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The Scripps Research Institute
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The Scripps Research Institute patents

Recent patent applications related to The Scripps Research Institute. The Scripps Research Institute is listed as an Agent/Assignee. Note: The Scripps Research Institute may have other listings under different names/spellings. We're not affiliated with The Scripps Research Institute, we're just tracking patents.

ARCHIVE: New 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "T" | The Scripps Research Institute-related inventors




Date The Scripps Research Institute patents (updated weekly) - BOOKMARK this page
10/12/17 new patent  Treatment of c9ftd/als by targeting rna expanded repeat sequences
10/05/17Reprogramming cells
09/28/17Process for the functionalization of heteroalkanes and arenes
09/14/17Generation and maintenance of stem cells
09/07/17Systems and methods for genomic annotation and distributed variant interpretation
08/24/17High-throughput screening for compounds modulating expression of cellular macromolecules
08/17/17Specific targeting of rna expanded repeat sequences
08/10/17Tlr-independent small molecule adjuvants
08/10/17Nanoparticle-based tumor-targeted drug delivery
08/03/17Small molecule inhibitors of fibrosis
08/03/17Sphinogosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders
08/03/17Polymerization method and polymers formed therewith
08/03/17Polymerization method and polymers formed therewith
07/27/17Constant region antibody fusion proteins and compositions thereof
07/27/17Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf
07/20/17Methods and compositions for enhancing cancer therapy
07/13/17Novel arenavirus vaccine
07/13/17Sulfur(vi) fluoride compounds and methods for the preparation thereof
07/06/17Pyrazole compounds and methods of making and using same
07/06/17Tissue molecular signatures of kidney transplant rejection
07/06/17Compositions and methods for fluid biopsy of melanoma
06/29/17N-hydroxy bicyclic hydantoin carbamates as tools for indetification of serine hydrolase targets
06/29/17Molecular signatures for distinguishing liver transplant rejections or injuries
06/15/17Compositions and methods for inducing immune tolerance
06/08/17Reprogramming of cells to a new fate
06/01/17N- (hydrophobe-substituted) vancosaminyl [psi-[c(=nh) nh] tpg4] vancomycin and [psi-[ch2nh]tpg4] vancomycin
05/25/17Methods and devices for detection and acquisition of biomarkers
05/18/17Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate
05/18/17Gene expression profiles associated with sub-clinical kidney transplant rejection
04/27/17Compounds and methods for inducing chondrogenesis
04/27/17Cysteine reactive probes and uses thereof
04/20/17Pharmacophore for trail induction
04/20/17Enantiopure haptens for nicotine vaccine development
04/13/17Trail enhancers for the selective killing of cancer cells
04/06/17Methods for modulating cancer cells and stem cells
03/23/17Combined chemical and genetic approaches for generation of induced pluripotent stem cells
02/23/17Novel modulators of sphingosine phosphate receptors
02/09/17Pparg modulators for treatment of osteoporosis
02/09/17Soluble hiv-1 envelope glycoprotein trimers
02/02/17Nkt cell ligands and methods of use
02/02/17Import of unnatural or modified nucleoside triphosphates into cells via nucleic acid triphosphate transporters
01/12/17Production of therapeutic proteins in photosynthetic organisms
01/05/17Targeting agent antibody conjugates and uses thereof
01/05/17Polymerization method and polymers formed therewith
12/29/16Methods and compositions for treating obesity
12/22/16Compositions and methods for treatment of neurodegenerative disease
12/22/16Compositions and methods for treating obesity
12/22/16Chemical approaches for generation of induced pluripotent stem cells
11/17/16Methods and compositions related to induced sensory neurons
11/03/16Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof
10/20/16Novel compounds as jnk kinase inhibitors
10/20/16Stem cell cultures
10/20/16Methods for the detection and quantification of circulating endothelial cells
10/06/16Modified therapeutic agents and compositions thereof
10/06/16Therapy for treatment or prevention of conditions associated with bleeding or hypocoagulation
10/06/16Novel hiv -1 broadly neutralizing antibodies
09/29/16Soluble hiv-1 envelope glycoprotein trimers
