods of making and using the compounds to help detect cancerous tissue are also disclosed.. ... The Methodist Hospital

03/02/17 / #20170056327

Micro/nano composite drug delivery formulations and uses thereof

Disclosed are micro/nano composite drug delivery compositions for use in diagnosis, prophylaxis, treatment and/or amelioration of one or more symptoms of a mammalian disease, disorder, dysfunction, or abnormal condition. In illustrative embodiments, pharmaceutical formulations comprising these composites are provided that are useful in methods for targeting selected mammalian cells and tissues, particularly human lung tissue, and delivering one or more therapeutic agents, particularly in the treatment of human lung cancers, such as melanoma lung metastases.. ... The Methodist Hospital

02/16/17 / #20170042445

Method and apparatus for identifying the ureter during a minimally-invasive procedure

A method for identifying a ureter during a medical procedure, the method comprising: providing an electrical stimulator comprising: a shaft having at least one electrode; and a power supply connected to the at least one electrode for providing an electrical signal to the at least one electrode; advancing the shaft so that the at least one electrode contacts tissue; operating the power supply so that the electrical signal is applied to the tissue; and visually observing the tissue to determine the presence of a ureter in the tissue.. . ... The Methodist Hospital

01/26/17 / #20170020835

Inos-inhibitory compositions and their use as breast cancer therapeutics

Disclosed are methods for treating one or more mammalian cancers, and in particular, methods for treating human breast cancer employing one or more inos pathway-inhibitory compounds, either alone, or in combination with one or more selected antihypertensive agents, including calcium channel antagonists, either alone, and further in combination with one or more conventional chemotherapeutic or anti-cancer regimens. Also disclosed are particular therapeutic formulations including these compositions, and methods for their use in treating refractory, metastatic, and relapsed cancers, and for managing or reversing treatment resistance in human triple-negative breast cancers in particular.. ... The Methodist Hospital








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This listing is an abstract for educational and research purposes is only meant as a recent sample of applications filed, not a comprehensive history. Freshpatents.com is not affiliated or associated with The Methodist Hospital in any way and there may be associated servicemarks. This data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for The Methodist Hospital with additional patents listed. Browse our Agent directory for other possible listings. Page by FreshPatents.com

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