09/22/16Trail enhancers for the selective killing of cancer cells
09/22/16Glycopeptide antibiotic analogs effective against vancomycin-resistant bacterial strains
09/22/16Soluble hiv-1 envelope glycoprotein trimers
09/15/16Small molecule c-myc inhibitors
09/15/16Broadly neutralizing human immunodeficiency virus type 1 (hiv-1) gp120-specific monoclonal antibody
09/15/16Reprogramming of cells to a new fate
09/15/16Genotypic and phenotypic analysis of circulating tumor cells to monitor tumor evolution in prostate cancer patients
09/08/16Catalytic scavengers of organophosphates to potentiate butyrylcholinesterase (hbche) as a catalytic bioscavenger and methods for making and using them
Patent Packs
09/08/16Specific targeting of rna expanded repeat sequences
09/08/16Kappa opioid receptor effectors and uses thereof
09/08/16Reprogramming cells
09/01/16Composition for treating and preventing benign prostatic hyperplasia
09/01/16Cysteine-reactive ligand discovery in proteomes
08/25/16Expanded therapeutic potential in nitroheteroaryl antimicrobials
08/18/16Immunoglobulin fusion proteins and compositions thereof
07/28/16Mesenchymal stem cell differentiation
07/28/16Catalysed ligation of azides and acetylenes
07/21/16Modularly assembled small molecules for the treatment of myotonic dystrophy type 1
07/14/16Enhancing efficiency of retroviral transduction of host cells
07/07/16Compounds for treatment of drug resistant and persistent tuberculosis
07/07/16Targeted covalent probes and inhibitors of proteins containing redox-sensitive cysteines
06/30/16Derivatives of uncialamycin, methods of synthesis and their use as antitumor agents
06/30/16Bidentate-binding modulators of lrrk2 and jnk kinases
Patent Packs
06/30/16Engineered outer domain (eod) of hiv gp120 and mutants thereof
06/30/16Transcriptome-wide design of selective, bioactive small molecules targeting rna
06/23/16Conversion of alkanes to organoseleniums and organotelluriums
06/16/16Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate
06/16/16A the site-specific enzymatic labelling of nucleic acids in vitro by incorporation of unnatural nucleotides
06/09/16Antibody targeting through a modular recognition domain
05/26/16Compositions and methods for treating charcot-marie-tooth diseases and related neuronal diseases
05/19/16Preparation of (s,s)-secoisolariciresinol diglucoside and (r,r)-secoisolariciresinol diglucoside
05/12/16Small molecule inhibitors of fibrosis
04/28/16Targeting agent antibody conjugates and uses thereof
03/10/16Vault complexes for facilitating biomolecule delivery
03/03/16Methods and compositions for treating bleeding disorders
02/25/16Substituted benzimidazoles as nociceptin receptor modulators
02/18/16Compounds and methods for inducing chondrogenesis
02/18/16Systems and methods for genomic annotation and distributed variant interpretation
02/04/16Mammalian protein co-recognition by broadly neutralizing antibodies as modified immunogens for re-elicitation
01/21/16Bispecific antibodies and uses thereof
01/21/16Collection of probes for autistic spectrum disorders and their use
01/07/16Neoseptins: small molecule adjuvants
01/07/16Oxidation of alkanes to alcohols
12/31/15Modulators of vasopressin receptors with therapeutic potential
12/31/15Peptoids that bind specific antigens
12/17/15Centrally active and orally bioavailable antidotes for organophosphate exposure and methods for making and using them
12/17/15Broadly neutralizing antibody and uses thereof
12/10/15Methods and compositions for enhancing transduction efficiency of retroviral vectors
11/05/15Polymerization method and polymers formed therewith
11/05/15Methods and compositions related to modulators of eukaryotic cells
10/29/15Small molecules targeting repeat r(cgg) sequences
10/15/15C20' urea derivatives of vinca alkaloids
10/08/15Chimeric polypeptides having targeted binding specificity
Social Network Patent Pack
10/01/15Wee1 degradation inhibitors
09/24/15Translational enhancer-element dependent vector systems
09/03/15Klf5 modulators
09/03/15Immunoglobuljin-binding human mycoplasma antigens and methods of use thereof
08/27/15Immunogens of hiv-1 broadly neutralizing antibodies, methods of generation and uses thereof
08/27/15Induction of pluripotent cells
08/27/15Expanding the eukaryotic genetic code
08/20/15Substituted pyrimidinyl-amines as protein kinase inhibitors
08/20/15Copper-catalysed ligation of azides and acetylenes
08/06/15Monoclonal antibodies directed against trimeric forms of the hiv-1 envelope glycoprotein with broad and potent neutralizing activity
Patent Packs
07/30/15Novel kappa opioid ligands
07/02/15Circulating tumor cell diagnostics for lung cancer
06/25/15Dna composition for eliciting an immune response against tumor-associated macrophages
06/04/15Chromosomal landing pads and related uses
06/04/15Systems and methods for genomic annotation and distributed variant interpretation
05/28/15Novel phenyl glyoxal probes
05/28/15Carbamate compounds and of making and using same
05/14/15Monomeric forms of human aminoacyl-trna synthetases having non-canonical biological activities
05/07/15Antibiotic compounds and compositions, and methods for identification thereof
04/02/15Preparation of specimen arrays on an em grid
04/02/15Small molecule myristate inhibitors of bcr-abl and methods of use
03/19/15Generation and maintenance of stem cells
03/19/15Treatment of friedreich's ataxia using histone deacetylase inhibitors
02/26/15Cyclic prodrugs of duocarmycin analogs
02/12/15Polypeptides and their use in treating metapneumovirus (mpv) infection
02/12/15Broad spectrum antibiotic arylomycin analogs
01/29/15Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf
01/29/15Copper-catalysed ligation of azides and acetylenes
01/15/15Carbamate compounds and of making and using same
01/15/15Unnatural reactive amino acid genetic code additions
01/08/15Humanized antibodies
01/08/15Difluoromethylation of unsaturated compounds
12/25/14Tyrosine bioconjugation through aqueous ene-like reactions
12/18/14Reengineering mrna primary structure for enhanced protein production
12/18/14Kappa opioid receptor effectors and uses thereof
11/13/14Non-invasive early detection of solid organ transplant rejection by quantitative analysis of mixtures by deep sequencing of hla gene amplicons using next generation systems
11/06/14Virucidal small molecule and uses thereof
10/30/14Dna vaccines against tumor growth and methods of use thereof
10/30/14Engineered outer domain (eod) of hiv gp120 and mutants thereof
10/09/14Hiv-1 gp120 mini v3 loop and uses thereof
Patent Packs
09/18/14Chiral compounds of varying conformational rigidity and methods of synthesis
09/18/14Stem cell cultures
08/21/14Image analysis platform for identifying artifacts in samples and laboratory consumables
07/24/14Human immunodeficiency virus (hiv)-neutralizing antibodies
07/03/14Modulators of the nuclear hormone receptor ror
06/19/14Production of carrier-peptide conjugates using chemically reactive unnatural amino acids
05/15/14Methods for treating transthyretin amyloid diseases
05/08/14Human aminoacyl-trna synthetase polypeptides useful for the regulation of angiogenesis
05/08/14Multispecific antibody targeting and multivalency through modular recognition domains
04/24/14Compounds and methods for inducing chondrogenesis
04/03/14Chemically programmed vaccination
03/27/14Ultralong complementarity determining regions and uses thereof
03/06/14Copper-catalysed ligation of azides and acetylenes
02/20/14Ultralong complementarity determining regions and uses thereof
02/20/14Direct reprogramming of human fibroblasts to functional neurons under defined conditions
02/13/14Tetracyclic inhibitors of fatty acid amide hydrolase
02/06/14Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate
02/06/14High-throughput screening for compounds modulating expression of cellular macro-molecules
01/16/14Palladium(ii)-catalyzed selective fluorination of benzoic acids and derivatives
12/19/13Alpha-ketoheterocycles and methods of making and using
Social Network Patent Pack
11/21/13Methods and compositions for the production of orthogonal trna-aminoacyl trna synthetase pairs
11/07/13Methods and compositions for treating disorders associated with hyperactive immune system
10/24/13Reprogramming of cells to a new fate
10/24/13Inhibitors of focal adhesion kinase
10/24/13Anti-cancer serine hydrolase inhibitory carbamates
09/26/13Novel hiv -1 broadly neutralizing antibodies
09/26/13Methods for the detection of circulating tumor cells
09/19/13Orthogonal translation components for the in vivo incorporation of unnatural amino acids
09/19/13Unnatural reactive amino acid genetic code additions
09/05/13Substituted pyrimidinyl-amines as protein kinase inhibitors
08/15/13Crystals of membrane proteins
08/15/13Treatment of friedreich's ataxia using histone deacetylase inhibitors
08/01/13Compositions and methods for inducing cell dedifferentiation
07/11/13Compositions and methods related to mrna translational enhancer elements
07/04/13Targeting compounds
06/27/13Enzyme regulating ether lipid signaling pathways
03/28/13Artificial immune system: methods of use
03/07/13Methods of generating pluripotent stem cells
02/28/13Monomeric forms of human aminoacyl-t-rna synthetases having non-canonical biological activities
02/28/13Natural antisense and non-coding rna transcripts as drug targets
Social Network Patent Pack
12/27/12Genetically encoded fluorescent coumarin amino acids
12/27/12Novel modulators of sphingosine phosphate receptors
12/27/12Novel modulators of sphingosine phosphate receptors
12/27/12Novel modulators of sphingosine phosphate receptors
11/29/12C4-substituted alpha-keto oxazoles
11/15/12Tyrosine bioconjugation through aqueous ene-like reactions
11/08/12Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells
11/08/12Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine
11/08/12Expanding the eukaryotic genetic code
10/18/12Human aminoacyl-trna synthetase polypeptides useful for the regulation of angiogenesis
10/18/12Induction of pluripotent cells
10/11/12Chromosomal landing pads and related uses
10/04/12Systems for the expression of orthogonal translation components in eubacterial host cells
10/04/12Expanding the eukaryotic genetic code
09/20/12Tryptophanyl-trna synthetase-derived polypeptides useful for the regulation of angiogenesis
09/13/12Miniaturized electroporation-ready microwell aray for high-throughput genomic screening
09/06/12Nicotine haptens, immunoconjugates and their uses
08/09/12In vivo incorporation of unnatural amino acids
07/19/12Genetically programmed expression of selectively sulfated proteins in eubacteria
07/12/12Adult animals generated from induced pluripotent cells
07/12/12Gene expression profiles associated with chronic allograft nephropathy
06/28/12Copper-catalysed ligation of azides and acetylenes
06/21/12Compositions and methods for inducing neuronal differentiation
05/24/12Compositions of orthogonal lysyl-trna and aminoacyl-trna synthetase pairs and uses thereof
05/17/12Human aminoacyl-trna synthetase polypeptides useful for the regulation of angiogenesis
05/17/12Human a2a adenosine receptor crystals and uses thereof
04/26/12Site-specific incorporation of redox active amino acids into proteins
04/26/12Crystals of membrane proteins
04/26/12Methods and compositions for the production of orthogonal trna-aminoacyl trna synthetase pairs
03/15/12Methods for treating transthyretin amyloid diseases
Social Network Patent Pack
03/08/12Erbb2 antibodies comprising modular recognition domains
03/08/12Nanoparticle-based tumor-targeted drug delivery
02/16/12Methods for diagnosing cancer and decreasing metastasis by cancer cells
02/16/12Dna composition encoding an immunogenic vegf receptor peptide and methods of use thereof
02/09/12Egfr antibodies comprising modular recognition domains
02/02/12Generation and maintenance of stem cells
01/26/12Multispecific antibody targeting and multivalency through modular recognition domains
01/26/12Vegf antibodies comprising modular recognition domains
01/19/12Angiogenic tyrosyl t-rna synthetase compositions and methods
01/12/12Isolated monocyte populations and related therapeutic applications
01/05/12Unnatural reactive amino acid genetic code additions
12/29/11Site specific incorporation of keto amino acids into proteins
12/22/11Chemically programmed vaccination
12/22/11Agents for hcv treatment
12/08/11Inhibiting tumor cell invasion, metastasis and angiogenesis
12/08/11Exponential isothermal self-sustained replication of an rna enzyme
12/01/11Stem cell cultures
11/10/11Methods and compositions related to targeting monoacylglycerol lipase
10/20/11Image analysis platform for identifying artifacts in samples and laboratory consumables
09/22/11Crystal of a cytochrome-ligand complex and methods of use
09/15/11Stem cell cultures
09/08/11Expanding the eukaryotic genetic code
07/28/11Alpha-keto heterocycles as faah inhibitors
07/14/11Novel subtype of closteridium botulinum neurotoxin type a and uses thereof
06/23/11Benzopyrans and analogs as rho kinase inhibitors
06/09/11Human antibodies neutralizing human metapneumovirus
05/26/11Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells
05/26/11Translation enhancer-element dependent vector systems
05/12/11Human aminoacyl-trna synthetase polypeptides useful for the regulation of angiogenesis







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